Basic Information

Insect: Phengaris arion
Gene Symbol: topi
Assembly: GCA_963565745.1
Location: OY751447.1:2538484-2556453[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00019 0.024 16.3 1.2 1 23 260 282 260 282 0.98

2 12 6.8e-05 0.0086 17.7 1.7 2 23 290 311 289 311 0.96

3 12 0.4 51 5.8 0.9 1 23 315 337 315 337 0.98

4 12 0.00033 0.041 15.5 1.2 1 23 342 365 342 365 0.98

5 12 0.0039 0.49 12.2 0.8 1 23 369 392 369 392 0.94

6 12 0.069 8.6 8.2 0.2 3 21 411 429 410 434 0.91

7 12 9.1e-05 0.011 17.3 1.4 3 23 446 467 446 467 0.98

8 12 0.065 8.2 8.3 0.2 2 23 487 509 487 509 0.97

9 12 5e-06 0.00062 21.3 0.5 1 23 520 542 520 542 0.99

10 12 1.3e-06 0.00016 23.2 1.3 1 23 548 570 548 570 0.99

11 12 0.0001 0.013 17.1 1.9 1 23 576 598 576 598 0.97

12 12 3.7e-05 0.0046 18.5 0.1 1 23 604 627 604 627 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00019	0.024	16.3	1.2	1	23	260	282	260	282	0.98
2	12	6.8e-05	0.0086	17.7	1.7	2	23	290	311	289	311	0.96
3	12	0.4	51	5.8	0.9	1	23	315	337	315	337	0.98
4	12	0.00033	0.041	15.5	1.2	1	23	342	365	342	365	0.98
5	12	0.0039	0.49	12.2	0.8	1	23	369	392	369	392	0.94
6	12	0.069	8.6	8.2	0.2	3	21	411	429	410	434	0.91
7	12	9.1e-05	0.011	17.3	1.4	3	23	446	467	446	467	0.98
8	12	0.065	8.2	8.3	0.2	2	23	487	509	487	509	0.97
9	12	5e-06	0.00062	21.3	0.5	1	23	520	542	520	542	0.99
10	12	1.3e-06	0.00016	23.2	1.3	1	23	548	570	548	570	0.99
11	12	0.0001	0.013	17.1	1.9	1	23	576	598	576	598	0.97
12	12	3.7e-05	0.0046	18.5	0.1	1	23	604	627	604	627	0.97

Sequence Information

Coding Sequence: atgaatgatatAAGAGTGTGTAGAACATGCCTATCATTAGATGGAaaagtagtaaatttaaattcgcAGCCATTACATAATTACTATCAACTTTTAATGGGAAAATCTgtATTCTGGGATCCCATACCGGTGACAATTTGTATAAAATGCACCGCCATGTTTATGAAGTTCAGCAAGTTCCGTGAACAATGCATCAATAGTGAGGGCTTACTAAATGCTCTTGTGTGTTCCAATGTGAAGGTAACAGCCAAAGATATTGAGAACAACAGAAGTAGTTTATACCTATCTTTCAATCTCAATGTAAAAACACTGGAAAGTGTAGACATTGCATCTAATTCTGATGATATTGATATGGAAGCCAAGATCGAACCACATGTGGATATCAAAGTTGAGACCGATTTGGACGACTATTATCCTTTATCTAGTGATGATGAGCCACTGTCGTTACATAGAAGCTTAAAGGAAGAACAAGAaagtaaaaaggaaaaaaagaaaaagaagaaaagtGTAACAAGACGAGAGATCCCTctGGTGACAGTTGATTCTAGTCCACTCGAAATACTGGGGACCGGAAAACTAAAGCGTGGAAGGCCAAAGAAACCTAAAGAGGAATCGGAACCCAAAAAACCTGTGGTTAGACGTACCCAGAATACAGGGGGAGTGTGTAACGATGATATGGACTTGGAGACATTCTGCACCATTGTGAAATTGTCGCTCGAGGAGCAAATAGCTGAGGTATCCAAGCGTCAGAACTCGTCGAACTACAAGAACGCGCTGTACCAGTGCGAACTCTGCTACAAGGGGTTCATAGACAGCGACGCGTGGAAACATCACCTCAGTAAACACAGCCCGAGTGCAGGTGAGATGGAGTGTCCGGTGTGCAAGATAAGGTTCAGGACGAAACGGACGCTTCAGAAACACACCTCCAACCACGAGAAAAAGTACGAGTGTAAGGCCTGCTCGTACGTCTCACAGACCACGACCCAAGCTAAGCAGCACCAGCGGTGGCATAAGGGCGTGACATACAAGTGTCAGTACTGCGATGAGGTTTCCACAAAATGGACATCCTATCTAAGCCACGTGCGTATGAAGCATCCATCAGAGCACATCTGCGCGACCTGCGGCTACTCCTTCGTCAGTCGCCTGGGCCTCACCATGCACAGGACCATGATGCACAAGAACCAGAAGGACCAGGAGAAGAAAGAGACAGACAACGCTGACGCGAGATACTGCGCGGAGTGCGACGTGCAGTTCGACACGACGCAGGCGTGGAAGCGGCACATGGTCACGTCGATTAAACACACACAGAGCCGGGACTTCAAACTAGTTAACGGGTGCCGAGTGTGCGGCGAGCGGTTCGCGGACAGCGAGCAGTTGCGCGTCCATCACCGGCGGTCGCACGCGCGCGCCCGTCCCAAGAACTACGGCAAGCCGCGCAACCAGCGCACCTGGCCCGCCAAGTGCACATATTGTCCAGAAGAGATACCGAACGCGCGCGAGTACTGGACCCACTTCCGTCGCGAGCACCCCGACAAGAACTACCCGATACCGAAGGACTACGTCTGCGATATTTGCGGGAAGAGCTTCCGGGGTAATGCGTTCCTCGTCTACCACAAACGCACGCACTCGGGCGAGCGCGGGTTCAAATGCCCGCTATGTCCGAAGGCGTTCTTCAACCGCTACAACCTACAGATGCACGAGAAAACTCACTCGGAGAATAGACCACATCCTTGTTCGGTTTGCTTTAAAGCATTCAAGAGTAAAGGCGCCCTGGATAGACATTTTAGAaGCCACACCGGCGAGAAACCGTACGCCTGCGAAGTCTGTGGCAAGGCGTTCGCGCAGTCCAACAGCAGGAAACTACACGTGAGGACCGTGCACCTGAAACAGCCCTCCCCGTACCTCAGCCGCAGCCGCCAGGAGCGCCGCaagtgcgccgccgccgcgctgcAGCACAAGGAAGCGCACTACTGA
Protein Sequence: MNDIRVCRTCLSLDGKVVNLNSQPLHNYYQLLMGKSVFWDPIPVTICIKCTAMFMKFSKFREQCINSEGLLNALVCSNVKVTAKDIENNRSSLYLSFNLNVKTLESVDIASNSDDIDMEAKIEPHVDIKVETDLDDYYPLSSDDEPLSLHRSLKEEQESKKEKKKKKKSVTRREIPLVTVDSSPLEILGTGKLKRGRPKKPKEESEPKKPVVRRTQNTGGVCNDDMDLETFCTIVKLSLEEQIAEVSKRQNSSNYKNALYQCELCYKGFIDSDAWKHHLSKHSPSAGEMECPVCKIRFRTKRTLQKHTSNHEKKYECKACSYVSQTTTQAKQHQRWHKGVTYKCQYCDEVSTKWTSYLSHVRMKHPSEHICATCGYSFVSRLGLTMHRTMMHKNQKDQEKKETDNADARYCAECDVQFDTTQAWKRHMVTSIKHTQSRDFKLVNGCRVCGERFADSEQLRVHHRRSHARARPKNYGKPRNQRTWPAKCTYCPEEIPNAREYWTHFRREHPDKNYPIPKDYVCDICGKSFRGNAFLVYHKRTHSGERGFKCPLCPKAFFNRYNLQMHEKTHSENRPHPCSVCFKAFKSKGALDRHFRSHTGEKPYACEVCGKAFAQSNSRKLHVRTVHLKQPSPYLSRSRQERRKCAAAALQHKEAHY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01217718;
90% Identity: iTF_00289145;
80% Identity: -