Phum005308.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pediculus humanus
Gene Symbol
-
Assembly
GCA_000006295.1
Location
NW:919346-928853[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 44 0.00011 0.0075 16.0 3.8 1 23 60 82 60 82 0.98
2 44 0.048 3.2 7.7 1.4 1 13 88 100 88 102 0.87
3 44 0.00034 0.023 14.5 5.7 1 23 126 148 126 148 0.99
4 44 4.7 3.1e+02 1.4 0.9 1 13 156 168 156 176 0.83
5 44 0.00076 0.051 13.4 3.1 1 23 194 216 194 216 0.97
6 44 2.1 1.4e+02 2.6 0.9 1 10 222 231 222 245 0.86
7 44 1.8 1.2e+02 2.7 0.8 1 10 272 281 272 284 0.86
8 44 0.00043 0.029 14.1 0.3 1 23 300 322 300 322 0.96
9 44 4.6e-05 0.0031 17.2 1.3 3 23 330 351 328 351 0.95
10 44 2.6e-06 0.00018 21.1 1.0 2 23 358 379 358 379 0.98
11 44 4.6e-05 0.0031 17.2 0.1 1 20 385 404 385 407 0.93
12 44 0.00031 0.021 14.6 6.4 1 23 413 435 413 435 0.98
13 44 0.0082 0.55 10.1 3.8 2 23 464 486 463 486 0.96
14 44 2.8e-06 0.00019 21.0 0.4 2 23 493 514 493 514 0.98
15 44 7.7e-07 5.2e-05 22.8 1.8 1 23 520 542 520 542 0.99
16 44 0.022 1.5 8.8 2.5 3 23 550 570 548 570 0.91
17 44 0.00079 0.053 13.3 1.5 1 19 576 594 576 598 0.96
18 44 6e-05 0.004 16.8 6.1 1 23 604 626 604 627 0.96
19 44 0.0001 0.0068 16.1 2.1 1 23 666 689 666 689 0.95
20 44 0.00014 0.0093 15.7 1.4 1 23 695 717 695 717 0.97
21 44 4.3e-05 0.0029 17.3 4.5 1 23 723 745 723 745 0.98
22 44 0.00083 0.055 13.2 5.7 1 23 751 773 751 773 0.97
23 44 1.9e-06 0.00013 21.6 0.2 3 23 781 801 779 801 0.97
24 44 0.00037 0.025 14.4 6.2 1 23 807 829 807 830 0.96
25 44 0.0031 0.21 11.5 0.1 3 23 837 857 836 857 0.97
26 44 0.092 6.1 6.8 3.0 1 23 886 908 886 908 0.96
27 44 0.00011 0.0072 16.0 0.9 1 23 914 936 914 936 0.95
28 44 0.00032 0.021 14.6 1.8 2 23 943 964 942 964 0.95
29 44 3.9e-05 0.0026 17.4 1.3 1 23 970 992 970 992 0.98
30 44 0.012 0.81 9.6 6.6 2 23 999 1020 998 1021 0.95
31 44 7.4e-05 0.0049 16.5 0.9 1 23 1027 1049 1027 1049 0.96
32 44 1.8e-06 0.00012 21.6 2.9 1 23 1055 1077 1055 1077 0.98
33 44 5.9e-07 4e-05 23.1 3.5 1 23 1094 1117 1094 1117 0.97
34 44 0.012 0.82 9.6 0.2 1 23 1123 1145 1123 1145 0.95
35 44 2.3e-06 0.00015 21.3 1.4 1 23 1151 1173 1151 1173 0.98
36 44 0.0017 0.12 12.2 3.4 1 23 1179 1201 1179 1201 0.97
37 44 0.0011 0.073 12.9 0.3 1 20 1207 1226 1207 1229 0.91
38 44 0.0015 0.1 12.4 4.0 2 23 1272 1293 1272 1293 0.98
39 44 3.1e-05 0.002 17.8 0.5 1 23 1299 1322 1299 1322 0.96
40 44 0.0058 0.39 10.6 0.1 2 23 1329 1350 1328 1350 0.96
41 44 0.00044 0.029 14.1 3.4 1 23 1356 1378 1356 1378 0.98
42 44 0.017 1.1 9.1 1.6 1 23 1384 1406 1384 1406 0.97
43 44 0.00064 0.043 13.6 4.8 1 23 1412 1434 1412 1434 0.97
44 44 2.6e-05 0.0018 18.0 3.1 1 23 1440 1463 1440 1463 0.95

Sequence Information

Coding Sequence
ATGCGGATGTGGGATTTCAAGGGGAGATTACCAAAACTGGACGTTTCATTTTACAGGTCGGAACGGAGGATGAAAGAAGGAAAGTGTGAAAttgtaacgaaaaataaaaaaagaaaatttcccaaAGAAATGGAATCGATATCCGTTCTTGGATCGAACGGAATTTTAAAAAGCATTTACAGATGTAAATTATGCGGACACAAAACGAATCGTAGCAACAATTTGAAAACTCATTTGCAAATACATAAGAGAGTCGTGGCGTACAAGTGCGAGAATTGCGGTAAAAGATATAGGAAAAGTCATGGAGACGATAAGAGTCATTTGACGAGAATGGAAATCGTTATGGAAAACATCGAAGGAcaaattaagaaattttacaGGTGTAAAATATGTCGTCACACGTCGAACAGGAgtaacaatttgaaaaaacatttgaaaagtCACGAGTCGGGAAGGGACGACGAATTTCCCTGCGACGATTGCGGCGGAAAATGTCGTCAGAGTCAAATTGTCAATTATCACGTGAAAGAAATCGAAGTCGTGACGACGCGTGACGGGAaggggaaaagtaaaaaattattttgttgtaaaatatGCGGGGAAAAATTTGGACGAATGATGAATTTCAGATCTCACATAACGTCACACAAACCCATAAACATATTCGTGTGCAAACTTTGCGGAAAGGAATACCTGTgcgaaaaaggtttaaaagaaCATTCGTTGAGTGCTCACGGGAAAATCGATGACGGGgatgttgatgataatgataatgataatgatgatggtggcggTGCGCCTTTGAAATTCCCTTACAAATGCGAATATTGCGATCAATTGTTTCCCGAGAAAATTATATGCGACGAACATAGGCAAATCCACGGAGGAGAAAAACCTTACATATGCACGATTTGTAAATCCGCGTTTCGAACTCAAAGCTCTCTTTATTTACACGCCGAAATTCACATGAAAAATacgGAAATCGATTGTCAAATATGCGATAAAACGTTCGGTAGTAAAAGTTTTCTTCACAGGCACGTTCAAAGCGTTCACGAAAGGATAGTCAAAGCCAAATGCGACGTGTGCGATAAAACGTTTACGGACACGTCCAATTACAAGCAACACTTGTTGATACACGCGGGAATCAAATCGTACATGTGTCAAATATGCGGAAAGGGATTCGTTCAACCGCAGGGATTGCGAATGCACATGCCCTCTCACTCGTCCGAATATCCATATTCGTGCACGTTTTGCCCGAAAAAATTCCGGAGAAAACAACATTTCGAATTGCACACGATGAAACACGcggggggaaataataataataaatcgcaTCAAGACATTAtggaaatattatcatcagtCGACGACAAACCTTCATCATCGCTTATATGTCACTTGTGCgcgaaagaatttaaaaaagtgcACCTCCTTCACGCTCACATACGTCGCGTTCACGAGAGAGTCGTCGTCGCGAAATGCGACGTTTGCGGACGTGATTTTCGCGATGCATCGAATTATTCGAGTCACATGAAAATCCATTCGGAAGTCAAATCGTACGTTTGTCAAAATTGCGGCAAGTGTTTCGCACAGCTCCAAGGTTTGAAAATACATCAGAGAACGCACACGTTGAACTACCCGCATTTGTGCATGGTGTGCGGGAGAAGGTATCGGACCAGGCAACATTTGGATCAACACGCGTCCGCGCACACGGAAGAAAGGCCCTACGAGTGCGAATCGTGcggaaaatatttcaaaacgaGACTTCATTTGAAAGCACACAGTTGGATTCACAGCGATAAATTTCGTTACTATTGCGATTACTGTCGGAAAGGTTTCAATAATTCGAGTCATTTGAAACTCCACGTGAAAAATCATCACGTCAACGTGAACGTGATACAAGCGAGAATCGAAACGGTGGGTCAACCCGAGCCCACGATCGTGGAATTACAGGGATATGCGAGACACATGAAAAATCATTTGGGTGACAGGTCTCACATGTGTCACATATGCGGTAAAAGTTTCATTGAGAAAAAAGACATTTCGCGTCACGTGAGAGAAGTTCACGATAAAATCAAAAGGTACAGTTGCGAATATTGCGGGAGATCGTTCGCGACGAAAAACACGAGAAACGATCACAGAACGATTCACACGGGAGAAAGAACCTACGTTTGTCACATTTGcggtaaaacatttaaaacggCCAATTGCGTGTACGTGCACAGGAGATCGCACACGGATTACGCACCTCACAAGTGTCACTCTTGCAACAAATCCTTTCGCACGAGGCAAAGGTTAAACAATCACGTGGCCATACACACGGGCGAAAAACCCTACGGATGTCAAATTTGCGGTAAAAGATTCATAACGAAATCTCAATTGAATGGTCACATGGAAATCCATTCCGTCGACAGACCGTACACGTGTTCGCACTGCGGAAACAAATACagcgttaaaaaatatttaagggtTCATTTGAAAACGCATCATCCGGAAATTGAAAATCCATGCGACATATGCGGTAGAAAGTTCGCTTTGAAAGCCGCGAGAGAAGATCACAGGAGGATACACACGGGTGAGAGACCGTTCGTTTGCACGACTTGCGCGAAAGCATCCCTGTACATCCACGGGAAAACTCACACGGATTCCTTTCCTCACTCGTGCGCGTACTGTTCGAGAAGGTTTCGATGGAGGCAACAGTTGTTGAGTCACGTCACGACTCACACGGgtgaaaaaaaacacttttgcGACGAGTGCGGAAAAGGTTTCGGTGTGAAAAACGATTTGACTCGTCACAAATTGGTGCATTCGCAAGAGAAACCTTTTCTGTGCTTGACGTGCGGCCTTTCGTTCGGTCAAAAAAGATATTTGAAAAAGCATTTTAGAATACACACGATGGAGTATCCGTTCGAGTGCAACACGTGTGGGAAAAAAGTTCGAACGACGGGCTCGTTGAGATCTCATCAAAAGCTACACTACGACAGCAAGGTGCTCAAGTGCGATTATTGCGACGAGAGATTTCGATTCAATCAACAGAGGATTCATCACACGAGACGGCACCACACGAAGGAAAAACCTTTCGCGTGTCAATTGTGCGATAAAAAATTCGAAGTCAAACAAGAGCTCAAACGTCATTTGTTCGTTCACACGTCGGTTAACAGTTTCGAATGCGATTATTGCGGAAGGAAATTCAAACAAAAGAGATATTTGTTAAATCATCTTAAATCACATTCGGAATTGCTTTTGAGACACGGGAAAACACACGAGAGGAAAAAACAATTCATATGTCACTTGTGCGGAAAAGAATTCAAACACAATTACGCGTTGCAAAGACACGTGAGAACGGTTCACGAGAACAAGAGAGATTTCGAATGCGATTTGTGCGGGAAAGCGTTCATGGAAAAAAGCGTGAGAGACGATCACAGGAGAATACACACGGGAGAATGTCCCTACGTGTGTCCCACGTGCGGGAAAGCGTTCAAAACTATGGCGTCGTTGTGCACGCATAGGAAAATACACACGGATTCGTTTCCGCACGAGTGCACGTTCTGTCCGAAAAGGTTCCGATTCAAACAACAGCTTTTGGGTCACCTGACCATGCACACCGgggagaaaaaacatttttgtgaTATTTGCGGAAAAGGTTTCGGCGTTCGGTGGGATTTAACCCGACACAGGCCGATACATAATAAATCGAAGGATTTCGTTTGCGCGATAAAGAAGGAACCTttggatgttgttgttgttgacataaaggaatcaattgaaaaaaatagtaCCGGGATGGgtgtaaaaaaagaatcggATTCGCGGAAATGCGGGAaatgcgaaaaaatttttcacaacgaaaaattattaaagcgTCACGAGAAAACTCATCTCGGATTGGGTTTGTTCATTTGTCACGTTTGCGGTAAATcccttaataaaaaaggagCTTTGGTACGTCACGTGAGAAACGTTCACGAGGGAAGACGGGATTGGATATGCGATTTGTGCGGGAAAGGATTTCCCGAGAGATCCGTTCGAGAAGATCACAGGCGGACTCACACGGGAGAATGTCCGTACGTGTGTCACGCgtgcgggaaaaaatttaaaactatgGCGTCGCTGTGCATACACAGCAAAGTTCACGTGAACGATTTCCCTCATCGGTGTCCCTATTGTCCGGGTAAATTCAGGTGGAAAACTCAATTGAACGGTCATTTGACGACTCACACGGGAGAGAAAAAGCACAAATGCGACGTGTGCGGGAAAGCGTTCGGAGTGAAATGCGATTTGAACAGGCACAAACACGTTCACTCGAATGAGAAACCCTTTTCTTGTTCCATGTGCGACTATAGTTTTTCACAAAAGCGATACCTCAAAAAACACGAGTTGTCGAAACATGGCGGAAAAGACGTCGCGAAAAATCCCAAACAAATAcgcgaatga
Protein Sequence
MRMWDFKGRLPKLDVSFYRSERRMKEGKCEIVTKNKKRKFPKEMESISVLGSNGILKSIYRCKLCGHKTNRSNNLKTHLQIHKRVVAYKCENCGKRYRKSHGDDKSHLTRMEIVMENIEGQIKKFYRCKICRHTSNRSNNLKKHLKSHESGRDDEFPCDDCGGKCRQSQIVNYHVKEIEVVTTRDGKGKSKKLFCCKICGEKFGRMMNFRSHITSHKPINIFVCKLCGKEYLCEKGLKEHSLSAHGKIDDGDVDDNDNDNDDGGGAPLKFPYKCEYCDQLFPEKIICDEHRQIHGGEKPYICTICKSAFRTQSSLYLHAEIHMKNTEIDCQICDKTFGSKSFLHRHVQSVHERIVKAKCDVCDKTFTDTSNYKQHLLIHAGIKSYMCQICGKGFVQPQGLRMHMPSHSSEYPYSCTFCPKKFRRKQHFELHTMKHAGGNNNNKSHQDIMEILSSVDDKPSSSLICHLCAKEFKKVHLLHAHIRRVHERVVVAKCDVCGRDFRDASNYSSHMKIHSEVKSYVCQNCGKCFAQLQGLKIHQRTHTLNYPHLCMVCGRRYRTRQHLDQHASAHTEERPYECESCGKYFKTRLHLKAHSWIHSDKFRYYCDYCRKGFNNSSHLKLHVKNHHVNVNVIQARIETVGQPEPTIVELQGYARHMKNHLGDRSHMCHICGKSFIEKKDISRHVREVHDKIKRYSCEYCGRSFATKNTRNDHRTIHTGERTYVCHICGKTFKTANCVYVHRRSHTDYAPHKCHSCNKSFRTRQRLNNHVAIHTGEKPYGCQICGKRFITKSQLNGHMEIHSVDRPYTCSHCGNKYSVKKYLRVHLKTHHPEIENPCDICGRKFALKAAREDHRRIHTGERPFVCTTCAKASLYIHGKTHTDSFPHSCAYCSRRFRWRQQLLSHVTTHTGEKKHFCDECGKGFGVKNDLTRHKLVHSQEKPFLCLTCGLSFGQKRYLKKHFRIHTMEYPFECNTCGKKVRTTGSLRSHQKLHYDSKVLKCDYCDERFRFNQQRIHHTRRHHTKEKPFACQLCDKKFEVKQELKRHLFVHTSVNSFECDYCGRKFKQKRYLLNHLKSHSELLLRHGKTHERKKQFICHLCGKEFKHNYALQRHVRTVHENKRDFECDLCGKAFMEKSVRDDHRRIHTGECPYVCPTCGKAFKTMASLCTHRKIHTDSFPHECTFCPKRFRFKQQLLGHLTMHTGEKKHFCDICGKGFGVRWDLTRHRPIHNKSKDFVCAIKKEPLDVVVVDIKESIEKNSTGMGVKKESDSRKCGKCEKIFHNEKLLKRHEKTHLGLGLFICHVCGKSLNKKGALVRHVRNVHEGRRDWICDLCGKGFPERSVREDHRRTHTGECPYVCHACGKKFKTMASLCIHSKVHVNDFPHRCPYCPGKFRWKTQLNGHLTTHTGEKKHKCDVCGKAFGVKCDLNRHKHVHSNEKPFSCSMCDYSFSQKRYLKKHELSKHGGKDVAKNPKQIRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-