Basic Information

Gene Symbol
-
Assembly
GCA_951640565.1
Location
OX621218.1:2903491-2914344[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 27 0.0078 0.7 11.3 1.3 1 23 10 33 10 33 0.94
2 27 0.079 7.2 8.1 0.2 2 23 127 149 126 149 0.93
3 27 0.22 20 6.7 0.2 1 23 170 192 170 192 0.85
4 27 0.0012 0.11 13.8 0.0 1 23 196 218 196 218 0.97
5 27 0.0068 0.61 11.5 2.3 2 23 226 248 225 248 0.95
6 27 0.0019 0.18 13.2 0.6 2 23 254 276 253 276 0.95
7 27 0.33 30 6.2 0.8 3 23 324 344 322 344 0.96
8 27 7.8 7.1e+02 1.8 0.3 2 23 371 393 370 393 0.89
9 27 0.00051 0.046 15.0 0.6 1 23 414 436 414 436 0.96
10 27 0.0022 0.2 13.0 0.2 1 23 440 463 440 463 0.96
11 27 0.077 6.9 8.2 0.2 1 23 504 527 504 527 0.96
12 27 0.3 27 6.3 0.2 2 23 551 573 550 573 0.93
13 27 0.0034 0.3 12.4 0.3 1 23 594 616 594 616 0.97
14 27 0.39 35 5.9 2.9 2 19 621 638 620 642 0.89
15 27 0.0021 0.19 13.1 1.1 1 23 650 673 650 673 0.97
16 27 0.37 34 6.0 4.6 1 23 678 701 678 701 0.97
17 27 0.059 5.4 8.5 1.0 1 23 707 730 707 730 0.96
18 27 0.0011 0.1 13.9 3.3 1 23 736 758 736 758 0.98
19 27 4.4 4e+02 2.6 1.0 1 20 822 841 822 845 0.83
20 27 0.011 1 10.8 4.4 1 23 912 934 912 934 0.97
21 27 0.00031 0.028 15.7 0.9 1 23 938 960 938 960 0.98
22 27 0.0094 0.85 11.0 0.5 1 23 965 988 965 988 0.95
23 27 0.00011 0.0096 17.2 2.1 1 23 994 1017 994 1017 0.98
24 27 0.04 3.7 9.0 1.3 1 23 1024 1047 1024 1047 0.95
25 27 0.0012 0.11 13.8 1.5 1 23 1053 1075 1053 1075 0.95
26 27 1.4e-06 0.00013 23.0 1.0 1 23 1081 1103 1081 1103 0.99
27 27 5.7e-07 5.2e-05 24.3 2.6 1 23 1109 1131 1109 1132 0.96

Sequence Information

Coding Sequence
ATGATATCCGAGCACGGCATCTTCGCTTACAAATGCCCATACTGCACGGAGACTTTCAAAGAATATCGAGCAAGAATAACACATTTAAACGAGTTCCATGATAAGAACATAAACTATCCTTGCAGAAACATCACTATAAAATGGAGTCTACAACTCGGTGATTTTGGCGACGCGCGAGACAACGCGGCCATTATCTTGGAGTGTTCCAACGCGTGTCCcttcaaatttcatcgaaatgcTTTTACTTGTGCATACTGTCCCTTCACCTCGCCAGAGTTCGGTCCTATCAAAGAGCATACTAAAGAGCACAAAGATAGAGCTAAGGCTATTCGAAATATTAGAGCCTCTGCAGTATGCAAAGCAGAGGTCACTGATCTGAAATGTGAACTCTGTCAGAAAAGCATGAAAGACATATCAACGCTGTTTGAACACTTGATTGAAGTTCACGGCAAGCCGTTGATAAGAAAACACAGAACTGGCATCTTGCCTTACCTGTTAAGCGACGGGTTCACTTGCGCCGACTGCGGCCTTACTTTTGATTGGTTTTGGAAATTAAATCAACATGTGGATGAGCATTACCCCTATTTCGTTTGTTCGGAATGTGGACTTGCATTCTCGAGCGCGATAAAGTTAAATGGTCATTCTGCTACTCACCAAAAGAGGACATCTCAGTTAAAATGTTCTCAATGCGATGCAACCTTTACGAAAGAATCTTCGAAACGTAAACATTTAAGTTCTAAGCATAACATCTTCTCCAATAAATGTCCATATTGCCCCGAGAAGTTCAAACGATATGAAGATAGAATAACACATTTAAACGAGTTCCATGATAAGAACATAAACTATCCTTGCAaACCTGGCAAAAGGAGGCTGAAAATCGGAGACTATCACGACGCACGAGACAATGCGGCCATAATCCTAGAGTGTTCCAACGTCTGCCCCTTTAAGTGGCGCAAAAACGTTTTCGGTTGCTCGTACTGCTCCTTCACTTCACCAGATTTTGGTACATTTAAAAATCATATGACAGGCCATCCCCTGAAAACTGGCAGAATCGAGACTCTCCGCAACTCTCGACCTGCGGACACGGTTAAAGCAGATGTTGTTAATTTGAGATGCGAACTTTGCCAAGAACATATGAAAGACATAGCAACACTAATGGATCACCTTATTGATAAACACAATAAGCCTATAGTCAAAAAATATGATTCGGGTGTAGTACCGTATCTGTTAGATAAAGGATTTACGTGTGCCTATTGTGGCCAAACGTTCGACCGGTTCATAACGTTAAACACTCACGTGATTCAGCACAAGCTTAACTTTGCCTGCTCTCAATGTGGACAGTATATCTCCAGTCCTGAAGGTTTAAGGAAGCATATCCTTAGGCGTCATGTGAAAACTCCGAAAACAGATTTCCGACCAAAGTTGAGCGACTATAACGACGCTAGACACAACGCCTCCATTATTCTAGAATGTTCCAATGTTAGTCCCTTTAAATGGCATCGAAATGTGTTCAGGTGTGGCTACTGCGAATTCACTTCCGCAGATTTTGCTCCATTAAAGGCACACATACACGTGGCGCATCCGAAAAGGCTCGAAGCCCTTCACTACTCCCGTCCAACTGAAATATTCAAGGCTGATGTTACTGATCTCAAATGCCAACTGTGTGATCAAGCGATTAAGGATATGAAAACACTGATTGACCACTTAAGTGAAACCCACGAAAAGTCGATAAAGAAACATTACGGCCCCGGCATCGTTCCTTACTTGCTGAACGACGGATTCACGTGCGCCGACTGCGGCCTACAGTTCGATCGTTTCATGAAACTAAACATACACGTGAATGAGCACTACCCTAATTGCATTTGTTCGCAATGCGGGCAGGCCTTCTCCAGCGTGAATCGGCTTAGAGCGCATTGCGAACAACATAAAAAGAAGACTACTGCACAGTTCAAATGCTCCGCTTGCGGAGAGATCTTCACCTCAAGATTTGCTAAACAAAAACATATGGAGTCTAAGCACGACATCCTCCCCCACAAATGTCCGTATTGCAGTGACGCTTTCAAATCCTACGCTCACAGATTGCAGCATTTGAACAAGTATCACGACAAGAAGATAGAGTACCCTTGCCGTATGTGTTCGGCCGTTTTCAAAACTGCTGGCAAACGGGCCGACCATATGCAACACTTTCATTTGAGGGATAAGCAGTATTCTTGCTCTGTTTGCGACTATCTGTGTACGAGCGTGACTCAGTTGAAGAAGCATATGATGAAGCACGGTGGCGAGAGAAAAAAAAAGGAAGAAATACAGATAAAACACGAAGTGGAGTCAGACTCAGAGAATATTGGAGCCCCGCTCGTAGAGGCCTCAAAAGACGGAGTTCAGAGGCGAGCAGCCTTCCGGAGTAACATTACCACAATCATAGAAACGTGCACAGCGTACCCGTTCAAATACAGGAAGGGCACGTATCTCTGCTTCTACTGCAAGACTACCTTCCTCGAGCCGGAGAAGCTACGAGAACACAACACCTTGCAGCATTCAGAGTCGAAGCAACTGCTAAAGCCGAGAAAGTACGAACCGTTGAAGATGGACTTTTCTAACACGACGTGCAGACTCTGCCGAGTCGACATCGACGATTACGCCACGTTGAAAGCTCATCTAACAGCTGAGCACGGAAAGATCATCGACTGCACGTGGGGAGACAGCGTGCTCCCGTACAAGCTGAGCAAAGAGGAACACCGCTGTCAGATCTGTGGCAAAAGATACGAGATGTTTCTCAGTCTGCATAAACACATGAATGAGCATTACGAACACTACATATGCGAGACTTGCGGAAAAAGGTTCGCCACGTCTCAGAGGATGGTCAATCACTCGCGCACTCACGAGAGAGGAGTATTTCCGTGCAAGCACTGTACTGACTCCTTCCCATCTTACTCCGCTTTGTACGCCCATGTCGCTAAGGTTCATAAGTTGAACAAGAGGTACAAGTGTCCTATATGTGACGAGAAGTTCGCCTCCTACAAGCATAGGTTAAAGCATCTCAACACAATTCACGGGGAAAAGACGGCCGTGTTTCCCTGTCCGTCTTGCCCGAAAGTCTTCGACCTTTGCAGTCGGAGAACTGCGCATATAAGGTTCCAGCATCTCCAAGAACGGAATCATATATGCTCCGTTTGTGGTATGAAGTTCTTTACGAACTATGAGCTGCAAGAACACTCGATCAAGCACGGCGGTGAGAGGATATATCAGTGTGATGTATGCAAAAAGTCATACGCTAGGTTAAAGACTCTCAGGGAACATATGAGGATCCACAACAATGATAGGCGGTTTGTCTGTCCGGTTTGCGGACAGTCGTTTATTCAGAACTGTAGCTTGAAACAACACATGAGAGTGCATCACCCGACGCATTTGAAGgatgttttttaa
Protein Sequence
MISEHGIFAYKCPYCTETFKEYRARITHLNEFHDKNINYPCRNITIKWSLQLGDFGDARDNAAIILECSNACPFKFHRNAFTCAYCPFTSPEFGPIKEHTKEHKDRAKAIRNIRASAVCKAEVTDLKCELCQKSMKDISTLFEHLIEVHGKPLIRKHRTGILPYLLSDGFTCADCGLTFDWFWKLNQHVDEHYPYFVCSECGLAFSSAIKLNGHSATHQKRTSQLKCSQCDATFTKESSKRKHLSSKHNIFSNKCPYCPEKFKRYEDRITHLNEFHDKNINYPCKPGKRRLKIGDYHDARDNAAIILECSNVCPFKWRKNVFGCSYCSFTSPDFGTFKNHMTGHPLKTGRIETLRNSRPADTVKADVVNLRCELCQEHMKDIATLMDHLIDKHNKPIVKKYDSGVVPYLLDKGFTCAYCGQTFDRFITLNTHVIQHKLNFACSQCGQYISSPEGLRKHILRRHVKTPKTDFRPKLSDYNDARHNASIILECSNVSPFKWHRNVFRCGYCEFTSADFAPLKAHIHVAHPKRLEALHYSRPTEIFKADVTDLKCQLCDQAIKDMKTLIDHLSETHEKSIKKHYGPGIVPYLLNDGFTCADCGLQFDRFMKLNIHVNEHYPNCICSQCGQAFSSVNRLRAHCEQHKKKTTAQFKCSACGEIFTSRFAKQKHMESKHDILPHKCPYCSDAFKSYAHRLQHLNKYHDKKIEYPCRMCSAVFKTAGKRADHMQHFHLRDKQYSCSVCDYLCTSVTQLKKHMMKHGGERKKKEEIQIKHEVESDSENIGAPLVEASKDGVQRRAAFRSNITTIIETCTAYPFKYRKGTYLCFYCKTTFLEPEKLREHNTLQHSESKQLLKPRKYEPLKMDFSNTTCRLCRVDIDDYATLKAHLTAEHGKIIDCTWGDSVLPYKLSKEEHRCQICGKRYEMFLSLHKHMNEHYEHYICETCGKRFATSQRMVNHSRTHERGVFPCKHCTDSFPSYSALYAHVAKVHKLNKRYKCPICDEKFASYKHRLKHLNTIHGEKTAVFPCPSCPKVFDLCSRRTAHIRFQHLQERNHICSVCGMKFFTNYELQEHSIKHGGERIYQCDVCKKSYARLKTLREHMRIHNNDRRFVCPVCGQSFIQNCSLKQHMRVHHPTHLKDVF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-