Basic Information

Insect: Penthetria funebris
Gene Symbol: zfh2
Assembly: GCA_027564355.1
Location: JANSTX010000069.1:1-7938[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.56 35 5.0 4.6 2 23 79 101 78 101 0.96

2 9 0.004 0.25 11.8 0.0 3 23 340 361 338 361 0.95

3 9 0.03 1.9 9.0 0.2 3 21 451 469 449 473 0.89

4 9 0.0015 0.096 13.1 2.0 1 23 519 541 519 541 0.96

5 9 0.00053 0.033 14.5 2.4 2 23 548 570 547 570 0.94

6 9 0.025 1.6 9.3 4.5 1 23 778 802 778 802 0.91

7 9 0.01 0.64 10.5 0.6 1 22 824 845 824 848 0.89

8 9 0.0046 0.29 11.6 0.1 1 23 1007 1031 1007 1031 0.93

9 9 0.89 55 4.4 2.7 1 19 1276 1294 1276 1299 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.56	35	5.0	4.6	2	23	79	101	78	101	0.96
2	9	0.004	0.25	11.8	0.0	3	23	340	361	338	361	0.95
3	9	0.03	1.9	9.0	0.2	3	21	451	469	449	473	0.89
4	9	0.0015	0.096	13.1	2.0	1	23	519	541	519	541	0.96
5	9	0.00053	0.033	14.5	2.4	2	23	548	570	547	570	0.94
6	9	0.025	1.6	9.3	4.5	1	23	778	802	778	802	0.91
7	9	0.01	0.64	10.5	0.6	1	22	824	845	824	848	0.89
8	9	0.0046	0.29	11.6	0.1	1	23	1007	1031	1007	1031	0.93
9	9	0.89	55	4.4	2.7	1	19	1276	1294	1276	1299	0.92

