Palb009493.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Philonicus albiceps
Gene Symbol
ZEB2
Assembly
GCA_963969385.1
Location
OZ017772.1:70262872-70273200[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.00015 0.022 16.0 2.9 1 23 280 302 280 302 0.99
2 21 0.19 28 6.3 0.1 2 23 308 328 307 328 0.95
3 21 0.075 11 7.6 0.2 2 23 335 356 334 356 0.95
4 21 0.00076 0.11 13.8 1.1 1 23 399 422 399 422 0.95
5 21 2.7e-05 0.0039 18.4 2.2 1 23 433 455 433 455 0.96
6 21 2.5e-05 0.0036 18.5 2.4 1 23 461 483 461 483 0.95
7 21 1.1e-05 0.0016 19.6 6.8 1 23 489 511 489 511 0.97
8 21 0.00012 0.018 16.3 0.2 2 23 544 565 543 565 0.97
9 21 0.17 25 6.4 0.9 1 23 571 593 571 593 0.77
10 21 2.4e-05 0.0035 18.5 3.6 1 23 599 621 599 621 0.96
11 21 0.00015 0.022 16.0 0.3 1 23 627 649 627 649 0.98
12 21 0.00036 0.052 14.9 6.5 1 23 654 677 654 677 0.96
13 21 0.014 2 9.9 1.7 1 23 907 929 907 929 0.93
14 21 0.17 24 6.5 0.0 3 23 963 984 962 984 0.96
15 21 1.1 1.7e+02 3.8 1.2 1 23 999 1022 999 1022 0.89
16 21 0.0022 0.32 12.4 3.2 1 23 1030 1053 1030 1053 0.98
17 21 0.00031 0.045 15.0 0.2 2 23 1069 1090 1068 1090 0.97
18 21 0.17 25 6.4 0.9 1 23 1096 1118 1096 1118 0.77
19 21 1.2e-05 0.0017 19.5 3.4 1 23 1124 1146 1124 1146 0.96
20 21 0.00035 0.05 14.9 0.2 1 23 1152 1174 1152 1174 0.97
21 21 0.00036 0.052 14.9 6.5 1 23 1179 1202 1179 1202 0.96

Sequence Information

Coding Sequence
ATGGATTGGTCCCAGGAAGGGTGTACTTCCACAGTATATGCGGATGAACGATTTGAAGAATTTTGCGAGAATAAGCAAGAGAAGCTAAAGAAGGAAGTAATCACGTTCCTTGAGGTTGACCccttaaaatatgaaattgagGAAACTCCTGTAGAAGATATGTGTAATAAAGACACTACTACAACTAATGTTGCCGATACAAAATGTGAAACTGTGGagattatcgACAGTGACGATGAGAATCTACCAGATAAAACTTATGAAGAGCACAATAATGTAGTAGGAAAGGAACAATCATCGCCAAATAAAACGcaaaaagagttcaaaattaaaatggaaagttTTGATACCGATGACTCGCAgcataaactaaatttagcGAAGCAATCAATTGAATATCCTTCAATGAACTTAGGCAAAGATAAGGCCACCAAATCAATACAAAAGGAGGAAATGCCTGGTATTAGTCATATACAGAACGATGTTATTAAAGAAGAAACTCAATTCGATGATGCAgaaataaagatttataaatcaaatgaaaaagttttacaagATGAAGATCATTGTGAAGAAGGAGGAATGGAGAAAATCGCCGAGGGTCATCTAAATGTGGAAATGTTAGATGATGATATTGAAGATCAGCACTGCGATGAGGAGAGGTTGGAGGAGGAAAACGAAGATCAGCACCAAGATAAGGAAACATTAGAGgatgtaaatgaaaatcaattctcATACCAAAAACCTGAGAACGAAACTTTGAAATCAAGCAGTTACTCTGATAATTTCAATGATTATGATGATTATAATGACTTTGATGGAAATGTTTTCGAAATCTTTAAATGCAGTATGTGCTTAAAGGAATTTgatgataaaaaattgttcgacCGACATCAGAGGACCcacattgaaacaaaaataaaatgccctTTTTGTCCCAAAGCAGTAGGGAAGAGATCAATGAAAGTACATCTTGCTACACACAAGGAGATCGATAAGTTAATCTGTGATCAATGCGGAGATGTCTTTAATAATGTGTTTGTACTTTTCAAACACCTCAAGcaacataaaacaaatgttagGGAGGAGGCGAAGTATATTTACAGTTGCGACTTATGCGAAGATCAGAACGTGAGTTTATTAACACATCAGAACCATATGAGAAGTACGCACGGTTTAGAAGACCCAAGACCCTTCAAGTGTAAACAATGCCAAATAGGATTCACTAGGAAGCAGGGTATGTATCGGCACATTGAAAATGTACACAAACGAAAAGATAAGGACCGAGTAAAAGACTTCCTCTGCAACATTTGCGGGAAAAACTTTTACGTGAAATTCCATCTAGATATCCATATGCGTTCGCATACTGGAGAACGTCCTCACAAATgtaaatattgtgaaaaagCTTTTACCCAACTTTCTGCTTTAAGGACTCACGAATACATTCACACTGGCGAAAAACCTTTTGCATGCAAACattgtggaaaaaaatttaagcaatacGGCCACCTTACGTACCATCAACAAACGCATGCGGAGGGATTTCCATATGACTCTCTTTTACACCATTATAAAAGGGATCACAATCCTCATAAAGAAGATTTGGAAAAGAAAGAATCGGAAAGGCTTACCTGTGTGATTTGTGATGGAAGCTACTCTTCAAAATTGAGTCTTGTAAGGCATATGCGTATGCATACCGGAGAACGACCCTACAAGTGTGACGAATGCGGGGAGCGATTCTGGAACGTTGCGTCCAAACATCAACATAAACTTATACATACGGGTGAAAAGCCCTATCTTTGCAGTATATGCGGAAAAGGATTCAAGCAATTCAGTCATTTTCAGTACCATCAAAATATGCATGCAGATGTCCGACCTTACGTTTGCAACATATGCAACAGTGCATTCCGGGTGAAGGGCGCCCTCACTACCCACAAGAAAATTCATGGTGAAAAGAAATTCTGTTGCGAAATTTGTGATAAACGTTTCACAATGCGATGTGCGTTAAGCAAACATATGAGACAAAAACATAGTAATATTCAACAAACaactgaaattaaaCTTTTGTATGGCAATATAAGAACAGAGGATGTAATACTAGATGAAATGGATTGGTCCCAGGAAGGGTGTACTTCCACAGTATATGCGGATGAACGATTTGAAGAATTTTGCGAGAGTAAGCAAGAGAAGCTAAAGAAGGAAGTAATCACGTTCCTTGAGGTTGACCccttaaaatatgaaattgagGAAACTCCTGTAGAAGATATGTGTAATAAAGACACTACTACAACTAATGTTGCCGATACAAAATGTGAAACTGTGGagattatcgACAGTGACGATGAGAATCTACCAGATAAAACTTATGAAGAGCACAATAATGTAGTAGGAAAGGAACAATCATCGCCAAATAAAACGGCAAAGATTTTAAGTGATgtcaaaattatagaaaataccAAAAACGATGATAACATTAATTGCGAAATTAAAGATGAACAAAAAGATAATAACGTCAATATCGAAAATATCAATGGAGCCGGGCATGATGATGTATcacataaacatttaaatatcagTGAAAATGATAATTCATGTGATCCATGTGATGCAATGCCAGAAGTAAGCAAACAGGAAAATCAAGTTTATATAGAAGCAGTTGAAGGTGCaaatgaaaatgcaaaagaCGTAGTCCAGCTTGCTACACTTGTTCCTGAGTTGTACATCTGCATTGTGTGTTCAAGGAAATATGAAACCCTTTCGTCTTTTAAACGTCATCAGCAATACCATAGGAGCAAAATGGTTAAATGTCCTATTTGTTcgaaacatattaaattaaaatctattaagaAACACGTATTTCATCATAAACAGAGACTTGAGCTATTATGCGGCGAATGTGGAGATCGTTATGATAATTTGGAGGACCTATTCGAGCACATAGTAACATCACATGGAAAAAGGATTAAAACTAcaagagaatatttttactatatctaCGAATGCGATTTGTGTGATTATAAAACGGCTTCACGAGTATCGCATCGGAATCACTTAACACAAATCCATAATACAActgataaatttgtttttaaatgtaccGATTGCATTAAACGCTACACATCGAAAGCAGCTCTTTTACACCATTATAAAAGGGATCACAATCCTCATAAAGAAGATTTGGAAAAGAAAGAATCGGAAAGGCTTACCTGTGTGATTTGTGATGGAAGCTACTCTTCAAAATTGAGTCTTGTAAACCACATGCGTATGCATACCGGAGAACGACCCTACAAGTGTGACGAATGCGGGGAGCGATTCTGGAACGTTGCGTCCAAACATCAACATAAACTTATACATACGGGTGAAAAGCCCTATCTTTGCAGTATATGCGGAAAAGGATTCAAGCAATATAGTCACTTTCAGTACCATCAAAATATGCATGCAGATGTCCGACCTTATGCTTGCAACATATGCAACAGTGCATTCCGGGTGAAGGGCGCCCTCACTACCCACAAGAAAATTCATGGTGAAAAGAAATTCTGTTGCGAAATTTGTGATAAACGTTTCACAATGCGATGTGCGTTAAGCAAACATATGAGACAAAAACATAGTAATATTCAACAAACaactgaaattaaagtaagtccaataattagttaa
Protein Sequence
MDWSQEGCTSTVYADERFEEFCENKQEKLKKEVITFLEVDPLKYEIEETPVEDMCNKDTTTTNVADTKCETVEIIDSDDENLPDKTYEEHNNVVGKEQSSPNKTQKEFKIKMESFDTDDSQHKLNLAKQSIEYPSMNLGKDKATKSIQKEEMPGISHIQNDVIKEETQFDDAEIKIYKSNEKVLQDEDHCEEGGMEKIAEGHLNVEMLDDDIEDQHCDEERLEEENEDQHQDKETLEDVNENQFSYQKPENETLKSSSYSDNFNDYDDYNDFDGNVFEIFKCSMCLKEFDDKKLFDRHQRTHIETKIKCPFCPKAVGKRSMKVHLATHKEIDKLICDQCGDVFNNVFVLFKHLKQHKTNVREEAKYIYSCDLCEDQNVSLLTHQNHMRSTHGLEDPRPFKCKQCQIGFTRKQGMYRHIENVHKRKDKDRVKDFLCNICGKNFYVKFHLDIHMRSHTGERPHKCKYCEKAFTQLSALRTHEYIHTGEKPFACKHCGKKFKQYGHLTYHQQTHAEGFPYDSLLHHYKRDHNPHKEDLEKKESERLTCVICDGSYSSKLSLVRHMRMHTGERPYKCDECGERFWNVASKHQHKLIHTGEKPYLCSICGKGFKQFSHFQYHQNMHADVRPYVCNICNSAFRVKGALTTHKKIHGEKKFCCEICDKRFTMRCALSKHMRQKHSNIQQTTEIKLLYGNIRTEDVILDEMDWSQEGCTSTVYADERFEEFCESKQEKLKKEVITFLEVDPLKYEIEETPVEDMCNKDTTTTNVADTKCETVEIIDSDDENLPDKTYEEHNNVVGKEQSSPNKTAKILSDVKIIENTKNDDNINCEIKDEQKDNNVNIENINGAGHDDVSHKHLNISENDNSCDPCDAMPEVSKQENQVYIEAVEGANENAKDVVQLATLVPELYICIVCSRKYETLSSFKRHQQYHRSKMVKCPICSKHIKLKSIKKHVFHHKQRLELLCGECGDRYDNLEDLFEHIVTSHGKRIKTTREYFYYIYECDLCDYKTASRVSHRNHLTQIHNTTDKFVFKCTDCIKRYTSKAALLHHYKRDHNPHKEDLEKKESERLTCVICDGSYSSKLSLVNHMRMHTGERPYKCDECGERFWNVASKHQHKLIHTGEKPYLCSICGKGFKQYSHFQYHQNMHADVRPYACNICNSAFRVKGALTTHKKIHGEKKFCCEICDKRFTMRCALSKHMRQKHSNIQQTTEIKVSPIIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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