Phum007624.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pediculus humanus
Gene Symbol
-
Assembly
GCA_000006295.1
Location
NW:298824-302685[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00044 0.03 14.1 0.4 1 23 315 337 315 337 0.98
2 10 0.00017 0.011 15.4 3.2 1 23 351 373 351 373 0.98
3 10 0.011 0.71 9.8 0.2 3 23 502 523 500 523 0.92
4 10 0.0023 0.15 11.8 1.5 1 23 593 616 593 616 0.94
5 10 0.0011 0.075 12.8 4.9 2 23 641 662 640 662 0.96
6 10 5.7e-05 0.0038 16.9 0.8 1 23 668 690 668 690 0.98
7 10 0.00016 0.01 15.5 2.3 1 19 696 714 696 719 0.91
8 10 2.2e-07 1.5e-05 24.5 0.9 1 23 725 747 725 747 0.98
9 10 2.1e-06 0.00014 21.4 2.2 1 23 753 775 753 775 0.99
10 10 3.7e-07 2.5e-05 23.8 0.7 1 23 781 803 781 803 0.97

Sequence Information

Coding Sequence
atgGAAGAAACTTCAACTGACAAAAGTAAAGATCAACACCAACCTCAGGAGCAATCACAATCCCAGACACATCAACAGCAACATCATGAGCCGCAACATAACTCTCCCTCTTACAACAATGCTGTTAAAGAAGCAGAAGCTCATGCACTGAGGGATCATAATGTTGGAAGAGAAGTAACTAAAACTTCAGTCGAATCTGAAGATTTAATGTCATCTCAgtttataaatattcaaaGAGTTCCCGATGTAGTGACAACCAAAAATTTCTTATCCAATTCGACATTATTATCAGGGAATGAGCTTTTAGTTGATATTAATGGCGATTTAATATCTAGCGGCTCTATAGCATTAGAAAGATTTATTCCGCATCAGTATGAGGATGATTTACTTCACGATGATTTAACTGAAGATGATAAAAGATTAGCAGCAGCTTTGGTTGCAGTACAATTAGTgacacaacaaaaacaacaatctGGTGAAGAAACAACTTTACCCCCTTTGCCTCCgcttaaaaaagttttgagtAAAAATCGTTACTTACGTCCTCACTACAATCAATTAAACACATCTGAAATAGATCAGCAGACACAATTAGCCAGTTTAGGACTTCACACTGAAGGAGAACATATAGAAATATCAACTGAAGAAATAGAAATTGGGCCAAACGAAGTAATAAAAACTGAACTGAATGATTTTATCATCGAAGAAGATGCTAACATTAAAACGGAGGCATGTGATGAGAGTGAACAATTGAGTGATGATGAACAGGATAGTGATGAAGGATTGCATGATTctgattttgaaaatgatagagaaaaatcgaaaaataatttgccTCACAAGAAAAGAATATCgagaaaacttaaaaatactCAGAAAAATGCAAATGCTAGAACTTTAAGCCACGATGAGCAAAACATACAGTTGGTGAAAATTAACAGTTACAAGTGTAACAAGTGTTctgaattttttccaaatgcGAATGCATTCGCAATTCACAAAGCGAcacataatataaaaaaaccatCTGGAGTTAATCAATCTTCGTCATTTTCATGTGAgctttgttttaaaacttttactaaccaatggaaattttttgaacATTTAAAATCACATTATGAGCCATTAGAATTAGATACAAATTCTCCTAAACGAACTTTGCCTTCAGGAACTAAACAAAATTCAAACATAAATGaagttattgtaaaaaaagaattgaaaaacagCGGGATAAAAGTAAGAACTTTACAAAATACAACTTCATTATCACCAAATGCTAAAATCGGTTCTgTAAAAGCCAAATCACCGGTTACCATTAATCAAACGACAACTCTACAGACTGTTGCCAAATGGCCATCTCCTTCCCCGTCTTCGGCATCCTCGTCACCCTCTCCGGCAGCTACACAACCACAAACCCAAGAAATAAATACATCTTCATCCACTGCATCAATATTGTATCAACATTTAACGCAAAATCAAACGGAACAAATATTATGGAATTGCGAACCTTGTAAAAGAATATTTCGCAGACAAGAAACGTACGAAAGTCATTTGAGCGTGGCACATCCCAAACAAGAAGAAATAGAAGAATTCAGCGAGCCCGAAGACATGATGGAAGGGATAAGTGTTGAAGTTCACAGTGACGACGATAAGGAAACaacagaaaaaGATAACACGATTCAAAAAGAATGGTACAGAGAAGAAGATTTACACGCGGCCGAAGCTGATTTACAAGAAATGGAAGAAAGGACGAAAACGGTTTATGTCGATGCTCACATGTGCGAAATGTGTAACGAAGCCTATCATTCGAAAGCAGCTCTCAATCAACATATATCTCAACAGCACGCAGAACTAATGACCGCCATAACTAAAACCGTTAGGAGGCAACCCGACAACACGGCAAAAAAGGGTAATTTGCACTGTAAGGAATGCGGAAGGTATTTCAATCATAGAAATTCTCTCGTTTATCATTTGAAAAGTCATCTCGGAGAAAGGCCTCATCAGTGTGAAGTTtgcggaaaaggttttttcgcAACGAATGCTTTGAAGGTACACATGAGGCAGCATTCAGGCGTGAAACCGTTTAAATGTGAATTTTGCGGTAGGAATTTCAGACAGTGGGGagatttaaaatatcattGTATTTCGATACATTCTGATCAGAAAAATTTCCAATGCGAATATTGCGGTAAAGATTTTGCGAGAAAATATTCATTGACGGTTCATTCGCGAATACACACGGGAGAAAGGAATTACAAATGTGAATTTTGCGAAAAAAGTTTCAGAGCTTCGTCGTACCTTCAGAATCACAGGAGGATACACACGGgtGAAAAACCTCATCCCTGCGATGTTTGCGGGAAACCGTTCAGGGTTAGATCAGACATGAAAAGGCACATGATAACTCACAGTAAAGAACCGTATTCGACGTTTGTCATGAAAATCAAAAGAGAACCGCAAACGCCATCGAATAACGACGATAACAAATTAATAGTTCAGCAGGTCGACGAACCCATTCCCGAAATATCTAAAGTTGAAGAGCTGGAAGTGAGCACGGTCGAAAGTATATTGCCGGACGAAGCCGTGACTGCATCCAGTAGACTTCAAGAAGAATTATCAGTTACTTATGCCGAGAGAGATCCATTAGAGACTGCCGGAAGAGAAGCCAACACTTTATACGTTTGGCCCGTGTACACGACGTAG
Protein Sequence
MEETSTDKSKDQHQPQEQSQSQTHQQQHHEPQHNSPSYNNAVKEAEAHALRDHNVGREVTKTSVESEDLMSSQFINIQRVPDVVTTKNFLSNSTLLSGNELLVDINGDLISSGSIALERFIPHQYEDDLLHDDLTEDDKRLAAALVAVQLVTQQKQQSGEETTLPPLPPLKKVLSKNRYLRPHYNQLNTSEIDQQTQLASLGLHTEGEHIEISTEEIEIGPNEVIKTELNDFIIEEDANIKTEACDESEQLSDDEQDSDEGLHDSDFENDREKSKNNLPHKKRISRKLKNTQKNANARTLSHDEQNIQLVKINSYKCNKCSEFFPNANAFAIHKATHNIKKPSGVNQSSSFSCELCFKTFTNQWKFFEHLKSHYEPLELDTNSPKRTLPSGTKQNSNINEVIVKKELKNSGIKVRTLQNTTSLSPNAKIGSVKAKSPVTINQTTTLQTVAKWPSPSPSSASSSPSPAATQPQTQEINTSSSTASILYQHLTQNQTEQILWNCEPCKRIFRRQETYESHLSVAHPKQEEIEEFSEPEDMMEGISVEVHSDDDKETTEKDNTIQKEWYREEDLHAAEADLQEMEERTKTVYVDAHMCEMCNEAYHSKAALNQHISQQHAELMTAITKTVRRQPDNTAKKGNLHCKECGRYFNHRNSLVYHLKSHLGERPHQCEVCGKGFFATNALKVHMRQHSGVKPFKCEFCGRNFRQWGDLKYHCISIHSDQKNFQCEYCGKDFARKYSLTVHSRIHTGERNYKCEFCEKSFRASSYLQNHRRIHTGEKPHPCDVCGKPFRVRSDMKRHMITHSKEPYSTFVMKIKREPQTPSNNDDNKLIVQQVDEPIPEISKVEELEVSTVESILPDEAVTASSRLQEELSVTYAERDPLETAGREANTLYVWPVYTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-