Basic Information

Gene Symbol
-
Assembly
GCA_963931995.1
Location
OZ008370.1:225424272-225429716[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 4.4 9.5e+02 2.8 0.6 1 23 251 274 251 274 0.92
2 9 2.7e-05 0.0059 19.2 1.9 1 23 281 304 281 304 0.98
3 9 3e-05 0.0064 19.1 1.7 1 23 312 335 312 335 0.97
4 9 0.039 8.5 9.3 0.2 3 23 347 368 345 368 0.94
5 9 1.1e-05 0.0024 20.4 1.4 2 23 375 397 374 397 0.94
6 9 1e-06 0.00022 23.7 1.6 1 23 405 427 405 427 0.99
7 9 0.083 18 8.2 0.3 2 23 435 459 434 459 0.94
8 9 7.4e-05 0.016 17.9 0.3 1 23 465 487 465 487 0.97
9 9 1e-05 0.0022 20.6 1.0 1 23 493 515 493 515 0.98

Sequence Information

Coding Sequence
atgttttccttGTATAATCTGAAATATCACTGTCGAACGTGTTTAATAAAACTCGACTCATCAAATGGTAGCAAGGAAACAaagaaattgttttccattagcAGCTTCCCCGATGTAGAACATCTTATGCGCGTGTGTTTGGTCCAGGACTCATCCGATATTAAGGATGCTGATTGTCTGGTTAATCATATGCCAAATCTTTGCTGtttatgttttgaaaaatggCAAGATTTTACAAGACACTATCAGTTGGCTGTGCAGAATGATAAAAagttacgacaaatcctggatgACGACGTATCCGCCAAATTTGCTTTGGGAACACATACAAAGGAGGGCATGCCAAATCAGGTGTTCATAGAAACAGGGAAAAATAAAGACTTCTGTGAGATCGAGAAATACGATACCGTTTCACCTTTTTACCGAACCAGTCGATTAAGTACACCAACCGGGTATCTTCAACATGAGGATAACGAAAACGCTTTAGATTACACAACGCAAAGTGAAAGTCCACCTGTAACACCAAAATCAATAAATTCCAGTGATGAAAACGCCTCAATAGATGACTTCAAAGAGGCAACACACAACTCTAAACAGAAAAGAGTTCAATCCAAAAAATTAACATCAATTCGTTCGAATGTCTGTAAAGGCAAAAGAATCCGTATTACAACAAAACAGTTCAAGGATTCAGATGATGACGACCCAACTGATACGGCAAAGTCTGTGAAAACTCCTACCAAGAAAGCACACTATCGTTGTGTACCCTGTAAGAAGTATTTCTATGAAATACGTAAGTACGAAGCTCATGTAAAGGAAGTTCACGAAGGTGCCAAAAAACCATATCAATGCAAGGATTGCGATAAAGCTTATAAATTTCACAAAACACTTATCGACCACATAGCCACTAATCATTCGGATAAACCATTGGAAACGTACAAAtgtgaaatatgtaataatatgttTAAAACTCAAATAACCCTCAAAACACATATTCAAAACAAACATCCCGAATCTGATGCCGAAAGCCGGCGTATTATCTGTGATCAATGTGGATTTTTGGCTGTCAATCAGATCTCGCTCAAAAAGCATATAAAAAATAGACACACCGAAGCTGATGAGCTCCAGTGTGACGAATGTCCCAAAGTATTTAAAAATCAGTATTActtaaaatatcacaaaatgaATTTTCACAATCCCATGAATATAAAACCTTTTCAGTGCGGCAAATGTGATATGGCTTTTACGCGGCAATCTTTATTGAATACTCACAAACGTAGCCATCTTGACATCACCGAGCGTATAAAATGTGATTTTGAGGGATGTGATGTACGTTTCTTACAGCAGGCTGAAAAAAGACGTCACATGCGTTTGGTCCACCTAAAGGTGAAGCAATATGTTTGTGACATTTGTGGAGCGGCATTTGGGACTAAGCCAACATTGCGACACCATCgctacatacatacaaatgagAAACCTTACAAATGTAATGTTTGTGGACAAGGATTTCGACAGCGTTCGGCAATGAAGACACATAGCAAGATACATATTGGCAAATCGGTGGTGGTTGAGAGGAAATCAGAAAGTTCAATTGGTGTATAA
Protein Sequence
MFSLYNLKYHCRTCLIKLDSSNGSKETKKLFSISSFPDVEHLMRVCLVQDSSDIKDADCLVNHMPNLCCLCFEKWQDFTRHYQLAVQNDKKLRQILDDDVSAKFALGTHTKEGMPNQVFIETGKNKDFCEIEKYDTVSPFYRTSRLSTPTGYLQHEDNENALDYTTQSESPPVTPKSINSSDENASIDDFKEATHNSKQKRVQSKKLTSIRSNVCKGKRIRITTKQFKDSDDDDPTDTAKSVKTPTKKAHYRCVPCKKYFYEIRKYEAHVKEVHEGAKKPYQCKDCDKAYKFHKTLIDHIATNHSDKPLETYKCEICNNMFKTQITLKTHIQNKHPESDAESRRIICDQCGFLAVNQISLKKHIKNRHTEADELQCDECPKVFKNQYYLKYHKMNFHNPMNIKPFQCGKCDMAFTRQSLLNTHKRSHLDITERIKCDFEGCDVRFLQQAEKRRHMRLVHLKVKQYVCDICGAAFGTKPTLRHHRYIHTNEKPYKCNVCGQGFRQRSAMKTHSKIHIGKSVVVERKSESSIGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01175644;
90% Identity
-
80% Identity
-