Basic Information

Insect: Perizoma affinitatum
Gene Symbol: ZFX
Assembly: GCA_961405105.1
Location: OY560184.1:1008518-1011281[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 8.2e-07 5.3e-05 23.9 0.8 2 23 100 121 99 121 0.96

2 14 0.00014 0.0089 16.9 1.5 1 23 127 149 127 149 0.97

3 14 3.4e-06 0.00022 22.0 3.5 1 23 154 177 154 177 0.96

4 14 0.00049 0.032 15.2 3.9 1 23 183 205 183 205 0.98

5 14 4.5e-06 0.00029 21.6 0.9 1 23 211 233 211 233 0.97

6 14 1.7e-05 0.0011 19.7 1.0 1 23 239 261 239 261 0.97

7 14 2e-06 0.00013 22.7 0.8 1 23 267 289 267 289 0.97

8 14 0.00077 0.05 14.5 6.2 2 23 302 323 301 323 0.96

9 14 2e-08 1.3e-06 29.0 0.5 1 23 329 351 329 351 0.99

10 14 2.5e-06 0.00016 22.4 0.3 1 23 357 379 357 379 0.97

11 14 3.2e-07 2e-05 25.2 0.4 1 23 385 407 385 407 0.98

12 14 0.00026 0.017 16.0 1.0 1 23 413 435 413 435 0.94

13 14 8.8e-06 0.00057 20.6 5.4 1 23 441 463 441 463 0.98

14 14 3.4e-06 0.00022 22.0 1.1 1 20 469 488 469 488 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	8.2e-07	5.3e-05	23.9	0.8	2	23	100	121	99	121	0.96
2	14	0.00014	0.0089	16.9	1.5	1	23	127	149	127	149	0.97
3	14	3.4e-06	0.00022	22.0	3.5	1	23	154	177	154	177	0.96
4	14	0.00049	0.032	15.2	3.9	1	23	183	205	183	205	0.98
5	14	4.5e-06	0.00029	21.6	0.9	1	23	211	233	211	233	0.97
6	14	1.7e-05	0.0011	19.7	1.0	1	23	239	261	239	261	0.97
7	14	2e-06	0.00013	22.7	0.8	1	23	267	289	267	289	0.97
8	14	0.00077	0.05	14.5	6.2	2	23	302	323	301	323	0.96
9	14	2e-08	1.3e-06	29.0	0.5	1	23	329	351	329	351	0.99
10	14	2.5e-06	0.00016	22.4	0.3	1	23	357	379	357	379	0.97
11	14	3.2e-07	2e-05	25.2	0.4	1	23	385	407	385	407	0.98
12	14	0.00026	0.017	16.0	1.0	1	23	413	435	413	435	0.94
13	14	8.8e-06	0.00057	20.6	5.4	1	23	441	463	441	463	0.98
14	14	3.4e-06	0.00022	22.0	1.1	1	20	469	488	469	488	0.98

Sequence Information

Coding Sequence: ATGACCCAGAGAGCCGAACAAATCCTAACTCAACTATTTCATGATGGCTCGAAGgTAACACAAGAAGCAATTAAGTTGCTCAATAGAGGTACACCCTATAAGATCCAGCCTGTTGCTTTCTACAACTTCCCTATTGATGAGGATAATTGTGAAGTGGAAGATAGTCTTACAGAGGACTGCTTCAAACAGGAATCAGATAGGTTCCCGGTTGCATTTGAAGATGATTTTGTTTCTGAAGATGTAAAGAATGATTATGGCAAATATGAAGAAGGGAATTTAAAAGGCCACAGGCCTTGTGTCTGCGGCGTTTGCGGCAAATCATTTCCTGAAAAAAGCGACGTTAAAAAACATATGAGAATTCACACGCGTGAAAAGCCATTTTCCTGCCGTCTATGTGATATGAAATTTTATGGAAACTACCAATTGAAAAATCACATGAACGGTCACGCTGGAGAAAAGTTTACCTGCGAAATGTGTGATAAGACATTTTCCGAAAAGCACCAGCTTAGGAGACACGTTAGCAGAATGCACGCAGGACTGAAACCATATAACTGCGAATACTGCTATAAgtcattttatgaaaacaatCGGTTGCAACACCATATTAAAATCCACACGGGGGAAAAGCCATTTGCTTGTGACGATTGTCACAAAGCGTTTCCTGATAAACGCCGCTTGATTATCCACATGAGAAATCACACAGgggaaaagccatatgcctgcgATGTTTGCGAGAAGAAGTTTTCATCTCTAAACACTTTGAAACAACACACAAAAATACACACAGACAGCAAAATGTTCGCTTGTGATAAGTGCGATAAAACTTTCACAGTTTTGGATTACTTAAAAAGTCATATGAAAGGCCACTGCTCAGGAATGAGAAAGCCTGATAGTAGTGCATGCTCTTGCGATCGCTGTGGGAAGACATTCTTCGATAAATGTGTTCTGAAGAAGCATCTGAGAATACACACAGGAGAAAAGCCTTATGTTTGTGACAAGTGCGATAAGACTTTTGCTGAAAAGGGTAACTTAAAGCGGCACATTAGAATCCACACAGAGGAGAGACCGTTCGCTTGCGACTTGTGCGATAGGTCCTTCGCTGAAAGTGGAAACTTGAAGACGCACAGAAGAGTCCACACTGGCGAAAAGCCGTATTCTTGCGAAGCCTGCGGCAAAGGTTTTGCTCAATCCAGCTCTTTGAAAAAGCACCTCAACACCCACACAGGCGAGAAACAATTTTCCTGCATAGTCTGTTACAAAACTTTTACAGCTAAGAATAGCTTGAAAATACATATGAGGATTCATAGTGGAGAAAAGCCATTTTCATGCAACATATGTAGTAAATCATTTTATGAGAGTAGCTCATTATGTAGACATAAAAGAACGCATACGGGGGAGAGCCCATATACCTGCAGTAAATGCAATAAGCCTTTTAGTAGGAAAGCTTATTTACAACAACATATGCCGTTTTGCAAACGTCTTTGA
Protein Sequence: MTQRAEQILTQLFHDGSKVTQEAIKLLNRGTPYKIQPVAFYNFPIDEDNCEVEDSLTEDCFKQESDRFPVAFEDDFVSEDVKNDYGKYEEGNLKGHRPCVCGVCGKSFPEKSDVKKHMRIHTREKPFSCRLCDMKFYGNYQLKNHMNGHAGEKFTCEMCDKTFSEKHQLRRHVSRMHAGLKPYNCEYCYKSFYENNRLQHHIKIHTGEKPFACDDCHKAFPDKRRLIIHMRNHTGEKPYACDVCEKKFSSLNTLKQHTKIHTDSKMFACDKCDKTFTVLDYLKSHMKGHCSGMRKPDSSACSCDRCGKTFFDKCVLKKHLRIHTGEKPYVCDKCDKTFAEKGNLKRHIRIHTEERPFACDLCDRSFAESGNLKTHRRVHTGEKPYSCEACGKGFAQSSSLKKHLNTHTGEKQFSCIVCYKTFTAKNSLKIHMRIHSGEKPFSCNICSKSFYESSSLCRHKRTHTGESPYTCSKCNKPFSRKAYLQQHMPFCKRL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -