Basic Information

Insect: Pediacus dermestoides
Gene Symbol: topi
Assembly: GCA_963942485.1
Location: OZ012629.1:11249331-11252941[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0023 0.21 12.5 2.1 2 21 113 132 112 133 0.94

2 14 3.8e-06 0.00035 21.3 0.6 1 23 158 180 158 180 0.97

3 14 0.0098 0.89 10.6 2.0 3 23 188 208 187 208 0.95

4 14 0.19 18 6.5 0.3 2 12 227 237 226 240 0.89

5 14 0.0017 0.15 13.0 1.1 2 23 309 330 308 330 0.96

6 14 0.56 51 5.0 0.0 1 13 336 348 336 357 0.80

7 14 0.082 7.5 7.7 2.7 2 21 373 392 372 396 0.83

8 14 0.0026 0.24 12.4 0.4 1 23 534 557 534 557 0.97

9 14 0.011 1 10.4 0.2 1 23 561 583 561 583 0.96

10 14 7.8e-07 7.1e-05 23.5 2.4 1 23 589 611 589 611 0.98

11 14 0.022 2 9.5 0.2 1 23 617 642 617 642 0.96

12 14 0.14 12 7.0 3.3 1 23 648 670 648 670 0.86

13 14 4.9e-05 0.0045 17.8 0.5 3 23 678 698 676 698 0.97

14 14 3.2e-05 0.0029 18.4 1.4 1 23 704 727 704 727 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0023	0.21	12.5	2.1	2	21	113	132	112	133	0.94
2	14	3.8e-06	0.00035	21.3	0.6	1	23	158	180	158	180	0.97
3	14	0.0098	0.89	10.6	2.0	3	23	188	208	187	208	0.95
4	14	0.19	18	6.5	0.3	2	12	227	237	226	240	0.89
5	14	0.0017	0.15	13.0	1.1	2	23	309	330	308	330	0.96
6	14	0.56	51	5.0	0.0	1	13	336	348	336	357	0.80
7	14	0.082	7.5	7.7	2.7	2	21	373	392	372	396	0.83
8	14	0.0026	0.24	12.4	0.4	1	23	534	557	534	557	0.97
9	14	0.011	1	10.4	0.2	1	23	561	583	561	583	0.96
10	14	7.8e-07	7.1e-05	23.5	2.4	1	23	589	611	589	611	0.98
11	14	0.022	2	9.5	0.2	1	23	617	642	617	642	0.96
12	14	0.14	12	7.0	3.3	1	23	648	670	648	670	0.86
13	14	4.9e-05	0.0045	17.8	0.5	3	23	678	698	676	698	0.97
14	14	3.2e-05	0.0029	18.4	1.4	1	23	704	727	704	727	0.97

Sequence Information

Coding Sequence: ATGAATAAATCTGatgataatattataataaaagtccACAGAATAACCGATGATGGCCAAATTACATCCATAAGGTATGAGGATGATCTGTACGCAACTGAAGAAATTTCCACGAGCTCTTATATGCCGCTGGAAAgccttaatttaaatttgatggaAGCAGCAGATGAATCCAAATTAAATCTAGTCTACACAAATCTCGAACTGGTAGAAGGTGAATTACGGTGTTTTAAAATTGAGGATGTTTACTACATGGACGCACCAAATACCAACGGGGCAGTAGAACGCAAACAGCTACTAAATTTCACGACAAGCCTAAACATCCCAACAATGATCCGGTGCCAAAACTGCGAAACAAACTTTCCTACTAAATACCAATACCAAAGACACCAGTGTGAGTTTAACGCGGAAAAAGTCGTTTTAAAACCAGATGCGGATTTCAAAGACGTTGACAAAGGAGTGCGTATTAAATATGATTGTTCCACTTGCGGTAAGCTATTTGTTAGCAAAAATAATCTGGAACGGCATCAGGCTAGTCATGAGAATACGAAACTCAATATTTGTGAACATTGCAACAAGCAATTTGTCAGTGAAAATCGTTTACGGATCCACAAGGAGAACCACTGTAAAAAAGCGGGGGATATTTCGAAATTCTACCGGAGCGATGTGACTGTCTGGAAATGCAAAAAGTGCCATGAAGTGTTCTCCTCGGTGGCCACGGCAAGTTTTCACGTGGAAATTTGCAACGAAATAATCGAATTGAACTACAATAACCACACGTCGCTGATGAAAAGCGACCAAAAAGAGCTGGAGTTTCTCCAGGAGGAAATAAAGAACGTCACCTCGCTGGTGATGAATGGAGACATCGGAAATCAACAACAGGATAACAaggatattgaaaaaattttgacagaaATCCTGTTGCAATGTGAGTTTTGCAATCGCACGTATGCTGacaaaaatttgcttttaatgCACTCAAAAAAGCACACCACTGACAAAAACTACGAATGCGTCAACTGTGATGAAGTTTTCGATTCCTACGCAGTGGCCGCTCAACACTGGATGAAAAAATGCTCGGAATTTGCCAATTTATTCTACTTACCCAAACTAACTTACTGTGAATATTGCGACAGAACTTTCAAATCCCACGAAATTCTCTACAcgcacaaaataaaaaagaaacactACACGCCCAAAATGCATATTAACACCTCGTTGGAAAACAACCCAACAGAGGAATCCACTTCACAGTTTTCCAATAGCAGCAACAAAGACAAATTAAGCGAAAGCAAAGACAACATAAACAAACTAATTGAGGATGTCCTGAAAACTTTGGATGTACCCATGAATAAAATCAACAGCAACGAAATAAGAGATGACGAGGAAAGCAATAACGATAAACCAGAAAACGAATCCACTGGAACCATGCAGATTAAAAGCGAAAACCAAAGCGAATCATCCGGAACTAGCCTAGTCCCCTCAGTAGAAAACGAGGAGTGCACCGGAAAAAAGAAACGGGGGCGCAAGCGACGCTGGTCCAAACAAGGCGTTAAAATCGCAAAGAGAATTTGTGCTGTAGTTGACGAAGGGTTCAAGTACCAATGTGAACGTTGCGTTAAAACATTCGACACGGTTCTAGACTTGGAAACGCACCGGGAGAAGGAGCATGCCACTATATTCAACTGCGAAGAATGCGGACAGGTTCTCCACAGTGCTAAGGCTCTGTTAATCCATAGCAGAGCCCACAAGAGTTTAAAGCCTTATGTATGCGATACCTGCGGACGAAGTTACTCACAGACTTCGCATCTTTGGCAGCATATGCGATTCCATCAGGGTATAAAGCCGTTTGCTTGTCCACATGAAGGATGCGAGGCGCGCTACACGATAAGACCCGACCTTAAGGATCATATTCGTAAAGTTCATACAAGAGAACGTCCATTTAAATGCAATGTATGCAATAAATGTTTCCTTACTGGATCTGTTTATTACCAGCATAGGCTCATCCATACAAACGATAGAAGATATGGATGTGATGTTTGTCAGAAGCGGTTTTTTCGTGCTGATGCTTTGAATAATCACAAAAGAATTCACACAGACGAACGGCCTTATGCTTGTACAGTTTGTGGCAGGGAATTTCGGCAGAAGGGCGATCGAAACAAACATTTCCGCACCCAGCACCCAGAAGCCCTTGgcaatatttaa
Protein Sequence: MNKSDDNIIIKVHRITDDGQITSIRYEDDLYATEEISTSSYMPLESLNLNLMEAADESKLNLVYTNLELVEGELRCFKIEDVYYMDAPNTNGAVERKQLLNFTTSLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKPDADFKDVDKGVRIKYDCSTCGKLFVSKNNLERHQASHENTKLNICEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCKKCHEVFSSVATASFHVEICNEIIELNYNNHTSLMKSDQKELEFLQEEIKNVTSLVMNGDIGNQQQDNKDIEKILTEILLQCEFCNRTYADKNLLLMHSKKHTTDKNYECVNCDEVFDSYAVAAQHWMKKCSEFANLFYLPKLTYCEYCDRTFKSHEILYTHKIKKKHYTPKMHINTSLENNPTEESTSQFSNSSNKDKLSESKDNINKLIEDVLKTLDVPMNKINSNEIRDDEESNNDKPENESTGTMQIKSENQSESSGTSLVPSVENEECTGKKKRGRKRRWSKQGVKIAKRICAVVDEGFKYQCERCVKTFDTVLDLETHREKEHATIFNCEECGQVLHSAKALLIHSRAHKSLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCNKCFLTGSVYYQHRLIHTNDRRYGCDVCQKRFFRADALNNHKRIHTDERPYACTVCGREFRQKGDRNKHFRTQHPEALGNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -