Basic Information

Gene Symbol
-
Assembly
GCA_963921195.1
Location
OY992538.1:168024546-168030128[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 35 9.7e-05 0.0082 17.9 0.2 1 23 10 33 10 33 0.97
2 35 0.034 2.9 9.9 1.1 2 23 143 165 142 165 0.97
3 35 1.6 1.4e+02 4.6 5.0 1 23 171 194 171 194 0.94
4 35 0.00048 0.041 15.7 1.4 1 23 199 221 199 221 0.94
5 35 2.3e-05 0.0019 19.8 1.1 3 23 230 250 228 250 0.96
6 35 0.00013 0.011 17.5 1.8 1 23 261 283 261 283 0.95
7 35 6.8e-05 0.0058 18.3 2.4 2 23 291 312 290 312 0.97
8 35 0.016 1.4 10.9 4.3 1 23 318 341 318 341 0.98
9 35 0.00058 0.05 15.4 3.2 1 23 426 449 426 449 0.98
10 35 1.2e-05 0.0011 20.7 0.6 1 23 456 478 456 478 0.98
11 35 3.6e-05 0.0031 19.2 1.1 1 23 482 505 482 505 0.98
12 35 6.1e-05 0.0052 18.5 0.8 1 23 622 645 622 645 0.98
13 35 0.00012 0.01 17.5 0.3 1 23 652 674 652 674 0.98
14 35 2.1e-05 0.0018 20.0 1.6 1 23 678 701 678 701 0.98
15 35 0.0063 0.53 12.2 0.6 2 23 782 803 781 803 0.97
16 35 0.034 2.9 9.9 1.1 2 23 842 864 841 864 0.97
17 35 1.9 1.6e+02 4.4 4.4 1 23 870 893 870 893 0.91
18 35 0.00048 0.041 15.7 1.4 1 23 900 922 900 922 0.94
19 35 0.00022 0.018 16.8 1.4 3 23 931 952 929 952 0.95
20 35 0.0045 0.39 12.6 2.4 1 23 959 981 959 981 0.97
21 35 0.00084 0.072 14.9 1.3 1 23 987 1010 987 1010 0.98
22 35 3.8e-05 0.0032 19.2 1.7 1 23 1060 1083 1060 1083 0.98
23 35 0.0063 0.53 12.2 0.6 2 23 1164 1185 1163 1185 0.97
24 35 0.034 2.9 9.9 1.1 2 23 1224 1246 1223 1246 0.97
25 35 1.9 1.6e+02 4.4 4.4 1 23 1252 1275 1252 1275 0.91
26 35 0.00048 0.041 15.7 1.4 1 23 1282 1304 1282 1304 0.94
27 35 7.4e-05 0.0063 18.2 1.4 3 23 1313 1334 1311 1334 0.95
28 35 0.00036 0.031 16.1 1.5 1 23 1340 1362 1340 1362 0.97
29 35 0.00061 0.052 15.4 0.6 1 23 1368 1391 1368 1391 0.97
30 35 0.00026 0.022 16.5 3.1 1 23 1441 1464 1441 1464 0.98
31 35 0.0063 0.53 12.2 0.6 2 23 1545 1566 1544 1566 0.97
32 35 0.09 7.7 8.5 0.9 2 23 1605 1627 1604 1627 0.97
