Phum007764.1
Basic Information
- Insect
- Pediculus humanus
- Gene Symbol
- -
- Assembly
- GCA_000006295.1
- Location
- NW:178125-180937[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0059 0.4 10.6 2.4 1 23 207 229 207 229 0.98 2 15 0.64 43 4.2 1.0 2 22 235 255 234 255 0.93 3 15 0.00017 0.011 15.4 2.8 2 23 264 285 263 285 0.96 4 15 0.00038 0.025 14.3 1.0 3 23 290 311 289 311 0.95 5 15 0.096 6.4 6.7 0.8 2 23 322 344 321 344 0.94 6 15 0.85 57 3.8 0.2 1 23 349 371 349 371 0.95 7 15 0.019 1.3 9.0 1.5 2 23 378 399 377 399 0.91 8 15 0.0013 0.089 12.6 0.7 1 23 404 427 404 427 0.95 9 15 2.1e-06 0.00014 21.4 1.5 1 23 436 458 436 458 0.98 10 15 5.5e-05 0.0037 16.9 2.6 1 23 464 488 464 488 0.91 11 15 6.9e-06 0.00046 19.8 0.4 2 23 510 531 509 531 0.96 12 15 1.7e-07 1.1e-05 24.9 1.3 1 23 535 557 535 557 0.98 13 15 7.7e-05 0.0052 16.5 0.1 2 23 564 586 563 586 0.96 14 15 6.5e-08 4.3e-06 26.2 2.8 2 23 593 614 593 614 0.97 15 15 0.00041 0.028 14.2 3.8 6 23 624 642 622 642 0.96
Sequence Information
- Coding Sequence
- atggacttaaatacaattaaaaaacaaGTACAAGCAATGTTGCAGTCTGTTCTCTCTTTAGACTCAACAGGTCGAACAGAAGTAATGGGATATTTAAAAGAATGTGCTTTAAATTATGGTTTAGTCATTCCCAATGAAAAAGAAGGAATTAACtgtaataatattacaaaGTCATACAGTTCAGACGATAATGTTTCTACGATTTGTCAAATCGAAAACACTCCTACAATCGAAGACAAAAACTGTGATTCTAATAGTGATGAATGTAATTTGGTGGATAATGACATGTGTTCAAATTTGAATGAAAGTGAAATTCTACatgataatgtaaattttaataattttactcaaTTACTTAAAGAtgttgataatgatattaCGAGTAGTTCTCTCATTGAAAAGACAAACGTAAAAGAGTGCcttaatgaaaatgaaaatgtagaAAAACACCAAAATTCGAATAATCAAACATTAATTTCTGACAAAATGGATTCAactaaatcaataaattataaaaatttattaaatgataaaaaagaaaataaattattaaaaaagaagccTGCTAGGAAAAAAAGACATGTCGATACTGATTatgtagaaaatgaaaatagtaTATTTAAATGTCCTGGATGTATGACTACATGCGAGACTAAATCGGCTTTGTTGCAGCATTTTACAACTCATGGCAAATCTCCCTTATCGTGTAAATTATGTAGATCAACATTTAacagtattttattattttggaagcatcagaaaaaaaaagaatgcaaATTATCATTGTTAAAATGTTCCGAAtgtgatgaaaaatttaagtatcgaagacattatttaaaacacaTATTGggtcataatgataataattgtaggTACTGCGAAGAAAAATTTAGCACGTGGGCactttataaaaatcatttaaaagaaaaacatccgGATATTAAAATGGAAAGGGATTTAATACCTTGCAGATTTTGTGCCATGAGTTTTCGACGTCATTTAGGTTTATACAATCATTATCAAGTAGAACATTCCAAAgggaaatttgtttgtttgtcctgCGGTTTGTTACTGcctacaaaagaaaaatttaaagagcaTTCGCTTGTTCACGAATccgaaaaaatttggaaatgtAAAATATGTAAAATGAAGTTTTACAGGAGGCAACAATTATTGTTTCACGTTTCGGTTCACAAATCGGGTACTTATAAATGCTTGACTTGCGACATAACGGTAACTTCAAAAGTTGATTTGTACAAGCACAAAAAAGATGGTCACGAAGTTAAAGGTCCAGAACCGAAATTCGAATGCGAAATATGTcataaagtatttaaaaaaaatgtcgttttaaaaaatcacatgGCGACTCattcattggaaaaaaaatattattgtaaatattgCGTGAAGAGTTTTAGAACCATGGACGCATTGCAAAAACATGAGAAAAGGAAATCGCATTTTGAAAAAGCCAAGATAATACTCCCCGAGAGCAAGTACGAAAAAGTTTACGAAGATAAATTAATATGCGAAAGCTGTggaaaacaatacaaaacTCAACGTGAATTGACGTGGCACTTGAGAGTTCACAAGAGCATTTACGAATGTGACGAATGCAAGAAAACATTTACGTTGAAAGTTAATTTGACCAAACACATACGATTGCACAGGAATAAAGTTTGCGTCGTTTGCGAATTGTGCGGCAATACTTTCAATCAATTATCAGCATTGAACGAACACATATTAATGAAACATTCGGATGTGCGAAATGCCGAGTGTCaagtgtgcaaaaaaaaattcaagagaAAAAGCGAATTGAACAGGCACATGAGAATACACGAGCAAAAAAGGCCGTTCGTGTGTTTTTGCGGCACGGCTTTCAAACAATCGAGTCACTTGCAAACCCATTACAAAACGTTTCACGAGaaaaacaatcatcatcaaaacaatttgatgcaacctgaaaattttccccAACATCCGGGAAACGGAGGAGTTTACGACGGAACGATAAACGATCGTTCGAAATCGCAAATGTACGTCAGCAACGGCGACGAACAAGGCGGAGGAGAATTATTATCCCTCGAAAACCTCGAAACGGATTTCAGGAATGCGAATACGTTCGACGAAATACAAGTGAACGGAAATCTCGAAACGAACGCATACGGATTAAGGTACCCGCACGAGGGAGACATGGATCCGATAAACGTGACTTACGAAGAACTCAATTTCGATTCGGGTCAATCGGATAAAAGGGAATTAGTTTTCACAACGTCTCCTGCCATAGATTTGAGCATGGTCACAATATCGGAAGTTGTAGAAAATGGAATGACACTCGAAGAGGAAAGGGAAATCGTGGAATCAGTGGAATCATTCAACAAACTTCCGGACGATGCATCCAATTTACAATTGGTTAATTTAAGCGATCACATTGTTcaagaatatttattaaacctTCCGTGA
- Protein Sequence
- MDLNTIKKQVQAMLQSVLSLDSTGRTEVMGYLKECALNYGLVIPNEKEGINCNNITKSYSSDDNVSTICQIENTPTIEDKNCDSNSDECNLVDNDMCSNLNESEILHDNVNFNNFTQLLKDVDNDITSSSLIEKTNVKECLNENENVEKHQNSNNQTLISDKMDSTKSINYKNLLNDKKENKLLKKKPARKKRHVDTDYVENENSIFKCPGCMTTCETKSALLQHFTTHGKSPLSCKLCRSTFNSILLFWKHQKKKECKLSLLKCSECDEKFKYRRHYLKHILGHNDNNCRYCEEKFSTWALYKNHLKEKHPDIKMERDLIPCRFCAMSFRRHLGLYNHYQVEHSKGKFVCLSCGLLLPTKEKFKEHSLVHESEKIWKCKICKMKFYRRQQLLFHVSVHKSGTYKCLTCDITVTSKVDLYKHKKDGHEVKGPEPKFECEICHKVFKKNVVLKNHMATHSLEKKYYCKYCVKSFRTMDALQKHEKRKSHFEKAKIILPESKYEKVYEDKLICESCGKQYKTQRELTWHLRVHKSIYECDECKKTFTLKVNLTKHIRLHRNKVCVVCELCGNTFNQLSALNEHILMKHSDVRNAECQVCKKKFKRKSELNRHMRIHEQKRPFVCFCGTAFKQSSHLQTHYKTFHEKNNHHQNNLMQPENFPQHPGNGGVYDGTINDRSKSQMYVSNGDEQGGGELLSLENLETDFRNANTFDEIQVNGNLETNAYGLRYPHEGDMDPINVTYEELNFDSGQSDKRELVFTTSPAIDLSMVTISEVVENGMTLEEEREIVESVESFNKLPDDASNLQLVNLSDHIVQEYLLNLP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -