Pmem002505.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Papilio memnon
Gene Symbol
ZEB2
Assembly
GCA_003118335.3
Location
JAOPJP010000021.1:153293-157363[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.49 43 5.2 0.7 1 23 19 42 19 42 0.96
2 26 1.1e-05 0.00095 19.8 2.2 2 23 48 69 47 69 0.95
3 26 0.042 3.6 8.6 1.5 2 21 73 92 72 93 0.92
4 26 0.0029 0.25 12.2 1.1 2 23 131 153 130 153 0.93
5 26 4.1 3.5e+02 2.3 0.4 2 23 160 180 159 180 0.85
6 26 0.0055 0.48 11.3 0.2 1 23 185 207 185 207 0.98
7 26 0.033 2.9 8.9 0.7 1 23 213 236 213 236 0.96
8 26 0.00025 0.022 15.5 2.0 1 23 245 267 245 267 0.97
9 26 0.015 1.3 10.0 1.6 2 22 386 406 385 406 0.93
10 26 3.8 3.3e+02 2.4 2.4 3 23 412 432 411 432 0.92
11 26 0.0026 0.23 12.4 2.4 1 23 437 460 437 460 0.97
12 26 0.00077 0.067 14.0 0.1 1 23 465 487 465 487 0.94
13 26 0.00014 0.012 16.3 1.1 1 23 523 546 523 546 0.97
14 26 0.15 13 6.8 2.1 1 23 552 574 552 574 0.87
15 26 1.5 1.3e+02 3.7 2.0 5 23 584 602 581 602 0.95
16 26 0.11 9.3 7.3 2.0 1 23 608 631 608 631 0.93
17 26 0.00018 0.016 16.0 0.8 1 21 639 659 639 660 0.95
18 26 5.2e-05 0.0045 17.7 2.0 2 21 769 788 768 789 0.94
19 26 0.001 0.088 13.6 1.5 1 23 822 845 822 845 0.96
20 26 3.7e-05 0.0032 18.2 0.2 2 23 851 872 850 872 0.96
21 26 0.75 65 4.6 1.5 2 20 876 894 876 896 0.91
22 26 0.0011 0.092 13.6 0.2 1 23 922 945 922 945 0.91
23 26 0.0012 0.11 13.4 0.8 1 23 951 973 951 973 0.92
24 26 0.071 6.2 7.8 0.1 1 23 979 1001 979 1001 0.97
25 26 0.043 3.7 8.5 1.0 1 23 1007 1030 1007 1030 0.94
26 26 0.00088 0.076 13.8 0.4 2 23 1037 1059 1036 1059 0.96

Sequence Information

Coding Sequence
ATGAATCGAGATGAGTTAGTGAGACATTTAAAAGAACAGCACAATCAGAAGCCTTATGACTGTAAAAAGTGTCCTGCTTTATTGCCTTCGTATCATCAATATGTTCAGCATTTACGTCAAGCACATTCACAAGGTTCTTGCACTTGTGGTGACTGCGGACGAAGTTTCAAGACCTCCAATAGTTTCAGAGCTCATCTCTCCGTACATACAATTAAGTCTTGTCCGAGCTGTGACGAAGTATTCCGTAACCAAACTTGCTACTTGTACCACGTGAAGAAATGCTGTAATTTAGAAAGTAAAAAAACTCATAAGGGTATGTTAGAAGTGAAGAATAAATGGAGCGAGAAGAAAGTAAAAGTGGGTTTGCGGGGAAGGATCGATAAGGAATGTATCTGTGATTATTGTAATAAGAAGTTCGCGAGCAAGAAGTTTATATCGGCTCACATAGAGATAGTCCACATGAAGAATACGCACAGTCCATGCGTTTACTGCGGGAAGTTCCTCGCCGCGGCTCACATGTCCGAGCACGTGAAGAAGCATCAAGATTTGTCATTCAAATGTGACCTTTGTGGTATTATTTTAAGGACTAAATTAGGTTATATCCAGCATTTACGTCTGCACAGTGGTGAAAAGCCGTACCCATGTATGTATTGTAAGGAATCGTTTTCGGCCTCCTCCAGAAGGTCGGAACACGTAAGGAAAGTACATAAGAGTTCTGATATAGTGTTGAAACATGAATGTAGTAAATGTTCAGCGAAATTCCGACTACCCTACATGCTGAAGAAGCATATGTTAGTTCACAGTGAAAGACAACTTAAGTTTGAATGTTACGTGGAGGAGGCGAAGAGTTTGCCGCGCGGCGTCTGTTCCTCATGCACACAGATGGCGCTCGCGGCGGCACATTTCCGTAATTTTTGCCACGAATCCGCTAACCAATGGACACGAGCCACGTCCATCCTCAATGCTATACCAACACAACTATCTGAAGAGAAAGCTTTCTTCTTAATTTATAATAAAGATGCCATATTTAAAGATAATAACAATATACCGTCCGTAGCAGACGCTGTTAGTCGACTAAATCAAATAACCGAAGAGCCTGTGATCACCAAAGTGGTAACTCAACGACAGAAATCGTTTACGAAAGGGTCTCCCTGGAAATGCCAATGTTGTGGCAAGAAATTTCGATTATTGTACTCATTGAATATTCATCTGAGAATGACTAAGAACAGAGCTTGCACGCATTGTGGTCTAATCGTTACAAAGAAGAGGTTGCATCAGCATTTAGAAAGAGCACACGGTATATTTCTGTTTCATTGTCAAACGTGTCACAAATTATTTAAAGGCGCATCGGAATTGGATCTACATATACAAACAGCACATAGCGTTATATCATACTCGTGTCCAGTTTGCAAGCAAGGTTTTGTAAACGAGAGAGCGCTACGAGCACATAAGTACGCTCACACTTTGTTTAATTGTCTATCGTGTAATAGCAGCTTTGAAAACTTGAGATGCTATAGATACCATATTGGTCACTGCCTGGGGTCCAAAGCACCTCCAGATTCGTTATATGAATGCGATTATTGCGGTTCTAAATACATAAAAAAGGATTCTCTTAAAAGTCACATTCAAAATAAACATTTGAAGGTATTGCAATTCGTATGCCAGAAGTGTGGCAAGAGAAGTACCAGTCTTGCTCATCACAAGGCGCATGAAGTTATCCACAAGACGGAAAGGGAGGTTTTTAAATGCCATTGTGGTGCAAAACTGACGACTCAGCTGGGATTCAACCTGCACCAAAGGATACATTCGGGTGAAAAGCCATACGAGTGCAAAAAATGTGGCGAAAGATTCCTGTCAACGTCCAGACGTCTGGATCACATGAAGAGGCGACATATGAGCACTGAGGACATGCCACATAGATGTAGGGAATGCTCGGCCAGTTTTATAAGACCTTCATTGCTTAAGAAGCACTATAAAGTCATGACAGAAGACGCTTTCTGCCCTCGGGGTATCTGTGTAACTTGTACAGACGCGGGCATCAACGCTTATGAGTTCCGAATGCTAACGAAGAATTCCCACAAAGTGTGGTCAAACTGTGTGAACAATATAGACACGGTTGTCGACAGCGGAAAACCACCCAATTCCTTGTACACGATAATGAGGGAAGACCTATCAGTTCTGACGGTCAACACCTTTAAAGGCGACTCCAAATCTCTCCTGGATCATCTCGTCAATCGTGTTTCTAAAAAGAAACCAGTTGAAGTGGAAAAGAAGCCAAGAGCGGCGCGATCGGGCCCGCCCTGCAAGTGCACTGATTGTGGGAAACAATTTAACAGCCCGTACTATCTTACCTTGCACTTAAAGAACAGTGGCCAGAAAGAAGCTTGTGCTCTGTGCGGTACGATGGTGTTTAGAGGTTTGGAAATGAAGGAACATCTTCAGGCGTCCCACGACAAGTTGGTCCACATGTGTACCGATTGTCCGATGCTGTTCACATACGAATACGAGTTACAGCAACACACGAAACGAGCTCACAGACCGGGCGCTCTGACATGCTTCGACTGTGGAAGAACCTTCCCGAGGAATGCGTCTTTCGAAGTTCACGCACAGATGCATGCGGTGCGGACGTGCAGAGCTTGCGGCGCCCAGTTCACGAACAGAGCGTGCTACCGGCAGCACCGCTCCAATTGTGAGCCCGGAGCGAAACCCGATACTAAAGATGTACCCCGGAGTCGACGCTCTAATATACGGGATCCCGCAACTTTTATATGCGATTATTGCGGCAAGACCTACCTTTCGAGACCTCAACTAAAGAACCATATAGTATGGATACACATGGATATAAGACCGCATCAGTGCCAATGGTGCGGGAAGAGGTTCTATACTCCGACACGTCTCGCGGAGCACAGTGTCGTCCACACGCGGGAAAGGAACTTCGAATGTGACATTTGTGGCGCGAAACTCGTTTCCAAGATGGCGGCGGTGTACCATAGACGAAGGCACACAGGTGAGAAGCCGTACGAGTGTCAGTCTTGTGGGGAGAAGTTTATATCTTCTTCTCGCAGATCTGAGCACGCGAAGCGGCGGCACGGGCTGGGATCTAAACTGCAGTGTATGGACTGTTCCGCCGCGTTTGTGAGAATTCACGAGTTAAAGAAACACATTCTTAAAGTGCACGGTACACATAGTTCTGAGACAACAATAACTACTAGATGTTAG
Protein Sequence
MNRDELVRHLKEQHNQKPYDCKKCPALLPSYHQYVQHLRQAHSQGSCTCGDCGRSFKTSNSFRAHLSVHTIKSCPSCDEVFRNQTCYLYHVKKCCNLESKKTHKGMLEVKNKWSEKKVKVGLRGRIDKECICDYCNKKFASKKFISAHIEIVHMKNTHSPCVYCGKFLAAAHMSEHVKKHQDLSFKCDLCGIILRTKLGYIQHLRLHSGEKPYPCMYCKESFSASSRRSEHVRKVHKSSDIVLKHECSKCSAKFRLPYMLKKHMLVHSERQLKFECYVEEAKSLPRGVCSSCTQMALAAAHFRNFCHESANQWTRATSILNAIPTQLSEEKAFFLIYNKDAIFKDNNNIPSVADAVSRLNQITEEPVITKVVTQRQKSFTKGSPWKCQCCGKKFRLLYSLNIHLRMTKNRACTHCGLIVTKKRLHQHLERAHGIFLFHCQTCHKLFKGASELDLHIQTAHSVISYSCPVCKQGFVNERALRAHKYAHTLFNCLSCNSSFENLRCYRYHIGHCLGSKAPPDSLYECDYCGSKYIKKDSLKSHIQNKHLKVLQFVCQKCGKRSTSLAHHKAHEVIHKTEREVFKCHCGAKLTTQLGFNLHQRIHSGEKPYECKKCGERFLSTSRRLDHMKRRHMSTEDMPHRCRECSASFIRPSLLKKHYKVMTEDAFCPRGICVTCTDAGINAYEFRMLTKNSHKVWSNCVNNIDTVVDSGKPPNSLYTIMREDLSVLTVNTFKGDSKSLLDHLVNRVSKKKPVEVEKKPRAARSGPPCKCTDCGKQFNSPYYLTLHLKNSGQKEACALCGTMVFRGLEMKEHLQASHDKLVHMCTDCPMLFTYEYELQQHTKRAHRPGALTCFDCGRTFPRNASFEVHAQMHAVRTCRACGAQFTNRACYRQHRSNCEPGAKPDTKDVPRSRRSNIRDPATFICDYCGKTYLSRPQLKNHIVWIHMDIRPHQCQWCGKRFYTPTRLAEHSVVHTRERNFECDICGAKLVSKMAAVYHRRRHTGEKPYECQSCGEKFISSSRRSEHAKRRHGLGSKLQCMDCSAAFVRIHELKKHILKVHGTHSSETTITTRC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01139100;
90% Identity
-
80% Identity
-