Basic Information

Insect: Pediacus dermestoides
Gene Symbol: ZFX
Assembly: GCA_963942485.1
Location: OZ012628.1:8199188-8207156[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0045 0.41 11.6 0.9 1 23 91 113 91 113 0.97

2 25 0.00014 0.013 16.4 0.2 1 23 119 141 119 141 0.98

3 25 0.00027 0.025 15.5 0.3 2 23 147 168 147 168 0.97

4 25 0.00043 0.039 14.9 0.1 1 23 174 196 174 196 0.97

5 25 0.4 37 5.5 0.5 2 23 207 228 206 228 0.95

6 25 4.4e-06 0.00041 21.1 0.6 1 23 253 275 253 275 0.97

7 25 2.1e-06 0.00019 22.1 0.8 1 23 281 303 281 303 0.98

8 25 4.8e-05 0.0044 17.8 1.4 1 23 309 332 309 332 0.96

9 25 0.13 12 7.0 3.7 1 23 342 365 342 365 0.97

10 25 0.00085 0.077 13.9 7.0 1 23 444 466 444 466 0.98

11 25 9.1e-07 8.3e-05 23.3 0.9 1 23 472 494 472 494 0.99

12 25 0.54 49 5.1 1.9 1 23 500 522 500 522 0.96

13 25 0.012 1.1 10.3 0.2 1 23 530 553 530 553 0.92

14 25 5.9e-07 5.4e-05 23.8 0.9 1 23 605 627 605 627 0.98

15 25 5.8e-05 0.0053 17.6 0.8 1 23 633 655 633 655 0.98

16 25 9.2e-06 0.00084 20.1 1.4 1 23 661 683 661 683 0.97

17 25 0.00012 0.011 16.6 2.2 1 23 689 712 689 712 0.98

18 25 0.00049 0.044 14.7 2.8 1 23 1002 1024 1002 1024 0.98

19 25 5.7e-07 5.2e-05 23.9 2.8 2 23 1032 1053 1032 1053 0.98

20 25 3.3e-05 0.003 18.3 2.0 1 23 1059 1081 1059 1081 0.98

21 25 0.00024 0.022 15.7 0.1 3 23 1090 1110 1088 1110 0.96

22 25 0.0072 0.66 11.0 1.7 1 23 1116 1139 1116 1139 0.97

23 25 0.00037 0.034 15.0 1.8 1 23 1277 1299 1277 1299 0.98

24 25 0.0015 0.14 13.1 0.1 1 23 1305 1327 1305 1327 0.98

25 25 0.0045 0.41 11.6 0.7 1 23 1333 1356 1333 1356 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0045	0.41	11.6	0.9	1	23	91	113	91	113	0.97
2	25	0.00014	0.013	16.4	0.2	1	23	119	141	119	141	0.98
3	25	0.00027	0.025	15.5	0.3	2	23	147	168	147	168	0.97
4	25	0.00043	0.039	14.9	0.1	1	23	174	196	174	196	0.97
5	25	0.4	37	5.5	0.5	2	23	207	228	206	228	0.95
6	25	4.4e-06	0.00041	21.1	0.6	1	23	253	275	253	275	0.97
7	25	2.1e-06	0.00019	22.1	0.8	1	23	281	303	281	303	0.98
8	25	4.8e-05	0.0044	17.8	1.4	1	23	309	332	309	332	0.96
9	25	0.13	12	7.0	3.7	1	23	342	365	342	365	0.97
10	25	0.00085	0.077	13.9	7.0	1	23	444	466	444	466	0.98
11	25	9.1e-07	8.3e-05	23.3	0.9	1	23	472	494	472	494	0.99
12	25	0.54	49	5.1	1.9	1	23	500	522	500	522	0.96
13	25	0.012	1.1	10.3	0.2	1	23	530	553	530	553	0.92
14	25	5.9e-07	5.4e-05	23.8	0.9	1	23	605	627	605	627	0.98
15	25	5.8e-05	0.0053	17.6	0.8	1	23	633	655	633	655	0.98
16	25	9.2e-06	0.00084	20.1	1.4	1	23	661	683	661	683	0.97
17	25	0.00012	0.011	16.6	2.2	1	23	689	712	689	712	0.98
18	25	0.00049	0.044	14.7	2.8	1	23	1002	1024	1002	1024	0.98
19	25	5.7e-07	5.2e-05	23.9	2.8	2	23	1032	1053	1032	1053	0.98
20	25	3.3e-05	0.003	18.3	2.0	1	23	1059	1081	1059	1081	0.98
21	25	0.00024	0.022	15.7	0.1	3	23	1090	1110	1088	1110	0.96
22	25	0.0072	0.66	11.0	1.7	1	23	1116	1139	1116	1139	0.97
23	25	0.00037	0.034	15.0	1.8	1	23	1277	1299	1277	1299	0.98
24	25	0.0015	0.14	13.1	0.1	1	23	1305	1327	1305	1327	0.98
25	25	0.0045	0.41	11.6	0.7	1	23	1333	1356	1333	1356	0.97

