Paeg002157.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pararge aegeria
Gene Symbol
-
Assembly
GCA_905163445.1
Location
NC:258363-279283[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.0011 0.044 13.8 5.0 2 23 359 380 358 380 0.97
2 17 0.00016 0.0064 16.5 2.6 1 23 386 408 386 408 0.98
3 17 0.00089 0.036 14.1 3.6 2 23 416 437 415 437 0.96
4 17 0.0069 0.28 11.3 2.6 1 22 443 464 443 464 0.95
5 17 0.00012 0.005 16.8 6.0 2 23 488 509 487 509 0.97
6 17 0.0011 0.046 13.8 3.7 1 23 561 583 561 583 0.98
7 17 0.00018 0.0073 16.3 0.8 2 23 589 610 588 610 0.97
8 17 2.2e-05 0.0009 19.2 0.6 1 23 616 638 616 638 0.98
9 17 0.17 6.8 7.0 7.5 1 23 643 665 643 665 0.98
10 17 7e-06 0.00029 20.7 3.7 1 23 671 693 671 693 0.99
11 17 0.00038 0.016 15.3 5.7 1 23 699 721 699 721 0.98
12 17 1.8e-05 0.00073 19.5 4.7 1 23 727 749 727 749 0.98
13 17 0.00011 0.0046 16.9 0.3 1 23 755 777 755 777 0.98
14 17 0.025 1 9.5 1.3 1 23 783 805 783 805 0.93
15 17 1.2e-05 0.00047 20.0 0.5 1 23 811 833 811 833 0.98
16 17 9.7e-06 0.0004 20.3 4.8 1 23 839 861 839 861 0.98
17 17 4.7e-07 1.9e-05 24.4 0.9 1 23 867 889 867 889 0.99

Sequence Information

Coding Sequence
ATGAAAAGTCCCTGTCATTATAGTAAAACAATAAACTGCAACATGGAGGCACTACCCGAGCATTCCACTGACACTTGCCTCATAGTACCCAAGGAGGAAATTTTAGATGACCTGGAGATCACGTTTGAAAAGGAATACCAAGATGACAAATACTACATCATACCCAAAGAGGAGCTGTGCAAAAGCAGTCTGCACTTGAACGGTGAAGATTCCTCGGGATTTAACCACACGCCGATTAAGACAGAACTGACTTTGAGTGATGACGTCGTCCAGCTACGTCGAGATTTCAATGAAAACACAGAAACAGAAAATGAACTTGTATCTACACATAAAACCGTCACAAAGATTAAATGGGAACCAGATACTGATGGCAGTGGTTCTGGAGACTCGGCTCAGACGCTTGATCCTCGATTCTACATAAAAAGAACGGACAACGGCGCAGGCGCGGATAACTCAGATGATGGCACGAgccaatataaaattaaatcagaaaggaaaactcaaaataaaataagatgtcATCGATATAGAGATAAGAGAAAGAGCAATAATGATGCAGCAAATACTTCACCTAAAACAATCTCAGTTGATGAGGAGAACATCAAACGTAGAGAATATGACGCACAAAAAAGTAAACGTTACATAGATAAAAACAGAGCTGCTAATTCAATGAATTTACACACCGGTTACAATAATGATATTGATATAGACACTGGTTCACAACACACATACCATGTACCAATAGTTCCACACGACGATCGAAATAATACCATATTGAAGTTATTATTGTCAGACGGTGGTAGAATAAATAGGGTCGACGATGACGAAGAACCGGATTTCTCTGATGATGACAGCCATAGTGAAGTTGACGAAACCAAAAAAAGAAGAAGCATTCTGAATAAAATTAGATGTAAGCGATATAGagataagaaaaagaaaaaaaaagaagcaacTGTTAGTCTAGCTCGTACATTGTCCGTCGAAGAGGAGCAGGAGAAAATAAAACGACGCAGAGAGTACGATAAACAAAGAAAGCCTCCCCAACTGAAGAAGTGTCCGAACAAGGAGCCCCTCTCGTGCCATTATTGCGGGTTCAAGTGTAAATACAAGAGCGCTATAATACGACACATGAGTACCCACAACGGGGAGCAGCCGTTCGCATGCAAGTATTGCGAGTTCAAATGCAGCGACATCAGCACACTGAGCGCGCATATGCGCACACACACGGGAAATGAGAAGTCTCTCTCTTGCCATGCTTGCGGGTACACGTGTAAATACAAAAGTGCTTTACTAAGACACGCGAGGTCACACACTGGCGAGAAGCCGTACGCTTGCAAGTATTGCGAGTTTAAATGCAGCAACGTCAGCACACTGAACTCGCACCTGCGCAAGCGCTTTGGGCCGCCCCCACTTAAGGAGTGTCCGCCGACCAAGCGGGGAAGAAAAGAGAAGGAGCCTCTCTCTTGCCATGTTTGCGGGTACAAGTGTAAATACAAGAGTTCTTTGTCGAAACACATGAGTACCCACAACGATGAAAAGCCGTTCAAACGCAGCAACGTCAGCACACTGAGCCCGCACATGCGCACGCACACGGACGCTTCGCGGCCGAAAAGAGAAAGTTCGCCCCACCACGTTAGAACTGACAAGCCTCACATGAGCCCTCAATCCGAAAAAAAACCATATTGTTGCGAGGAATGTAACGCTTGTTTCACGCTCAAGAATGACTTGGTCGCTCACAAGCGCTCTCACGTTGTAAAACCCTTGAGTTGTGACCTGTGTCAGGCGAAGTTTAAACAGGAGCGTAGTTTAATTCTTCACATGAGAAAGCACACCGGAGAGAAACCCTACGTCTGCGGCCAATGTCAGGCTAAATTTATTCGAAAAGGCGAACTAACTACTCACATGAGGTTCCACAGTGGAGAAACTTATCAGTGCGAACATTGTCCGAAGAAATTTTTGCATAAACCGAGTCTCATTTGCCACAGGAGAACACACACTGGTGAGAAACCTTATTCGTGTGAACTGTGCCACAAGAAATTTACACAGACAGGTACCTTAAATTCTCACATGCAGACGCACGCTGATGCTAAACTTTATTCCTGCGATCAATGTTTCAAGCAATTTTCAAGACAATCGTGTTTCACTTCTCATGTTATGACCCACACAGGAGAGAAACCCTATTCTTGTACTGTTTGCGGGATGAAATTTAGAAGTAGGCATCATTTAATTTCTCACACGAGGATACATACTGGGGAAAAACCTTACTCTTGTTCGTTATGCGATGCGAAGTTCGCCCAAATGAGTTCTCTGAACGGCCACTTAAGGTCCCACTCTGGCGAGAAACTGTATTCTTGCATCTTGTGTCAGGCTAAACTTGCAAGTAAACACTCTTTAACTGTCCACATGCGGTCCCACACTGGTGAGAAACCCTTCTCGTGTGGCGTATGCGAGGCtgaatttacaaataaacaaagccTAACGAGTCACATGAGGAGTCACACTGACGCCAAACCATTTCCTTGTGATCAGTGCGAGGCTTCGTTTAAACACAAGCATAATTTGACTACGCATTTGAGAACCCATACCGGCGAGAAGCCTTATTCCTGCAAAGTCTGTGATTACAGATTCGCTCAAAGCAGTGCGCTAGTGAGGCACACGAGAACTCATAGgtag
Protein Sequence
MKSPCHYSKTINCNMEALPEHSTDTCLIVPKEEILDDLEITFEKEYQDDKYYIIPKEELCKSSLHLNGEDSSGFNHTPIKTELTLSDDVVQLRRDFNENTETENELVSTHKTVTKIKWEPDTDGSGSGDSAQTLDPRFYIKRTDNGAGADNSDDGTSQYKIKSERKTQNKIRCHRYRDKRKSNNDAANTSPKTISVDEENIKRREYDAQKSKRYIDKNRAANSMNLHTGYNNDIDIDTGSQHTYHVPIVPHDDRNNTILKLLLSDGGRINRVDDDEEPDFSDDDSHSEVDETKKRRSILNKIRCKRYRDKKKKKKEATVSLARTLSVEEEQEKIKRRREYDKQRKPPQLKKCPNKEPLSCHYCGFKCKYKSAIIRHMSTHNGEQPFACKYCEFKCSDISTLSAHMRTHTGNEKSLSCHACGYTCKYKSALLRHARSHTGEKPYACKYCEFKCSNVSTLNSHLRKRFGPPPLKECPPTKRGRKEKEPLSCHVCGYKCKYKSSLSKHMSTHNDEKPFKRSNVSTLSPHMRTHTDASRPKRESSPHHVRTDKPHMSPQSEKKPYCCEECNACFTLKNDLVAHKRSHVVKPLSCDLCQAKFKQERSLILHMRKHTGEKPYVCGQCQAKFIRKGELTTHMRFHSGETYQCEHCPKKFLHKPSLICHRRTHTGEKPYSCELCHKKFTQTGTLNSHMQTHADAKLYSCDQCFKQFSRQSCFTSHVMTHTGEKPYSCTVCGMKFRSRHHLISHTRIHTGEKPYSCSLCDAKFAQMSSLNGHLRSHSGEKLYSCILCQAKLASKHSLTVHMRSHTGEKPFSCGVCEAEFTNKQSLTSHMRSHTDAKPFPCDQCEASFKHKHNLTTHLRTHTGEKPYSCKVCDYRFAQSSALVRHTRTHR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-