33 35 0.7 59 5.7 3.0 1 23 1633 1656 1633 1656 0.90
34 35 0.00094 0.08 14.8 1.4 1 23 1663 1685 1663 1685 0.94
35 35 2.2e-05 0.0019 19.9 1.1 3 23 1694 1715 1692 1715 0.95

Sequence Information

Coding Sequence
ATGCGCTATCACAACAACAAGAAGCAATTTAAATGTGGCATATGTTCAGAAGAATTTGTCAACCCAGAATCACTTACAAGACATGCTAAAAAAAATCATACTGATGCCACAACATCTTCACTCGAAAAAGATGTATCAGAATTAATTAATGAAAATGATCTATTAGAAGATTCCCCTGCATCTTCTTATATGCACATTTCGAGTAAAGATGTGCTAAAACCTGTCAAAGATAATGAATATAAAGTTGTGGAACTTCAAGAACATGATCCTAAAATATATTCATCATCTTCTAATAAAGACATTTTGTGGGATTCCCAGAAAAATACACCTAATCAAAACCAATCTGTTTATTGTggcaaacaattaaaaaaaaaacgcagcACAACAAAACAATGGACACCCGGCGTtaatattcccgggaataatcAATGTCAATATTGTGGCATACAATTGAAAACATTTGAAACATACAAACAACATGTACGACGATTACATCCAAATGAAAACCCTTATAAATGTAAAACATGCAATAAGAGATATTTAACAGTTAATTGTCTAACTCGACATGAAAACCTTAAACACTCCGAAAGACCTTATAAATGTGATATTTGTTTGAGGAGTTTTAAACAATATGGAACTCTTAACCGTCATAAAGTGTTGCATTCTAAAATTCAACCACAGCATTTATGTTCGATATGTCCTGCTAAATATCGACGTAAAGACAATTTAAACATTCACATGCGCATTCATAGCCAACAACACTTCGATCATAAACGACCCCATAAATGTgatatttgtttaaaaagttttaagcaatTGTCAACTTTAACACAACATATAGTATTGCACTCTAAATTTCCACCGCTGCAATCATGTTCAGTATGTCCAGCTAAATTTCGACATAAACGAAATTTGAACGCCCACATGCAGAGACATACAAAAAAGAAACCATTTAAATGTGGCACATGTTCAACAGTATTTGCCCGCGAATGTTTCCTAAAaacacatataaaaaaatttcacagctATGCCACCACATCTAGAAATATTAACCCACTAGAAAAAGTTGAATCAGAATTAATTAATAAAGGTGGTCGATTAGAAGATTCCCCAGCATCTTCTAACATGTACATTTCAAATAAAGACGTTTTAAAACCAGCTAAAGACAATTCAGAAAATGATGTTGTAGAACTTACAAAACCTCCTCATAAATATAATGCACTGAAACCCCTAACTCGACATGAAAGCCTAAAACATTCCGATGATTACAGACCTTACAAATGTGATATTTGTTCATTTagtttcaaaaatgtatttactTTAAAACgacataaaaaaatgttgcactttgaCCTTCAACCGCAGTTTTCATGTTTGATATGTCCAGCTAAATTTCGACGTACCGATAACTTAGAATCTCACATGCGCAGTCATACAAAACCATTTAAATGTGGCACATGTTCAAAAGCATTTTCCCGCGCAGTTTTACTTAAAACacatatacaaaaatttcacAGCGATACCACCACTCCTTCATTAGAAAAGGATCAATCAGAATTAACTAATAAAGATGATCGATTAGAAGATATCCCTGCATTATCTAACATGCATATTTCTAATAAAGACGTTTTAAAACCAGCCGAAAAACCACCAGAAAAAGTTGAATCAGAATTAATTAATAAAGGTGATCGATTAGAAGATTCCCCAGCATCTTCTAACATGTGCATTTCGAATAAAGACGTTTTAAAACCAGCTAAAGACAATCAAGAAAATTATGTTGTGGAGCTTACAAAACCTCCTCATAAATATAATGCAGTAAAAACCCTAACTCAACATGAAAGCTTAAAACATTCCGATAGACCTTATAAATGTGATATTTGttcattaagttttaaaaatttaccaacttTAACACGACATACAAAAGTGTTGCACTCTGACCTTCCACCACAGTTTTCATGTTTGATATGTCCAGCAAAATTTCGACGTACAGATAGCTTAGATGCTCACATGCGCAGTCATACAAAACCATTTAAATGTGGCACATGTTCAAAAGTATTTGCCCGCGCATATTTACTTAAaacacatataaaaaaatttcacagcgATACCACCACTTCTTCATTGGAAAAGGATCAATCAGAATTAATTAATAAAGATGATCGGTTAGAAGATATCCCTGCATTATCTAATATGCATATTTCTAATAAAGTCGTTTTAAAACCAGCCGAAGACAATCCAGAAGATTGTGTTGGGGAACTGAAAGGAGATGATCATAAAATGTATTCAACTTTAAATAAAGAAATTTCTTGGGACTCCCAGAAAAACACTCCCAAAAGAAATCAATGTGGTTTCTGTGGAAAACAATTAAAAACGTCGGCGACATATAAAAATCATTTACTTGTTCATTCAACAAATGCGAGTAATAAACTTCATGAAATTTGTCATCCAGAAAATAACTTACAACAACAATGCAGTACAACACAACAATGGACACCCGGCGTtaatattcccgggaataatcAATGTCAATATTGTGGCATACAATTGAAAACATTTGAAACATACAAACAACATGTACGACGATTACATCCAAATGAAAAACCTTATAAATGTAAAACATGCAATAAGAGATATTTAACAGTTAATTGTCTAACTCGACATGAAAGCCTTAACCACTCTGGTACAGTTAGACCTTACAAATGTGATATTTGTTTGAGGAGTTTTAAACAATATGGAACTCTTAACCGTCATAAAGTGTTGCATTCTAAAATTCAACCACAACATTTATGTTCGATGTGTCCTGCTAAATATCGACGTAAAGACACTTTAACCGCTCACATGCGTATATATCATTCATCACATGCAACGCAGCATTCATGTTTAATATGTCCagctaaatttcgaaaaaaacaaaatttagtccTTCACAAGCGCAGTCATACAAACGCGAAACCGTTTAAATGTGGCACGTGTTTAAGAGTATTTGCCAGCTCAGATTTACTTCAAACACATACTAAAAAATTTCACAGCGATATCAACTTCTATTCAGTAGAAAAAGATGAATTAGTTAATAAAGATAATCGATTAGAAGACTCCATCTCATCTTCTAATATGCACATTTCGAATAAAAAAGTGTTGCACCCTGACCTTCCATCACATTTAAACCTTACACCATTTAAATGTGGCACATGTTCAAAAGTATTTGCCCACGCATATTTACTTCAaacacatataaaaaaaattcacagcGATACCACCACTTCTTCATTAGAAAAGAATCAATCAGAATTAATTAATAAAGATGATCGATTAGAAGATATTCCTGCATCATCTAATATGGATATTTCTAATAAAGACGTTTTAAAACCAGCCGAAGACAATCCAGAAGATTGTGTTGGGGAACTGAAAGGAGATGATCATAAAATGTAttcaactttaaataaaaaaatttcttgggaCTCCCAGAAAAACACTCCCAAAAGAAATCAATGTGGTTTCTGTGGAAAACAATTAAAAACGTCGGCGACATATAAAAATCATTTACTTGTTCATACAACTAATGCGATTAATAAACTTCATGAAATTTGTCATCCAGAAAATAACTTACAACAACAATGCAGTACAACACAACAATGGACACCCGGCGTtaatattcccgggaataatcAATGTCAATATTGTGGCATACAATTGAAAACATTTGAAACATACAAACAACATGTACGACGATTACATCCAAATGAAAGACCTTATAAATGTAAAACATGCAATAAGAGATATTTAACAGTTAATTGTCTAACTCGACATGAAAGCCTTAACCACTCTGGTACAGTTAGACCTTACAAATGTGATATTTGTTTGAGGAGTTTTAAACAATATGGAACTCTAAACCGTCATAAAGTGTTGCATTCTAAAATTAAACCACAGCATTTATGTTCGATATGTCCTGCTAAATATCGACGTAAAGACAGTTTAACCGCTCACATGCGCAGTTATCATTCATCACATGCAACACATTCATGTTTAATATGTCCAGCTAAATTtcgaaaaaaccaaaatttagtCCTTCACATGCGCAGTCATACAAACGCGAAACCGTTTAAATGTGCCACGTGTTTAAGAGTATTTGCCAGCTCAGATTCACTTCAAATACATACTAAAAAAGATCACAGCGATATCAACTTCTATTCAGTAGAAAAAGATGAATTAGTTAATAAAGTTAATCGATTAGAAGACTCCATCTCATCTTCTAATATGCACATTTCGAATAAAAAAGTATTGCACCCTGACCTTCCATCACATTTAAACCTTTCACCATTTAAATGTGGcacatgttcaaaaatatttgccCACGCATATTTACTTAAaacacatataaaaaaatttcacagcgATACCACCACTTCTTCATTAGAAAAGAATCAATCAGAATTAATTAATAAAGATGATCGATTAGAAGATATTCCTGCATCATCTTGTATGCATATTTCTAATAAAGACGTTTTAAAACCAGCCGAAGACAATCCAGAAGATTGTGTTGGGGAACTGAAAGGAGATGATCATAAAATGTATTCAACTTTAAATAAAGAAATTTCTTGGGACTCCCAGAAAAACACTCCCAAAAGAAATCAATGTGGTTTCTGTGGAAAACAATTAAAAACGTCGGCGACATATAAAAATCATTTACTTGTTCATACAACAAATGCGAGTAATAAACTTCATGAAATTTGTCATCCAGAAAATAACTTACAACAACAATGCAGTACAACACAACAATGGACACCCGGCGTTAATAGTCCCGAGAAAAATCAATGTCTCTATTGTGGCATACAATTGAAAACATTTGAAACATACAAACAACATGTACGACGATTACATCCAAATGAAAAACCTTATAAATGTAAAATATGCAATAAGGGATATTTAACAGTTAACTGTCTAACTCGACATGAAAGCCTTAAACATTCTGGTAATGATAGACCTTATAAATGTGATATTTGTTTGAGGAGTTTTAAACAATTTGCAACTCTTAACCGTCATAAAGTGTTGCATTCTAAAATTCAACCACAGCATTTATGTTCGATATGTCCTGCTAAATATCGACGTAAAGACAATTTAACCGCTCACATGCGCATTTATCATTCATCACATCACATCAAAAATCACAGCGATACCATCACATCTGGGAACACCAACACGTTGGAAAAATATGATTCAGAATTAATAAAAGACAATCGATTAAAATATGATTGTGCAGAAACTTTTGAGTACGAATCTAACATGTGTATTGATTTTCCTGAAGAAAGTCAGCAACAATTACCTTCCacatcaaaaacacaaattaggAATACTGAAAGCTCTATAATTCCACAAAATATTGTTAATGAGAACATCAAATCTATATCATTGCCTATGGAATCTATTCTATATGATGCTTCGAATTCTTCTACATCTAATATCGAatcaaattttattgaatttatcAAAGAGGAATATCAGATAGTAGAGCAAAATATTGGAGAATTAAAAACTGACAAGGCTGAACTTAGAAGCATCTATAATATAGAAGATTTTATCTAA