Sequence Information

Coding Sequence: ATGGATTCGGATCAACTACAGGCAATTCTTACGATACCAGACGACACATTCAACCTCAACACCGAATTAAACGAAACAGTAACAGCGTATTTCAAAGATTCTTCCATTGAGGGTGCCACAGAAAACaagcaaatattttacattacaTCTAACAACCAATTCCCTCTTACTCAAATGAGTAACTTAATTCACGTACCAAGGCAACAAATTTATCTGAAACCACCGTCGAAATTACAAGAGGAAATACAGCCAAGCCCCGTAATGACACCGTATAAATGCATAAAATGCAACAAAGAGTTCGACACGATTGCTCTGTATAAAAAACACATGTTGTGGCATCGGAATACTAAGAAATATCCTTGCTCCAAGTGCTCACAGGGTTACAACAACGAAAGGAATCTTATAATCCATATGGCGACTCATCCAGAAGGAAAACCTACTTGTCCAGTTTGTAATCTCTCCTTTCAAAGGTTAGCTAGTCTTAAGTCGCATTTAATGCTGCATCAAGTGGATGAGGGTTTTGTTTGCGAGGAATGTAAAGCAGAGTTTGACAAAGAGGATGAGTTAATTAAACACATGGAACTTCATATTAAACTAAACGAAGAGCCCCCGAACTTAATATGTCCTTACTGTAAAGTTAGTCACGAAAATCCAATAGAGTATAAGAAGCATATTTCGCAGCATGTTAAACTAAGGAAGATGGTGCTGAAAGGCAAGAGGTTTAAGAAGAAACCGGCGAGCAAGATGCAAAACAAACACGTCTGCGTTATTTGTAGTAAAAGCTTTATAAAAGCGTCGCTTTTGGAACGCCATTTAAGGATACACACTGGGGAAAAACCTTTTGTGtgCAGGGTATGCAATCGCGGTTTTACTCAAAATGGAACTCTACGCATTCACATGAAAACACACATCGATAGCCGTCCTTATCACTGCACACTTTGTCCAGCAAGGTTCACCCAAAAAGgtaATTTGAAGGTGCACATAGACAAAACCCACACAGCTGCTAGTATCGGCTCCAAGATCTACAAATGTACTTTGTGCATGtgcattttcaaaaaagttggCTCGTTGAACACGCACATGAGCCGATTTCATTCCGAGAATATAGGCATGGTTATGGATAAATTAAAAGAGTTGGAGGAGCAGCTTAATCCAAGTAAACCTAAGAAGGATGTACTGGAAAAACCACCACCAGCACTTGGTGATACTCAGAAAGAAGAACAGGATGAAGTCGTCGATTCTGGTTTAGTACGTTTAACAGAATCGGGCCAGGATGGTACCATCAAACGGCATTTAGTTAAAAGGGAAAGAGTTGGGGTTGTTTGGTGGTACTGCTGTAGTTACtgttcgaaaaaatgcaaaaagcCGTCGGATTTAATTCGGCATTTTCGCGTACATACCAAGGAAAAACCCTTCCAAtgtcaagacTGTGGTGTAACTTTTACCTTAAAATCGACTTTGGTATCGCACATGAAAACACATGCAGCTTTGAAGGAGTATAAATGTGGTAAATGCGAGGCTGTGTTTACTTGTGTGAGAAGTTTAAGTCTTCATTTAAGCAAACACGAGAAAATGTACACTACAAACTATCAGTGcaatatttgtaataaaatgtatggTTCTTTGGAAGAAGTAAGTTTACATCGAGTTAGTGATCATCTAGACGACAGTAAACCACTAGAGAATCTAGTTAAAGTGGTGCTGAAACGACCTGTACATGAACCACAACCAGGAGTGATAAATCCGGCGAAGCCACGTAACAGTCTAATAAACCTACCGATCAAAGCCAACAATGCGGATACTCCTCGCCCTTTCCAATGCACCATATGCGATGCACGGTTTACCAGGCAGATAAACCTGAAACGCCATGTAAAAGTCCATGAGAACGACAGACAGTACAAATGCGACATGTGCCCCAGGGCTTTTATTTCGTCGTATCGCTTAACCGAACATTTGAAGTACCACAACAATATAAGAAAATTCGAGTGTCAGATATGCCAGAAGAAATTTGTAACGTCCACTTTGCTCAAACGCCACGTTTCATCGCACAGCTCAAAGAGACCTTATACTTGTCCTTATTGCAGCAAGAAATTCAAATCGTTGATGTTGACTAAGACCCACATAAGACGCGTGCATAAACTCCAAATTACACAGACTTTAGCAGAAGACAAGGATGAAAACCCAGACTCCTGTGAAGCTCTATCGACAGATTTGGATAAAACAACTGGGGATACATCGCTTATCTCCCCTGAAAATACCACAGTAAAAATTAGCATTGGAACCACGGACAGCCCTTCGGACTCGTCTAATGTAGTCGTGGGTCTAAGCGAACAGTTCTTCCAAATACCTCAAAATACCCTTCAAATTTTGAACCAGAATGTGGAGGAGCAAAATCAACCGCAACCTGATCCACAAGTCTTTCAAACAATTTACGTTAATTACGACGATTTGCAATTAACAGACTCAGAATTGTGTAACAATGTTCTAGGACAAATCAAACTACATAACGCCGACTCGCTTTTGCTCAATGCAGCTTTGGAAGACACCACTGTTATCTTTAATATCGATGCCACGAAACTACAGCAGGAGCTCGAATTGAGCAACGATACGTTCAACGCTGCTAAACAAATTTACGATGAGAACAACATGGCGGATATCGTAGCGCGTATTTCGTCCAATAAAACTCAAGATTCGCTTCCGCTGCCTGATTTATCGTTAAGCTCAATTCAAAATGCTGTAGAAGGTGGTTTATGTTTAAACGGGGATTTGTTGGCTACTACCGATACAACACCGCAAAGCTTCTACTTCTCCCCTGATACATTGAACATGAACCCTGGGGAACAAACCCTTGATGAAACGGACTTAATTTGTATCAATTGTAATCAGGTGTTTAACTCTATAAAAGTGTTTAAGGCACATGAGTGTGGTAAGAAATTGTTGGATGAACCACTTCCACCGGAGGAAGAGAAGGAGTCACCACCAGTTGAAAAGAAAAAACCCGTATTCGAGTGCCATCTTTGTAAACTAACTTTTCCAAATCGTAATTGGTATAAACGGCATTTGGAGTCGCATGCCAAGGATGGTTCTATGAACACGTGCTCGTATTGTAAGAAGGAGTTTAAGAAGCCGTCGGATTTGaaaCGCCATCTTCGGACTCATACAGGAGAAAAACCGTACGCCTGCAAAAAATGCGACAAGAAATTTGCGTTGAAATCCACCCTAGATTCTCATACACGTACTCATGATTCCACTAACAAGTATGTGAATTGTGACGTTTGCAACGCGGTTTTCACAGCTAAGAGTAGCTTAAAAGTCCACATGTTTATACATGAAAAGAAAAAACCGTACATTTGCAATTTTTGCCCCTCGTCCTTCCGTACAGCTGCCCACAGGCGCGTCCATGAGCGCTCACAACACGTGGCGAAAGACAAGCCAAAGAAACAACCAAAAGACGTGAAGATAACAGATTTACTTGAGACCATAACCGAACAAGTTGCTCAAAGTTTGAACAATCCAGAAGCTCCAAAAGAGCCACTTGAACTCCTTCAACCACCACCACCAGTTTCCGATGAGGAAGCTTTGAGTTTACTCAACTTAAATACAACTGATTCCTTAGGAGAATCCATTCAAATCGATCCAGTAATTCTACTTCAACAATTACAAgccaataatattttagtaaatgaTGGTGCGGATAACGATATGATGCCTCCAAGTTTGCTGCAGTTGGACGATGTCGCCCTGTTGAATTTCAAGTCGGTGGATGGTTTGATGGAAATAAAGAACGATTTGTTGGAGGTGCCAGAGCCGAAGGAAAAACCCAAAGAGTTCCAATGTGACGTTTGTTTTAAGCAGTATTCCTCGAAGGGTGTTTTGAGGCGACACAAGAAAATTCACGAGAGGCAGCGGCAGTATTCCTGCGATACGTGTATTAAAGGTTTTAATAAACCTGAGGAATTGGAGAAGCATTTGTTGGTGCATTCGGGGATTCGACCGTATTCTTGTATGTTTTGTAATAACGCGTTTGCGGAGGAGCAAAGTTTGAAGACTCATATGAAAAGGATACATAATGTGGATGGCGAGGGGACTCTAGTTGTATTTTAA
Protein Sequence: MDSDQLQAILTIPDDTFNLNTELNETVTAYFKDSSIEGATENKQIFYITSNNQFPLTQMSNLIHVPRQQIYLKPPSKLQEEIQPSPVMTPYKCIKCNKEFDTIALYKKHMLWHRNTKKYPCSKCSQGYNNERNLIIHMATHPEGKPTCPVCNLSFQRLASLKSHLMLHQVDEGFVCEECKAEFDKEDELIKHMELHIKLNEEPPNLICPYCKVSHENPIEYKKHISQHVKLRKMVLKGKRFKKKPASKMQNKHVCVICSKSFIKASLLERHLRIHTGEKPFVCRVCNRGFTQNGTLRIHMKTHIDSRPYHCTLCPARFTQKGNLKVHIDKTHTAASIGSKIYKCTLCMCIFKKVGSLNTHMSRFHSENIGMVMDKLKELEEQLNPSKPKKDVLEKPPPALGDTQKEEQDEVVDSGLVRLTESGQDGTIKRHLVKRERVGVVWWYCCSYCSKKCKKPSDLIRHFRVHTKEKPFQCQDCGVTFTLKSTLVSHMKTHAALKEYKCGKCEAVFTCVRSLSLHLSKHEKMYTTNYQCNICNKMYGSLEEVSLHRVSDHLDDSKPLENLVKVVLKRPVHEPQPGVINPAKPRNSLINLPIKANNADTPRPFQCTICDARFTRQINLKRHVKVHENDRQYKCDMCPRAFISSYRLTEHLKYHNNIRKFECQICQKKFVTSTLLKRHVSSHSSKRPYTCPYCSKKFKSLMLTKTHIRRVHKLQITQTLAEDKDENPDSCEALSTDLDKTTGDTSLISPENTTVKISIGTTDSPSDSSNVVVGLSEQFFQIPQNTLQILNQNVEEQNQPQPDPQVFQTIYVNYDDLQLTDSELCNNVLGQIKLHNADSLLLNAALEDTTVIFNIDATKLQQELELSNDTFNAAKQIYDENNMADIVARISSNKTQDSLPLPDLSLSSIQNAVEGGLCLNGDLLATTDTTPQSFYFSPDTLNMNPGEQTLDETDLICINCNQVFNSIKVFKAHECGKKLLDEPLPPEEEKESPPVEKKKPVFECHLCKLTFPNRNWYKRHLESHAKDGSMNTCSYCKKEFKKPSDLKRHLRTHTGEKPYACKKCDKKFALKSTLDSHTRTHDSTNKYVNCDVCNAVFTAKSSLKVHMFIHEKKKPYICNFCPSSFRTAAHRRVHERSQHVAKDKPKKQPKDVKITDLLETITEQVAQSLNNPEAPKEPLELLQPPPPVSDEEALSLLNLNTTDSLGESIQIDPVILLQQLQANNILVNDGADNDMMPPSLLQLDDVALLNFKSVDGLMEIKNDLLEVPEPKEKPKEFQCDVCFKQYSSKGVLRRHKKIHERQRQYSCDTCIKGFNKPEELEKHLLVHSGIRPYSCMFCNNAFAEEQSLKTHMKRIHNVDGEGTLVVF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -