Pfun003286.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Penthetria funebris
Gene Symbol
Zfy2
Assembly
GCA_027564355.1
Location
JANSTX010055208.1:4155-10337[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.019 1.2 9.7 0.3 1 23 250 273 250 273 0.96
2 16 0.014 0.85 10.1 3.3 1 20 284 303 284 305 0.93
3 16 0.00029 0.018 15.4 0.3 2 23 318 340 317 340 0.96
4 16 0.00062 0.038 14.3 2.8 1 23 346 368 346 368 0.97
5 16 3.6e-05 0.0022 18.2 1.8 1 23 374 397 374 397 0.97
6 16 0.0057 0.35 11.3 3.0 1 23 402 424 402 424 0.97
7 16 0.00063 0.039 14.3 8.7 1 23 430 452 430 452 0.99
8 16 2.5e-05 0.0015 18.7 2.7 1 23 458 480 458 480 0.96
9 16 5.5e-06 0.00034 20.8 0.3 1 23 486 508 486 508 0.98
10 16 2e-08 1.3e-06 28.5 2.1 1 23 514 536 514 536 0.99
11 16 0.00018 0.011 16.0 1.8 1 23 542 565 542 565 0.96
12 16 5.2e-05 0.0032 17.7 1.9 1 23 599 621 599 621 0.98
13 16 1.9e-05 0.0012 19.1 1.4 1 23 627 650 627 650 0.94
14 16 5.2e-06 0.00033 20.9 0.9 1 23 656 678 656 678 0.98
15 16 0.00037 0.023 15.0 3.2 1 23 684 706 684 706 0.98
16 16 0.0053 0.33 11.4 0.9 1 23 712 734 712 734 0.99

Sequence Information

Coding Sequence
ATGACAGACATTAACTCACAGGTTGTTTATAGTTTACAACAAACATGCAGAACATGCTTATTAACAGAACATGAGCAAATAATGATAAATATATTTTGTAACGATATTAATAATGCACCAATTTTAATATTGGAAGAACTAGGTTTTTTTAAATTAAAGatagtacaaggtgacggtttACCACAACAAATATGCACTGCATGTATGAAACATTTACAAGATTTCAGTACATTTCGAACGAATTGTGAAAGATCTGAAAATATTTTAGAGCATTATTTTAAACAAACAAATCATAATCTATTGAATAAAATTGAAGAACATAATGTGGAAgatgttaatgtagaaataactaataatacaaatatgaattcaattgatgataattatgaagattataataatggtgatgaacacgaagagaacgttgcaaataatgatggtgatgatgatgatgatgatgatgatgatgatggtgatggtgatagtgctgatgaagattataattgtaatgttgatgctaatgaaaataatgatagttttgatgaaaataaattattgataataaataaattagaatttaatgatgaaatgaagactgataataaatctcatgataatattataacacaagaagaaattgatgatattgatgatagtcataatcaatttatgtccaatataaaagatgttaataatgatgaaaatgGACATAGTTTTGAAAATTCAGTAACATTGCAAATCAACCGATTTGAATGTAGTCTTTGTTTAAATGCATATGAAACTGAATCGTTTTTATTGCGACATATGTCAATCACTCACAATGATATTGATTCAAAAAAAGCATATAAATTTGAATGCACAAAATGTGGCAAATGTTTTTTAAAGCAGAAATCTATGGAAAAGCATAAAAATGAGGGAAATTGTGCTGATATAATTGATGATGGACAAATTCGTTGTAAATATTGTAAGGAAATATTTGATGAAAATGAACAATTAGAAGAACATTTAAAAAAAGCACATCCAAAAGATAGACCACATATGTGTCCAGTGTGTAAGAAAAATTTTCAAAGTGTATCTAATCGTAATACTCATATGCAATCGCATAATAAAGATGATTCATATAAATGTGATGTTTGTAATCAAGGTTTTAAAAGTAAAGTATATCTTAGTAAGCATAAAAAATCGGTGCACACAATTTCGGAACATAATTGTCCATATTGTTCGTTACAatttgataataaagttaaatttgaataccatttaaaatcacatgatccaaataagaaatataaatgtaaatattgtgataaatcatttcttcaacatcatcatttggctaatcatgaaagaacacacactggtctaagaccatacctatgtagtatttgtggtaaagattttaaacaagaatgtaattttaaacttcatttacgaatacatagtggacataggccgtatatatgtaatgtatgtggtaaAGATTTTATCCAACGTGGTTCATTTGTTATGCATATGCGTCAACATTCTGGCATAAGACCATATCAATGTGAACATTGTGGAAAAGactttgttcaaaaatcatcgttaaccgttcatttgcgtacacataccggtgaaaagccatataaatgtgattcatgtgatagagcatttgtacaagcacaacaattaaaatatcatcggcattcggcacatggtggaccaccgtTAAAAAAAGAAAACACAAATCATAGTAATAAGAACAATAATACTAATATAACAAAAGCACCATCATCTGATGGCCGTATTTATCCATATTGTTGTCAATTATGTAATAAAGGGTTTAAATTACCGTCATCATTGTCATCacacataaaaattcataatgaagaacgtaaacacatatgtacacagtgtggtaattccttcaagcgtgccgaacatttacgtatacatattaatggtgtccatttaaaacaaaaaccatatgcatgtgaaatgtgtaataaaacatttagtcaatcgggtgatcgtaatattcatatgaaaagacatagtggtgaaaaacctcatcaatgtcaatattgtaaaaagaatttccgattattaaaggctatgcgagctcacttacgcattcataccggtgaacgtccatataaatgtgaattatgttcCGTTGATTTTATGACGTACACATCCCTTGCAACCCATACAATGAAACATCAACATGAGGAAGCAACGAAGACAACTAGTACAAATTTACAAATATCTGAAGAACTAAGTTTAGAAAGCAAACCATTAATTACATTCTCTTCATCAAGTAATACACCATTAAGTGATGATGGTTGTAACAAATCAGTATCTCAATGTCATGAAATTAAGGGTGAAGAACTAATTGATCCAGTAAAATCAAATTAA
Protein Sequence
MTDINSQVVYSLQQTCRTCLLTEHEQIMINIFCNDINNAPILILEELGFFKLKIVQGDGLPQQICTACMKHLQDFSTFRTNCERSENILEHYFKQTNHNLLNKIEEHNVEDVNVEITNNTNMNSIDDNYEDYNNGDEHEENVANNDGDDDDDDDDDDGDGDSADEDYNCNVDANENNDSFDENKLLIINKLEFNDEMKTDNKSHDNIITQEEIDDIDDSHNQFMSNIKDVNNDENGHSFENSVTLQINRFECSLCLNAYETESFLLRHMSITHNDIDSKKAYKFECTKCGKCFLKQKSMEKHKNEGNCADIIDDGQIRCKYCKEIFDENEQLEEHLKKAHPKDRPHMCPVCKKNFQSVSNRNTHMQSHNKDDSYKCDVCNQGFKSKVYLSKHKKSVHTISEHNCPYCSLQFDNKVKFEYHLKSHDPNKKYKCKYCDKSFLQHHHLANHERTHTGLRPYLCSICGKDFKQECNFKLHLRIHSGHRPYICNVCGKDFIQRGSFVMHMRQHSGIRPYQCEHCGKDFVQKSSLTVHLRTHTGEKPYKCDSCDRAFVQAQQLKYHRHSAHGGPPLKKENTNHSNKNNNTNITKAPSSDGRIYPYCCQLCNKGFKLPSSLSSHIKIHNEERKHICTQCGNSFKRAEHLRIHINGVHLKQKPYACEMCNKTFSQSGDRNIHMKRHSGEKPHQCQYCKKNFRLLKAMRAHLRIHTGERPYKCELCSVDFMTYTSLATHTMKHQHEEATKTTSTNLQISEELSLESKPLITFSSSSNTPLSDDGCNKSVSQCHEIKGEELIDPVKSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-