Basic Information

Insect: Pediculus humanus
Gene Symbol: ZNF236
Assembly: GCA_000006295.1
Location: NW:275437-280760[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 0.0017 0.11 12.3 1.4 1 23 262 284 262 284 0.96

2 27 0.019 1.2 9.0 1.2 1 23 291 313 291 313 0.97

3 27 7.5e-05 0.005 16.5 0.3 2 20 319 337 318 340 0.92

4 27 0.075 5 7.1 0.6 3 23 348 368 347 368 0.96

5 27 0.41 27 4.8 3.4 2 23 388 409 387 409 0.89

6 27 7.8e-07 5.2e-05 22.8 0.3 2 23 439 460 439 460 0.97

7 27 9.6e-06 0.00065 19.3 0.9 1 23 466 488 466 488 0.98

8 27 0.012 0.81 9.6 3.0 1 23 494 517 494 517 0.94

9 27 1 67 3.5 5.9 1 23 527 550 527 550 0.92

10 27 2.1e-07 1.4e-05 24.5 1.4 1 23 669 691 669 691 0.98

11 27 4.2e-05 0.0028 17.3 3.6 1 23 697 719 697 719 0.99

12 27 2.1e-06 0.00014 21.4 1.3 1 23 725 747 725 747 0.99

13 27 0.0041 0.27 11.1 3.5 1 19 753 771 753 777 0.94

14 27 0.00019 0.012 15.3 5.0 1 23 832 854 832 854 0.97

15 27 0.0001 0.0068 16.1 2.5 1 23 860 882 860 882 0.98

16 27 0.00013 0.009 15.7 2.1 3 23 890 911 888 911 0.97

17 27 7.5e-05 0.005 16.5 4.6 1 23 917 939 917 939 0.98

18 27 6.4e-06 0.00043 19.9 1.5 1 23 1130 1152 1130 1152 0.98

19 27 0.0027 0.18 11.6 0.4 1 23 1158 1180 1158 1180 0.96

20 27 0.00072 0.048 13.4 2.5 1 23 1186 1208 1186 1208 0.98

21 27 1.3e-07 8.9e-06 25.2 0.9 3 23 1285 1305 1284 1305 0.98

22 27 4.9e-06 0.00033 20.3 5.8 1 23 1311 1333 1311 1333 0.99

23 27 0.00016 0.011 15.5 1.0 2 23 1340 1361 1339 1361 0.97

24 27 4.5e-05 0.003 17.2 2.5 1 23 1367 1389 1367 1389 0.98

25 27 2.2e-07 1.5e-05 24.5 1.8 3 23 1550 1570 1549 1570 0.98

26 27 1.4e-06 9.2e-05 22.0 0.8 1 23 1576 1598 1576 1598 0.97

27 27 1.1e-05 0.00072 19.2 2.2 1 23 1604 1627 1604 1627 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	0.0017	0.11	12.3	1.4	1	23	262	284	262	284	0.96
2	27	0.019	1.2	9.0	1.2	1	23	291	313	291	313	0.97
3	27	7.5e-05	0.005	16.5	0.3	2	20	319	337	318	340	0.92
4	27	0.075	5	7.1	0.6	3	23	348	368	347	368	0.96
5	27	0.41	27	4.8	3.4	2	23	388	409	387	409	0.89
6	27	7.8e-07	5.2e-05	22.8	0.3	2	23	439	460	439	460	0.97
7	27	9.6e-06	0.00065	19.3	0.9	1	23	466	488	466	488	0.98
8	27	0.012	0.81	9.6	3.0	1	23	494	517	494	517	0.94
9	27	1	67	3.5	5.9	1	23	527	550	527	550	0.92
10	27	2.1e-07	1.4e-05	24.5	1.4	1	23	669	691	669	691	0.98
11	27	4.2e-05	0.0028	17.3	3.6	1	23	697	719	697	719	0.99
12	27	2.1e-06	0.00014	21.4	1.3	1	23	725	747	725	747	0.99
13	27	0.0041	0.27	11.1	3.5	1	19	753	771	753	777	0.94
14	27	0.00019	0.012	15.3	5.0	1	23	832	854	832	854	0.97
15	27	0.0001	0.0068	16.1	2.5	1	23	860	882	860	882	0.98
16	27	0.00013	0.009	15.7	2.1	3	23	890	911	888	911	0.97
17	27	7.5e-05	0.005	16.5	4.6	1	23	917	939	917	939	0.98
18	27	6.4e-06	0.00043	19.9	1.5	1	23	1130	1152	1130	1152	0.98
19	27	0.0027	0.18	11.6	0.4	1	23	1158	1180	1158	1180	0.96
20	27	0.00072	0.048	13.4	2.5	1	23	1186	1208	1186	1208	0.98
21	27	1.3e-07	8.9e-06	25.2	0.9	3	23	1285	1305	1284	1305	0.98
22	27	4.9e-06	0.00033	20.3	5.8	1	23	1311	1333	1311	1333	0.99
23	27	0.00016	0.011	15.5	1.0	2	23	1340	1361	1339	1361	0.97
24	27	4.5e-05	0.003	17.2	2.5	1	23	1367	1389	1367	1389	0.98
25	27	2.2e-07	1.5e-05	24.5	1.8	3	23	1550	1570	1549	1570	0.98
26	27	1.4e-06	9.2e-05	22.0	0.8	1	23	1576	1598	1576	1598	0.97
27	27	1.1e-05	0.00072	19.2	2.2	1	23	1604	1627	1604	1627	0.97

Sequence Information

Coding Sequence: atggaTGATATCACTACAGAATTAAAAACTCAATCAATGTGTCAGGAAATAGCTCCTTTTGTCATAGAATTGGAAGGAAGAGGAGCTGTTTGCGTCAAGGGTGATTCTCTATATGAATTAACCAAATATGATGGCAGCAAAGTTCAAGTCACAAGTTTAGTATCACAAGAaggaatttcattttttccagtCTCTTCAGATTTAACTCAAAACGATAGTATTTATGTAGAACAAcctctttttataaatgtgCCTATTGAAAATACTCAAAATGAATTTGTATTAGATGAAGAAACTGTTGCAGTTCCTCTTGAGAATTTagagactaaaaaaaattatcaagaaattagtaattttcaaatttctgATAGCATAACTACAGAAATGGGTCAGTTTACAGAATTTGACAACAAAGTATCAATTTTAGAATTGGTTGATAATCCTGAATTGAAGGATAAACCATTAGCACAAtctgttataaaaaaaaatccaacttGCGATATTGTCTGTGAAGTTACTTCAAATGACTATTTGCCAGCTTTTGTCATTGAtgcaaatgataatttaagtagtattaaaaatgatgatagtgatgtaactattcaaaatattaatgatactGAAAATTGTGTGGCAGAAAATATTGAAGAACCTTCAATGAATTCTGCTGCAGAAAtagtttcaaatttaaaatcatcagTCGTAGATGAAGCACCGACAACCATTAAAAGGGGAAGacccaaaaaagaaaaagaaattgagcCACCATTAAGAAAAGGTCCTTTTGTGTGTGAAGTTTGTCATTTTAAAGTGGACACATGGTCACAGTTAAAGTCTCATAAATTGCTGCATTCCAAAGAAAATAAACCATTTGTTTGCAAAGTGTGTTGTGTAAGTtttaatgttgaaaaaaatctaaatctCCATATGTTGTTGCACAATGTAGGAAATTTAACTTGTCCTGAATGTAATAAAGTATTTACTAGATTTGCATCATTTAAAGCTCACTTACCCATTCacgaagaagaggaaaatgttttttgctCTGAATGTGGTGATGAATTTACAAGCATTCTTCATTTAGAGCAACACCTTCAGGATCACAGAAACGAATGGGAAAAAACAATATCTGGTGATGATGTAGAGCCAAAGAATGCTTTGACTTGTAAGACATGCAATAGAATTTTTACAAACCCAATTACTTTCGAGTGTCATAAAAAAGATCatcaaaaacttaaaaatcaattacttGCTCTGGCacctaaaagaaaaaggaaaagattttgGAATTCGAATGGGGGTAACTACACCAATGAATGCTCtgtgtgtaaaaaaagttttccaaagCCAAGTCAACTTGTTCGCCATATAAGAATACACACTGGagaaaaaccatttaaatGTACTACTTGCTCTGCTGCTTTTAGTCAAAAAGGTTCTCTTCAAATTCACATGTCCAAGCATAACGGATACAAACCTCATGTCTGTTCTTGTtgttcattatcattttcacagCGTGGAAACTTAATAACTCACGTTAATAAAGTTCATAGAATTCCGAAGGAAGGagaagaaatttataaatgcgTCAAGTGTCCGTgttcatttaaaaagttaGCTAGTTTAAATTGTCACGTTACTAGATTTCACGTTGGAGTAGAAAACAATAGTAAACCAAATTCTGAAGCCACTGGTTCCGAGGTAGATGCATTGTTAAATCAAATTGCAGAATTACGGAATAGTTTGCCATCTACTTCCGATATGGATATATTACAAACAGCTATCAGAATAAGCGGATTGCCAGTCTCGATGAAATCAACCGAAGAGGGAACTGATCGTCTTAGTAAAGATAATTTAGTCATTGATAATTTGTTTACGGAAAATTCTACTCAAAATGCAGACGCAGGATCCGAAATCCGAGTAGTGACAATAGCCGACAAAAGCGACGATGGAAATATAAAGCATTTTACGGTTCGTCAAAGAAGAGAAGGAAATATACGATGGCATCAGTGCAACGTGTgtcaaaaagaatttaaaaagccTTCGGATTTGATAAGGCACATTAGAATTCACACGAGAGAGAAACCTTTCAAGTGCAATCAGTGTTTTAGAACGTTTTCGATAAAATCAACTTTAAAATCTCACGCAAGAACTCACCAAAGTTTCAAACTTTACGAGTGTAAAATGTGCGGGAAAAAGGTGTCATCCTCTAGAAGCCTTAAAATTCATCAAAGATCTCACGTAGGAATCAGACCTTTCACCTGCAACGTGTGCATGAAATCTTTTACCACGTCGGGACAGCTAAAAAATCATTGCACGACTAATTCTCACAAAACGAAAGTCGATAACCCGGCCGGAGATTTAGAAAccgttaataacaattattttttcgaagaGCCTTTTCTCATAGTTGGCGGAGAATTCAGACAACAGCtatcgagaaaagaaaaattaattactcgtAGTCAAAATGCCAGCAGCACGGAACGTCCGTACGAATGTGAATATTGTCAGCTTAAATTTCGTAAATCGAGTCATTTAAAACAGCACAAGTTACAACATACCGGTGAAAAACCCTTTTCCTGCGTGGTCTGTCACAAAAACTTTACGACGAACGGCGTGTTAAAAATGCATTTGAAGACTCATTTAGGACAAAAAGATTTCGGATGTGATAAATGTACTAGTAAATTTTCTACGAAGGGTAGTTTAAAGAGACACATACAAACGTTTCACAGCGAAGATCGTCCATACATGTGCCCTTACTGccaaaaacgatttaaaacatCTGTGAATTGTAGGAAACACATAAAAATACACAGGTACGATAATAATCAACAGTTTATACGATTGAAACCGAATGAAATTTATTCCGAAACGGATAAAGTTATTACGGAACAAAACGAAGTCGCCAACAGCAGCAGCGCAGATGAGGAAAAAATACCAAAATCAAAAACACCCGATAACATCAGTCACACCCTGTTGGCAGACTCTACAGGAACCATAACGTTATCCGCTCTAAATCAAGAATCTCTGACTCAAGAGAGCATAAGAGAATTGGAACAAACTTTAAATCAGCAACTCTTTGGAACGGAACAAGGGCCCGAGTACAGTGTTCAAATGATATCGACCGGAGAAAATGACaaggaaaatgattttatagaGCCGTCGTTATTAACGAAGCCTTTGATTTTAAGCGTGGATGAAACCATACGAGAACCGTCGATAGTACACGCCGTGTTTTCACAAACGGAAGAGCTGCAAACTGTTTCGAATATGTCCGAAATACTGCCCGACACGAAAGACCCCGAACCGGATTACGCTgacattaatgataataacgataaagaaaatgaggaaaaCGCTTTTTgtcagaaagaaaataaaagttacGCTTGCAACACGTGCGATAAAGTATTTTCATCTCTTCAAACTCTGAAAACTCACACGAAAATGCATATggggaaaaaagaattcaattGCGAACTCTGCGGCTGGAGCACGTTGACGAGGTCATCTCTCAGACGACACGCAAGTATGCACAACGTgggtaaaaaatattcatgttCGGAATGTTCGGCGAAATTCCGCTTggaaattcatttgaaaaagcATCAAAAAGTGCACGAAGTCAGCGGGACCGATGGTAATAATCGCATCAACAGGAGAAGCAAAGGTCCCTTCAGGGAATTCAGTGATGCCGAAACGGAACTCCTGGCGGCGCAAGACATCAGACACGGAGCCAGCGTTTCGGAGAAAGTTTTAATAGAATCCGCTGCCGAAAAGCTTAGAatagaagataaaaaaaaggaagaattgCCGGGAAAAGAAAGTCGTTCGAACTTTGGAAACGATTGCAAATATTGTCagaaaagtttcaaaaaaccCTCGGATTTGATTCGACACATACGAGTGCACACGGGCGAACGTCCCTTTCAATGCACGCAATGTAATAAATGCTTCCGAGTTAAATCAACCCTTTCGTCTCATCTTCGAACGCACTACGGAGTCAAACCCGTTTCTTGCCACATTTGCCAATCAATGTTTGCTGCGAAAAGTTCGCTCAAAGTTCACATGAGACTTCACACGGGAGCGAAACCGTTCGAATGTCCGATTTGCAATCAAAGATTCCGGACTTCGGGTCACAGAAAAAACCATTTGCTATCCCATGCTAAAAACAAACctaaaacgtggaaaaagcaACAATTGCAAATGTTGAATAAAATAGCCGTGGCTTTGGTCGTGAATTTGTCAGAAGagggagaaataaataaaaatggagaatTGAAACCTGGAGAACAAAACGTTTTACAACAGGCTTTTGATTCCAGCGTGATCGACACGATTGAAAACGAATCGGAAAACGATGGCCTTTTACTGCAATTGAACGATCAAAACAATATCGTCCAGTTACTTTCCACAGAACAAAATGAGCGAGACGTTGTTACGACGGCGGAAGAAGACAACCCGCAGCAACAACCGATGCAATTTCAAATCTACACATCGGACGGTCAAGTCTACATAACCCATCCCAACTCGGATTTGATAATATGTTCGGACGAAAGCGTCGAAagcaacaacgaaaaaaatggagtcgtGACGAATAACGTGTCGGAAGATGGAGGAATGATGACAAAAATGGGAAACGCGTGTAAATATTGcaacaaaacattttcaaagaAAAGCCTTTTGGAAAGACATTTGAGAGTTCACACGGGAGAGAGACCATATTCTTGCGATTTGTGCGGTAAAAGATTCACTCAGAGCAACGCGTTAAAAACTCATTTGAAAGCTCATAAAGGCGATCGAGCTTTTTCTTGTCCCTATTGTGATTTTTCATGTGTTCAAAAAGGAAATCTTCGCATTCACATGAGCAGGACTCATCAGTTTGCATATTTCAtgggcgacgacgacgacgacgataataagaaaacaaacggaaaattgaaaacaaacaaaaataatataaatttatattccgACACCTTATTGAAAATCCCATATAAATCTCCGACGACGGTGAGAACGACGGATATTGAACAAATGGTCGGAGAATTATTTCCTCTCGTGACGtag
Protein Sequence: MDDITTELKTQSMCQEIAPFVIELEGRGAVCVKGDSLYELTKYDGSKVQVTSLVSQEGISFFPVSSDLTQNDSIYVEQPLFINVPIENTQNEFVLDEETVAVPLENLETKKNYQEISNFQISDSITTEMGQFTEFDNKVSILELVDNPELKDKPLAQSVIKKNPTCDIVCEVTSNDYLPAFVIDANDNLSSIKNDDSDVTIQNINDTENCVAENIEEPSMNSAAEIVSNLKSSVVDEAPTTIKRGRPKKEKEIEPPLRKGPFVCEVCHFKVDTWSQLKSHKLLHSKENKPFVCKVCCVSFNVEKNLNLHMLLHNVGNLTCPECNKVFTRFASFKAHLPIHEEEENVFCSECGDEFTSILHLEQHLQDHRNEWEKTISGDDVEPKNALTCKTCNRIFTNPITFECHKKDHQKLKNQLLALAPKRKRKRFWNSNGGNYTNECSVCKKSFPKPSQLVRHIRIHTGEKPFKCTTCSAAFSQKGSLQIHMSKHNGYKPHVCSCCSLSFSQRGNLITHVNKVHRIPKEGEEIYKCVKCPCSFKKLASLNCHVTRFHVGVENNSKPNSEATGSEVDALLNQIAELRNSLPSTSDMDILQTAIRISGLPVSMKSTEEGTDRLSKDNLVIDNLFTENSTQNADAGSEIRVVTIADKSDDGNIKHFTVRQRREGNIRWHQCNVCQKEFKKPSDLIRHIRIHTREKPFKCNQCFRTFSIKSTLKSHARTHQSFKLYECKMCGKKVSSSRSLKIHQRSHVGIRPFTCNVCMKSFTTSGQLKNHCTTNSHKTKVDNPAGDLETVNNNYFFEEPFLIVGGEFRQQLSRKEKLITRSQNASSTERPYECEYCQLKFRKSSHLKQHKLQHTGEKPFSCVVCHKNFTTNGVLKMHLKTHLGQKDFGCDKCTSKFSTKGSLKRHIQTFHSEDRPYMCPYCQKRFKTSVNCRKHIKIHRYDNNQQFIRLKPNEIYSETDKVITEQNEVANSSSADEEKIPKSKTPDNISHTLLADSTGTITLSALNQESLTQESIRELEQTLNQQLFGTEQGPEYSVQMISTGENDKENDFIEPSLLTKPLILSVDETIREPSIVHAVFSQTEELQTVSNMSEILPDTKDPEPDYADINDNNDKENEENAFCQKENKSYACNTCDKVFSSLQTLKTHTKMHMGKKEFNCELCGWSTLTRSSLRRHASMHNVGKKYSCSECSAKFRLEIHLKKHQKVHEVSGTDGNNRINRRSKGPFREFSDAETELLAAQDIRHGASVSEKVLIESAAEKLRIEDKKKEELPGKESRSNFGNDCKYCQKSFKKPSDLIRHIRVHTGERPFQCTQCNKCFRVKSTLSSHLRTHYGVKPVSCHICQSMFAAKSSLKVHMRLHTGAKPFECPICNQRFRTSGHRKNHLLSHAKNKPKTWKKQQLQMLNKIAVALVVNLSEEGEINKNGELKPGEQNVLQQAFDSSVIDTIENESENDGLLLQLNDQNNIVQLLSTEQNERDVVTTAEEDNPQQQPMQFQIYTSDGQVYITHPNSDLIICSDESVESNNEKNGVVTNNVSEDGGMMTKMGNACKYCNKTFSKKSLLERHLRVHTGERPYSCDLCGKRFTQSNALKTHLKAHKGDRAFSCPYCDFSCVQKGNLRIHMSRTHQFAYFMGDDDDDDNKKTNGKLKTNKNNINLYSDTLLKIPYKSPTTVRTTDIEQMVGELFPLVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -