Basic Information

Gene Symbol
ZNF131
Assembly
GCA_963082625.1
Location
OY720262.1:5413153-5426740[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.18 19 7.1 3.5 1 23 489 512 489 512 0.97
2 10 0.0014 0.15 13.7 0.4 1 23 519 541 519 541 0.97
3 10 2 2.2e+02 3.8 0.1 1 16 545 560 545 565 0.75
4 10 0.0013 0.13 13.8 0.6 1 23 573 596 573 596 0.97
5 10 0.0073 0.78 11.4 1.6 2 23 601 623 600 623 0.96
6 10 0.02 2.1 10.1 0.1 3 21 658 676 657 681 0.92
7 10 0.014 1.5 10.6 0.1 1 23 690 713 690 713 0.94
8 10 0.1 11 7.8 4.8 1 23 719 742 719 742 0.94
9 10 3.6e-06 0.00038 21.9 3.3 2 23 752 773 751 773 0.97
10 10 0.00032 0.034 15.7 0.2 1 23 779 802 779 802 0.96

Sequence Information

Coding Sequence
ATGGGAGAACTACCATCAGCTCGTTGTAACCCAACTCGTCCATTTTATCATACTGGAGTGGACCTGACAGGTTTCATCGATGTAAAGGCTAACGTAGGTCGAGGCATAAAAACCATGAAAGGTTATGTAACAGTCTTCGTTTGCATGGCCACGAAGGCCATTCACTTGGAGCTGGTGTCTGATCTAAGTTCAACAGCATTCTTATCAGCACTACGACGAATGGCAGCCCGGCGaggtaccccacggcacatctACAGCGACAACGGAACCAATTTCGTCGGAGCCAACAAACGTCTAGAGCAGGAAACTATCAACCTAAAAAGCACACTAGATCATGAGTTTTACTCAACAGTGGCCGAAATGCAGATAAAATGGCATTTCAATGCTCCTTCCTGGCCCAGTGCTGGGGGGCTATGGGAGAGTGCAGTTAAAAGCCTCAAACATCATTTTCGTAGAGTGATTGGAGACCAAAAGCTCACCTACGAAGAGCTATCAACACTTCTTGCGCAGATTGAAGGTTGCCTAAACACTAGGCCCTTATGCGCACTTAGAGAAGATCCAGATGACATAAATTGTCTAACACCATCTCACTTTTTGTCAAGCGGCCCAGTTCTTACTATTGTGGAAACTGAAACAGATCAACGCACCAGATGGCAATTAGTACAGAAAACTTTCAAAGATATCTGGAAAAGGTGGCAATCAGAGTATTTATGTCAATTATCAAACAGAAGCAAATGGCAGCAAGCAGAAGCAAACATGGAGCTAAATGACATCGTAATCATTCACGATGCGAATGTACCCGCCGGAAAATGGGCTATCGGAAGAGTGGTAGAGCTTCACCCCGGAAAAGACGGATATGTTCGCGTAGTCACGCTAAAAACTAAGAACGGAGCAGGCCTACTAGCACTCGCGCTGTTCGCCTGGCGGCGAGGGCGACTCCGCTGCTCTGCGCGAATCTCgcccccgcccgcgcccgcccccgcgccggCGCCCCGCAGCGAGCGCCCCAACATTCGTGTTCACTACACGACGACTCCGGCGCCGACGGCAACAGTAACAGGTGAAGAGTGTGTTTGTTGGGAATGCTCAGCATTACTCAAGAAAATGCTTAGATTCCAACAGCGAGCAATAAGTGCACAGGAGATTTTGAATAGTACTAGCTTAGTTCCTATTAATTCAAAGAAAGAACTGTTGAATTCAGATTTGCTAACGGAACAAATTGAaaagaaaatttctaaactGACTGGCCAAAAagaaaggaaaacaaaaacgaaaactgcaacaaaacagaatacagatTTGAAAAAAGAACAGCAAATTAAAAAGAAGACATTTAAAATGGCTGGTAAGAATGAAGACAAAATGGCTGCCTCTAACTACACTCTGCTTAGGATGAGTGAAGAGGAAATGCAAGCTAAAAGAGAGACAGACAAAGATGCtgatagatataaaaataaagtaaagtataGATGTGAAATGTGCATCGTTGGATTTTATCATGAACATCTATATGAGAAACATATGAGACTGAGGCATGCAGagTTTGTAGGCGCTTACATATGCAGCGTATGTTCAACCCGCTTCGCCAACACCAGCTCGTACCGCGAGCACGTGGCCAGCCACTACCGCAAATACCGCTGTAAGCAGTGCGGCTATATAGGTTATAAACTATATGAGATGGTGGTTCACGATGCGAGAAAACATGGCGTGAAGCGGTTCAAGTGTTGGCAGTGCCAGGAAGGATTTCCTCTCAAATCCACTCTTCGCATTCACCGCGAGATGAAACACCTGCCGCCGGTCAAGTGTGAGTCGTGCGGGAAACTCTGCAAGACTACGAACGGTCTGACGATACATATGAAACAAGTGCATAGCGGCGCGCCGAAGCAGCGCTGCGCAGTGTGCGGTAAGCAGGTCCGCGACATGAGGGCGCACGTCGCGCGCGCGCACGGCGCCGCGCCCGAGCCCGCCTACTGCGTCGAGTGCGACAAGCGGTTCGTCTCCGCCGAGACGTACAGCATGCACGTCAAGTACGCCGCGCCGCATCGCCACTCCGACACCGTGCTACGACACGCGTGTGAGGAGTGCGGGGCGCGGTTCCTGAGCGCAGCCGCCTTGAAGAAACACGCGATGGTGCGACACACCGACATACGCCCGCATAAGTGCGACCGATGCCACAAGgGCTTCGCCGAGAAACGTTATTTAGACATGCACATTGCTCACAATCACGAGGGCGTGCAGCGCGTCAAGGACAAAGTGTGCCATATATGTGGCAAGGGGTTCACGAAAAAGCATACACTAGTGAACCACATCCGAGTGCATACAGGCGAGAAACCGTTCCGTTGTACGCTCTGCGCCGCCGCTTTCAGCCAGGAGAGTTCGCTCACGACGCACACCCGCGGCGTGCACCTGAAGATAAGACCGCGACCCGGCACTAGGACTAATCACTGA
Protein Sequence
MGELPSARCNPTRPFYHTGVDLTGFIDVKANVGRGIKTMKGYVTVFVCMATKAIHLELVSDLSSTAFLSALRRMAARRGTPRHIYSDNGTNFVGANKRLEQETINLKSTLDHEFYSTVAEMQIKWHFNAPSWPSAGGLWESAVKSLKHHFRRVIGDQKLTYEELSTLLAQIEGCLNTRPLCALREDPDDINCLTPSHFLSSGPVLTIVETETDQRTRWQLVQKTFKDIWKRWQSEYLCQLSNRSKWQQAEANMELNDIVIIHDANVPAGKWAIGRVVELHPGKDGYVRVVTLKTKNGAGLLALALFAWRRGRLRCSARISPPPAPAPAPAPRSERPNIRVHYTTTPAPTATVTGEECVCWECSALLKKMLRFQQRAISAQEILNSTSLVPINSKKELLNSDLLTEQIEKKISKLTGQKERKTKTKTATKQNTDLKKEQQIKKKTFKMAGKNEDKMAASNYTLLRMSEEEMQAKRETDKDADRYKNKVKYRCEMCIVGFYHEHLYEKHMRLRHAEFVGAYICSVCSTRFANTSSYREHVASHYRKYRCKQCGYIGYKLYEMVVHDARKHGVKRFKCWQCQEGFPLKSTLRIHREMKHLPPVKCESCGKLCKTTNGLTIHMKQVHSGAPKQRCAVCGKQVRDMRAHVARAHGAAPEPAYCVECDKRFVSAETYSMHVKYAAPHRHSDTVLRHACEECGARFLSAAALKKHAMVRHTDIRPHKCDRCHKGFAEKRYLDMHIAHNHEGVQRVKDKVCHICGKGFTKKHTLVNHIRVHTGEKPFRCTLCAAAFSQESSLTTHTRGVHLKIRPRPGTRTNH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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