Basic Information

Insect: Pediculus humanus
Gene Symbol: zfh1
Assembly: GCA_000006295.1
Location: NW:934311-939711[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 32 0.00097 0.065 13.0 2.1 1 23 106 128 106 128 0.97

2 32 1.8e-05 0.0012 18.5 2.1 1 23 134 157 134 157 0.97

3 32 0.00011 0.0074 16.0 2.2 1 23 163 185 163 185 0.97

4 32 0.53 35 4.4 0.3 3 23 193 213 191 213 0.83

5 32 8.7e-06 0.00058 19.5 0.5 2 23 244 265 243 265 0.96

6 32 6e-05 0.004 16.8 4.5 3 21 273 291 271 293 0.95

7 32 0.0021 0.14 12.0 0.6 1 23 299 322 299 322 0.95

8 32 5.6e-07 3.8e-05 23.2 0.3 1 23 328 350 328 350 0.98

9 32 0.0007 0.047 13.5 11.4 1 23 356 378 356 379 0.96

10 32 0.00046 0.031 14.1 3.5 3 23 388 409 387 409 0.95

11 32 0.0042 0.28 11.0 4.1 1 23 415 437 415 437 0.98

12 32 2.6e-05 0.0017 18.0 1.8 2 23 444 465 444 465 0.97

13 32 0.00024 0.016 15.0 2.5 3 23 472 492 470 492 0.95

14 32 3.1e-06 0.00021 20.9 1.2 2 23 499 520 498 520 0.96

15 32 3e-05 0.002 17.8 1.4 1 23 525 548 525 548 0.97

16 32 2.6e-06 0.00018 21.1 0.9 2 23 557 578 556 578 0.97

17 32 2.1e-05 0.0014 18.3 0.1 1 23 584 606 584 606 0.97

18 32 2.6 1.7e+02 2.2 6.0 1 23 612 634 612 634 0.92

19 32 4.7e-06 0.00032 20.3 2.3 3 23 642 662 640 662 0.97

20 32 0.00037 0.025 14.4 2.6 1 23 668 690 668 690 0.98

21 32 2.7e-07 1.8e-05 24.2 2.3 1 23 695 717 695 717 0.99

22 32 0.081 5.4 7.0 0.3 1 15 730 744 730 751 0.83

23 32 0.032 2.2 8.2 0.3 1 14 760 773 760 780 0.83

24 32 2.7e-05 0.0018 17.9 4.5 2 23 787 809 786 809 0.96

25 32 3.5e-06 0.00024 20.7 2.5 2 23 815 836 814 836 0.96

26 32 0.00018 0.012 15.4 1.0 1 23 842 864 842 864 0.98

27 32 0.52 34 4.5 2.3 1 12 870 881 870 884 0.90

28 32 2.1e-05 0.0014 18.3 0.7 2 23 900 922 900 922 0.97

29 32 4.1e-05 0.0027 17.4 4.4 1 23 928 950 928 951 0.96

30 32 1.9e-06 0.00012 21.6 0.4 1 23 958 980 958 980 0.99

31 32 6.8e-05 0.0046 16.7 2.1 1 23 986 1009 986 1009 0.98

32 32 4.9e-05 0.0033 17.1 6.5 1 23 1015 1037 1015 1037 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	32	0.00097	0.065	13.0	2.1	1	23	106	128	106	128	0.97
2	32	1.8e-05	0.0012	18.5	2.1	1	23	134	157	134	157	0.97
3	32	0.00011	0.0074	16.0	2.2	1	23	163	185	163	185	0.97
4	32	0.53	35	4.4	0.3	3	23	193	213	191	213	0.83
5	32	8.7e-06	0.00058	19.5	0.5	2	23	244	265	243	265	0.96
6	32	6e-05	0.004	16.8	4.5	3	21	273	291	271	293	0.95
7	32	0.0021	0.14	12.0	0.6	1	23	299	322	299	322	0.95
8	32	5.6e-07	3.8e-05	23.2	0.3	1	23	328	350	328	350	0.98
9	32	0.0007	0.047	13.5	11.4	1	23	356	378	356	379	0.96
10	32	0.00046	0.031	14.1	3.5	3	23	388	409	387	409	0.95
11	32	0.0042	0.28	11.0	4.1	1	23	415	437	415	437	0.98
12	32	2.6e-05	0.0017	18.0	1.8	2	23	444	465	444	465	0.97
13	32	0.00024	0.016	15.0	2.5	3	23	472	492	470	492	0.95
14	32	3.1e-06	0.00021	20.9	1.2	2	23	499	520	498	520	0.96
15	32	3e-05	0.002	17.8	1.4	1	23	525	548	525	548	0.97
16	32	2.6e-06	0.00018	21.1	0.9	2	23	557	578	556	578	0.97
17	32	2.1e-05	0.0014	18.3	0.1	1	23	584	606	584	606	0.97
18	32	2.6	1.7e+02	2.2	6.0	1	23	612	634	612	634	0.92
19	32	4.7e-06	0.00032	20.3	2.3	3	23	642	662	640	662	0.97
20	32	0.00037	0.025	14.4	2.6	1	23	668	690	668	690	0.98
21	32	2.7e-07	1.8e-05	24.2	2.3	1	23	695	717	695	717	0.99
22	32	0.081	5.4	7.0	0.3	1	15	730	744	730	751	0.83
23	32	0.032	2.2	8.2	0.3	1	14	760	773	760	780	0.83
24	32	2.7e-05	0.0018	17.9	4.5	2	23	787	809	786	809	0.96
25	32	3.5e-06	0.00024	20.7	2.5	2	23	815	836	814	836	0.96
26	32	0.00018	0.012	15.4	1.0	1	23	842	864	842	864	0.98
27	32	0.52	34	4.5	2.3	1	12	870	881	870	884	0.90
28	32	2.1e-05	0.0014	18.3	0.7	2	23	900	922	900	922	0.97
29	32	4.1e-05	0.0027	17.4	4.4	1	23	928	950	928	951	0.96
30	32	1.9e-06	0.00012	21.6	0.4	1	23	958	980	958	980	0.99
31	32	6.8e-05	0.0046	16.7	2.1	1	23	986	1009	986	1009	0.98
32	32	4.9e-05	0.0033	17.1	6.5	1	23	1015	1037	1015	1037	0.98

Sequence Information

Coding Sequence: atgaaATGTCTGCAACAAGATAAAACTAGTTTTGTTTTCAGATTTGAGAATGAATCagatttatcattttcaactTATCAGTATCAATTCAATATACATGTACCTTTTATTAACaagatattaaatttaaatatctgTGAGAGTTTCTGTTGTGAGAATTGtacaattattgaaaatttaaaactttttttaactaaacttaaagttaattttttcaaagacAAAGAAGCCGACGAGTTAATAAAGGATGGGAATGAATCATTAGTAGGAGAgatcaaatcaaaaatttcaaaaaatttaaaatccccaaaaaaattcatttgtaaaaaatgtcAGGAAGTTTTTCACACAAGACtcggtttaaaaaatcacgtgaaaaTTCATtgcgatataaaaaaattttcttgcgaGATTTGCAATAAGAATTTCGGACATCGTTTCAATTTATCTCGACACGTAAAAGTCATACACGAAGGTGTTAGAAATCACGTTTGTTCGGATTGTGGTAAAAGATACAGGTCACACGGTGAGATGGAAGATCATAGAAACATTCACAAAGTTCAAAATAAGATCATTTGCGAAGAATGCGGACGGATTTTTCTCACCAAAGCATCATTTTACCCCCACAGAAAATTTCATCGAATGTCTAAAACTAAAACGGTTCACGGAAATAAATACGGTTGcgacgaatATCAGCACATGCTGATACATACGGGAGAAAAACCGATCGTGTGTGCCGTctgtgggaaaaattttagaacGAAAGCTAATTTTAGACAACATTCAAAAGTTCATACGAAAATCAGACCGTTCGGTTGCGATCACTGTGGGAAAGCGTTCGCCAGAAAAGATCATTTGAAAATTCACGTTCGATGTCATACGGGAGAAAAACCGTTCGTTTGTGATTTCTGCGGAAGAGTTTTAGAATCTTTACGTTGTTTGCAACGTCACGTGACAGTCATACACGAAGGAATACGACGATATAAGTGTCCCATTTGTTCGAAAGTGTTCGATTCAAACGGGGAATTGAAATCTCATCAAGATTCTCATTCCGATCCGAGGCCTTTTCAATGCGATCAATGCGGTCGAACTTTCATTCATCAAAAACATTTGTACCATCACAGAAAGTATCATCACACAGCGAACGGAATGAGACGTCTTTGCAAAGTTTGCAATCGTCATTTTTCAAGTCCGAGCGTTTTGAAAAGGCATCACAAAGCGATTCATTTGGGTTTGAAAGAATTTCAGTGTCACGTATGCAGCGCGCAACTGAGCACAAAACATTATTTGCAAGAACATTTGAAATTGCACTCGGACGAAAGATCGGAAGTGTGCAAATTTTGCGGTAAAACATTTCAAATGACCGGAAATTTAAGGCAACATTTGAAAACGCACATGAGGAAAAGTCAAATTTGTTACGTGTGCGGTAAGGGATTCACGAGGAAATGTCATTTGCTCATACATTTGGGATCTCATAAAGAAATCGAACACCTTGAATGCGAATATTGTCAAAAAGttttcaatcgAAGGTTTAATTTCGAAAGACATTTGTCCGTTCATTCCGGAGATTCGTACACGTGTCACGCTTGCGGAAAACAATACAAAAGACAATCCGTACTCGACAgacacataaaaataattcaccaacaaataaaatttgctAATTTATCTTGTAGTTATTGCGGTAAAGTATTTTCTTCGACTCAAAGTCTCGAAGATCATTTTAGGACTCATACGGGAGAAAGGCCGTTCATATGCGAAATATGCGGAAAAGATTTCAGGGCTAGACCCAATCTCATTgctcataaaaaaattcacacgggAGAATTACCCTTCGCCTGTTCTCTTTGCGATTATCGATGTCGTCTCAAAAGTACTTTTATAGATCATTGTCAACGTCACGAAGGTACGCGATCGTGCCTGTGTTCGATATGCGGAAAAGGATTCGTTAACAATTACGATTTGATGAAACATAAGAAAACTCATTCGAAAGAAAGGCGATTCTCTTGTTCGTTTTGCAGTTTGACGTTCGTCATGAAAAGATATTTAAAAGTTCATTTGAAAACTCATTCACAAAAAATGTTTAAATGTAACGATTGCGGAAAAGCATTTaaggaaaaatcgaaattatcgaatcatttaaaaaaacatggaagGGAATCGTCGGACGtggataaattgaaaaaattttcatgcagCGTTtgcaatagaaaatttaaattcgaggACAACGGATTGGCCCACGAGAAAATATGCGGTAAAAAAGAAGGAATGACTCACAAGTGTTCGGTTTGCAACAAAcgtttcgaatcgaaaatcCTTGCCGATCAACATTGGACGTGTCATCACAAATCCTGCGTGTGTCATTTTTGCGGTCAATCATTTTCCAAATCCGAATCTCTCAAGCAACACGTCAAAACCGTACACGAAGAATTCAAATTGGTTTGTCATTACtgcggtaaaaaattttctaggaAAGCGAGATTGCAAGAACACCTACAATATCACACCGGGCAAATGGAATTCACGTGTCACGTTTGCGGAAAAGGTTCGACGAATTCGTATTCGTTCGGCATACACCTGGCGACTCACTCTCAAGAAACACCTTACTCGTGTTCGTTTTGTCCGCGAACGTTCAAACACATGAAATACAGTTATGCGAAGCCGAAAAAACCGGGGAAAAACGTCGTCGAACGAACGTGTTCCCTCTgcgataaaacatttaaaagagTAAGTGCACTTTTGATACACAAGCGATCCGTACACGAGGGTAAAAACGGGTACGTGTGTAAATTATGCGGTAAAGATTTCAAATACTCTTATCTGTTGTTCGTCCATAAGAAAAAACATCATTTTCCGGAACTGTGTAAATACTCGTGCGAAATATGCGAGAAaccgtttccggttaaaacggaattgaaaaatcatttgCGTAAACACACGGGAGAAAAACCCTACGTTTGCGGTCTGTGTGGTAAATCGTATTCGTTTCACGGGTCGTTGAACATGCACAAAAAAACTCAAcacgaaaataagaaaatattcaaATGCACCATTTGCGAATGTTCTTATAATTTCAAATCCCATTTAACGAGACACATGAGCGTGCACGTGGAAAAATACGCGACTTTAGATTTAAACCTGAACGAAAACTTAAcgtcgtga
Protein Sequence: MKCLQQDKTSFVFRFENESDLSFSTYQYQFNIHVPFINKILNLNICESFCCENCTIIENLKLFLTKLKVNFFKDKEADELIKDGNESLVGEIKSKISKNLKSPKKFICKKCQEVFHTRLGLKNHVKIHCDIKKFSCEICNKNFGHRFNLSRHVKVIHEGVRNHVCSDCGKRYRSHGEMEDHRNIHKVQNKIICEECGRIFLTKASFYPHRKFHRMSKTKTVHGNKYGCDEYQHMLIHTGEKPIVCAVCGKNFRTKANFRQHSKVHTKIRPFGCDHCGKAFARKDHLKIHVRCHTGEKPFVCDFCGRVLESLRCLQRHVTVIHEGIRRYKCPICSKVFDSNGELKSHQDSHSDPRPFQCDQCGRTFIHQKHLYHHRKYHHTANGMRRLCKVCNRHFSSPSVLKRHHKAIHLGLKEFQCHVCSAQLSTKHYLQEHLKLHSDERSEVCKFCGKTFQMTGNLRQHLKTHMRKSQICYVCGKGFTRKCHLLIHLGSHKEIEHLECEYCQKVFNRRFNFERHLSVHSGDSYTCHACGKQYKRQSVLDRHIKIIHQQIKFANLSCSYCGKVFSSTQSLEDHFRTHTGERPFICEICGKDFRARPNLIAHKKIHTGELPFACSLCDYRCRLKSTFIDHCQRHEGTRSCLCSICGKGFVNNYDLMKHKKTHSKERRFSCSFCSLTFVMKRYLKVHLKTHSQKMFKCNDCGKAFKEKSKLSNHLKKHGRESSDVDKLKKFSCSVCNRKFKFEDNGLAHEKICGKKEGMTHKCSVCNKRFESKILADQHWTCHHKSCVCHFCGQSFSKSESLKQHVKTVHEEFKLVCHYCGKKFSRKARLQEHLQYHTGQMEFTCHVCGKGSTNSYSFGIHLATHSQETPYSCSFCPRTFKHMKYSYAKPKKPGKNVVERTCSLCDKTFKRVSALLIHKRSVHEGKNGYVCKLCGKDFKYSYLLFVHKKKHHFPELCKYSCEICEKPFPVKTELKNHLRKHTGEKPYVCGLCGKSYSFHGSLNMHKKTQHENKKIFKCTICECSYNFKSHLTRHMSVHVEKYATLDLNLNENLTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -