Basic Information

Gene Symbol
-
Assembly
GCA_963931995.1
Location
OZ008370.1:213909047-213915032[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 7.8 1.7e+03 2.0 0.0 2 23 238 259 237 259 0.94
2 18 1 2.2e+02 4.8 0.3 2 23 308 330 307 330 0.94
3 18 0.0014 0.31 13.8 3.1 2 23 386 408 385 408 0.94
4 18 0.005 1.1 12.1 2.9 2 23 425 447 424 447 0.94
5 18 0.029 6.3 9.7 3.1 2 23 472 492 472 492 0.96
6 18 0.00015 0.032 16.9 1.3 3 23 508 528 507 528 0.98
7 18 0.00048 0.1 15.3 0.6 1 23 537 560 537 560 0.96
8 18 9.1e-05 0.02 17.6 1.3 1 23 565 587 565 587 0.97
9 18 1.9e-06 0.0004 22.9 1.4 2 23 593 614 592 614 0.97
10 18 0.0039 0.85 12.4 2.4 1 23 620 642 620 642 0.97
11 18 0.061 13 8.7 5.7 1 23 647 669 647 669 0.95
12 18 0.6 1.3e+02 5.6 2.5 1 23 674 698 674 699 0.96
13 18 0.0023 0.5 13.1 0.5 1 19 783 801 783 806 0.91
14 18 0.013 2.9 10.8 0.4 1 23 815 837 815 837 0.98
15 18 1.3e-05 0.0029 20.2 0.3 1 23 842 864 842 864 0.99
16 18 0.0028 0.6 12.9 2.2 1 23 870 892 870 892 0.98
17 18 0.012 2.5 11.0 2.6 1 23 897 919 897 919 0.96
18 18 0.47 1e+02 5.9 0.3 1 23 924 948 924 948 0.95

