Paff008358.1
Basic Information
- Insect
- Perizoma affinitatum
- Gene Symbol
- NRG1
- Assembly
- GCA_961405105.1
- Location
- OY560191.1:12789647-12812214[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0011 0.068 14.1 0.1 2 23 263 284 263 284 0.96 2 12 0.37 24 6.1 2.5 1 22 289 310 289 313 0.90 3 12 0.0018 0.12 13.4 1.5 2 23 427 449 426 449 0.93 4 12 0.00053 0.035 15.0 0.0 1 23 455 477 455 477 0.95 5 12 0.026 1.7 9.7 0.1 1 23 486 509 486 509 0.89 6 12 3.7e-06 0.00024 21.8 5.7 1 23 514 536 514 536 0.98 7 12 0.0019 0.12 13.3 5.4 1 23 542 564 542 564 0.97 8 12 2.1e-05 0.0013 19.5 2.9 1 23 570 592 570 592 0.98 9 12 1.7e-07 1.1e-05 26.1 0.6 1 23 598 620 598 620 0.97 10 12 0.0024 0.15 13.0 3.9 1 23 626 648 626 648 0.98 11 12 0.0016 0.1 13.6 1.9 1 23 702 724 702 724 0.98 12 12 6.9e-07 4.5e-05 24.1 2.2 1 23 730 753 730 753 0.96
Sequence Information
- Coding Sequence
- ATGGAAGTCGTCTTGTATAATTCAACTGTTTGTAGATTATGTGGAGAAGAAAATGACAATGgaacatttttatattcaactgaagaaaataatcaaaacatcAGTGATCTAGTGAATGCGTATTTGCCAATCAAGGTTTCTGATGATGGGCAACTGCCGCGAACCATTTGTCCTGGATGCACAATCCAGCTCGAAGCTACGGTAGAATTCATTAACTTGATTGTCACTGGTCAGAAAACAATACGAAGTCTCTACAATAGGGAGAAAGAATACaagaaaaatttaaacaaagCCTCTGGAAATGATACAAATGAGACTATTCATATTGAAGTGGATTCACTTGGAACAAATGGGGTTTATCAAGAGGAGCACCCGATTTCCCTCCAAGTGGCTGGCCTGGACAAACCCAAGCGCAAACGTGGCAGGCCTCCCAAGAAAATAAAACCTCCCGATGAGCTGGCATTGGAAGCAGCCGCCATCCAACAAGAGGTAAAAATCAAGCAGAGAGATGAAGAACCTACCGGCAAGAGACGTCGGAAAACCCCTGAAAGATTCAAGGAGGTTGTACAGGGAAAAGAACTAGACCAGATATTCAAAGAAGAAGGCATGACGGATGGCGAGGTCAGTGAGGATGAGGTCAAACCAGAGAAAATCAAGCCTCCTAAAGAGCAAGTTCTGAAGTCACCGGAAGTAATCGGACACACATCGGTGTCAGGGGAGCTTGTGGTTGTTGTGAAGGGAAATGGAAGAGGCAGGCCTAAAGGGCGCACGAAACAAACGCGTGAGACGTGCGCTATATGCGGCAAGGAGTTCTCTAACGCGGGTCGGTACATGTCTCACATCGCTCAGCACGGACCCGTTCTGTACCAGTGCCAGCAATGCCGACACACCTTCTCCATACGACTCGAATACAACGAACATAAAAGGGAGACGGGACATGAAGGGCTCAATATCCTGCCTGGCAAGGATGAAGATAATATTGACTCTGAGGCTCCCAGCCAAGTTCTAGCAACACCTCCCAACCCCCACCAGCCACCGGCCGAGATATTCGCGACGCCGGAGCCCCCGGCCGTGAAGCTGGATGACGGCATGGCTGCCACGGTGGGGTCCTTGCCGGATCTCAGCGCGCAGCCGGCTGAGCTCATGAACGTGGAGTTTCTTAAACTGCCGGAGTTGCAAGCTGAGGGGAATGAAGATGAGCAGAAGAAAGaaataaataaaactgagtTCAAGGATAGTCTTACTGTGGAAGAGCCAGTGCCAAAGAAATACAAGCTGAAGTGTCCACACTGCGACAAGAAGTACAGCAGCAAGCAGGCCAAGTCTATGCACATCAAGGCGGCACATAAAGGCGAGCGTCCATACATCTGCAACGAATGCGGTGCTTCGTTCGCGTACCCTCGCGCGCTCACCTTGCATGCGCTCGCGCATCGGAGACGGACCACTTCTAAGGGATTCGCTTGTGATCTATGCGGAAAGgtCCTGAATCATCCGTCGTCTGTGGCGTACCACAAGGAGGCGGAGCACGCGAACCAGCGCTACGTCTGCAACAAATGCGGGAAGCACTTCAAGCACAAGCAGCTGCTGCAGCGGCACCAGCTGGTGCACACGCAGAACAGACCTTTCCACTGCAAGACCTGCAACTCGAAATTCAAGACCAAAGCGAACCTGTACAACCATCAAATGCTACACACGGGCGTGAAGAAGTTCTCCTGTGAAGAGTGCAAGCAACGCTTCGCTCACAAGACGAGTCTGACGCTGCATATGCGTTGGCATAGAGGTCAAAAGCCGTTCGCGTGCAAGTACTGCGATAAGGCGTTCACGCAGAAAGGCAACCTGTCCGAGCATCTGCGCATACACACGGGGGAGAAGCCGTTCCAATGCGTGCTCTGCCCGCGTCGGTTCACCACCTCCTCACAGCATCGCCTGCACCTGCGCAGGCACGAACCCAAACAGCACAGGGCATGTCCGCGCGCGTCGGCTACGGAAGCGACTACGAGGAGCATAGTGAGCTCTGACGGTAGCGTCATCCAGCTGACGGTGGGCGGCGGTGACGTCGGTGACGGTGGTGACGTCGGTGACGGCGGTGACGTCGTAACGGGTCACAAGTGCGCGTGGTGCCCGCGCGTCTGCGGCACGCGCTGGACGCTCGCCAAGCACCAGCGGCTGCACACCGGCGAGCGGCCCTTCCAGTGTCCGATCTGCAAGAGATGCTTCGCGGACGCATCCAATCTCAACAAGCATAAGAAGCAAATCCACAAGCAGACCTCTCTCCTGGCGCTGCAGCCACTCCCCCCCGAGTCGGAGACAGAGTGCCACGTAGAGTTGCCGTCGCAGCCGCAGTACGTAGTGCAAACGGAGGAGGACGAGGAGCGTGTCATCTACGTCACTTACGACGTGAACGAGCAGGAGCCAGCCTACGAGATCTTGGAATCCGAACAGGATGATTTCTCTATGGAGGCCCTCTCCCCGAAGGACTGCGAGCTGTACTCCGGCGAGTCGCTGCTATTGCAGCACAAGATGCAGGAAGAACAGGAACACATGTCGGTGACGGACGAACAGGGCAATCCCCTGCACTTCACAATGCAGGACGGCACGCGGCTCGCGATAACCTCTCTCGATGGACAGTCTTTGCAGGTTATTACTCAAGACGGTCAGACAATACCCGTTGAAATAAATGGATTCACACAAGATGGAGAGGAATCGCCCATGCAGGATGTTTCTGTTCCCGAATCGGAATTAAAGGAAGATGATCCCAGTTCCCCAGTCACACATTACTATACTATTGTATAA
- Protein Sequence
- MEVVLYNSTVCRLCGEENDNGTFLYSTEENNQNISDLVNAYLPIKVSDDGQLPRTICPGCTIQLEATVEFINLIVTGQKTIRSLYNREKEYKKNLNKASGNDTNETIHIEVDSLGTNGVYQEEHPISLQVAGLDKPKRKRGRPPKKIKPPDELALEAAAIQQEVKIKQRDEEPTGKRRRKTPERFKEVVQGKELDQIFKEEGMTDGEVSEDEVKPEKIKPPKEQVLKSPEVIGHTSVSGELVVVVKGNGRGRPKGRTKQTRETCAICGKEFSNAGRYMSHIAQHGPVLYQCQQCRHTFSIRLEYNEHKRETGHEGLNILPGKDEDNIDSEAPSQVLATPPNPHQPPAEIFATPEPPAVKLDDGMAATVGSLPDLSAQPAELMNVEFLKLPELQAEGNEDEQKKEINKTEFKDSLTVEEPVPKKYKLKCPHCDKKYSSKQAKSMHIKAAHKGERPYICNECGASFAYPRALTLHALAHRRRTTSKGFACDLCGKVLNHPSSVAYHKEAEHANQRYVCNKCGKHFKHKQLLQRHQLVHTQNRPFHCKTCNSKFKTKANLYNHQMLHTGVKKFSCEECKQRFAHKTSLTLHMRWHRGQKPFACKYCDKAFTQKGNLSEHLRIHTGEKPFQCVLCPRRFTTSSQHRLHLRRHEPKQHRACPRASATEATTRSIVSSDGSVIQLTVGGGDVGDGGDVGDGGDVVTGHKCAWCPRVCGTRWTLAKHQRLHTGERPFQCPICKRCFADASNLNKHKKQIHKQTSLLALQPLPPESETECHVELPSQPQYVVQTEEDEERVIYVTYDVNEQEPAYEILESEQDDFSMEALSPKDCELYSGESLLLQHKMQEEQEHMSVTDEQGNPLHFTMQDGTRLAITSLDGQSLQVITQDGQTIPVEINGFTQDGEESPMQDVSVPESELKEDDPSSPVTHYYTIV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01171679;
- 90% Identity
- iTF_01171679;
- 80% Identity
- -