Phum002507.1
Basic Information
- Insect
- Pediculus humanus
- Gene Symbol
- -
- Assembly
- GCA_000006295.1
- Location
- NW:300235-303006[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.00015 0.01 15.6 1.2 1 23 72 95 72 95 0.92 2 15 0.0017 0.11 12.3 2.4 2 23 100 121 99 121 0.96 3 15 0.00047 0.032 14.0 0.6 1 23 147 169 147 169 0.96 4 15 0.013 0.86 9.5 0.1 1 20 175 194 175 196 0.95 5 15 0.014 0.94 9.4 0.2 1 23 205 228 205 228 0.91 6 15 0.00013 0.0088 15.8 1.0 1 23 231 253 231 253 0.97 7 15 0.0028 0.19 11.6 4.2 1 23 265 287 265 287 0.97 8 15 0.00015 0.01 15.6 0.1 2 23 294 316 293 316 0.95 9 15 0.0038 0.25 11.2 1.7 3 23 321 341 319 341 0.95 10 15 2.5e-05 0.0017 18.0 1.4 1 23 349 371 349 371 0.97 11 15 0.003 0.2 11.5 0.3 1 23 377 399 377 399 0.96 12 15 7.2e-06 0.00048 19.7 0.7 1 23 405 427 405 427 0.98 13 15 5.2e-06 0.00035 20.2 4.2 1 23 433 455 433 455 0.99 14 15 7.6e-06 0.00051 19.7 1.1 1 23 461 483 461 483 0.98 15 15 0.00035 0.024 14.4 1.2 1 23 489 512 489 512 0.97
Sequence Information
- Coding Sequence
- ATGGAATTTGCTTTAGTTCGAGATGGTGAAATCGAAGAAGATCCTGAACCTCAAACGAAAAGGCTGAAACAAGGAAACAGAACTATTCGATTTCGTGCTATAAAACCCAAACCTCCTGGTTCTGTTCAGTTATTGAAATGTCAATCGTGTAATTTTATAACAACTGAACAAGACCTTTTGTCTTGTCACAGATTGGTATGCAGTGCAATGGCTTATAAATGTACAATGtgcgataaaaaatttgatagtCAAAAAATGATCAGGAATCATAAAATAGAAGCTCATTTGACAAAGTGGATATGTCATTTTTGTAACATAAGTTTtaacgaagagaaaaaatttacagtgCATATGAAAAATCATTTGGGAGATAGATTGAATAgtaaaacgattaaaacaaaagtcgaggaatgtaaaaaagaaaaagctgtACTCACTTTTAAATGTCCACATTGCGCGGAAAGTTTTGAAGCTTTCAGTCAACTTCAAATTCATTTAGTCAATCACACGAGTTCTGTTACCTTTAAGTGCGTGCGGTGCGATATTGGTTTTCAAAATAAACTCGAATTAATAAATCACATAAGTGATTTGCAAGAAGGACAGggtaaaacgtttgtttgcgCGGAATGTTCTTTTTCAACGTCCACGCTCGCCGCATTAAAACAACATTTCGTGTCGGCTCACGAAGCCTTCAAGTGTTGGATAtgcaagaaaaattttcaaatggacGAGTTGAAAAAGCATTTGGCGACGGAACACGGTGCCAATGCTGTCACGCTCCAATCTAAAAGCTACACCTGCGTGCATTGCTCGGAAAAATTCACAAACAGGAGAGCTTTACACTTGCACGAAATCAAACACCCGGAAAATTTGAACATACAGTGTCCCGATTGCGGTGAAAAATTTGCAAGAGATAAATTTCTCAACGAACACAGGGAAGTCGCGCACACGGTCTCACATTGCAGAGTGTGCAATAAAGCATTTGGAAacgtaaaacaattaaaatcccACGAGGCTCGTCACGCGAAAAGTGATAAAACTCAATTTAAGTGCACGGACTGCGATAGAATATTTCAAACACCCACAGGATTACGTCATCACAAGGCCATACACACGGGAGAATTCAAATACAAATGCGAATTTTGCGGAAAAGGATTCGTGGCGAGAGTTCGATACGAAGAACACAGAGCATCACATACTAAAGAAGAACGTTACTCGTGTGAAATTtgcggtaaaaaattttcttttcaagcCACTTATTGGATTCACAGAAAGTGGCACGACAATCCCACTCCCTACAAGTGCGAATATTGCGGACGATTGTTTAAACATTCTTCTCTCCTGTCGGTTCACAAGAGAAAACACACCGGCGAACGACCCTACGAATGCCCTCACTGCGATCAATCTTTCACCGTGGGAAACACTCTCAAACGTCACTTGATGTTGCACACGGGAGTGTTTCCATTCACATGTCAAATATGCGATCAAGGATTTTCCGGAAAGCATAAAATGGCGTTGCACATGAGTAAAGTTCACAACGACAATTCTCTCCTGGGACagcaaacgcaaaaaaaaccgACCGAGTACAAAATGGTTGTCAAAGACACGAAAAAATCGGAAGTCGATGCGACGTTACAAAATCAAACGTGGGTTTTGAAAGAAAACGACAACAGCGGATCTCAGATGTTGACCATACAAACGGAAGAAGGGGAAAACATTCCTTGCACTTTGCTCACGGACGACATGATTGGAAACATTGTCAACACGAATAATAGAATCGTTGAAATAATACCCTACGATTCGATAAAAGGAGAAGACGACGTGGACGACGAGGGAAACGAAGTCGGTTTCATACTCATGAATCAAACGGATGAATCCGCACTCGGAATTGTCAACAACAACGAAGATGAAGATTTCAAAGATTCTTCCACTCATGGATATAACGGAGAATGTACCAAAGTGGATATCGACTCCGTGGAAGGTATGGATTCTGGAAATTCTCAATCTCAACCGTGTGACAGTTTCGTTAAAGTCGAACATGTCGATGTCAAAGAAGGATCCATGGAATCCGTTGAAAACATGAGCGAAGAATTCGTTTCCGTATTATAG
- Protein Sequence
- MEFALVRDGEIEEDPEPQTKRLKQGNRTIRFRAIKPKPPGSVQLLKCQSCNFITTEQDLLSCHRLVCSAMAYKCTMCDKKFDSQKMIRNHKIEAHLTKWICHFCNISFNEEKKFTVHMKNHLGDRLNSKTIKTKVEECKKEKAVLTFKCPHCAESFEAFSQLQIHLVNHTSSVTFKCVRCDIGFQNKLELINHISDLQEGQGKTFVCAECSFSTSTLAALKQHFVSAHEAFKCWICKKNFQMDELKKHLATEHGANAVTLQSKSYTCVHCSEKFTNRRALHLHEIKHPENLNIQCPDCGEKFARDKFLNEHREVAHTVSHCRVCNKAFGNVKQLKSHEARHAKSDKTQFKCTDCDRIFQTPTGLRHHKAIHTGEFKYKCEFCGKGFVARVRYEEHRASHTKEERYSCEICGKKFSFQATYWIHRKWHDNPTPYKCEYCGRLFKHSSLLSVHKRKHTGERPYECPHCDQSFTVGNTLKRHLMLHTGVFPFTCQICDQGFSGKHKMALHMSKVHNDNSLLGQQTQKKPTEYKMVVKDTKKSEVDATLQNQTWVLKENDNSGSQMLTIQTEEGENIPCTLLTDDMIGNIVNTNNRIVEIIPYDSIKGEDDVDDEGNEVGFILMNQTDESALGIVNNNEDEDFKDSSTHGYNGECTKVDIDSVEGMDSGNSQSQPCDSFVKVEHVDVKEGSMESVENMSEEFVSVL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -