Basic Information

Insect: Pararge aegeria
Gene Symbol: prg
Assembly: GCA_905163445.1
Location: NC:7440396-7443417[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.28 11 6.3 4.2 1 20 175 194 175 198 0.83

2 10 0.0021 0.087 12.9 0.8 1 23 204 227 204 227 0.96

3 10 3.2e-06 0.00013 21.8 3.6 1 23 233 255 233 255 0.96

4 10 3.7e-07 1.5e-05 24.7 3.0 1 23 261 283 261 283 0.99

5 10 1.7e-05 0.00069 19.5 0.1 1 23 289 311 289 311 0.97

6 10 0.00055 0.022 14.8 0.9 1 23 317 339 317 339 0.96

7 10 0.00015 0.0062 16.5 0.6 2 23 436 458 435 458 0.95

8 10 1.4e-05 0.00056 19.8 2.6 1 23 464 486 464 486 0.97

9 10 7.3e-05 0.003 17.5 2.2 1 23 492 514 492 514 0.98

10 10 0.0014 0.059 13.5 0.0 3 23 523 543 521 543 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.28	11	6.3	4.2	1	20	175	194	175	198	0.83
2	10	0.0021	0.087	12.9	0.8	1	23	204	227	204	227	0.96
3	10	3.2e-06	0.00013	21.8	3.6	1	23	233	255	233	255	0.96
4	10	3.7e-07	1.5e-05	24.7	3.0	1	23	261	283	261	283	0.99
5	10	1.7e-05	0.00069	19.5	0.1	1	23	289	311	289	311	0.97
6	10	0.00055	0.022	14.8	0.9	1	23	317	339	317	339	0.96
7	10	0.00015	0.0062	16.5	0.6	2	23	436	458	435	458	0.95
8	10	1.4e-05	0.00056	19.8	2.6	1	23	464	486	464	486	0.97
9	10	7.3e-05	0.003	17.5	2.2	1	23	492	514	492	514	0.98
10	10	0.0014	0.059	13.5	0.0	3	23	523	543	521	543	0.92

Sequence Information

Coding Sequence: ATGGATGATTCGTTTATTATCGCCAATTTCCACGCGCTCTGTCGACTTTGCCTTAACAAAAGTAGCCTCACTACCTCTATTTTCAATACTTCTGATGATGAGGCTAATATGTCTCTAACCTCGAAAATCGCTGAATGCTTTGAACTACAGGTAGATCCCAATGATGGTCTCCCTGCCAGAATATGctataaatgtttgtttaaacTGAATAAATGTTCGAAATTCAGATCACAGTGCATTCAAAGTGAAGCTCGATTAAGGCAGATAACAAACAGTGTCAATGAGTtggaaaattcaaattcatctGAGCTCAGTGCTTTTAATTATAGTAACATTCAAGAACAAAAACCTAAACCAGAAGACTATATTGTGGAAGATAGCGTTGTTATGGTTGTGGATCCCAGCCTTGATTATGACTCTTCTGAAGAGTCTGAAAATGTGGATCAAACTGAAGTTGAAACAGTTGAAAGAAATAATACACCTGATGGTGAAACAAACTCTGAATCATTTTACAAAAACGTTTTTATGTGCAAGTACTGTGACCAAGCTTTTGTTTCGCAGGAAAAATGTAAAGAACATGAGCATGGTTTCCATGATCCTAACCTACCCTACAAATGTGTTGAATGCAGTTTGGTATTTGCTGAACGAAGCCAGTATGTTGCCCACACTAAGCATGTGCACGGAAGTGACAAACCGTACCATTGTCCAGAGTGTGATAAATGCTTTGGTAGGAGGTCAGATTTACGTAAACATTCAATTGTGCACACAGGTGTAAGACCTTTCCAATGCCAATATTGTTTGAAAAGTTTCTCTCGTAATACTAATTTGAGTAAACATCTGAGAATTCATGCAGGGCATAAGCCCCATGTGTGTCCTCTTTGCCCTCGTAGCTTTGTAGCAAAAGGAGATTTACAGCGTCATGTATTAGTTCATTCTGGAATGAAACCATATTCTTGTCGAAAATGTCCACTTACATTTGGTCGTAGAGACAAGCTTATTAAACATGAAGTTAAACATGGGCATGGTACTGAACATAAAGAATATGAAAATGACCAAGAAACACATGACATGGTAGTTAGTGTAAATCCATTTAATAACCTAATGACTTCACCTACACAACATAACTCAGGCAGCACAAACattaataatgattatgatcTGCCCAGAGTACCAGATCACATTGCTGGTGAGGGAAGCTTCATAAGCCAAATGCAAAAGAATCCATCCACTTCTGGTAAACGAACACAAAATTCTCCATCCAAACAAAAAGTTACAACTCCCATTAAGAACAGACCTAAGAATATTAAATGTCATCAATGCCCTAAAAGATTTGCTTCATTAGATGCTTACAAAACTCATGTCTCTATAGCACATATTGGTTCAAGAGTATTCCAATGTAAAATCTGTTTCAAGAAGTTCTCTAGGAAAAGGGAACTCGATCGACATGTTACAATACACTCTGGTATGAAGCCATTTAGTTGCAGTCAGTGTGATAAAAAGTTTGTCAAAAAGGATAAATTAGACAAACATGAACAGATGCATGAATGTTTGGTTGTAAACATGCCTTGTATAGAATGTGGTGCCACTTTTGAAAAGAAAGCTGACCTAGTGGCGCACATTAAATCCCACTTCACTGATAATTTTGATGATAAAATCCCTGacactgaaattaaaaaagaaaatgagcCAGAGTTTGCTATggatgataatttttatgatgATACCTGA
Protein Sequence: MDDSFIIANFHALCRLCLNKSSLTTSIFNTSDDEANMSLTSKIAECFELQVDPNDGLPARICYKCLFKLNKCSKFRSQCIQSEARLRQITNSVNELENSNSSELSAFNYSNIQEQKPKPEDYIVEDSVVMVVDPSLDYDSSEESENVDQTEVETVERNNTPDGETNSESFYKNVFMCKYCDQAFVSQEKCKEHEHGFHDPNLPYKCVECSLVFAERSQYVAHTKHVHGSDKPYHCPECDKCFGRRSDLRKHSIVHTGVRPFQCQYCLKSFSRNTNLSKHLRIHAGHKPHVCPLCPRSFVAKGDLQRHVLVHSGMKPYSCRKCPLTFGRRDKLIKHEVKHGHGTEHKEYENDQETHDMVVSVNPFNNLMTSPTQHNSGSTNINNDYDLPRVPDHIAGEGSFISQMQKNPSTSGKRTQNSPSKQKVTTPIKNRPKNIKCHQCPKRFASLDAYKTHVSIAHIGSRVFQCKICFKKFSRKRELDRHVTIHSGMKPFSCSQCDKKFVKKDKLDKHEQMHECLVVNMPCIECGATFEKKADLVAHIKSHFTDNFDDKIPDTEIKKENEPEFAMDDNFYDDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00353374;
90% Identity: iTF_01021552;
80% Identity: -