Basic Information

Gene Symbol
-
Assembly
GCA_963931995.1
Location
OZ008370.1:69862126-69864075[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.01 2.3 11.1 0.2 3 23 324 345 322 345 0.96
2 10 0.091 20 8.1 0.2 6 23 354 371 354 371 0.98
3 10 0.0001 0.022 17.4 2.0 1 23 377 400 377 400 0.96
4 10 3.1e-06 0.00068 22.2 0.6 1 23 406 428 406 428 0.98
5 10 0.00024 0.052 16.3 0.8 1 23 435 458 435 458 0.97
6 10 0.078 17 8.3 0.2 2 23 463 484 463 484 0.95
7 10 0.0042 0.91 12.3 0.0 1 23 492 515 492 515 0.91
8 10 0.00035 0.076 15.7 0.3 1 23 522 545 522 545 0.98
9 10 1.4e-06 0.00031 23.3 0.6 1 23 551 573 551 573 0.99
10 10 0.0002 0.044 16.5 4.9 1 23 579 602 579 602 0.98

Sequence Information

Coding Sequence
ATGAGGGCGAAAAATATTTGCTGCTTATGTCTCTTGGCATCTAACagttataaattaatacaaaatgaaAGAGGTGATAGTACCGAGATTTATGATGTCACGGTGAAATATTTTGATCCAATGATTCTTACTGAAGAGCAAAGCTGCAAGTCCATTTCGTCAAGAGTAATATGCTGTGGATGTTGGTCCCACATCTATGATTTCCACGAATTCCAACAAAGAGTCCTTAAGTCACGTACATTGCTATATGAGACAAATGATAGGAAAATGGTTGCTCATTTTATGAAGGCTTTAACAGAAATACAGGTGGAAAATAAGGGTTTATTAAGTGATGAAAGCATGTCAGAGAGGGAGGCAGTTAATTGTGCATCAGATCAGGATGATGAGATACCATTGATAAGTTTATTTCAAGAAACCCGTGTAAAACAACCACCTGTCACGCTAAAGATTGACACAATTCAGTTGGATGATAGTGCTATTAAATCCTATAACGCCAGTACGCACATTGCTAAAGACGAGCCACAAATTGTGTCATGTCCTAGTTCAGTTAATCAAAAGAACAGctttaacaatgaaatattacGTCCCCAACTTTCAATAACCGATTTCAGTGCAACTACTGTAAAGATCGAAGATGGATCCGAAGCTAATTacgaaatattttctgaaacaatAAAAATGCAAGAATTGTCCTCAGAGGAAATCCAGACCGACGTGCTACGCGAAAATGACCGATGTATTAgcaaaaatatcaaatcaaaacGGAGAGCCAGGATTACAAAAAAGTGGTTAAACGAGCAACAAATCTTAGCTTCCCCCTCTAATAGTCGTGGGAAGCTGTTTGGATCtgtaagaaaaaagaataaaacaaaattacgCAGTAAGGGAAAGAACTCAGCGTGTGGCAAACTTAAAGAGAAGTGCAGAGAAAATGACATTTTTATATCCAAATGGAAACCAATATTGGACTGCGATTTGTGTCCAACAACCGTTTCTAATTTTGATGAAATGCGAAACCACTTTCGAACGGCGCACAATGTAAAACCATATATAAAGTGCTGCGAGCGCAAATTCTATCGTCGATATGTCCTAATAGACCATATACGACTTCATGTAAATCCAGAAACACATAAATGTGATATTTGCGGAAAACTCAGTACGAACAAGTATAATCTGAAACTTCACAAGCAAGTGGTGCACAGCGAATCCAAACAGTTTGAATGTGAAATCTGCAATAGATCGTTTAACCAAAAACCGACATTAGATCGACATCTCTTAACGCACATCAAAGGCGATAAAAAGTTCTTTTGCAAAGAATGTGATAAAGGTTACTTCGTAGAAGACCAGCTAAAATATCATATAAAGACAGTGCACAACGTTGATCGTGTATGTGACCAATGTGGTAAAACTATTCATGGTGTAGCCGCACTTAAAAATCATCTAATGGAACATGCTGGAATCGCTAGGCGCAAATTTCCGTGCGACATATGTGGCGCTGAACTTGTCACAAATTATGGCCTTCGACGCCATAAGGCTGCTTATCATCACGACGGTTCTACAGCCTACGTTTGTGGCGTTTGTGGTAAAGTCGCTTCAAGTCATAATGCTTTGATGTCGCATAAGAAAACTGTCCATGAAAACGGCAGAAGTTTTAAGTGTACATATTGTGATAAAGCTTTCAAGCGAGCTACAGTTTTGCGAGAACATATTGCTACACATACTGGCATTGACTTGTATGAATGTCCACATTGTCCTCAAACGTTCAAAGTTAGCGCAAATATGCACCATCATCGTAAAAGAGCGCATCCTGTTGAATGGGAAGAAGGTAGGAAGAATCGTACAGCATTGCCAAAAGTGGATATACAGCAAGTTACAAATCAAGTTGTATTGTAA
Protein Sequence
MRAKNICCLCLLASNSYKLIQNERGDSTEIYDVTVKYFDPMILTEEQSCKSISSRVICCGCWSHIYDFHEFQQRVLKSRTLLYETNDRKMVAHFMKALTEIQVENKGLLSDESMSEREAVNCASDQDDEIPLISLFQETRVKQPPVTLKIDTIQLDDSAIKSYNASTHIAKDEPQIVSCPSSVNQKNSFNNEILRPQLSITDFSATTVKIEDGSEANYEIFSETIKMQELSSEEIQTDVLRENDRCISKNIKSKRRARITKKWLNEQQILASPSNSRGKLFGSVRKKNKTKLRSKGKNSACGKLKEKCRENDIFISKWKPILDCDLCPTTVSNFDEMRNHFRTAHNVKPYIKCCERKFYRRYVLIDHIRLHVNPETHKCDICGKLSTNKYNLKLHKQVVHSESKQFECEICNRSFNQKPTLDRHLLTHIKGDKKFFCKECDKGYFVEDQLKYHIKTVHNVDRVCDQCGKTIHGVAALKNHLMEHAGIARRKFPCDICGAELVTNYGLRRHKAAYHHDGSTAYVCGVCGKVASSHNALMSHKKTVHENGRSFKCTYCDKAFKRATVLREHIATHTGIDLYECPHCPQTFKVSANMHHHRKRAHPVEWEEGRKNRTALPKVDIQQVTNQVVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-