Phum000365.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pediculus humanus
Gene Symbol
-
Assembly
GCA_000006295.1
Location
NW:526117-538234[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 39 6.4 4.3e+02 1.0 0.4 1 23 124 147 124 147 0.84
2 39 0.08 5.3 7.0 2.9 1 23 152 174 152 175 0.95
3 39 0.0081 0.55 10.1 6.1 2 23 188 209 187 209 0.95
4 39 0.77 52 3.9 1.1 3 23 217 237 216 237 0.96
5 39 0.0013 0.086 12.6 1.1 2 23 248 270 243 270 0.90
6 39 6.9 4.6e+02 0.9 1.9 3 23 304 322 302 322 0.74
7 39 2.8 1.9e+02 2.2 0.3 3 23 329 349 328 349 0.88
8 39 0.6 40 4.2 3.0 3 23 356 377 355 377 0.96
9 39 0.013 0.88 9.5 0.7 1 23 383 406 383 406 0.95
10 39 1.6e-06 0.00011 21.8 0.1 1 23 412 435 412 435 0.98
11 39 0.0025 0.17 11.8 2.0 2 23 442 463 441 463 0.97
12 39 0.0012 0.081 12.7 1.6 1 23 469 491 469 491 0.99
13 39 0.015 0.97 9.3 1.4 1 23 497 520 497 520 0.94
14 39 0.0058 0.39 10.6 0.4 3 23 534 553 532 553 0.96
15 39 0.00057 0.038 13.8 1.2 3 23 561 581 559 581 0.95
16 39 0.0014 0.091 12.6 2.6 1 23 587 609 587 609 0.92
17 39 9.5e-05 0.0064 16.2 0.4 1 23 615 637 615 637 0.98
18 39 4e-05 0.0027 17.4 1.6 1 23 643 665 643 665 0.98
19 39 0.0027 0.18 11.6 0.2 1 21 672 692 672 693 0.95
20 39 0.0044 0.29 11.0 0.2 3 23 706 727 705 727 0.95
21 39 0.51 34 4.5 0.2 1 23 733 756 733 756 0.97
22 39 0.0017 0.11 12.3 0.3 2 23 775 797 774 797 0.96
23 39 0.11 7.6 6.5 3.1 1 23 804 827 804 827 0.97
24 39 0.11 7.3 6.6 3.2 2 23 840 861 839 861 0.96
25 39 0.00011 0.0077 16.0 2.1 1 23 866 888 866 888 0.99
26 39 9e-06 0.0006 19.4 0.2 1 23 894 916 894 916 0.96
27 39 7.7e-07 5.2e-05 22.8 0.1 1 23 922 944 922 944 0.98
28 39 0.0003 0.02 14.6 2.2 1 23 950 972 950 973 0.95
29 39 3.8e-05 0.0025 17.5 0.5 2 23 981 1003 981 1003 0.96
30 39 0.00019 0.012 15.3 1.0 3 23 1011 1031 1009 1031 0.93
31 39 0.0021 0.14 12.0 0.5 1 23 1037 1059 1037 1059 0.96
32 39 8.4e-05 0.0056 16.4 1.2 1 23 1065 1087 1065 1087 0.98
33 39 6.9e-05 0.0046 16.6 1.5 1 23 1093 1115 1093 1115 0.99
34 39 0.027 1.8 8.5 0.1 1 11 1121 1131 1121 1140 0.82
35 39 0.28 18 5.3 2.1 1 23 1145 1167 1145 1167 0.95
36 39 0.031 2.1 8.3 0.4 2 19 1174 1191 1173 1194 0.91
37 39 2.3e-05 0.0015 18.1 1.4 1 23 1201 1223 1201 1223 0.97
38 39 1.5e-05 0.001 18.7 2.8 2 23 1230 1251 1229 1251 0.97
39 39 4.6e-06 0.00031 20.3 1.9 1 23 1257 1279 1257 1279 0.99

Sequence Information

Coding Sequence
ATGAGGGAAACGTCAAAATCGGTCGAAGATGGGGATTCATTGATCAGAAGACTTTTGAGTAACAAAGAAATTTCGTTGAATAGGAAAAAATCGGCgggggagaaggagaaggaggaggaggaggagggtgaCTACGTCGTCACGGacgtgaaagaaaaatggtcgataataaaaaaattgatggaaGGAAATGGCGTCGGTGACAAAATTCCATCAGCGAAAGAGGAAACGTTGAAATGTTTGGAGTCGATGTTGAGAAAGCCGAAGAAGTTGAAGGATTCTCTCGTCTTTTGCAAACCCTGCAACTTATTCatgaaaaaatcaagtttGAGCGGTCACAATCGGTTCgttcataaaaaaatcaaaaaattcctTTGTCAGACTTGCGGATACGCTACGCACACGGGCACCATACTTAGACAGCACATACAAGCCGTACACGTGGGTTACACGTTCGAATGCGgtaaatgtttgaaaaaattcaacttgTTGAAAAGGTTGAGAAAACACGAGGAAATCCATCATTCGAAAGGGCCCCCCAAAGTCCCGGATAAAAAACTCATGTGTCACTGCTGCGGTTTGTCCTTTCACCGGCCGTCATATTTGAAAACTCACCTTCTCACTCACACGGAAGAGACTCCGCACGGGTGTCAGTTTTGCGAGAgaagatttaaatttcgttGGGCGAAAGTTCAACACGAGAGACTTCACACGGGTGACAAACCCTACAAGTGCACGAAAGTCTGCGACATATGCGGGTATCAAGTCGAGGGAAAGGGAACGCTCAACAAGCACATGCGAGAGAAACACGACGAGGGTCAAAACTATTGCGATCTCTGCGAGAAATACGTTTGGATCAAGTGCTACGACAAACACATAAAAGACGTGCACGAGGATCACGAGGATTTTTGCAAGACTTGTTCAAAATGGTTCAAATACTACAAGACTCACATGAGAACGTCGCACAAGGACGTGGTGAAATTTTGCGACTACTGTCAAGTGGACGTGGAAGCTCACACGTTGGAAAATCACATGGCGACCGTGCATTCGAAACAGAGTAGATTTTGCGAAACGTGCAACAAggaatttttcgaattcgtttgTTACAAAAACCACGTGAGAAACATTCACCTCAAAGTGAAATCGTACAAGTGTTCGGAATGCGATTTCACGACGGCCTACAGAACGTCCATGGACAAACACATACTCGGAACGCACACGAGAAATCAGAAATACGTGTGCGAGATATGCGCGAAAGAGTTCATAGTCAAAGACAATTTGCGCAAGCACATAAGGATGATACACAACGGACAGCAGAAATCCGTTTGCACGTATTGCGGCAAAGTCTGTCACGCGAATCGCGAGCTCATCAATCACGTTCGACTTCACACGGGCGACTTGCCCTACCAGTGCGAGTTCTGCCTGAGAAAATTCCCGAAAAAATGGACTCTGGACAATCACAGGCGAATACACACGGGTGAGAAACCCTACAAGTGCACTCATTGCGAGTCCGCGTTCGGAACGTCCGCCCAAATGAAAATCCACGAATTTCGCGAACACGGAGTCGAAAAATATCTGTTGAAACCGCAATTCATCGACTGCGAAGTCTGCGGGAAAAGCGTTCAGAGAAGAAAATTCAAGTTGCACATGATGGTGCACAACGGTGAAAAACCTCACCTCTGCGACATTTGCGGGAAAAGTTTCACGTGGAAATTTGCACTCGTCACGCACAAGAGAGTTCACTCCGGAGAGAAACCCTACCTGTGCAAGCACTGCGGTCAAAGTTTTAGATCGTCGTCTAGATTTGCCGAACATTCGACCATACACACGGGACGAAGGTCGTACGTGTGCGAAAGGTGCGCACTCGCTTTCCGGACGAGCGGACGATTGAAAAGACATTTGAGAATTCACACGGGAGAAAAACCCTACATATGTTCGTTTTGCGAAAGGGGATTTTCCGAGAGTTACAATTTGAAACAGCATCGGAGACTGCACACGGGAGAAAAACCCCCGCACGTGTGCTACGTGTGCACTCAAGCATtcataagaaagaaaatgctCGTGGATCATTTGAGAATACaaaatttatcggaAATTGTCCGAACGGTCAAACTTTGCGACGTGTGTTCGCAACCTTTTCGTAACGTTTCGTCATTATTGTCGCACAGGAAAGCGGAACATCCGGACAAGACGACATTTAAGTGTGCGGAATGCGACGACGAATCCCTGACGAGTTGGACGGTTTATGAAAAACACGTGAAAAATCACAAGCGTTCGTCTGTGTcatcgacgtcgacgtcgacgacgacgacgaaaaccgTTCGGTGCGACGTTTGCAACAAGGATTTCGAATACATAAACTCACTCGTACAACACCGGAGAGTCACGCATCCGACGGagaacaaaattttctcttgCACCCTCTGCGAATTCACCGCGACCCTATACAAGGACTACAAACACCACATGAGAGTGAGTCACAAGGATTCCGGAGTCAAACTATCTCTCTCGTGTCTCGTGTGCGACGTTTGCGGAAAAGAATTCCTCTGTCACTACAACTTGTCGAATCACATGAAATACCACGGATCGCCAAAGTTCAAGTGCGACGTGTGCGGAAAACTTTTCAAAGCGAAGAAATCCCTACAGGGTCACCACAGGATACACACGGGAGAAAAACCCTACACGTGCGAAACGTGCGGAAAAAGTTTCCCGGGTAAAAGTTATCTCATCAATCACGGCGTGACACATTCGGGTCGTAAACCGTTCGTTTGCGACGTTTGCGGAAAAGCCTTTTCGAAAAAGTGGAATCTCGTACAACACGAAAGGATACACACGGGAGAACGTCCCTACAGATGCGAACACTGTCCGAAAGTTTATCCGTCTCAAGGAGGTTTGAGCTATCACAGGTACATACATCACAGCGCTCAGTACACTCCGCCGGTGTGCGACATATGCGGGAAAACGTTCAGGGTACAGAAGTATTTGGATTCTCACAAGAACACGGTACATTTCAAGAACAAGGATCACCTCTGCGATTTGTGCGGAAAAGGTTTCGCGTCCAAGTACAGTTTGAAGCTGCACAAGATATGGCACAGAGGAGAAAAGAATTTCTTTTGCGACGTTTGCGGAATGAGATTCAGCACCGTGGGAAAAGTCAACACTCACAAGCAAGTTCACGGAGGTCCCAAGAATTACATTTGCGAAGTTTGTTCGAGAGCGTTCAGGTGGAAGAAAAGTCTGTTCACTCACATGAGGACTCACTCGGGAGAGAAACCGTTCAAGTGCGAACACTGCGAAAGGACGTTCTCGGCGCTTTGGAACATGCAGCAACACGTTAGGATACACACGGGAGAGAGGCCATACAAGTGCGACGTTTGCGGTAAAGCGTTCGCGTTGAACGCGAGACAACGTCACATAAATGACAAATCCGAATATTTTTGCGATTTctgtttgaaaatatttaaaacgaaagcCATATTGAAAGGACACAGGTACAAACACGTAACGGACCCCCAATTTTTATGCGTTAGGTgcggtaaaaaatatttcacgaTAAGTAATTTGAACGAACACAGTTTGTATTGTTtggatgagaaaaaatttcaatgtccCGTTTGTAGTAAGAAATTCAACGTCAACAAACAATTCAAACGTCATCTCGTCATACACGAAGCCGACAGGTACATAAAATGCACCGTGTGCGAACAAACGTTCAGTCGTAAGGATAATTACAGGCAACATTTCCGTAGGCACACGGGTGAGAAACCCTACACGTGCGATATATGCGGTAAATCGTTTAGGATAAAAGCGACGTATAATTACCATAGGAGAACGCACAGAGACGTCAGGACGACGACGGCGGCGGGGGCGGTGGCGGCGGGAAAGCCGATGACGACGGAAGATTCGGATAATAAAACGGCAAACGAGTACGACGGtcgaggaggagtaggaggaggaaggggggatAATTACTACGGTGATAATAACTATCGGGTACGAGATAAGGAGGATAGTACGACGAATGATGAGTATTATAATGACGTCAAAAGAGAACCCGTAGAAAGCGAAATGAGAAAaggggatgatgatgaagacggcgatgacgatgacgatgaggGTGAAACAATTTCCGGAAGAGGAAATGGAAGAAGTACCGATTATACCGACGACGCGTTAGGTACCGAGTATTaccaaagaaaagaaaatgagtacTCGTATAGGGAAATATCTCAAGTTCTACCCGATTATTTATCGAGGAGAGGAGTGGATGTCGGTCGTGGCAGTACCGGCGGGGAAGAATATCAAACCCGTGACGACACAACAAACGTACCTGAATACGCGACGAGGCGGAACGCGACGGCGTCGACGAATTATTCACAGTATTCATCCAACGTTAGAATCCGGGATAATCCGgataaggataataataatcatcacggaggattttga
Protein Sequence
MRETSKSVEDGDSLIRRLLSNKEISLNRKKSAGEKEKEEEEEGDYVVTDVKEKWSIIKKLMEGNGVGDKIPSAKEETLKCLESMLRKPKKLKDSLVFCKPCNLFMKKSSLSGHNRFVHKKIKKFLCQTCGYATHTGTILRQHIQAVHVGYTFECGKCLKKFNLLKRLRKHEEIHHSKGPPKVPDKKLMCHCCGLSFHRPSYLKTHLLTHTEETPHGCQFCERRFKFRWAKVQHERLHTGDKPYKCTKVCDICGYQVEGKGTLNKHMREKHDEGQNYCDLCEKYVWIKCYDKHIKDVHEDHEDFCKTCSKWFKYYKTHMRTSHKDVVKFCDYCQVDVEAHTLENHMATVHSKQSRFCETCNKEFFEFVCYKNHVRNIHLKVKSYKCSECDFTTAYRTSMDKHILGTHTRNQKYVCEICAKEFIVKDNLRKHIRMIHNGQQKSVCTYCGKVCHANRELINHVRLHTGDLPYQCEFCLRKFPKKWTLDNHRRIHTGEKPYKCTHCESAFGTSAQMKIHEFREHGVEKYLLKPQFIDCEVCGKSVQRRKFKLHMMVHNGEKPHLCDICGKSFTWKFALVTHKRVHSGEKPYLCKHCGQSFRSSSRFAEHSTIHTGRRSYVCERCALAFRTSGRLKRHLRIHTGEKPYICSFCERGFSESYNLKQHRRLHTGEKPPHVCYVCTQAFIRKKMLVDHLRIQNLSEIVRTVKLCDVCSQPFRNVSSLLSHRKAEHPDKTTFKCAECDDESLTSWTVYEKHVKNHKRSSVSSTSTSTTTTKTVRCDVCNKDFEYINSLVQHRRVTHPTENKIFSCTLCEFTATLYKDYKHHMRVSHKDSGVKLSLSCLVCDVCGKEFLCHYNLSNHMKYHGSPKFKCDVCGKLFKAKKSLQGHHRIHTGEKPYTCETCGKSFPGKSYLINHGVTHSGRKPFVCDVCGKAFSKKWNLVQHERIHTGERPYRCEHCPKVYPSQGGLSYHRYIHHSAQYTPPVCDICGKTFRVQKYLDSHKNTVHFKNKDHLCDLCGKGFASKYSLKLHKIWHRGEKNFFCDVCGMRFSTVGKVNTHKQVHGGPKNYICEVCSRAFRWKKSLFTHMRTHSGEKPFKCEHCERTFSALWNMQQHVRIHTGERPYKCDVCGKAFALNARQRHINDKSEYFCDFCLKIFKTKAILKGHRYKHVTDPQFLCVRCGKKYFTISNLNEHSLYCLDEKKFQCPVCSKKFNVNKQFKRHLVIHEADRYIKCTVCEQTFSRKDNYRQHFRRHTGEKPYTCDICGKSFRIKATYNYHRRTHRDVRTTTAAGAVAAGKPMTTEDSDNKTANEYDGRGGVGGGRGDNYYGDNNYRVRDKEDSTTNDEYYNDVKREPVESEMRKGDDDEDGDDDDDEGETISGRGNGRSTDYTDDALGTEYYQRKENEYSYREISQVLPDYLSRRGVDVGRGSTGGEEYQTRDDTTNVPEYATRRNATASTNYSQYSSNVRIRDNPDKDNNNHHGGF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-