Sequence Information

Coding Sequence: ATGCAACTTGAAAATCAAATtactggttatggcagtattggaggtggtggtagtaatactagtagtagtggcggtggttgcggtagtacagctgcctctgctggtggtgttggcggaattggtggtggtattattggtagtggtaatattggtgctggtatgatggtacatcctggcacaacaattaataataataataataataataataataatacaccaacaacaatattaaAATGTAATCATTGTGATTATTTTACTGAAACAAAACATGAAATTGATCATCATTTAAATGTAATTCATCCAAATAGTTGCGAAAATGATTTCATTGTTATTCCAACAAATCCATTAAGTATTATGGCATTTCAAGCTGCTGCTGCTGCAGCAGCGGCCGCGGCCGCCGCAGCTACACAAGGTTTATCAACATCATCATCATTATCAATGCACCAAGGTCATCATGGACATAAAATTAAATTCACAAATGATGACATTAAATTGGAAAAAATGGATGCCGACGATGATGCCGAATATTTTTcgagcagtggtactattgaccatcaccatcaacacttgcatcatcaacaacatcagcaacaacaacaattactccatcaccatcaacaacaacaacaacagcaacaacaacagcaacaacaacaacaacaaaaacaccaaagtcatcaactgcaacagcagcaacaacagcaacaacaacaacatcaacaacagcatcgccgccattcatttggcggtgctggtgttagtaatgatgttggtgaaattgatgatagtgaaaatttatcacaatcattacgcacaatatccagttcctcaacaaacattaatagaaccactgagacaatgataaatgatgataatgatattgataatgatgatgacattatggatggtattgatgatgaaagtgaagatgatgatattgacgatgatgatgatgatgataatgatgatatgattgaggacgatgaagacgatgacggtttaattggtataatatgtccattgtgtcaagatagttttcctgataaaaaatcattagaaaaacatgttatgatagtgcatagtgttaatagcgatggattggcaagactcttgaatttagttgatgctagtcattggttaaatagtaaaaaaagtccagacagtaatgttaaaaacaataataataataatagtaataataataataataataataataataatattagtaacagttccaattgtggagaaaatacacttcaaatgtcttcatcaacaaataatacatcatcaACTGGTGCCACAAGTTGCATGAAAAACTATGACCACGATGGTACTGACATCGATTGTCAAATTTGTGGTAATAATTTCAAATCAATGTCAGATTTATTGCAACATTCAAATGAATTACAACATTTTACAATAATAAATGATTTATACAAATGCATCTTAAAAACATGTTCGCAAACATTTTTAAACGTTACCAATATGACAACCCATTTTAAGGATAGCCATATGAATATTGTCATATCTGAGCGTCATGTTTACAAATATCGTTGTAAATTATGTTCATTGGCATTTAAAACACAAGAGAAATTAAATACACATTCATTGTATCATACAATGCGTGATGCAACCAAATGCAATTTATGTAATCGTAATTTTCgcagcacaacatcattaaaaaaacatatcgaacaaatgcacaataatgtttcaatatcaacagcagctacaacaataacaacaacaacaacatcaacaacaacaacaaccacaacaacaacaacaacaacaacatccacaacagccacattatcttcatccacaacatcaccattaatcatgacaacacaatcaataacaccaacaactttgtcagtatcatcagcatcttcaccgccaccattaaatacatctatggaatcaccagatagtgctaattatgataataaaaatgatttagatgattataataatatgatgatgatgatgacgacaacaacaacaacaacaacaacaacaacaacaccaacagatggtgtcaccgctaatattttgccaaatataaaacaagaagatttagcacatgaacaaaatgatattagtgtaggtggtattgatggtcgaaatgctaatactattttaaatgatgaacaatactttaataataataataataataataataataatacgtcaggtaatattgatggtaatTCGTCATCATGTTCAATGTTACCAATGCCAACTGAAACAACTGAAATTGATGAATATTTAAATTCACAACAAATGGCCGAAGATAATTACAATGATTTAAATCGAAAATTTAAATGTCATAAATGTAAAATGGCATTCACAATACAATACTTTTTAATACAACATTATAAATCGAATACACATCGGCGAAATGAGAAAATTAACAATAATTATCCATTAGAAAAGTATTTGGATCCAAATCGGCCATTTAAATGTGAAATATGTCGTGAAAGTTTTACACAAAAGAATATTTTATTGGTTCATTACAATAGTGTTTCACATTTACACAAATTGAAGAAACAACAAAATGAGAATACCAATTTGGCAacagttgcatcgtcgacatcaacaataatgggaacatcggtaacgacaacatcaattactggcaacacaataatatcaacaccagccacaagtcccacaaataatgaaTTTGATCGGAAAAGTATTGAATATGATCGACGTAGTTTAGATGTTGATCGTAAAAGTATTGATTTTGATCGTAAAAGTATTGATTTTGATCGTAAAagtattgatttggattatgaaaatgaattacaacaattgcaacaacagcaattaatacaacaacaatttcaacaacagcaacagcaacaacatcatcaacaccaacaacaacaacaacaacaacaacaacaacaacagcaacaacaattgcaacagcaacaccaacaattaatgcaaaaacgcaaattgagtccagaaaatgaTTATGATAGTCCAAAGAAACGTTTCAAATGTGACATATGCAAAGTTGCTTATGCACAAGGTAGCACTTTGGACATACATATGCGTAGTGTATTACATCAAACACGCGCCTGTCGCCTTCAAGAACAACAACTAAGTTCCTCATCATCGTCATCTACAACACCAACAATAACATCATCTGTGCTTCATTCACAACAATCACAACAACAATTATCACCACATGGTTTATCACCAACAAATTTAATGACACAATCACGTCAATTTGATCAACAACAGCATTCAATCAATAGTATTAGTCCGACACCATCAAATTTAAGTATTAATCAAGAAATGCCAATGACTGAAAATTCACCAAAAATTAATAACCAAATTTATAAAACACTTTTAGAAAATTTTGGCTTTGATATTGTAAAACAGTTtaatgaaatcaataagattgatcaacaacaacaaaatcgtattaatagtaataataataataataataataataataatagtaataacaatgcaaacaacaatattaatatcaattccaataataatagccaaaacaacaataataataataataataatgataaaaacgaaaatagtaaatttggcaacagtggcaacagttgcggtggtgtgtcaataacaccaaccacaacaaccccaataacaaccgaaacatcagcagcaacatcaacactaacattatcaacaacaccattttcacttgcatcaacaaaaccgtcatgcacaacattaccattttcatcaacatcaccaatgaccccatcacaaacaggcacaataactttattgagtcaaaattccgatgaaaaatattattgtcGTCAATGTAAGAAAATTTTTTCCAGTATATTCGTACTGAAAACACATTGTGAAGAAATTCACAATGAGAAAATACCATTGGAATTTTTGGAGAAATTTGCCGAAAAATTTAAGAATTATTATCTTGATACAACTGCAACAACATCAAATCCAAGTGGTAATACAAGTGGCGATGGTCTACTAACAACAAAACAATGTACATCATCATATTCAATGTCTACAACGTCTGCAATAACAAGTGCAGTACAACAATTAACAACGCCAACAACATCACCAACAACAATATTACAAATGGCCGAAATGAGTCCATCCAGTGGCAACACTATAAATAATTCGGCAAATAATTCAACAAAATTGTCAATGTCATCGATAATGAGTGAAAATAATGACAATGAAATATTGGATTTTTCATCAAAAAAAGATTTAAAAGAAAATGTAAGAAATGAAAACCAAACATTTTTAAATTCACCAACATTTGCCGGTAATTTGGGTAATAATAATGTACCAGATTTAGCACAAAAATTAAATATCGATCCGCAAATATTGGCACAAAAAATGATGGAACAAAATTTCACCCAAAATTCCCTAAATTTTCCCCAAACATTACAGAATTTACAAAATTTACCGAATATTGCGGCTGCGGCCGCAGCAGCCGCTGCTGCCGCTAACGGTGGTGGTAATAATAATGGAGGTGGCGCTGCAAATGGCGGTAATAATACGGGAAATGGAAATATACCATTAAATACAATTGATATGTTAAATTTAATGCAATTTCATCATTTAATGTCATTGAATTTTATGAATTTAGCACCGCCATTAATTTTTGGTGCTACtggaaccggtggtggtggtggtggtggtggtggtggtagtgcctcatcgggtacaattggtaatagtggcattggtggcggtattagtggtaataataatgtcaataataataatattggtaatattggacaatcatcaaatgaattaaatttatctggtggagcgcaacaagtacaaatgttacagcaacaagcagctgctgcggcagcagcgcaagctgcagctgtacaacaGGCGTCAAATAATCAAAAACGAGCTAGAACTCGCATCACAGATGAACAACTGAAAATATTACGTGCCCATTTTGACATAAACAATTCGCCGAGCGAAGAGAGTATTATGGAAATGTCAAAAAAGGCCAATTTGCCGATGAAGGTTGTTAAACATTGGTTTCGAAATACATTATTTAAAGAACGACAACGTAATAAAGATTCACCCTATAATTTCAATAATCCACCATCAACAACATTGAATCTTGAAGAATATGAACGTACTGGTCAAACAAAAGTTACGTCACTTAATGATCCGATTGATGTAAGTgcaactgttgtaacaaatcaacaacaacagcaacaattacaacaaaatcaacaattaccacaaacaactcagcaaatgttacaggcaatacaactacaacaacaacaacaacaacaacagcagcaacaacaacaacagcaacaacaacaacagcagcaacaacaacaacaacaacaacaacaacaacagcagcaacaacagcaacaacaacaacaacagcagcaacagcaacaacatcaacaacagcagcaacaacagcaaatgttattgcaacaacaacaacaacaattacaacaattgcaacaacaacaacaagataatcgaccactttcgcaaccatcaagtattgccagcagtagtgatcatcaacatcgtcatcaagacaacattattCAGGTAAAATCTGAACCAATTGGTGGTGATGATGGAATGTTGATGATGGACGGCATCGTAAATTGTAGTAATAATATAAATAATTGTTTAAAAAGTGAACAAATGTTAATTGATCATGATCATAATAGTATGCATTCGCATCATCAAAATATGTATTATAATAATAATTTCGAAACAAAATCGGAAAGTGGTAGTTCGGAAATTTTATCTAGACCACAAACACCAAATTGTAGTTCCTATAATAATATCAATGATATTATCAATCAACAAATTGAAAGTATACCAATAAATAATATAACAAATATTGGCAGCCTAAATAGTATGGGGCCACCGAAAAAATTTCAATTAAATAAAATATTTGATAAAAGTTTCGAATCGAATTCAAATTCATCGAATTCATCGACATCTAGTGGTAAACGGGCAAATCGTACCCGTTTCACTGACTACCAAATAAAAGTATTGCAAGAATTTTTCGAAAATAATTCTTATCCAAAAGATAGTGATTTAGAATATTTGAGTAAACTTTTATTGTTATCGCCACGTGTTATTGTCGTATGGTTTCAG
Protein Sequence: MQLENQITGYGSIGGGGSNTSSSGGGCGSTAASAGGVGGIGGGIIGSGNIGAGMMVHPGTTINNNNNNNNNNTPTTILKCNHCDYFTETKHEIDHHLNVIHPNSCENDFIVIPTNPLSIMAFQAAAAAAAAAAAAATQGLSTSSSLSMHQGHHGHKIKFTNDDIKLEKMDADDDAEYFSSSGTIDHHHQHLHHQQHQQQQQLLHHHQQQQQQQQQQQQQQQQKHQSHQLQQQQQQQQQQHQQQHRRHSFGGAGVSNDVGEIDDSENLSQSLRTISSSSTNINRTTETMINDDNDIDNDDDIMDGIDDESEDDDIDDDDDDDNDDMIEDDEDDDGLIGIICPLCQDSFPDKKSLEKHVMIVHSVNSDGLARLLNLVDASHWLNSKKSPDSNVKNNNNNNSNNNNNNNNNNISNSSNCGENTLQMSSSTNNTSSTGATSCMKNYDHDGTDIDCQICGNNFKSMSDLLQHSNELQHFTIINDLYKCILKTCSQTFLNVTNMTTHFKDSHMNIVISERHVYKYRCKLCSLAFKTQEKLNTHSLYHTMRDATKCNLCNRNFRSTTSLKKHIEQMHNNVSISTAATTITTTTTSTTTTTTTTTTTTTSTTATLSSSTTSPLIMTTQSITPTTLSVSSASSPPPLNTSMESPDSANYDNKNDLDDYNNMMMMMTTTTTTTTTTTTPTDGVTANILPNIKQEDLAHEQNDISVGGIDGRNANTILNDEQYFNNNNNNNNNNTSGNIDGNSSSCSMLPMPTETTEIDEYLNSQQMAEDNYNDLNRKFKCHKCKMAFTIQYFLIQHYKSNTHRRNEKINNNYPLEKYLDPNRPFKCEICRESFTQKNILLVHYNSVSHLHKLKKQQNENTNLATVASSTSTIMGTSVTTTSITGNTIISTPATSPTNNEFDRKSIEYDRRSLDVDRKSIDFDRKSIDFDRKSIDLDYENELQQLQQQQLIQQQFQQQQQQQHHQHQQQQQQQQQQQQQQQLQQQHQQLMQKRKLSPENDYDSPKKRFKCDICKVAYAQGSTLDIHMRSVLHQTRACRLQEQQLSSSSSSSTTPTITSSVLHSQQSQQQLSPHGLSPTNLMTQSRQFDQQQHSINSISPTPSNLSINQEMPMTENSPKINNQIYKTLLENFGFDIVKQFNEINKIDQQQQNRINSNNNNNNNNNNSNNNANNNININSNNNSQNNNNNNNNNDKNENSKFGNSGNSCGGVSITPTTTTPITTETSAATSTLTLSTTPFSLASTKPSCTTLPFSSTSPMTPSQTGTITLLSQNSDEKYYCRQCKKIFSSIFVLKTHCEEIHNEKIPLEFLEKFAEKFKNYYLDTTATTSNPSGNTSGDGLLTTKQCTSSYSMSTTSAITSAVQQLTTPTTSPTTILQMAEMSPSSGNTINNSANNSTKLSMSSIMSENNDNEILDFSSKKDLKENVRNENQTFLNSPTFAGNLGNNNVPDLAQKLNIDPQILAQKMMEQNFTQNSLNFPQTLQNLQNLPNIAAAAAAAAAAANGGGNNNGGGAANGGNNTGNGNIPLNTIDMLNLMQFHHLMSLNFMNLAPPLIFGATGTGGGGGGGGGGSASSGTIGNSGIGGGISGNNNVNNNNIGNIGQSSNELNLSGGAQQVQMLQQQAAAAAAAQAAAVQQASNNQKRARTRITDEQLKILRAHFDINNSPSEESIMEMSKKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYERTGQTKVTSLNDPIDVSATVVTNQQQQQQLQQNQQLPQTTQQMLQAIQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQMLLQQQQQQLQQLQQQQQDNRPLSQPSSIASSSDHQHRHQDNIIQVKSEPIGGDDGMLMMDGIVNCSNNINNCLKSEQMLIDHDHNSMHSHHQNMYYNNNFETKSESGSSEILSRPQTPNCSSYNNINDIINQQIESIPINNITNIGSLNSMGPPKKFQLNKIFDKSFESNSNSSNSSTSSGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01168274;
90% Identity: iTF_01168274;
80% Identity: iTF_01168274;