Phum001344.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pediculus humanus
Gene Symbol
ken
Assembly
GCA_000006295.1
Location
NW:442955-445576[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 8.7 5.9e+02 0.6 0.1 2 10 373 381 372 385 0.86
2 13 0.011 0.73 9.7 3.3 3 20 485 502 483 505 0.92
3 13 1.5e-05 0.00098 18.8 0.2 1 23 511 533 511 533 0.97
4 13 9.2e-08 6.1e-06 25.7 1.4 1 23 539 561 539 561 0.99
5 13 9.2e-07 6.2e-05 22.5 0.7 1 23 567 589 567 589 0.99
6 13 1.1e-05 0.00075 19.1 0.3 2 21 595 614 594 615 0.94
7 13 0.00069 0.046 13.5 0.8 2 23 623 645 622 645 0.90
8 13 1.4e-07 9.7e-06 25.1 1.2 1 23 651 673 651 673 0.98
9 13 9.4e-05 0.0063 16.2 7.7 1 23 679 701 679 701 0.99
10 13 2.8e-06 0.00019 21.0 2.6 2 23 708 729 707 729 0.96
11 13 7.9e-06 0.00053 19.6 1.8 1 23 735 757 735 757 0.99
12 13 0.099 6.7 6.7 0.3 2 23 765 784 764 784 0.75
13 13 4.4e-06 0.0003 20.4 2.7 1 23 790 813 790 813 0.97

Sequence Information

Coding Sequence
ATGAATTCGCCCCAAGAATCAGGTTTTAGAGCTTTTCAAGGTACTGATTGTGGATGGTCTTCTTGCTGTAGAAATTCAACTCATTATCATTGTAGAACTTGCGGTTATGGAACAAATCTTCATCAAAAAGAATTCCCTAAGTTATCTTCTTCAACGGATTCAAGTTTAATGCAACATGAAGTTCATCAAACAACccaaccttattattattcttctatTAGTCCAACACTACCTGTTCCACCTCAATCGAACAATTCATCAAGTTCAAATGTCAAATTACTCTCAAATCAGTCTGGTGCAATGTTTAACTTTGTAATTCCTCCACAAAATTCACAGTACAGTTCAATTTATGGAACACAAACTGTCTTTCCTAATTCCAATTTGTTCTCCCCATCAAGTTTTAATAGTTTCAATCAAATTGATTCACCTTGGTTACCACAAAATAGATTCATACCACCAGGTGTACATTCATCTAATTCGACATCTGACTTGTTAGGAAGCGGAAAAAGTCCTTTTGATAAAATTGAAGCATCAAATTCTCCTTCTTGTTTTGGGAGAATGAGTAGTATtgaaactactactactatagGAATGTGTTCTCCTCTCACAGCTGAAGCATATAAAGTAGTTTCTAAAgaatttcaaacaaaattaGATTCTCAAAGTTGGTATTGTAGTCCATCAAATGCTTTGAACTATAACAGTCAATCTTCATCATCATGTAAATTTAGCGAAACTTCCCCATCATGCTCTgttagtttattattactgGAATCAAAtgatcaaaaacaaaatcaagactattcaaatgatgataatttaacttttgaaTCATCAAGAAATGAtgttaaaactaatttaaataaggaaaatacaaaaaattatacttcTTGCATGAATATGCCCAGACAAGATCttgatgtttataaaaatgaattagaagaaaagaaaaattcatcgcaatcgataaatttaagttcaagtaataaagaaaatgttgaATTTGAATCACTTTCTACATCAGAAGAAAGTGACATAATTGTTGAAGAATCTGATTCTGAAAATGTTAATTCTACAAGCGATTTAGAAAGTGATGTTAAAATGGTTATATCGTCAAAATGTTTAGTTTGTAATAAATCTTCTTCTGTTGATTCAGAAAATGATTTTGTCAAAATTAGTAAAGAAATGCCTGTAACAACATCAACTCAAGTTTCAATTTTAAGCAAACTTTCACAAGTAAttaacgatgaaaattttaaaaagttgaaagGTTGCATTATATGCCCGAggtgtttaaatttaattaatgtggTCGATCAactggaaataaaattaaaatcggctAAGAAAGAATTGGTCGACATCTATAAGTCTAAAAATTCAACCAATGATATATCTGATCAAAAAATCGAACAACAATCTTCtgatgaattaataaaaaaaaaattattttgtgatGTTTGcaataaacaattttctactattaattatttagaaaaacataaacaatgtCACACTAAAGTATTCAGTTATTATTGTGAATATTGTGGTAAAGGTTTTGCAGTTTTACAAACTCTTCAAAACCACATTTCTCTTCATTCCAATTCCTCAAGGTTTCAATGTGAACTTTGCGGTAAAagatttatacaaaaaaataatttgactgATCACATAAAAAAGCACAAAGGTGAATATAAATACAAATGTGGGATTTGTAACAAAGGATTTATAAGAAGAAGTGTACTTAAAACACACATGTTGTCTCACAATTCTGATTCATTGATGTGCCAACATTGTGGaaagcaatttaaaaatttagcaAATTTATCGGTTCATATAAAAATATGTTCGggagatttaaaatttgactgcataaaatgtgataaaaaatttccaatcaaatcattacttaaaaaacatatttcaATTAGGCATAATTcagaatttcattttgtttgcaACATTTGTAAAAAgggttttgcaaaaaaatcaGATTTAAAAACTCACATGAATTCGCATTCAGAAAACAGACCATTTAAATGTTCTAAATGTAATTGCTGTTACAAGAGTTTGAGTAATTTGAATCAGCATTTAAAAGTTCATTCCGTTTATGGAGTATTGGAGTGCAAAGTTTGCggcaaaaaatttacaaggcAAGATTGTTTGAATGATCATTTGAATCAGCACACTGGAAATAAACCGTACAAATGCACAACCTGTTGGAAAACTTTTGCAAacagaataaattttaacatacATGTTAAAAGGCATAATGGAACTCTTAAACAAACTCCTTGTCCCATCTGtggtaaattatttacaaaaggtTTAAAAGATCATTTAACATCACATTCTGGACAAAAACCATATTCTTGTAAACATTGTACTGCAGTGTTTACTGTGAAAAGTAGTCTCAATAAACATATTAAAGTAAAGCAcaataatttgtaa
Protein Sequence
MNSPQESGFRAFQGTDCGWSSCCRNSTHYHCRTCGYGTNLHQKEFPKLSSSTDSSLMQHEVHQTTQPYYYSSISPTLPVPPQSNNSSSSNVKLLSNQSGAMFNFVIPPQNSQYSSIYGTQTVFPNSNLFSPSSFNSFNQIDSPWLPQNRFIPPGVHSSNSTSDLLGSGKSPFDKIEASNSPSCFGRMSSIETTTTIGMCSPLTAEAYKVVSKEFQTKLDSQSWYCSPSNALNYNSQSSSSCKFSETSPSCSVSLLLLESNDQKQNQDYSNDDNLTFESSRNDVKTNLNKENTKNYTSCMNMPRQDLDVYKNELEEKKNSSQSINLSSSNKENVEFESLSTSEESDIIVEESDSENVNSTSDLESDVKMVISSKCLVCNKSSSVDSENDFVKISKEMPVTTSTQVSILSKLSQVINDENFKKLKGCIICPRCLNLINVVDQLEIKLKSAKKELVDIYKSKNSTNDISDQKIEQQSSDELIKKKLFCDVCNKQFSTINYLEKHKQCHTKVFSYYCEYCGKGFAVLQTLQNHISLHSNSSRFQCELCGKRFIQKNNLTDHIKKHKGEYKYKCGICNKGFIRRSVLKTHMLSHNSDSLMCQHCGKQFKNLANLSVHIKICSGDLKFDCIKCDKKFPIKSLLKKHISIRHNSEFHFVCNICKKGFAKKSDLKTHMNSHSENRPFKCSKCNCCYKSLSNLNQHLKVHSVYGVLECKVCGKKFTRQDCLNDHLNQHTGNKPYKCTTCWKTFANRINFNIHVKRHNGTLKQTPCPICGKLFTKGLKDHLTSHSGQKPYSCKHCTAVFTVKSSLNKHIKVKHNNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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