Basic Information

Gene Symbol
-
Assembly
GCA_963565745.1
Location
OY751435.1:2098400-2105738[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.003 0.38 12.5 0.2 3 20 35 52 34 53 0.96
2 12 0.039 4.9 9.0 9.0 1 23 70 93 70 93 0.95
3 12 4.2 5.3e+02 2.6 0.1 2 23 101 123 100 123 0.88
4 12 6e-05 0.0075 17.9 0.6 1 21 128 148 128 149 0.96
5 12 2.8e-08 3.6e-06 28.3 0.5 1 23 160 183 160 183 0.97
6 12 0.22 28 6.7 5.0 1 23 189 212 189 212 0.95
7 12 0.00061 0.076 14.7 1.0 1 23 218 240 218 240 0.97
8 12 0.047 6 8.8 1.1 1 23 245 267 245 267 0.98
9 12 0.00015 0.019 16.6 2.3 1 23 273 295 273 295 0.98
10 12 0.002 0.26 13.1 0.7 1 22 298 319 298 320 0.89
11 12 0.00075 0.094 14.4 3.8 1 23 360 382 360 382 0.98
12 12 1 1.3e+02 4.6 0.2 3 23 390 413 389 413 0.83

Sequence Information

Coding Sequence
ATGTCATTACAGCGCAAGAGACGAGGTAGACCTCCAGGTTCAAAGAACAAAATTAAACTGAACCCGAGCATTAAGCTTGAAGAAAATGACGATGAGTTGCTTTGCAAGATGTGTAAATTATCATTCACATCAATATCTGAGCTTCAATCGCATTTAGGCGGTTGCAAATATTTGTGTAAAGAACTAAAATTTAAAGCAAAGCCTAACTATCATTGCAACAAAtgcagaaaaaaatttaaattgaagtCATGCTTTAAGACCCATCTGTTGAATGAGCATTCCCAAACCCCTGGTAGTGTTCCATGTGAACAGTGCCACGTCGTTTGTCCTAATATTGAGGTACTGGGGACCCATATTGCTAATGTACATGAGAGAAGCATATATGAGTGTGAGTTTTGTGAGAAGAAGTTTGTACGCCAGGCCCATGTCATACGGCATATGTCACAAACTGGTTGTGATGGAAAAGGAAAACTTCTGTATCCATGTGAAatATGCAACAAGACCTTTTCAAGGAAAGATAACTTGATGGTACATCTGAGACTGAACCACATCTCTAAGAAGAGCTTTAGCTGCAAGAACTGTAATTTCTCAACTAACAATTTTTCAAAACTTGTTCTACATCATCAAAACAAACATCAAAaaaaatcacaTTTTGAATGCCATCACTGTGGTAAAGTTACAGGATCGAGAGCCGCAATTTCAAAACATTTGGAAATCCACGGCGAAAAGAAATACAAATGTGAtgtgTGTGGCCACAACACGTTCACGATCGAGGTGATGCGTCGCCACGTCCTCACCCACATTCCGAACAAGCCGCACAAGTGCAAAATCTGCGGCAGCTCGTACATACAGAAGCTGCAGCTCGATCGCCACATGCTGAAACACATCGGATTCCCGTGCCGCAAGTGCGGCATGATGTTTGAGACCAAATCTAAGTTCTTGGCACATGACAAGATTCACGTGAAAAAGGGACCAATACTCTGCCCGTTTGGAGACTGTGAATACGCCAAAAAAGAACTCGTAGACATGGAAACTTATAACGAACATATAAAAGAACACAGCACCATAGACAAGTTGTACGAGTGCAACGTGTGTAACAAGACATTCAACTGCGAGTCGTTCCTGCGGCGGCACGTGAGCACGCACGCCCTGGAGCGCGCGCGCCGCTGCATGTACTGCGTCACGGCGCGGGCGTACGCGCGCGGAGAGCAGCTCGTGCGCCACGTGCGGACCAAGCACCCCGACGTGTTCCGCGCGCGCCTGCAGCACGTGCGCGACGTGCTAGGCTCAACGCTGACGGGGTCGCGTGTGACGAAGTCGGAGATGGAGTCGGTGCTGAACGTGCTGGACGCGGAGACAGACCGCATCCTGGAGGACTACGGCCCGGGCGTGCTGTACGGCGGCTTGCAGGAGGACACAGCTGAGGCGGAGGAGATTCAGaTGCAGAACAATAGCGAAGAGTCGCCGCTGATGAGTGAGACTGAGCTGGAGGAGCACCTGCGCCGCCTGCTGTCGCAGTTGATAGAGCGCGACGTGTTAGAGTACTTCGGCTGGCCCGACGAGAACGTCGACACGGTGCTAGAGAAAGTGATAGAGAAGATGGGGGCGCGCGCGGCGCCGCGGGACAAGTGGTCGCGCGTGCAGCGGCTGCGCGAGAACACGAAGCATCTGTTCCTGCACGCGGTCGAAGACACGGCCATCGCGCGCATGCTGGACACGCACACCATCGACCAAGTCGTCAAGCATATTCTCGCAAAAGTTACAACCAATGTGAAACTTGAAGATGAGTCCTCTCTAAAGAAAGAAGCtgaagtttaa
Protein Sequence
MSLQRKRRGRPPGSKNKIKLNPSIKLEENDDELLCKMCKLSFTSISELQSHLGGCKYLCKELKFKAKPNYHCNKCRKKFKLKSCFKTHLLNEHSQTPGSVPCEQCHVVCPNIEVLGTHIANVHERSIYECEFCEKKFVRQAHVIRHMSQTGCDGKGKLLYPCEICNKTFSRKDNLMVHLRLNHISKKSFSCKNCNFSTNNFSKLVLHHQNKHQKKSHFECHHCGKVTGSRAAISKHLEIHGEKKYKCDVCGHNTFTIEVMRRHVLTHIPNKPHKCKICGSSYIQKLQLDRHMLKHIGFPCRKCGMMFETKSKFLAHDKIHVKKGPILCPFGDCEYAKKELVDMETYNEHIKEHSTIDKLYECNVCNKTFNCESFLRRHVSTHALERARRCMYCVTARAYARGEQLVRHVRTKHPDVFRARLQHVRDVLGSTLTGSRVTKSEMESVLNVLDAETDRILEDYGPGVLYGGLQEDTAEAEEIQMQNNSEESPLMSETELEEHLRRLLSQLIERDVLEYFGWPDENVDTVLEKVIEKMGARAAPRDKWSRVQRLRENTKHLFLHAVEDTAIARMLDTHTIDQVVKHILAKVTTNVKLEDESSLKKEAEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00406144;
90% Identity
iTF_00289153;
80% Identity
-