Sequence Information

Coding Sequence
ATGGATAAGCAACGTTGCCGTTGTTGTTCAACCACAAAGTCAGACCATTACTTCGACCTATTCCAAAAGTGCAAAACCAGTAGAACGTATGCTGAAAACATTCATAATATTGCAGAAGTGGACGTGGAGGTCTGCGATGAATTACCACAATTTGCTTGTGGCGATTGTTTTAGTGAACTGCAGAATATTATCGAGTTTGCTCTAATTATACGACAGACCGATGATAATCTAAGAATGGAACTGCAGCAACAACGTCATACATCAGTTGATGGGAAGTTAGTGGAGAGTGATCATGTATTCGAAGAAGATTGTGTTGCGGCTGACGAAGACCAAGAAGATATGCAAGTGTGTATATTGGAAGAGGAGGTGTTAGACGTCGAAGAGACCTTGCATCAGCAAGCAGAAATGACAATTGTAGAGGAATATGTTAAGGATGAGAATGTCGAAGATCTTCAAATGGTTGAAGAAATTCTTGAATTCGACGAGGAAGTTCCTAATGATTCAATTGAACACATATTGCCAAAAGAAAACGATCCACTTCAAGAGCTAGCGCAAGTTGCGGCAACACAAGAAAATGTGCATGTAGACCAAACTCAAGATCCCGACAGCCACCAAGAATGCTATTATACCGAAGATGAATGTGACGATGAGTATCTTATAGAATATAATCCAGCTGATGAGTCACATTGTGGTTTTAAGCCGCTTAAATGGAAAtgtgtagaatgtaaaataatacTACGTGGTGATGTTTCCTATGAGGGCCATATGAATATCCACAAAAAAATTAGACCTCACAAATGTCCACAATGCCGTTGTCAATTCAGATGCCGGAAGTCCTTAAAGAAACACAAACAGACTAGGCACAGTAATGCATTTCCTGCGCATAATACTAAGATAGAAGAAATAACTATAGTCCAAATGAAATGTTTAGACTGCAATGTGGAATGTCAAACAGAAATAGATTTACTTAAGCACGAACTAATAGCTCACAATAAGCATTCGCATACAACATCCTGTCCTTTATGTCCTGACGTCATTGTAGATAATTTATTGAATCATATTCAAAGTGTCCACATGGATCGGTCATCTCATCCCTACGATGAGGTTACCGAAACATTGTTGGAACCATCCCCATCCTCGGCAATAACTTTCTTACATTGTGGTATATGTTCAAAAGCATACAGTTCAAAATCTGCGTTAAATGACCATCGGAAGCTCTGCCATGCCGAAACCATGTTGGAACCATCCCCATCCTCGGCAAGAACTTTCTTACATTGTGGTATATGTTCAAAAGCATACAGTTCACAAACTGCGTTAAATGATCATCGGAAGCTCTGCCATGTATTAGATGAACCGGTTGCTACCGTTATTGATGAATATGATTGTTATGTTAATATGCTGGATTCAATAGCTCAATGTGAGATatgtaaaaagaaattaaaaaggaaaaatcTTAACAAACACATGACATTGCATGAACGAAAAGCAAAAGAGGCCGTGGAGCAGCAACCTAAACTGTTATGTGCCTATTGTCCACGTGAATTCAAAAATTCCAAGACCTTGAAACAACACGAAAAAACGCATCAGGGAGAAACTGCCGATACTGTTTACGTATGTGGTGATTGTGATCGTCAGTATAATTCATATTACCTACTCGAAACTCATCGCAAGCAGGCACACAAAGACCGTGAACATGTCTGCTCCATATGCGGCAATGCGTTCAAGTTAAAGAACCAACTCATGAATCACATGAAACTGCATTTGGAAAAGAATATACAGTGTCCACATTGTGACAAAAAGTATGCTAGGCAGTTTGATTTAAATGTTCATCTTAGATCGCATACTGGAGAGCTGCCATTTGCCTGTCATTTGTGTGATAAACGCTTTGCTATAAAGGTACGACTCACTTATCACCTGCAAAAGCACTTTGGGGTCAAGCATCAATGCAAATGGTGTCATGCGGAATTTAATTCGAAACAGAAGCTTAAGGCTCACTCATTTAAACATACTGGTATGCCGTATCGTTGTGAGCTGTGCGATGACCATGGATTTGCCAATAGGGTGGTATTTAAACGCCATTTGAATCGTGTTCATCATGCATCCATGTCCGACGAGGCTTTAAATGAAATGTTCCAACGTAATACTGGAAAAACCATTAAAATAAAGCAAGTCATCGACCCGTACATGGTACCTAGTCCCGATGATGTTGAAATCGAGGCGGAAATTGTTGAAGAAAGTCCTGTGCTTATAACTCAAACATTTTTAAGCGATATTCAATTAACAAACCATGTCACTTCCACGCATTACACAACATCAACAGCAGAATCATTTGTGGTGCATCTACAGTACGAATGTACAAAATGCGACGAAGCTTTTGAGGACAGCCAGTTGCTAAAAGAGCATGATCAAAAGCAACATTATTTCAAAGAACCTACGACAAAGTACGTTTGTAAGATATGTGGCAATTTATTTGGCGGTCATGCCCAATTATCCGCCCATAAACGACTGCATAAAGAGCGACCATTCAAATGTGATCAGTGCGAAAAAGCCTATCCTCGAAAAGTGGAACTTGATATACATATGCGTAGTCATACAGGTGAATTGCCATATGCCTGCCATTTATGTGACAAACGATTTGCAATTAAGGTTAGACTCACATACCATTTGCAAAAGCATGAAGGTGTCAAACATTCCTGTTCCTATTGCTCTGCCGTCTATGATAATCGCAATAAGCTGAAAGCGCACTTATTCAAACACACAGGTATGCCCTATAAATGTGAAATTTGTCCGGGCTTAGGATTTGAAAGAAGATTGCGATTTTCTAACCATATGCAACGAATTCATCAGCGCATTTTAACGGATGATGAGTTAGCGGAAATCTTTGCAAAAAACACTGGAAAAACTGTACGCTTTAAATCTACGATTGGAAAAAACTTATAG
Protein Sequence
MDKQRCRCCSTTKSDHYFDLFQKCKTSRTYAENIHNIAEVDVEVCDELPQFACGDCFSELQNIIEFALIIRQTDDNLRMELQQQRHTSVDGKLVESDHVFEEDCVAADEDQEDMQVCILEEEVLDVEETLHQQAEMTIVEEYVKDENVEDLQMVEEILEFDEEVPNDSIEHILPKENDPLQELAQVAATQENVHVDQTQDPDSHQECYYTEDECDDEYLIEYNPADESHCGFKPLKWKCVECKIILRGDVSYEGHMNIHKKIRPHKCPQCRCQFRCRKSLKKHKQTRHSNAFPAHNTKIEEITIVQMKCLDCNVECQTEIDLLKHELIAHNKHSHTTSCPLCPDVIVDNLLNHIQSVHMDRSSHPYDEVTETLLEPSPSSAITFLHCGICSKAYSSKSALNDHRKLCHAETMLEPSPSSARTFLHCGICSKAYSSQTALNDHRKLCHVLDEPVATVIDEYDCYVNMLDSIAQCEICKKKLKRKNLNKHMTLHERKAKEAVEQQPKLLCAYCPREFKNSKTLKQHEKTHQGETADTVYVCGDCDRQYNSYYLLETHRKQAHKDREHVCSICGNAFKLKNQLMNHMKLHLEKNIQCPHCDKKYARQFDLNVHLRSHTGELPFACHLCDKRFAIKVRLTYHLQKHFGVKHQCKWCHAEFNSKQKLKAHSFKHTGMPYRCELCDDHGFANRVVFKRHLNRVHHASMSDEALNEMFQRNTGKTIKIKQVIDPYMVPSPDDVEIEAEIVEESPVLITQTFLSDIQLTNHVTSTHYTTSTAESFVVHLQYECTKCDEAFEDSQLLKEHDQKQHYFKEPTTKYVCKICGNLFGGHAQLSAHKRLHKERPFKCDQCEKAYPRKVELDIHMRSHTGELPYACHLCDKRFAIKVRLTYHLQKHEGVKHSCSYCSAVYDNRNKLKAHLFKHTGMPYKCEICPGLGFERRLRFSNHMQRIHQRILTDDELAEIFAKNTGKTVRFKSTIGKNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-