Protein Sequence
MRYHNNKKQFKCGICSEEFVNPESLTRHAKKNHTDATTSSLEKDVSELINENDLLEDSPASSYMHISSKDVLKPVKDNEYKVVELQEHDPKIYSSSSNKDILWDSQKNTPNQNQSVYCGKQLKKKRSTTKQWTPGVNIPGNNQCQYCGIQLKTFETYKQHVRRLHPNENPYKCKTCNKRYLTVNCLTRHENLKHSERPYKCDICLRSFKQYGTLNRHKVLHSKIQPQHLCSICPAKYRRKDNLNIHMRIHSQQHFDHKRPHKCDICLKSFKQLSTLTQHIVLHSKFPPLQSCSVCPAKFRHKRNLNAHMQRHTKKKPFKCGTCSTVFARECFLKTHIKKFHSYATTSRNINPLEKVESELINKGGRLEDSPASSNMYISNKDVLKPAKDNSENDVVELTKPPHKYNALKPLTRHESLKHSDDYRPYKCDICSFSFKNVFTLKRHKKMLHFDLQPQFSCLICPAKFRRTDNLESHMRSHTKPFKCGTCSKAFSRAVLLKTHIQKFHSDTTTPSLEKDQSELTNKDDRLEDIPALSNMHISNKDVLKPAEKPPEKVESELINKGDRLEDSPASSNMCISNKDVLKPAKDNQENYVVELTKPPHKYNAVKTLTQHESLKHSDRPYKCDICSLSFKNLPTLTRHTKVLHSDLPPQFSCLICPAKFRRTDSLDAHMRSHTKPFKCGTCSKVFARAYLLKTHIKKFHSDTTTSSLEKDQSELINKDDRLEDIPALSNMHISNKVVLKPAEDNPEDCVGELKGDDHKMYSTLNKEISWDSQKNTPKRNQCGFCGKQLKTSATYKNHLLVHSTNASNKLHEICHPENNLQQQCSTTQQWTPGVNIPGNNQCQYCGIQLKTFETYKQHVRRLHPNEKPYKCKTCNKRYLTVNCLTRHESLNHSGTVRPYKCDICLRSFKQYGTLNRHKVLHSKIQPQHLCSMCPAKYRRKDTLTAHMRIYHSSHATQHSCLICPAKFRKKQNLVLHKRSHTNAKPFKCGTCLRVFASSDLLQTHTKKFHSDINFYSVEKDELVNKDNRLEDSISSSNMHISNKKVLHPDLPSHLNLTPFKCGTCSKVFAHAYLLQTHIKKIHSDTTTSSLEKNQSELINKDDRLEDIPASSNMDISNKDVLKPAEDNPEDCVGELKGDDHKMYSTLNKKISWDSQKNTPKRNQCGFCGKQLKTSATYKNHLLVHTTNAINKLHEICHPENNLQQQCSTTQQWTPGVNIPGNNQCQYCGIQLKTFETYKQHVRRLHPNERPYKCKTCNKRYLTVNCLTRHESLNHSGTVRPYKCDICLRSFKQYGTLNRHKVLHSKIKPQHLCSICPAKYRRKDSLTAHMRSYHSSHATHSCLICPAKFRKNQNLVLHMRSHTNAKPFKCATCLRVFASSDSLQIHTKKDHSDINFYSVEKDELVNKVNRLEDSISSSNMHISNKKVLHPDLPSHLNLSPFKCGTCSKIFAHAYLLKTHIKKFHSDTTTSSLEKNQSELINKDDRLEDIPASSCMHISNKDVLKPAEDNPEDCVGELKGDDHKMYSTLNKEISWDSQKNTPKRNQCGFCGKQLKTSATYKNHLLVHTTNASNKLHEICHPENNLQQQCSTTQQWTPGVNSPEKNQCLYCGIQLKTFETYKQHVRRLHPNEKPYKCKICNKGYLTVNCLTRHESLKHSGNDRPYKCDICLRSFKQFATLNRHKVLHSKIQPQHLCSICPAKYRRKDNLTAHMRIYHSSHHIKNHSDTITSGNTNTLEKYDSELIKDNRLKYDCAETFEYESNMCIDFPEESQQQLPSTSKTQIRNTESSIIPQNIVNENIKSISLPMESILYDASNSSTSNIESNFIEFIKEEYQIVEQNIGELKTDKAELRSIYNIEDFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-