Pder016413.2
Basic Information
- Insect
- Pediacus dermestoides
- Gene Symbol
- lola
- Assembly
- GCA_963942485.1
- Location
- OZ012630.1:174741-181193[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.1e-06 0.00038 21.2 0.9 1 22 42 63 42 63 0.94 2 13 3.6 3.3e+02 2.5 2.3 1 12 70 81 70 83 0.83 3 13 0.00026 0.024 15.5 0.5 2 21 85 104 84 105 0.94 4 13 6.4e-07 5.8e-05 23.7 2.6 1 22 113 134 113 134 0.96 5 13 0.085 7.8 7.6 2.4 3 19 147 163 145 166 0.88 6 13 1.3e-05 0.0012 19.7 5.0 1 23 174 198 174 198 0.92 7 13 0.00046 0.042 14.7 0.9 3 21 207 225 205 226 0.95 8 13 1.4e-06 0.00013 22.7 3.1 1 22 234 255 234 255 0.96 9 13 0.00039 0.035 15.0 2.0 2 21 269 288 268 289 0.94 10 13 4.7e-06 0.00043 21.0 2.6 1 23 297 320 297 320 0.96 11 13 0.0005 0.046 14.6 3.4 1 21 330 350 330 351 0.94 12 13 8.8e-05 0.008 17.0 0.8 1 21 367 387 367 388 0.95 13 13 0.00012 0.011 16.6 5.0 1 23 398 421 398 421 0.91
Sequence Information
- Coding Sequence
- ATGTGGACAGAAGCCGAAGTTTTCTTGCACACTATGCCCAAAGAATACGCTGTACCAAGTGCGATAGAGTCTACAAACGCCTTAGTGAGCCATCTTACGTACGAATGTGGGAAAGAACCACAGTTTCCTTGTAACAAATGCGGAAAACTTTTCAAGCAAAAATCCAGTATGAACAGACATATAACAACATGCAAAACGCAGCCAACGTTTAGTTGCAAAAAATGCCCAAAAAAACGGACACAACACAAAATACGCTGTACCAACTGCGATAGAATGTACAAACGCAAACGCGCCTTAGTGAGTCATCTTAAGTACGAATGTGGGAAAAACCCACAGTTTTCTTGTAACAAATGCGGAAAATTTTTCAAGCAAAAATCCAGTATGAACAGACATATAAAAACATGCAATTATTCTATTGTTTTAGTCTTGTACTTTGGATGTGACGGTTGTGGTAGAAAGTACAAACACAGAAGTGGTTTACACTGTCACAAGAAATATGAATGCGGGAAGGCCCCACAGTTTACCTGTGAAAACTGCGGAAGAAAATTCCATTTCAAATCGAACTTAACCAgacatttaaaaagatatttacaCAAGGATGAAGCATGTTCCTTCGGATGTAGCCGTTGTGGCAAACGTTATAGACAAAAGAGCACGTTAGGTAGCCACCAAAAATACGAATGCGGCAAGGCGCCACAATTTGCTTGCAATCGCTGCCCAAAGCGTTTCCACCAAAAGTCCAATTTGAAACGCCACATGAAAACGTGCTGGATTTATCCAAAAAGTGTCGCTTTTAAtccTATCCATTGTGAGATCTGTGGAAAGAACTACAGACACAAGAAGTCCATGTGGAACCATCAGAAATACGAATGTGGAAAGGATCCGCAGTTTACATGCGAGCTATGCCAGAAGAAGTTCTATCAAAAAGGAAACTTTAAACGGCATTTGAATTTGGTTCATAATGACGAATGTGAAAAGGGTTCTCAATATAACTGCGATACCTGTCAGAAGTCCTACAGGCACAAGAGGTCGCTTAGATCTCATGAAAAATACCAATGCGGGCAAAGTCCGCAGTTTTCTTGTGATCTATGTCCCCCGTATAAATGTGAGGTTTGTGACAAGAGTTACGCCAAACAAAACTCGCTTTATGCTCATAAAAAATACGTGTGCAACTATGGTTCCAATAGGGAgcataaatgcaaaatttgtggTTATGTTACTAgatacaaatataatttgaagaGGCATTTCACTCAATATCATactaaaaacatgaaaatgtag
- Protein Sequence
- MWTEAEVFLHTMPKEYAVPSAIESTNALVSHLTYECGKEPQFPCNKCGKLFKQKSSMNRHITTCKTQPTFSCKKCPKKRTQHKIRCTNCDRMYKRKRALVSHLKYECGKNPQFSCNKCGKFFKQKSSMNRHIKTCNYSIVLVLYFGCDGCGRKYKHRSGLHCHKKYECGKAPQFTCENCGRKFHFKSNLTRHLKRYLHKDEACSFGCSRCGKRYRQKSTLGSHQKYECGKAPQFACNRCPKRFHQKSNLKRHMKTCWIYPKSVAFNPIHCEICGKNYRHKKSMWNHQKYECGKDPQFTCELCQKKFYQKGNFKRHLNLVHNDECEKGSQYNCDTCQKSYRHKRSLRSHEKYQCGQSPQFSCDLCPPYKCEVCDKSYAKQNSLYAHKKYVCNYGSNREHKCKICGYVTRYKYNLKRHFTQYHTKNMKM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -