Basic Information

Insect: Pararge aegeria
Gene Symbol: ZEB2
Assembly: GCA_905163445.1
Location: NC:1546789-1558529[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 0.0015 0.061 13.4 1.6 2 21 214 233 214 234 0.96

2 27 0.0064 0.26 11.4 1.5 3 23 295 317 294 317 0.91

3 27 0.03 1.2 9.3 2.0 2 21 321 340 320 341 0.93

4 27 0.00012 0.0049 16.8 0.7 2 23 379 401 378 401 0.95

5 27 0.76 31 4.9 0.6 3 23 409 428 408 428 0.85

6 27 0.0021 0.087 12.9 0.9 1 23 434 456 434 456 0.98

7 27 0.0032 0.13 12.4 0.9 1 23 462 485 462 485 0.97

8 27 0.0033 0.13 12.3 0.7 3 23 496 517 495 517 0.98

9 27 0.13 5.4 7.3 5.9 1 23 527 549 527 549 0.98

10 27 0.0015 0.063 13.4 0.1 2 20 685 703 684 705 0.94

11 27 8.3 3.4e+02 1.6 0.0 3 13 711 721 710 723 0.84

12 27 0.13 5.5 7.3 6.0 1 23 736 758 736 758 0.94

13 27 0.00012 0.005 16.8 0.8 2 23 764 785 764 785 0.97

14 27 1.4 58 4.0 5.2 1 20 788 807 788 809 0.92

15 27 7.1e-06 0.00029 20.7 0.3 1 23 823 846 823 846 0.95

16 27 0.44 18 5.6 2.7 1 23 852 874 852 874 0.94

17 27 0.98 40 4.5 0.6 1 23 908 931 908 931 0.88

18 27 5.9 2.4e+02 2.1 0.1 1 13 938 950 938 953 0.86

19 27 2.8e-06 0.00012 22.0 0.6 2 21 1054 1073 1053 1074 0.94

20 27 3.6 1.5e+02 2.8 2.4 3 23 1109 1130 1108 1130 0.96

21 27 4.4e-05 0.0018 18.2 1.5 1 23 1135 1157 1135 1157 0.98

22 27 0.48 20 5.5 1.8 2 20 1161 1179 1161 1181 0.92

23 27 0.00021 0.0088 16.1 2.4 1 23 1207 1230 1207 1230 0.95

24 27 0.00052 0.021 14.9 0.5 1 23 1236 1258 1236 1258 0.95

25 27 0.11 4.7 7.5 0.1 1 23 1264 1286 1264 1286 0.97

26 27 0.0016 0.066 13.3 0.4 1 23 1292 1315 1292 1315 0.94

27 27 0.00032 0.013 15.5 2.4 1 23 1321 1344 1321 1344 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	0.0015	0.061	13.4	1.6	2	21	214	233	214	234	0.96
2	27	0.0064	0.26	11.4	1.5	3	23	295	317	294	317	0.91
3	27	0.03	1.2	9.3	2.0	2	21	321	340	320	341	0.93
4	27	0.00012	0.0049	16.8	0.7	2	23	379	401	378	401	0.95
5	27	0.76	31	4.9	0.6	3	23	409	428	408	428	0.85
6	27	0.0021	0.087	12.9	0.9	1	23	434	456	434	456	0.98
7	27	0.0032	0.13	12.4	0.9	1	23	462	485	462	485	0.97
8	27	0.0033	0.13	12.3	0.7	3	23	496	517	495	517	0.98
9	27	0.13	5.4	7.3	5.9	1	23	527	549	527	549	0.98
10	27	0.0015	0.063	13.4	0.1	2	20	685	703	684	705	0.94
11	27	8.3	3.4e+02	1.6	0.0	3	13	711	721	710	723	0.84
12	27	0.13	5.5	7.3	6.0	1	23	736	758	736	758	0.94
13	27	0.00012	0.005	16.8	0.8	2	23	764	785	764	785	0.97
14	27	1.4	58	4.0	5.2	1	20	788	807	788	809	0.92
15	27	7.1e-06	0.00029	20.7	0.3	1	23	823	846	823	846	0.95
16	27	0.44	18	5.6	2.7	1	23	852	874	852	874	0.94
17	27	0.98	40	4.5	0.6	1	23	908	931	908	931	0.88
18	27	5.9	2.4e+02	2.1	0.1	1	13	938	950	938	953	0.86
19	27	2.8e-06	0.00012	22.0	0.6	2	21	1054	1073	1053	1074	0.94
20	27	3.6	1.5e+02	2.8	2.4	3	23	1109	1130	1108	1130	0.96
21	27	4.4e-05	0.0018	18.2	1.5	1	23	1135	1157	1135	1157	0.98
22	27	0.48	20	5.5	1.8	2	20	1161	1179	1161	1181	0.92
23	27	0.00021	0.0088	16.1	2.4	1	23	1207	1230	1207	1230	0.95
24	27	0.00052	0.021	14.9	0.5	1	23	1236	1258	1236	1258	0.95
25	27	0.11	4.7	7.5	0.1	1	23	1264	1286	1264	1286	0.97
26	27	0.0016	0.066	13.3	0.4	1	23	1292	1315	1292	1315	0.94
27	27	0.00032	0.013	15.5	2.4	1	23	1321	1344	1321	1344	0.97

Sequence Information

Coding Sequence: atgagTAGACAAGTTGATGTGAAGGCGCTTGTATCCCACGTAATTCGTGGAGACGGGGTTAACAAGTGCCGAATATGTATGGGCGATACTTCGGAGGGACAAGTATACTTAAGTGATACTGTATTAATGGAAGGAGACAAGCCTGTTACATTATCTGAACTGCTGGAAGTCGTCACGGGAATCCAGGTACCGCTGGAGGGTGACCTGCCAGCCGGATTGTGCATGGAATGCTTCACCTGCGCTGTGAACGCCGCTAACTTCAGGTCAATGTGCAGACAGATGTCCAGAAAATGGGACGTGATTCTGCAACTTTTATACGACCTACCATCACAGGACactgaaaaaaagaaaacaattatcGCTATGATTGAcgataataataagataataacTCTAAACGATAAAGATGAGCTAAAATTGGATAAAGTTTCCGAGAGATTGACGAAACATCTAAAGCAATTAGAAAAAGATAGAAAACTGCAAGAGGATATATCCAAAAACAATTGTGATTGGAATGTAGCAGTCAAAGATCAATGTCACGCcattgatgatgattttaactTAGACACACCAACCGGACAGTTGAAGAAACATTTGACGGCACAATTGGACACAAAAACAGCAAGTGCCAAAGTGGCACAGTGTCCAAATTGCGATAAAACGTTTCAACACCCATTAAAACTGTATCACCATATGAAGGGGTCGATAGATATGAAACGAGCGTGTCATATATGCAGTGAGATAATGTCACGCGATGAACTAGTCTCCCATATTGTTGATGTGCACAATATAAAGGTGTACGATTGCAAGAAGTGCCCCGCATTGCTGCTAACAAATAATGCATATAACAAGCATACAACGAAAGCCCATTCACGCGGCGCCTGTACATGTATAGATTGTGGACAATCTTTCCAAACATCCCATGCATTTTATGCTCACATATCTGTACACAGACAAAAAACTTGCCCTAGCTGCGATAAGATATTCCGTAACCAGACCTGCTATATGTATCACGTTAAAAACTGCTGCGATGTAGatgaaacaaacacaaatatGAGGGTAGATGCTGAAAATAAGAGTACTAAAATATTCATTGGTGTAGGCGCACGCGGTAGCACCGACGGGGGGGAGTGCGTATGCGACTATTGTGGTAAAAAGTTTGCCAAAAAGAAGTACGTGGCAGCACATATACAAATAGTGCATATGAAAAACACACACCGTCCGTGCGCGTACTGCGGCAAGTCCCTCGCGACTGCTCATATGACGGAGCATTTAAAGAAACACGAAATCGATCTGTCCTTCACGTGCGAACATTGCGGTATAGTTCTCAAAACTAAGCTTGGTTTTGTCCAGCATTTGAGATTGCATACTGGGGAACGGCCTTACGCTTGTAAAATCTGTAAGGAGACCTTCAGCGCGTCGTCCAGACGATCGGAACACATGCGGAAGGTACATAAAGAGCCATGTCATGTCTTAAAACATGGCTGTAAACTCTGTCCAGCCAAATTCCGCCTACCGTACAGGTTGAAAAAGCACATGAACTCTtcgcatacaaataaaaacgaCGAGACATTGCAGTTTGAGTGCAGCGAGTGCCACGTTAAGTTTGGATCGTGTCGCGGTTTATTACATCATAGCAGGATGCACCAACGAATCCCTTTTCCACATAAGAAACCGGAAAAATCTATCATGTTCAAAGTGTTTAATGAGGTCTTGCTGGAGACTGAACTGCCCGGGGGTCTGTGCAGCGACTGCACCAACAGTGCGTTAAACGTGTGGCACTTCAAAGCGTTATGCAGCAGTTCTGATAAAAAATGGAGAGTTGCaacaacaattttaaataaaaacataggcTCTCTGACACCGTGTGCTGAAGACAAAATGTTTTACATAAGTTTCAATAAGGAAGGCGTTGTCTTCTCAGGCGGCGGAGCCAAAACTGACAATTTAGCAGAAACTGCCGACCGACTTAACAACATTATAAGGTCAGATAGAAAACGGGAACgcaagaaacaaaaaaacccTAACCAGTCGAAATTTCTCTATCAAAACAAATGCTATATTTGCGGAAAAGTGTTTTCTCTCCCCCAATATTTGAGCCAGCATTTGGCTAACATGGCCAAAGGCGCTTGCACTGTGTGCGGTAAGATTGTACCAAGGCAAGGGTTGCCCAAACATTTGGGAAACGTTCACGGGAAATTCGTGCATCACTGCAAAGTTTGTCACCAATATTTCGAAGACCAATCTAGTTTGGACAATCATAAGGAACTGCACAAATTCAATCTGCCACAATGCAGCATTTGCAAGTATGGTTTCAGGAGCGAGAGATCCTTACGCGCTCACATGTACTCCCATACTTTATTCAACTGCACCAACTGTAATAAAGGATTCGAGAATCGCAAATGCTTTGTGTACCACAAAGAACATTGCACAGTAGCGAAACAATACAACGAAGTTGAAGGGATCTATGAATGCGATATCTGCGGCAAGACGTACACTAAAAAACCATCACTAAGAATCCACATAATACAGAAGCATTTAAACGTACTGCCTTACATATGTATGATATGTGGAAAGCGCAGTGCCACTAAGAACCACCATAAGTCACATGAACTGATTCATACCAAGGAGCGCAAGATATACCAGTGTTATTGCGGCGCTAAGTTGAGGTCATCCCTCGGTTATCACATGCACCAAAGGATACATTCCGGGGAAAAACCCTACAAGTGCGACGACTGTGGTGATAGGTTCCTCTCAGCTTCAAGAAGGCTGGACCACATAAAAAGGAGGCACAAGATTGGTGGAGCGGTTCACAAGTGCGAAAAATGTGCCGTCAGCTTCATAAGAGAAGAGCAAATAATTCCTCAGCTGCTGTGCATATCTTGTACCCACGTCGCGACTATGGCATACGAATTCCGCCTGTTCGCGAGAAATTCCCAAAAACTATGGAACAATTGCGTCAATTCCGTAGAAAGCATGCTCCCCTTAAATACCCACCACTCGTTCTACGCTATGATTAAGGAGAATTTGCTTCTCCAAAGTGTCAACAATTTTGAGGGTAGTCCGAAAGATTTGGCGCACCACTTGTCTAATCGCTTCAAAAAGAAGCCGCTTATCGTAGAAAGGAAACCGAGACTACCTCGGGCAGGGCCGTCCTGCGAATGTGAAGACTGTGGAAAGACATTTTCAAGCCCCTATTACCTTAATATACATTTACGTAATAGTGGTCAGAAAGAAGCATGTTGGCTGTGCGGTGTAATGGTGGTACGTGGGCAAGAAATGAGGGACCACTTATCCGATATCCACAAAACGGAAATGTTATTATGTCCAGAATGCCCAATGCTATTCAAAAGTGAATTAGACAGAAGGAAGCATTCAAAAAAGTGTCACGGACCCGGGAAATTCACTTGTAACGACTGCGGCAGGACTTTCCAAAGGAGCAATTCATTCGAGGTGCATTCCCAAATGCATAACGTTAGAACTTGTAGAAGATGCGGAGTGCAATTCACAAATAGAGGGTGCTATAGGGAACACAGGGCGAAATGTGAACCCAACGCAAAACCTGATTTAAAAACTATACCAAGAAGTCGCCGCTCGAACATTCGAGATCCGGCCACTTTTACATGCGATTATTGCAAAAAAACCTATCACTCGCGACCACAGTTGAAAAATCATATACTATGGATCCATATGGATATAAGACCTCATCAGTGTCAATGGTGCGGAAAGAGGTTTTATACTCCAGCGCGATTGGCTGAACACACGGTCGTGCATACGCGTGTTCGAAATTTCGAATGTGATATTTGTGGCGCGAAATTGGTTTCCAAAATGGCCGCCGTATACCATAGACGCAGGCACACGGGTGAGAAGCCATACGAGTGTCCGGACTGCGGGGAGAAATTCATTTCTTCATCGCGCAGGTCCGAGCATGCGAAACGTAGGCACAATAAAGGCTCAAGGTTTCAGTGTACGCTATGTCTGTCTAGCTTTGTTAGGAGTCACGAGTTGAAAAAGCATATGGAAAAAGCGCACAATCCCGAAAGTCAGGCAACGGCTAAAATTAAGAAAGTTAAGGAGTGTTTCCAGTCTACTGCGTGA
Protein Sequence: MSRQVDVKALVSHVIRGDGVNKCRICMGDTSEGQVYLSDTVLMEGDKPVTLSELLEVVTGIQVPLEGDLPAGLCMECFTCAVNAANFRSMCRQMSRKWDVILQLLYDLPSQDTEKKKTIIAMIDDNNKIITLNDKDELKLDKVSERLTKHLKQLEKDRKLQEDISKNNCDWNVAVKDQCHAIDDDFNLDTPTGQLKKHLTAQLDTKTASAKVAQCPNCDKTFQHPLKLYHHMKGSIDMKRACHICSEIMSRDELVSHIVDVHNIKVYDCKKCPALLLTNNAYNKHTTKAHSRGACTCIDCGQSFQTSHAFYAHISVHRQKTCPSCDKIFRNQTCYMYHVKNCCDVDETNTNMRVDAENKSTKIFIGVGARGSTDGGECVCDYCGKKFAKKKYVAAHIQIVHMKNTHRPCAYCGKSLATAHMTEHLKKHEIDLSFTCEHCGIVLKTKLGFVQHLRLHTGERPYACKICKETFSASSRRSEHMRKVHKEPCHVLKHGCKLCPAKFRLPYRLKKHMNSSHTNKNDETLQFECSECHVKFGSCRGLLHHSRMHQRIPFPHKKPEKSIMFKVFNEVLLETELPGGLCSDCTNSALNVWHFKALCSSSDKKWRVATTILNKNIGSLTPCAEDKMFYISFNKEGVVFSGGGAKTDNLAETADRLNNIIRSDRKRERKKQKNPNQSKFLYQNKCYICGKVFSLPQYLSQHLANMAKGACTVCGKIVPRQGLPKHLGNVHGKFVHHCKVCHQYFEDQSSLDNHKELHKFNLPQCSICKYGFRSERSLRAHMYSHTLFNCTNCNKGFENRKCFVYHKEHCTVAKQYNEVEGIYECDICGKTYTKKPSLRIHIIQKHLNVLPYICMICGKRSATKNHHKSHELIHTKERKIYQCYCGAKLRSSLGYHMHQRIHSGEKPYKCDDCGDRFLSASRRLDHIKRRHKIGGAVHKCEKCAVSFIREEQIIPQLLCISCTHVATMAYEFRLFARNSQKLWNNCVNSVESMLPLNTHHSFYAMIKENLLLQSVNNFEGSPKDLAHHLSNRFKKKPLIVERKPRLPRAGPSCECEDCGKTFSSPYYLNIHLRNSGQKEACWLCGVMVVRGQEMRDHLSDIHKTEMLLCPECPMLFKSELDRRKHSKKCHGPGKFTCNDCGRTFQRSNSFEVHSQMHNVRTCRRCGVQFTNRGCYREHRAKCEPNAKPDLKTIPRSRRSNIRDPATFTCDYCKKTYHSRPQLKNHILWIHMDIRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICGAKLVSKMAAVYHRRRHTGEKPYECPDCGEKFISSSRRSEHAKRRHNKGSRFQCTLCLSSFVRSHELKKHMEKAHNPESQATAKIKKVKECFQSTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -