Phum005307.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pediculus humanus
Gene Symbol
-
Assembly
GCA_000006295.1
Location
NW:911304-918171[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 31 0.0041 0.27 11.1 0.6 1 23 13 35 13 35 0.96
2 31 0.0028 0.19 11.6 0.2 1 23 119 141 119 141 0.97
3 31 0.00012 0.008 15.9 0.8 1 23 147 170 147 170 0.96
4 31 3.3e-05 0.0022 17.6 0.4 1 23 176 198 176 198 0.97
5 31 0.00098 0.066 13.0 0.2 1 23 203 226 203 226 0.97
6 31 0.0011 0.073 12.9 3.2 1 23 232 254 232 254 0.98
7 31 3.9e-05 0.0026 17.4 0.3 1 23 260 282 260 282 0.99
8 31 1.7e-07 1.1e-05 24.9 0.7 1 23 288 310 288 310 0.99
9 31 0.011 0.71 9.8 0.0 1 14 316 329 316 330 0.90
10 31 1.3e-05 0.00085 19.0 3.6 1 23 340 362 340 362 0.97
11 31 0.0012 0.082 12.7 1.7 1 23 369 391 369 391 0.99
12 31 2.6e-07 1.7e-05 24.3 0.5 1 23 397 419 397 419 0.97
13 31 8.1e-05 0.0054 16.4 3.6 1 23 425 448 425 448 0.95
14 31 0.00018 0.012 15.4 0.8 1 23 459 481 459 481 0.98
15 31 0.001 0.069 12.9 0.3 1 20 487 506 487 508 0.94
16 31 6.7 4.5e+02 0.9 0.3 2 11 517 526 516 529 0.88
17 31 2.8e-06 0.00019 21.0 0.2 1 23 547 569 547 569 0.97
18 31 1.2e-07 8e-06 25.3 2.0 1 23 575 597 575 597 0.99
19 31 0.00021 0.014 15.1 1.1 1 23 603 625 603 625 0.96
20 31 0.00017 0.011 15.4 3.9 1 23 633 655 633 655 0.97
21 31 3e-05 0.002 17.8 1.0 1 23 663 685 663 685 0.97
22 31 0.00089 0.06 13.1 0.5 1 23 691 713 691 713 0.96
23 31 2.8e-05 0.0019 17.9 0.3 1 21 719 739 719 740 0.95
24 31 0.0026 0.17 11.7 0.7 2 23 749 771 748 771 0.95
25 31 3.5e-06 0.00023 20.7 0.3 1 23 777 799 777 799 0.96
26 31 6.5e-06 0.00044 19.9 4.7 1 23 805 827 805 827 0.98
27 31 0.08 5.4 7.0 1.4 1 23 833 854 833 854 0.95
28 31 0.00012 0.0081 15.9 0.3 1 20 859 878 859 881 0.95
29 31 5.8e-05 0.0039 16.9 0.3 1 21 887 907 887 908 0.94
30 31 0.00038 0.025 14.3 0.1 1 23 915 937 915 937 0.99
31 31 0.017 1.1 9.1 4.6 1 23 943 965 943 965 0.99

Sequence Information

Coding Sequence
ATGCTCATGCACAAActcaaaaaagaaatgaaaatattcgTGTGTTCTTGCTGCGGTATAAATTTCGAAAACGAAGATAATTTGTTGGAACATGAGAAAATGCATgcggaagaagaaaacgaagCTCTCATGAAGGGGGGCGAGGGCGAGGACGAGTGCGAGGATATAACGATTGTCGATAACATCAAAATGGAACCCTCCGATGGATCTCACATGATCGTCATGCCGATCGAAGAAGTCGAATGTAACGGATTGGAAGAAGGGGAAGAAGAGAATGTCGAGTGCGAAACAAGTATATCCGTTTTAAAAGACGAATATGCAATTATAGAAGTGTCGCAAGAGGAAGAAGGTGAATTTATATGCGGCGAATGTGGGAAAGAATGCGCGGACATACAATCCGTTAACTTGCACATGAAGGAACACATGGAATCTGAAATGTTTGAATGTTCCGAATGCAAGCAAGTTTTCAAATACAAACAATTGCTTCTTCAGCACGTTCAAAACGTTCACGAGGGTCACAGAGCTTACACATGTGACGTTTGTTGGGCGACGTTTTCGAGTAAAAATAGTTTGCGTAATCACAGAGTCATACATCTTTCCCTGAGGTACCCGTGCGAAGAATGCGGTAACGAATTTAAAGGACGAAGCGGACTTTATCTTCACAAGCAACGGGTTCACAGGGGTAAAAAAGATTTCGAATGTGATTATTGCGGTAAAACGTTTGCTTTAAAGTGCCAAAGAGATACCCACAGGCGGATACACACGGGagaaaaaccatttaaatGCGAAACTTGCGGAGCCGGATTCAGAGCTCAAAGCGGTCTGTACGCTCACAGGAAAACGCACACCGACGAAAGGCCTTACAAGTGCGAAATATGCGGGAAACGCTTGCGATTACCCTACAATCTTCGACTTCACATGAGGACACACACGGGTGAAAAACCATACGCGTGTGATATTTGCGGACGAGCTTTCTCACAACCGGGAGAttCTTTACATTCGCCATTTCCGAAAAAACACGTTTGCGACATTTGCGGTAAAGAATTCACGTTTAAATCCAATTATAATACTCATAAATACACACACATGGACATGCCTAGAAATTTCAAATGCACTCAATGCATGAGCGCGTTCAAAAATGCCAGaggattaaaaaatcatttgaaaactCACGACACggataaaaatttcgtttgcgAGATTTGCGGTAAAAAATTCACGACGacgatcaatttaaaaaatcacatgTCGGCACATTCAGATCTTCGACCCCATTATTGCGAAATGTGTCAGGGATCGTTCAAGAGAGCAAGTCATTTGCAACAGCATCAGAAAGAAGTTCACGGGGTTCACCAGTCGAAAATGGCGAGGAATTTTCCTTGCGATTCTTGCGATAATTCATTCACGACGAGCGAACGTTTGGAAGTGCATAAGAGAAAACACACGGGAGAATTACCATTTCAATGTAACAAATGCTGGAGAGGATTCGCGTCACAAATGGGTTTGAACGTTCATCACACTATGGGAGAATGTCAAAGTAAAACGTCATCTTGTAAAATTTGTCACGCGGAATTCAAACCTGGACAAGAGCCTTGCGTTCACCAACATTTTAGAACGTGTCACACGGACGAACGTCCGTTCGTTTGCGACGAATGCGGAAAAGCGTTTAAAGCTAAAAACACGTTACAAAATCATCAAGCCGTTCATTCCGATAGTCGACCTTATCCTTGTTCGTATTGCGATAAGAGATTTAGAAGGTCTGAACAATTGATGTTACACACGAGAACTCACACGGGTGAAAAACCTCACATTTGTAACTTTTGCGGACGGGGATTTGCTCAAATTGGGGATATGAAAAAACACAGGAAGATACATAACAGAAAACCACCCAAAACGCATACCTGTAATCAATGTAACGCAGCATTTACGACCCTCAGATCACTTAGACGACATTATTTCactcattataattataaagacAAAGAATTCATTTGTGAACTTTGTGGTAAAAGATTTGCTTATTCTAtgacattaaaaaatcataaattatcACATTCGGAGGAAAGGCCTCACATTTGTAGAATATGTGGTACATCTATGGTTAAAAAGGAATCGTTGGAAGCTCACATGAAAGAACATACCGGAGAGTTAAATTATCAATGTAAAGactgttataaaaaatttgcgaCAAATACGGgattaaatatacatatatcgATGGGAAAATGTTATCCACATGTTAAATCGTGTAACGTTTGCTTGAAAGATTTCAAAGGAAATGAAGATCTCAAAACGCATTTCCGTTTGGCTCACACGgatgaaaaacctttttcttgcGGAAAATGCGGAAAAGCGTTTAAAACGAAAGCTTCCCTTCAAATGCACGAGGATGTACATAACGATCTTCGACCTCACGAATGCGATCTATGTCAAAAAAGGTTTAGAAAGGccgaacatttaaaattacatataaGGACTCATACGGGAGAAAAACCACACGTTTGCGAAATATGCGGAAGAGggattaaaaaacaattggaAAAACACATAAAGAAACAACACAACGATGAAGTTTACCAATGTCCAagatgtaataaaatattaaaaacaaagggCACATTGAGAGAACACATGTGGATTCACACAGACCACAGGAGATTTATATGTGATATATGTGGTATGAGGTTTAAAAGAACAAGTAATTACCGTGGACACCTTAAGATACCCCCacaagaaaaaggttttcaatgTGAAGTTTGTGGTGTTAAacttaaatggaaaaataatttattggcaCACATGAGAATACACACAGGAGAAAAACcttataaatgtaaaatatgtGGTGATGGTTTTACATGTCATGGTTCACTTAGAACTCACATGTCTAAACATGGTAAGTGTCAATTGACCACCTATAGAATATTACAtttctaa
Protein Sequence
MLMHKLKKEMKIFVCSCCGINFENEDNLLEHEKMHAEEENEALMKGGEGEDECEDITIVDNIKMEPSDGSHMIVMPIEEVECNGLEEGEEENVECETSISVLKDEYAIIEVSQEEEGEFICGECGKECADIQSVNLHMKEHMESEMFECSECKQVFKYKQLLLQHVQNVHEGHRAYTCDVCWATFSSKNSLRNHRVIHLSLRYPCEECGNEFKGRSGLYLHKQRVHRGKKDFECDYCGKTFALKCQRDTHRRIHTGEKPFKCETCGAGFRAQSGLYAHRKTHTDERPYKCEICGKRLRLPYNLRLHMRTHTGEKPYACDICGRAFSQPGDSLHSPFPKKHVCDICGKEFTFKSNYNTHKYTHMDMPRNFKCTQCMSAFKNARGLKNHLKTHDTDKNFVCEICGKKFTTTINLKNHMSAHSDLRPHYCEMCQGSFKRASHLQQHQKEVHGVHQSKMARNFPCDSCDNSFTTSERLEVHKRKHTGELPFQCNKCWRGFASQMGLNVHHTMGECQSKTSSCKICHAEFKPGQEPCVHQHFRTCHTDERPFVCDECGKAFKAKNTLQNHQAVHSDSRPYPCSYCDKRFRRSEQLMLHTRTHTGEKPHICNFCGRGFAQIGDMKKHRKIHNRKPPKTHTCNQCNAAFTTLRSLRRHYFTHYNYKDKEFICELCGKRFAYSMTLKNHKLSHSEERPHICRICGTSMVKKESLEAHMKEHTGELNYQCKDCYKKFATNTGLNIHISMGKCYPHVKSCNVCLKDFKGNEDLKTHFRLAHTDEKPFSCGKCGKAFKTKASLQMHEDVHNDLRPHECDLCQKRFRKAEHLKLHIRTHTGEKPHVCEICGRGIKKQLEKHIKKQHNDEVYQCPRCNKILKTKGTLREHMWIHTDHRRFICDICGMRFKRTSNYRGHLKIPPQEKGFQCEVCGVKLKWKNNLLAHMRIHTGEKPYKCKICGDGFTCHGSLRTHMSKHGKCQLTTYRILHF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-