Phum007646.1
Basic Information
- Insect
- Pediculus humanus
- Gene Symbol
- -
- Assembly
- GCA_000006295.1
- Location
- NW:57708-60768[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.0017 0.11 12.3 1.8 2 23 194 215 193 216 0.94 2 17 0.0012 0.078 12.8 1.1 2 23 222 244 221 244 0.95 3 17 0.00088 0.059 13.2 0.4 2 23 251 272 250 272 0.96 4 17 1.4e-05 0.00093 18.8 2.7 1 23 278 300 278 301 0.95 5 17 6e-06 0.0004 20.0 1.6 1 23 308 330 308 330 0.98 6 17 7.9e-05 0.0053 16.5 1.6 1 23 336 359 336 359 0.97 7 17 2.6e-05 0.0017 18.0 3.8 1 23 365 388 365 388 0.94 8 17 0.0003 0.02 14.6 0.7 2 19 396 413 395 416 0.93 9 17 2.1 1.4e+02 2.5 2.3 1 23 440 463 440 463 0.87 10 17 0.024 1.6 8.6 2.1 3 23 469 489 468 489 0.98 11 17 1.3e-07 8.4e-06 25.3 2.6 1 23 495 517 495 517 0.98 12 17 6.4e-07 4.3e-05 23.0 0.7 2 23 524 545 523 545 0.96 13 17 0.056 3.8 7.5 4.7 1 23 551 573 551 573 0.96 14 17 1.5e-06 0.0001 21.9 0.7 2 23 580 601 579 601 0.96 15 17 0.37 25 4.9 3.8 1 23 607 630 607 630 0.96 16 17 0.00028 0.019 14.7 0.5 1 23 636 658 636 658 0.98 17 17 0.16 11 6.0 11.8 1 20 664 683 664 685 0.93
Sequence Information
- Coding Sequence
- ATGTGCAATAATATACATAGAGTTTGGATACAAAAGGGAATaaaAGTAaaaaacgaagaaaatgtCGGTGGTAGTAAATTCAAGCTTTATTCTTTGCTCAGtctcgaaacgaaaaaatcaaCGGGAACATTAaacgatttggaaaaaaatgatggatttgagggggaaaaaataaaagaaaataataggGAAATAGTAGATGGTGACGTCGTcaacgatgatgacgtaaatgaTAGGAggatcgtggaagaagaaacggaaaatttcGATGAGTCGATGTCGTTTGATGATGAGAAAATATTAATGgacaaaaggaaaacgatCGATTCGAGGGATAAAGATTTTTCATCGTCGGATGATGATTTGACATTaACGATTAAAATACAATCGAacatggaggaggaggaggaggacgacgacgacagttTCGAAATTGTCGAAACGGGTATCGATACGTCAGTAGTGGATTCAAAAAATGGGGATAAGAAAAAGGTTAAGAGTAGAAAAACTCAAACTCTTGGGGAACAAACAAAtccggcgaaaaaaaaaaggtttagaaTTCGTCCGGCCGTACCGAGTTCTTGCACACTTTGCGACAAAGTTTACAAAAATGGTGAAATATTAAGGCAACACATGAAAAGTCATCACGTGACCGGAACCATAGAGTGTCCGAGTTGCAAATTAACTTTTACCTCGCTGAGAAGTTTAAAATATCACGAACAACGTAAGCACAGCAATTTGGAACCCGTGCCTTGTTCGTTTTGCGGTAAAAAGTTTCTGGATAAAAAGTACCTGAGAATCCACGAAAACATACACAGTCAAACGAATCATTTCGTCTGTCAATTTTGCGGTAGGAAATtcataatgaaaacaaatttgacCGTACACATAAGTCGTCATCACacgaaaaaatcaaacgatttCGTTTGTCAGATATGCGGAAAAGCTTTCCCATTCAAATTGtatttgaaaaaacatttcaaaactCACACGGATGACAAACCCTACGAGTGTAACCACTGCGAAGCGAAATTTCGAGAAAATACTTTGCTTCGAAAACACGTCAACAGCATACATTTGAAATTGAGACCTTTCCTATGTCAATACTGTCACAAAACTTTCACCCGAAGTTTGTACCTGAGAGAACACATGGAATCGCAACATTTGGGAATACAAAGAAAACTCGAATGTACGAAATGCGGGGAAACTTTTACAAATAGAAACAGGTTGAGGCAACACGAATttaggaaaaaaagaaagttaaatTATTTGGACGTTACATACGATTATCCGGTACCGACGAAAGATGGTAAAGTTCATCAATGTCGAATATGtagaaaatatttgaaaaacgtAACGACGAGAAATAGACACGAAATTGAAAATCATCCGCCTCCGCACGGTTGCGAATTTTGtcaaaaaacatttacaacGGTTTTAACGTATCACATACACAGAAACATACATCTCGGTTTGACTaaatataaatgtaaatattgCGGCAAACATTTTGCTTCCCGTTCGAATTTAGAAGATCACGAAAAAGTACACACGAAAGAAAGGCCCGTGGAATGTCCGAAATGTGATAAAAAATTCTCATCCGTATCGAATCTTCGCgttcatttgaaatttcacGACAACGTTAAAACTCACTTCTGTCACGTTTGCGGCAAAGGTCACGTGACAATGGGTAATCTCAAGTTACACGTCAAAAGGCATACGAACGAAAGAAATGACGTGTGTCACATATGCGGCAAAGGTTTTAACGGCAAAACCGAATTGAAAAAACACATTGAAAGTCATAgcgcggaaaaaaaattttcttgtcaGTATTGTTgtcaaaaattgaaaaccgTTAATTCGTTAAAAAGACACGTTAATATACAACATTTGAAATTGAAACCTTATAAATGCGATTTGTGTTTAAAAGATTTTGGaagattggaaaattttaaagaacaCGTACAAATCCACGagatgaaaaaacaatttttttgccaCGGATGTCATAAACAATTTACTAATTCGAAACATTTTCATTCTCACAAATGTCAAATTTGa
- Protein Sequence
- MCNNIHRVWIQKGIKVKNEENVGGSKFKLYSLLSLETKKSTGTLNDLEKNDGFEGEKIKENNREIVDGDVVNDDDVNDRRIVEEETENFDESMSFDDEKILMDKRKTIDSRDKDFSSSDDDLTLTIKIQSNMEEEEEDDDDSFEIVETGIDTSVVDSKNGDKKKVKSRKTQTLGEQTNPAKKKRFRIRPAVPSSCTLCDKVYKNGEILRQHMKSHHVTGTIECPSCKLTFTSLRSLKYHEQRKHSNLEPVPCSFCGKKFLDKKYLRIHENIHSQTNHFVCQFCGRKFIMKTNLTVHISRHHTKKSNDFVCQICGKAFPFKLYLKKHFKTHTDDKPYECNHCEAKFRENTLLRKHVNSIHLKLRPFLCQYCHKTFTRSLYLREHMESQHLGIQRKLECTKCGETFTNRNRLRQHEFRKKRKLNYLDVTYDYPVPTKDGKVHQCRICRKYLKNVTTRNRHEIENHPPPHGCEFCQKTFTTVLTYHIHRNIHLGLTKYKCKYCGKHFASRSNLEDHEKVHTKERPVECPKCDKKFSSVSNLRVHLKFHDNVKTHFCHVCGKGHVTMGNLKLHVKRHTNERNDVCHICGKGFNGKTELKKHIESHSAEKKFSCQYCCQKLKTVNSLKRHVNIQHLKLKPYKCDLCLKDFGRLENFKEHVQIHEMKKQFFCHGCHKQFTNSKHFHSHKCQI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -