Basic Information

Insect: Pediculus humanus
Gene Symbol: -
Assembly: GCA_000006295.1
Location: NW:6248-10522[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00012 0.0079 15.9 0.1 1 23 286 308 286 308 0.95

2 12 6.2e-05 0.0042 16.8 1.3 1 23 316 338 316 338 0.98

3 12 4.9e-05 0.0033 17.1 0.4 2 23 346 367 345 367 0.96

4 12 2.6e-06 0.00017 21.1 2.0 1 23 373 395 373 395 0.99

5 12 0.00064 0.043 13.6 0.5 1 23 402 424 402 424 0.98

6 12 0.00012 0.008 15.9 0.1 1 23 430 452 430 452 0.94

7 12 7.9e-06 0.00053 19.6 0.1 1 23 458 480 458 480 0.98

8 12 1.2e-06 8.1e-05 22.2 1.3 1 23 486 509 486 509 0.98

9 12 3.6e-06 0.00024 20.7 0.5 1 23 515 538 515 538 0.96

10 12 5.6e-07 3.7e-05 23.2 1.5 1 23 544 566 544 566 0.99

11 12 5.4e-06 0.00036 20.1 0.6 1 23 572 594 572 594 0.97

12 12 0.00063 0.042 13.6 0.1 1 22 600 621 600 624 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00012	0.0079	15.9	0.1	1	23	286	308	286	308	0.95
2	12	6.2e-05	0.0042	16.8	1.3	1	23	316	338	316	338	0.98
3	12	4.9e-05	0.0033	17.1	0.4	2	23	346	367	345	367	0.96
4	12	2.6e-06	0.00017	21.1	2.0	1	23	373	395	373	395	0.99
5	12	0.00064	0.043	13.6	0.5	1	23	402	424	402	424	0.98
6	12	0.00012	0.008	15.9	0.1	1	23	430	452	430	452	0.94
7	12	7.9e-06	0.00053	19.6	0.1	1	23	458	480	458	480	0.98
8	12	1.2e-06	8.1e-05	22.2	1.3	1	23	486	509	486	509	0.98
9	12	3.6e-06	0.00024	20.7	0.5	1	23	515	538	515	538	0.96
10	12	5.6e-07	3.7e-05	23.2	1.5	1	23	544	566	544	566	0.99
11	12	5.4e-06	0.00036	20.1	0.6	1	23	572	594	572	594	0.97
12	12	0.00063	0.042	13.6	0.1	1	22	600	621	600	624	0.92

Sequence Information

Coding Sequence: ATGAGTAAAGATGTGATCATCAGTCAattggaaaacaaacaaaactgcCTAATTTGTAATGCTCAACTGGCAGTCTCAACACGAAATTGCTTTAACATATTTAAAACCATATTATTTCCTTTAGAGAAAAAAGCATGTGACTTAATTGgggCTGTATTAGATATTGAAGTAACAGAAAATTCTTTACATAGTGAtgtcatttgtaaaaaatgctTTAAACTTGTCAATGAATTTGCCGATTTAGAATCTAGAGTTAgtgaaataaaatatgaaCTGACTActaattttaagaaaacaacAGAATTTTTGCAAAGTATAGAGGAAGACAGCACTGATACATGCAAAAGCgGGATTCAAATAATCCATAAAAAAGATGGCCAAATATTACATGAAAAATCGAGGATTAAATTAGAAgatgataaattaaatcaaattgttTTAAGTAGTGCAAAGGGAAGTGCAATTATATCAAAAAATATGATAGTTCTTCCTGATCAATCTAGCAAGGATGGAACAGATTTGGATGAgcCCAAAGTTATTGTTGTAGGAAATGGAGATTTAAATGAGATTGACGTAGAAGAATATGAAATAGGAGAAGTTATTGAAGATTTCGAAGTCACAAATGCTGATCACGAAGAGATTGTAGCAGTTCAAATTCGTtctgaaaatgatgaaaatgaataTATTGTTAATCAGCAGGGTGCAGATGGGGAAATCAAGCATGTTGAAATGGACGGAAACAAATTTACGTGCTTACTATGTCCGTCTGATGGTGAAAATAAACCCTTTACTTGTGAGTCCAAAGATTTAGGATTTATGACTTTGCACCTTAAAGTTGATCATGATaCCCGAGTGTACATTTGTGATATTTGCGGACTtgaatttagaaaaagaaatgatttatCAGCGCATTTGGATGACCATGTGGCACAAGAAGAAGGAGATTTTCAATGTGAAGTATGCAATAGAATATTTAGTAACTTAAGACTTTATAGGATTCATAAAAGATTACATTCTTCGCAAAATAAATCGTGGTCTTGCGAAGTGTGTGGTAAAAAGTACagttcgAGAAACTTATTAGAGGAACACAATAATACCCATACCGGAGTTCGTCCTTATGTTTGTTCAAATTGTGGCAAAGACTTTGCATCAAAGTACACATTTAAAGCCCATAAAAAAACGCATGAAGCTAGAGAacgaaatttttcttgttcGGCTTGtgacaaaacatttttgtcCGCCCAAAATTTAATCCAGCACGAAAAAACGCATTCAGAATCCAAAGATTACGTATGTGATACCTGCGGAAAAGGTTTTGGGTCCCTTAGAAATTTGGAAGTTCACAGCGTCGTACATTCTGGATTCAAGCCTTTTATTTGCGGTGTTTGCGGAAAAGCATTTGCTAGAAAAGCCGAAATTAAAGATCACGAAAGGACTCATACGGGTGAAAGGCCTTTTCAATGTGAATTTTGCGGAGCTCAATTTAGTCAAAGAAGTAATCTTCAATCTCACAAAAGAGTCACTCATTACGACGATCGGAGgtatAGGTGCGAGGATTGTGGTAAAGGGTTCAAGCGTCGAAGATTATTAGATTATCACATAAAAGCTGTTCATACCGGAGAGAGACCATTTAAATGCCCAACTTGCGATGCCACTTTTGTTTACCCggaacattttaaaaaacatattagAATTCATACTGGAATAAAACCGTACAAATGTGAAgTCTGCGGAAAAGCTTTTAATAGTAGAGACAATAGAAATGCTCATAGATTTGTACATAGCGACAAAAAACCTTACGAGTGTTTGGTTTGCGGAATGGGATTCATGAGAAAGCCTTTACTGTATAATCACATGCAGCAAGCGgGACATATCAATGATACAATTGTTGTTAATCAACCGAGACTTACCATAGAGGATGATCAATTAATTGTACCCGATAGAGATGTAGATATTGAAATGACAATTGTCGACGATAACGGTTTGACTCAAGAAGGAGTATTGGAAGAAaagccaaaattatatttaacggAGTTAAATGAACACGTTATCATACAAGGTAACGAAAAAACATTATTCATGACTGATggtatgaaaataaaaactttaaacgaTGATGAAGACCAAGAACAATTGGTGGACGAAAGTGGAAATTTTGTCGATATGGATGGAAACATAATAGAAATAGAAGATGATAGTAATATTGCTATGACTGCTCACATTAACGAACACGGTCAACTTGTCAACGATGAAGGACAAATAATAAACGAGCACGGACAAATTTTGACTGAAGATGGACAACCCCTTGTCGTAGACGAAACcGTTAGTTTTTCAgaatgtgacgtcattgtaAAAGGTGAAAAATCGGACGAAGAAAGTAATTATTCGggtaaaaaaccggaagtgcaTTATGTACAAATAAGACTTCCAGACGACGGAAATAACGAACAGAGAACTTGGTTTAACATAGTTGAAAATAATCAAGTGGAAAATGCCAGTTAA
Protein Sequence: MSKDVIISQLENKQNCLICNAQLAVSTRNCFNIFKTILFPLEKKACDLIGAVLDIEVTENSLHSDVICKKCFKLVNEFADLESRVSEIKYELTTNFKKTTEFLQSIEEDSTDTCKSGIQIIHKKDGQILHEKSRIKLEDDKLNQIVLSSAKGSAIISKNMIVLPDQSSKDGTDLDEPKVIVVGNGDLNEIDVEEYEIGEVIEDFEVTNADHEEIVAVQIRSENDENEYIVNQQGADGEIKHVEMDGNKFTCLLCPSDGENKPFTCESKDLGFMTLHLKVDHDTRVYICDICGLEFRKRNDLSAHLDDHVAQEEGDFQCEVCNRIFSNLRLYRIHKRLHSSQNKSWSCEVCGKKYSSRNLLEEHNNTHTGVRPYVCSNCGKDFASKYTFKAHKKTHEARERNFSCSACDKTFLSAQNLIQHEKTHSESKDYVCDTCGKGFGSLRNLEVHSVVHSGFKPFICGVCGKAFARKAEIKDHERTHTGERPFQCEFCGAQFSQRSNLQSHKRVTHYDDRRYRCEDCGKGFKRRRLLDYHIKAVHTGERPFKCPTCDATFVYPEHFKKHIRIHTGIKPYKCEVCGKAFNSRDNRNAHRFVHSDKKPYECLVCGMGFMRKPLLYNHMQQAGHINDTIVVNQPRLTIEDDQLIVPDRDVDIEMTIVDDNGLTQEGVLEEKPKLYLTELNEHVIIQGNEKTLFMTDGMKIKTLNDDEDQEQLVDESGNFVDMDGNIIEIEDDSNIAMTAHINEHGQLVNDEGQIINEHGQILTEDGQPLVVDETVSFSECDVIVKGEKSDEESNYSGKKPEVHYVQIRLPDDGNNEQRTWFNIVENNQVENAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01308170; iTF_00362704; iTF_01251235;
90% Identity: iTF_01251235;
80% Identity: -