Basic Information

Insect: Philonicus albiceps
Gene Symbol: topi
Assembly: GCA_963969385.1
Location: OZ017773.1:28092496-28094019[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0012 0.17 13.3 0.1 2 23 11 32 10 32 0.96

2 16 0.55 79 4.8 0.1 3 11 51 59 50 62 0.87

3 16 0.018 2.5 9.5 0.1 3 23 92 113 91 113 0.92

4 16 1.6 2.2e+02 3.4 7.3 1 23 119 141 119 141 0.95

5 16 0.00027 0.039 15.2 1.0 1 23 147 169 147 169 0.96

6 16 2.2e-07 3.1e-05 25.0 0.3 1 23 177 199 177 199 0.98

7 16 0.0005 0.072 14.4 0.7 1 23 206 228 206 228 0.99

8 16 2.8e-05 0.004 18.3 2.4 1 23 234 256 234 256 0.98

9 16 0.0007 0.1 13.9 0.9 3 23 266 286 266 286 0.99

10 16 4.5e-06 0.00066 20.8 0.4 1 23 293 315 293 315 0.98

11 16 2.9e-06 0.00042 21.4 0.2 1 23 321 343 321 343 0.97

12 16 0.00012 0.018 16.3 0.4 2 23 352 373 351 373 0.97

13 16 0.00011 0.016 16.5 2.5 1 23 381 403 381 403 0.97

14 16 0.002 0.29 12.5 2.4 1 20 409 428 409 429 0.92

15 16 0.24 35 5.9 5.5 1 23 439 461 439 461 0.97

16 16 0.00041 0.059 14.7 2.0 1 23 465 487 465 487 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0012	0.17	13.3	0.1	2	23	11	32	10	32	0.96
2	16	0.55	79	4.8	0.1	3	11	51	59	50	62	0.87
3	16	0.018	2.5	9.5	0.1	3	23	92	113	91	113	0.92
4	16	1.6	2.2e+02	3.4	7.3	1	23	119	141	119	141	0.95
5	16	0.00027	0.039	15.2	1.0	1	23	147	169	147	169	0.96
6	16	2.2e-07	3.1e-05	25.0	0.3	1	23	177	199	177	199	0.98
7	16	0.0005	0.072	14.4	0.7	1	23	206	228	206	228	0.99
8	16	2.8e-05	0.004	18.3	2.4	1	23	234	256	234	256	0.98
9	16	0.0007	0.1	13.9	0.9	3	23	266	286	266	286	0.99
10	16	4.5e-06	0.00066	20.8	0.4	1	23	293	315	293	315	0.98
11	16	2.9e-06	0.00042	21.4	0.2	1	23	321	343	321	343	0.97
12	16	0.00012	0.018	16.3	0.4	2	23	352	373	351	373	0.97
13	16	0.00011	0.016	16.5	2.5	1	23	381	403	381	403	0.97
14	16	0.002	0.29	12.5	2.4	1	20	409	428	409	429	0.92
15	16	0.24	35	5.9	5.5	1	23	439	461	439	461	0.97
16	16	0.00041	0.059	14.7	2.0	1	23	465	487	465	487	0.97

Sequence Information

Coding Sequence: atgtactgcGAAGATTGGTTGAATTCTCTCAGCTGTGACGACTGCGGTGCACAATTTGTCGATATAAGAACTTTTATGGCACAcaggaaaattcattttgcacCACCGCCtgatattcaattaaaagaaaaagacgTTCTGAATGGAATTTGTCCCTACTGCAATTTGTCTTTTAACGTTAAAATCTTACGCCCCGAAGTGGTTGAAGAAATCCAACGATTAAAGAATGGTCAGaaacaaaatggaaaattaaaaataagggaaTGCAGGTACTGCTTTATATGTGAAATATCGTTTCAAAATGCGATTGAGCTGCTCAAACATTCGAAGGAAGTCCACGACATCGAGCGTCCTTATCAGTGCaagaaatgcaattttactACTTCTATCTTTCATCACGTAAAAAGGCACTCCTACGTCCATAAGAAAACGAAACTTTTCACCTGCCACCTCTGCCCGAAGGCGTATTCGTCAAAAGCCTCATTAGATGGGCATTTTCTGATGCATTCTGAGGTTAGTATAAAATCGTACGACTGCGATATTTGTGGCAAGAAGTTTCCAATTCCATCTCAGCTTAAAAAACACTTGAAGATGCATGAGCCTGCCGAgaagttttataaatgtgACTTATGCCCCAAGGAGTATGTGTGGAAGAGCAGCTTGAAAATGCACAAGTTGACTCACACCGGAGAGAGGCCTTTTCGATGCCAAATTTGCAAAAGAGGATTCACGGAGGCGTTTAAATACAGACGACACATGAAGGTGCACAATCAAATCATAGGGAAAGTAATTGGTTGCGAATTATGCGATAAGCAATTCCATGCTGCATATTTGCTTAAAAACCATATGCTCGTTCATGAGAAAAATGAATCCCGATTCATTTGCGACGTCTGCTCGAAACCATTCATGCGGGAGgcgaatttgaatttgcataGAAGAACTCATAGTGGCGATGCGCCCTACGCTTGCGAGGACTGTGGTAAGAAATTCGCAAATCGTTGGGGGTACATCAGGCACAGACAAATTCACGTAAAACCTAATGACCACCCGGTCGAATGTGAACACTGTGGAAAGGAGTTTGCTGCGATGTACCGACTCGAAAGACACCTGAAAATTCACACTCGTGACGGGGACGATCTTCATAAGTGCGAGATTTGTTCTAAGCtttttacaagaaaacaaGCCTTAAAAGATCATACTCTACTACACGAGGGCAAAGAGCCCTTCCATTGCATTCattgtggaaaaaaatttgttaaacaaaaGCAGTTGAAGGTTCACCTTGATCCTGATAGAAGGAGCTCTTCAAGAGCCTTCAGGTGCAAAGCGTGCTCTAAGATTTTCCCGACTAGAAGTTGCTACTTATTCCACAAAAGAACTCacaaaaaggaatatttttgcGAAACGTGCGGCAGTAAGTTCTACACAAGATTCggattaaaaaaacatttaaatggtCATGTTAAGGGCGAAGTAACAGATCTTGACGATGagtttatcaaagaaaaatgtagCAAAAATTAG
Protein Sequence: MYCEDWLNSLSCDDCGAQFVDIRTFMAHRKIHFAPPPDIQLKEKDVLNGICPYCNLSFNVKILRPEVVEEIQRLKNGQKQNGKLKIRECRYCFICEISFQNAIELLKHSKEVHDIERPYQCKKCNFTTSIFHHVKRHSYVHKKTKLFTCHLCPKAYSSKASLDGHFLMHSEVSIKSYDCDICGKKFPIPSQLKKHLKMHEPAEKFYKCDLCPKEYVWKSSLKMHKLTHTGERPFRCQICKRGFTEAFKYRRHMKVHNQIIGKVIGCELCDKQFHAAYLLKNHMLVHEKNESRFICDVCSKPFMREANLNLHRRTHSGDAPYACEDCGKKFANRWGYIRHRQIHVKPNDHPVECEHCGKEFAAMYRLERHLKIHTRDGDDLHKCEICSKLFTRKQALKDHTLLHEGKEPFHCIHCGKKFVKQKQLKVHLDPDRRSSSRAFRCKACSKIFPTRSCYLFHKRTHKKEYFCETCGSKFYTRFGLKKHLNGHVKGEVTDLDDEFIKEKCSKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00717979;
90% Identity: -
80% Identity: -