Basic Information

Gene Symbol
-
Assembly
GCA_003118335.3
Location
JAOPJP010027462.1:961-2276[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.019 1.6 9.6 0.6 1 23 91 113 91 113 0.97
2 11 4.5e-05 0.0039 17.9 0.3 1 23 121 143 121 143 0.97
3 11 0.0019 0.16 12.8 4.5 1 23 150 172 150 172 0.95
4 11 0.014 1.2 10.0 2.1 1 23 178 200 178 200 0.97
5 11 0.0012 0.1 13.4 7.9 1 23 205 228 205 228 0.96
6 11 0.0022 0.19 12.6 1.5 1 23 232 254 232 254 0.97
7 11 6.5e-06 0.00057 20.5 3.2 1 23 260 283 260 283 0.98
8 11 0.0003 0.026 15.3 0.6 1 23 289 311 289 311 0.98
9 11 0.00012 0.011 16.5 3.1 1 23 317 339 317 339 0.98
10 11 6.5e-05 0.0056 17.4 1.1 1 23 345 368 345 371 0.94
11 11 0.0019 0.16 12.8 1.9 1 22 373 394 373 397 0.90

Sequence Information

Coding Sequence
ATGGAAGAAAACGCCGCAACCTCAATATCTCCAGTGATAAAGAATTACAATTTGAAAGAACTGAAGATTGTATTAGACCGTAACGATTGCCTTATTAATTATTATTTAAAGGGAACAAGTAAACATAGATTAAAAAACAATGGTGGCATAAAAGAAATAGAAAAAAGTAAAACAGTGTCCAAAATGAGAAAAAAAACGCAATTCCCAGACACAAAATCAGATTACGAAATAAATCAACAATCAAAATTGTACAATGAAAAATATTCAGCATTCTCTTGCGACGTATGCGGTGATACCTACCAATCGATGCGAGCATTAATGCAGCATACACGTTTCCACATCAAATCCAATGGAATTGCATTTACATGTGCCATCTGTGATAATCAATTTAAAACTAACGATGAACTGATCAACCATAAATTAATCCACAATTCCGAAGACCATTGCTTTGACTGCAAGAAATGTAAAATAACCTTCACAGACCACTACAATTACATGCAACATAATGCCAAACATGTTGATACAGGTGTTTATAAATGTATTGAATGTTCTTACACATTTAATTTGCGAAAATCATATAAAAACCACATAACAATACACTATTTAAGACATCATAAATGTCATTTATGTAAGGAAATATTCACACAACCGAAAGATCTCCATAGACACAAAAAGAACTACCATTATCCTGGTTATGATTGTGTTGAATGCGGTAAACATGTTCACACTCAGAGAGATCTTGACGAACACATGTATATACACACAAGAGTCAAGGCATTCCAGTGTTTGTATTGCGGCAAGGGATTTTCTAAACACGAAGGTCTACGTTATCATATGAAGAAAATGCATACAAAGTCAATTCCTTACGAATGTACAATTTGTTTACTAGGATTTTATAATTCTAGTCGATTCAAAAGTCATATGATTGTACATGATATAGAGAAGAAATATGAATGCAATGATTGTGGTCGTCAATTCTTCCACAGAGATAGTATGATTCAACATTCAAGGTATCATATGAACTATATGTTGTACAAGTGCCCTATGTGTAAAAAAACATTTGCAACTTACCAAAGACTAAAGTTACATACAGAGGAGGTACATATGAAGACAAGACATAAATGTGATTTGTGTAGTATTTCTTTCATTTCAAAACGGGGCTATCGAAAACATTTAGGTACGGAAAAGCATATCAATCAGGCTGCCGTAGCAAAATTAGGTTTTTTTAATGCTAAGTGA
Protein Sequence
MEENAATSISPVIKNYNLKELKIVLDRNDCLINYYLKGTSKHRLKNNGGIKEIEKSKTVSKMRKKTQFPDTKSDYEINQQSKLYNEKYSAFSCDVCGDTYQSMRALMQHTRFHIKSNGIAFTCAICDNQFKTNDELINHKLIHNSEDHCFDCKKCKITFTDHYNYMQHNAKHVDTGVYKCIECSYTFNLRKSYKNHITIHYLRHHKCHLCKEIFTQPKDLHRHKKNYHYPGYDCVECGKHVHTQRDLDEHMYIHTRVKAFQCLYCGKGFSKHEGLRYHMKKMHTKSIPYECTICLLGFYNSSRFKSHMIVHDIEKKYECNDCGRQFFHRDSMIQHSRYHMNYMLYKCPMCKKTFATYQRLKLHTEEVHMKTRHKCDLCSISFISKRGYRKHLGTEKHINQAAVAKLGFFNAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01147584;
90% Identity
-
80% Identity
-