Paeg002288.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pararge aegeria
Gene Symbol
-
Assembly
GCA_905163445.1
Location
NC:4176208-4188556[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.9 37 4.6 0.3 2 23 160 182 159 182 0.95
2 10 0.015 0.63 10.2 0.5 1 23 214 237 214 237 0.96
3 10 0.0036 0.15 12.2 2.8 1 23 282 305 282 305 0.97
4 10 2.7e-05 0.0011 18.9 2.5 1 23 309 331 309 331 0.97
5 10 0.35 14 5.9 0.1 2 23 339 359 339 359 0.93
6 10 0.00069 0.028 14.4 0.6 1 21 365 385 365 390 0.93
7 10 8.1e-05 0.0033 17.4 1.1 1 23 398 421 398 421 0.96
8 10 0.0033 0.14 12.3 4.5 1 23 427 450 427 451 0.96
9 10 0.00018 0.0075 16.3 2.1 3 23 463 483 462 483 0.97
10 10 2.8e-05 0.0012 18.8 2.7 2 23 490 512 489 512 0.96

Sequence Information

Coding Sequence
ATGACTGCAGATATTATTGATGAGATAAATGTAATAgacaataaaatagaaattaaacCACTTCTGTTGAAGAaagggaaattaaaaaaagatattaacAAAAGAGTTTCGATTAAcagaaaagttaaaaaacaaTCTACTTATAACAAAGAAGAAGATATCATAAATAAGAAAGCATTAGAAAATAAAGTAGAAATAAAAGCTCTTTTGTTAaagaatagaaaattaaaaaatgatatcAACAAAAGAAAAGTTGATAATCAGGAAAACATGATTTTATTAGAAAATGAAATAGTAATAGAACCGCTATTGATAAATAGAGAACTAAAGAATGATGAAATGAACAGGAGAAAAGTTAAAAACGGAGAAGAATGTGTAAAGGAAGAGGGATTTTCTAGAATAAGAATGACAGAGGAAGAGTTATTGGATAGCATAGAAAAGAGAAAGTTAGAAGAAGGTTATGTTAATGCATCAAACAAATGTAAATCATGTGTTGACGTGTTTAAGGATGAAATTGAATTAGAGGAACACAACAAAAGATTGCATGTACAGAAGCCGAAGTTTATACAATGTGACATATGTCAGGTATACATCAAGTTCTGGTGGCTGCCGGACCACAGATCCGAGCATTTCTTGAAATACCAATGCAACTTTTGCACCAAAGAGTATTACACCGCCATAGATATATTGTTACATTTGAAAAACATACATTCTATGAGGAATGCAATAACACCGGGAATGTTAAAAAAGCTCAAAAGAAAAGCAATGCTGACGAATCCAATTCTGGCGCAAAAAAAGAAAGAACGCAATATTGATAGAACTAGTGAAGAGTCCACCGTGGGGTTCAAATGTTCTGACTGCAATACGTATTttgaGAACAGATATCTCCGTTACAAACATATACTGAAGCTGCACCGGGAGGGTCACAAATGCGCCACATGCGGCAAGTCTTTCGCGTTCAAGAACACTCTGAATAAACACGAGcaGATCCACGGAGAACCTCAGCCCATGGAGCAATGCGCGACTTGCGGTAAAATGGTCAGACGCGACCGCGTAATCGCGCACGCGCGTATACACGCCGCGCGCGCGACCTTCGAGTGCGTCGCGTGCGACAAGCGATTTGTGTCACGCGACTCCTACGAGAAGCACCTCAAGTACGCCAGCAGTCACGCCGTGACCGACGTGCACAAGTACAAATGTACGATGTGCGAGAAGGGCTTCCGTACAATGAGAGAGCTGAACGACCACGTAAACTACAACCACATGGGCAAGACGCTATATAAATGCCCAATATGCCATAAGGCGCTAGCGACGCGCAGGTGTGTGACCCGCCACGTCAGTCGCGCCCACCATGGCATAAAGGAGAAGTCGGGCGACAAAATACTGTGCCAGACCTGTGGGAAGGCTTTCCGGGATAAGAAGTGCCTTCGCGAGCACGAGCTAATACACACAGGCGAGAAGCCGCTGTCGTGCGACATGTGCGGTCGCACGTTCAGACAGAGCGCGTGTTTGTATACGCACAGGCGGCGCGTACACAAGGTGGCGCCAAAGAGGCTACAGGTGCAGCATGCAGAGGCAGTGCGGGACGAACAGACTGAAATACATTGA
Protein Sequence
MTADIIDEINVIDNKIEIKPLLLKKGKLKKDINKRVSINRKVKKQSTYNKEEDIINKKALENKVEIKALLLKNRKLKNDINKRKVDNQENMILLENEIVIEPLLINRELKNDEMNRRKVKNGEECVKEEGFSRIRMTEEELLDSIEKRKLEEGYVNASNKCKSCVDVFKDEIELEEHNKRLHVQKPKFIQCDICQVYIKFWWLPDHRSEHFLKYQCNFCTKEYYTAIDILLHLKNIHSMRNAITPGMLKKLKRKAMLTNPILAQKKKERNIDRTSEESTVGFKCSDCNTYFENRYLRYKHILKLHREGHKCATCGKSFAFKNTLNKHEQIHGEPQPMEQCATCGKMVRRDRVIAHARIHAARATFECVACDKRFVSRDSYEKHLKYASSHAVTDVHKYKCTMCEKGFRTMRELNDHVNYNHMGKTLYKCPICHKALATRRCVTRHVSRAHHGIKEKSGDKILCQTCGKAFRDKKCLREHELIHTGEKPLSCDMCGRTFRQSACLYTHRRRVHKVAPKRLQVQHAEAVRDEQTEIH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-