Basic Information

Insect: Perizoma affinitatum
Gene Symbol: topi_2
Assembly: GCA_961405105.1
Location: OY560208.1:7003238-7012722[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.016 1 10.4 1.7 2 23 71 92 70 92 0.96

2 11 0.013 0.87 10.6 0.5 3 23 100 121 98 121 0.94

3 11 0.19 13 7.0 0.1 2 23 129 151 128 151 0.88

4 11 0.00032 0.021 15.7 4.0 1 23 157 179 157 179 0.97

5 11 1.5e-06 9.7e-05 23.1 2.2 1 23 185 207 185 207 0.96

6 11 0.096 6.2 7.9 1.9 3 19 254 270 253 275 0.91

7 11 0.00022 0.014 16.2 2.2 1 23 565 587 565 587 0.97

8 11 0.00021 0.014 16.3 4.1 1 23 594 617 594 617 0.95

9 11 0.0039 0.25 12.3 2.5 1 23 625 648 625 648 0.95

10 11 2.9e-05 0.0019 19.0 2.9 1 23 654 678 654 678 0.98

11 11 2.1e-05 0.0014 19.5 0.4 1 22 684 705 684 705 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.016	1	10.4	1.7	2	23	71	92	70	92	0.96
2	11	0.013	0.87	10.6	0.5	3	23	100	121	98	121	0.94
3	11	0.19	13	7.0	0.1	2	23	129	151	128	151	0.88
4	11	0.00032	0.021	15.7	4.0	1	23	157	179	157	179	0.97
5	11	1.5e-06	9.7e-05	23.1	2.2	1	23	185	207	185	207	0.96
6	11	0.096	6.2	7.9	1.9	3	19	254	270	253	275	0.91
7	11	0.00022	0.014	16.2	2.2	1	23	565	587	565	587	0.97
8	11	0.00021	0.014	16.3	4.1	1	23	594	617	594	617	0.95
9	11	0.0039	0.25	12.3	2.5	1	23	625	648	625	648	0.95
10	11	2.9e-05	0.0019	19.0	2.9	1	23	654	678	654	678	0.98
11	11	2.1e-05	0.0014	19.5	0.4	1	22	684	705	684	705	0.96

Sequence Information

Coding Sequence: ATGGATTCAAACCTACCCTATTTTAGTTTACCATTTGTAGACACTTCAGACCTAGATTTTGGTAAAATCAGGGACCAGGAGTGTGAGTACGATGACTTAAATCCTACCCTGCCACCCCACGGGTCGCTGCTGGGCGCAGACGATGTATTGGCCCAGTTTCTATCAGATGATCCTTTGGAAGAGCCTGACCTAAATGGTCCCACTACTCTACACTGTGAGATATGTAGGAAGCAGTTTGACAGCGCAAAGAAGTATTATGGACATTTGAGAGTGCATTCAAATGACAATCTTTGGATATGCGaaaaatgtccagaagaAAAGTTCTCAAGCAAGCAACAGCTGATGAAACACAGCCTGACGCACAAGCCTCTGTCAAAGGTGTGGCGATGTCCTCAGTGCGAAATGTCCTTCGAAGCTCTTTGGAGACTGCAACAGCATTTGTTTGCAAAACACTTGGATTATAGGCCACACAAGTGCGACGTGTGTACGAAAACGTTTCACAAACTGTCAGATTTAGACAAGCACATGGATATTCATGaagctaTTAAGAAATATTTGTGTAGTACCTGCAAACGGAGGTTCGCAGACAAGTCTAACTTGAAGCGACATTTGCTGACCCATAGCAGTGAGAAGCCATATTCTTGTATAGGATGCGGCCATTGGTTTAAGCAGATAGCCTCTATGAAACGGCACAGCCAACACTGTCCGTTAGTTCAGAAAAGCTTGAGCGGCATCAAGAAATCTTACCGGAACAACTACTGCCGAGTATGTGGACTTACATTTCAGTACAAGAGCTCTTTACTGGAACACTGTGTCAGGACGCACTCCACCAATCCCCCTGAGCCACCACCCGAACCGCCGAAGGAAGACAAATCACACCAACTCCATGTCGACACAAGCCGAACCGTAGACAAAATTGTCGACGACATCCTGGCAGCTGAAGACGATTACATGACCATGTCGACGCAAAACGATCTCATAAACAACTACCCGACTGAAGAAAACCAGGATAATCTAATGCAGATGGAACTATTAAAAGAAATTAATCAAATACATAACATGCAAATACTGGATGATGAACTATACAACGATATAGATCTGGATACGTTACAGAATATGTGCAATAATATAGACTACGATCGGAACGAGCTGTTCGACCTGAACGACGGCCGAAGCATGGACCATATCATGAACGGAAAGAGTCTAGATCAAGACATAATGAACGCAATAGTCTGTGACATTGATCAAAATAAAGAGGAGCCTTTAAAAGAATTCATTAACCCAGAGATGAATTCAAAAGTGAACGAGTTCTTAGTGAATCCACCGGTTTCTGTGAACGAATGCTCGACTATCTTCGAAAGTgacgttgacttagaagctagTACAAATCTAGCGGCCAACTTGAATCAGTTAATAGGCGAAAATTCAGTTCAGTATATCTCAACGGAACACGACGATACGTTTATAATTAATCTTAATAGCGAGATTGACGCGGAGCAGTTAACAGATATGCTGAATGTAGGTGTTGAGAAACCTATTCCGAAGCCGATCAGAACTGAACCTGATTTCCAGATACAACCTGAGACTACACCTGTTTTGAGCATGGAATTGAATCCATTGAAAACTGCAGAGGAAACTATAAGGGAAGAAAAGATGGAAGTAGATTACAGTAAAGctaaaatgaaaactaagtaTGTCTGTCTGGTATGTAAGAGGATATTTAAAACGAAGCATAATTACATTTCACATAGAGctGTACACGATCCAGATCTGCAGCAGTTTCAGTGTACTGTGTGTTCGGAACGGTTCAGTTACAAGTCCACGCTCAACAAGCATTTTACGAAAAAGCATACACCATCGGTTAAACCTGCGCACCCCTGTTATGTCTGCCATAAGATCTATAATTCATCTTGGCTGCTGAAGCAGCATACGGAGCGTGTCCACGAGTTAATTCAGCCATACAAATGCGACTTCAACGATTGCGGGAAGAAATTCTACAGGAGAAATGACCTGGAAACGCATACCagattcCATACTGGAGAAAGGCCGTTTGTTTGCAAGATCTGTGGCAAAGGATTCAAGGCCGTGTCGCACCTCGCGAGGCATACGAGACGCGTGAATTGTTGCAAACTGTAA
Protein Sequence: MDSNLPYFSLPFVDTSDLDFGKIRDQECEYDDLNPTLPPHGSLLGADDVLAQFLSDDPLEEPDLNGPTTLHCEICRKQFDSAKKYYGHLRVHSNDNLWICEKCPEEKFSSKQQLMKHSLTHKPLSKVWRCPQCEMSFEALWRLQQHLFAKHLDYRPHKCDVCTKTFHKLSDLDKHMDIHEAIKKYLCSTCKRRFADKSNLKRHLLTHSSEKPYSCIGCGHWFKQIASMKRHSQHCPLVQKSLSGIKKSYRNNYCRVCGLTFQYKSSLLEHCVRTHSTNPPEPPPEPPKEDKSHQLHVDTSRTVDKIVDDILAAEDDYMTMSTQNDLINNYPTEENQDNLMQMELLKEINQIHNMQILDDELYNDIDLDTLQNMCNNIDYDRNELFDLNDGRSMDHIMNGKSLDQDIMNAIVCDIDQNKEEPLKEFINPEMNSKVNEFLVNPPVSVNECSTIFESDVDLEASTNLAANLNQLIGENSVQYISTEHDDTFIINLNSEIDAEQLTDMLNVGVEKPIPKPIRTEPDFQIQPETTPVLSMELNPLKTAEETIREEKMEVDYSKAKMKTKYVCLVCKRIFKTKHNYISHRAVHDPDLQQFQCTVCSERFSYKSTLNKHFTKKHTPSVKPAHPCYVCHKIYNSSWLLKQHTERVHELIQPYKCDFNDCGKKFYRRNDLETHTRFHTGERPFVCKICGKGFKAVSHLARHTRRVNCCKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01171712;
90% Identity: iTF_01171712;
80% Identity: -