Basic Information

Insect: Papilio machaon
Gene Symbol: zfh1
Assembly: GCA_001298355.1
Location: NW:859462-869606[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.028 1.5 9.1 0.8 1 23 85 107 85 107 0.94

2 8 2e-05 0.0011 18.9 4.4 1 23 118 140 118 140 0.98

3 8 9.1e-07 4.9e-05 23.2 6.1 1 23 149 171 149 171 0.99

4 8 0.00062 0.033 14.3 1.4 1 20 177 196 177 198 0.94

5 8 0.0018 0.096 12.8 0.3 1 21 454 474 454 475 0.95

6 8 5.9e-06 0.00031 20.6 1.4 1 23 783 805 783 805 0.94

7 8 1.4e-05 0.00073 19.5 7.4 1 23 811 833 811 833 0.98

8 8 0.05 2.7 8.3 7.1 1 21 839 859 839 860 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.028	1.5	9.1	0.8	1	23	85	107	85	107	0.94
2	8	2e-05	0.0011	18.9	4.4	1	23	118	140	118	140	0.98
3	8	9.1e-07	4.9e-05	23.2	6.1	1	23	149	171	149	171	0.99
4	8	0.00062	0.033	14.3	1.4	1	20	177	196	177	198	0.94
5	8	0.0018	0.096	12.8	0.3	1	21	454	474	454	475	0.95
6	8	5.9e-06	0.00031	20.6	1.4	1	23	783	805	783	805	0.94
7	8	1.4e-05	0.00073	19.5	7.4	1	23	811	833	811	833	0.98
8	8	0.05	2.7	8.3	7.1	1	21	839	859	839	860	0.96

Sequence Information

Coding Sequence: ATGAAAGTGCACAGCTCGCTTATGGGAGTGGGCGGCTGGTGCGAGCGCCTGGCGGCCGGCTGGCTGGCCGACATGCGGAGTAAGCAGGTCCCCACCTCGACCACCTCGGCCAGGCTCGCCGCATTCATCCGGCCGCTGGGAGGCGGTGATGTGGGCGCGGGCGTGGGCTCGGGCGTGGGAGCGCGCGGTGGCGCGGAGGGCGAAGAGGAAGAGGAGGAACGCGGGAGCTCGCCACTAGGCCCCGGCGGGCCGCACCGCTGCACGCAGTGCCGTGGCGCCTACCCGTCACGCGCGCAGCTCGAGCGCCACGAGACGCTGCACGCGCCCAGCACTCAGGTGGATACCCTGCAATATACCTGCAAGATCTGCCACAAAAGCTTCCAGAACGTGTACCGGCTGCAGCGGCACATGCTGAGCCACGACGAGAGCGCCCTACTGCGCAAGTACAAGTGCAACGACTGTGACAAGGCGTTCAAGTTCAAGCACCACCTGAAGGAGCACCTCCGCATACATAGCGGAGAGAAACCCTTCGAATGCGCCAACTGCGGCAAGAAGTTCTCCCACTCCGGTTCCTACTCAAGCCACACCACCTCCAAGAAGTGCCTCGTTATGAACCTGAAGATGGGTAGAATCAAACCCAACAACCCGGCGCTCAACCCCAACCGGAGCCCCGCGCGGAAGCGCGCCTCGGCGAGTGCGTTAGTCGCCTCTCACCTCAACAACAACCTGCTGCCCAACGGCGGCTCGTTCCTGCATATGCTGCCAAAGTACAACGACGCGACCGCCTTCTTCGCTTCGATGTCAGCGCAAGAAAACTTTCCGCGCGCGCCCCTCCCCCAGCCGGCGCTCAATCCCTTCTACCTGCCAGGCGGCGTGCCCCTCAGCCCTGCGGCCGGCATTGCGCCCTACAGCTTTCCTTCAACCCTCAGCCAACTGTTCGAGCGAATAGCCTCGACGCAGTACCATCAGAGAAAAATAGAGAATGTTATTGATCCAAAATTAAGCAGTCCTCTCGCGGCGAACCCCGAGGACATGATAGAAGAAATCACAGAGGAAGATGATAAACGATCCGAGGGCAGCGCTGAGCTCGTCATGGATATAGAGGACGAGGAATCGGTAGCTATTAAGAGAGAAAATGAAAGTGCGGAAAATGAATATAGGCCGCGATCCCGCGATTCGATTTGTGactccaaaaatattttagataatagTGAACACGATCTCACAACGTCGCCAAGAATACgaaaaactgaaaatatttttacggaGAGAATGAAGAGCGGATCTCCTGCGGATGGAACGTTCCACGAGCCACCGCTTTCACCCGGGCCTACGGTAAAACATGAGATCGTCGACGACTTCGTATGCTATAAATGTAGTCTGTcttttaaagacaaaaatgACTTAGTAGAGCACGAGAGGTTAGTGTGCGGAAATCTCTTCAGAAAACACGAAGGTCTCGCCGCTCAAGTGGCCGAGACGGTGGCGCTCAACAGACTGGAGGCCGAGCTGCAGGCGAGCACGCGCGGCGCCGGCGCCAGCGACGACGACGACACGACAACGACGCGGGAGGATCGCGACGACAAAATGTCCATACACGATACGGATAGAAAGATCAGAGTGCGAACCGCGTTGAGCGAGGAGCAGCaacaagttttaaaagaatactATGCGGTAAACTCTCGACCCAATCGGGAGGAATTTAAGAAAATCGCTCAGCAAATAGGTCTGGACAACCGAGTGGTTCAGGTGTGGTTCCAGAACAACAGAGCCAGGGTGCGAAGAATGACTCAACCGGTAGCCCACTCCGATCAACCGCTCGACTTGTCGACCAAGAAGTCGAGTCCGTCCCTGGCGTCGAGCCCGAGCCCGTCGTCGCCGGGCAGCGCGCCCGCCACGCCCGGCACGCCCGGCACGCCCGGCACGTGCGCGCTCTCCGACTGCGAGGAGGCGGTCAACCTGAGCCAGAAGTCTTCCCGCAGCACGACGCCCCTGCGCGTGCAGCCAGGCCTCGTCgcgcccgcccccgcccccggcTACCCGCATTCCAACTGCTCCTCCTCCTCCTTCTCAGATTTTATGGTGTCGCCCTCGCCGACAGAAATAGTGCTCGGACACAAACGAATCTACCCCAAGAAGATGTCCGTCAATCCTATTATACCGATGGGCACTCTCCTGCAATACAACGACATGGTGCGAGTCCCCGCGCCGAGCCCGGGCTACGAGCGGCCCGAGCGCGCCGACCGCCCCGCCTGGGACGAGGCGCCGCTGTCGGCCGACTTCGACGACGACGCCGCGTTActcaagaaaaaaatgaaaaccgAACTGAAAGAAGGGGAGGGACAATTCGTGTGCAACCAGTGCGATAAGACCTTCGTCAAGCAAAGTTCTCTGGCGCGGCACAAGTACGAGCACTCAGGTCAGCGGCCGTACAAGTGCGAGGAGTGCCCGAAGGCGTTCAAGCACAAGCACCACCTGACGGAGCACAAGCGGCTGCACACGGGCGAGAAGCCCTTTCAGTGCTGCAAGTGCCTCAAAAAGTTCTCGCACTCCGGCTCCTACAGCCAGCACATGAACCACCGCTTCGCCATCTGCAAGCCCTACAGGGATTAG
Protein Sequence: MKVHSSLMGVGGWCERLAAGWLADMRSKQVPTSTTSARLAAFIRPLGGGDVGAGVGSGVGARGGAEGEEEEEERGSSPLGPGGPHRCTQCRGAYPSRAQLERHETLHAPSTQVDTLQYTCKICHKSFQNVYRLQRHMLSHDESALLRKYKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHTTSKKCLVMNLKMGRIKPNNPALNPNRSPARKRASASALVASHLNNNLLPNGGSFLHMLPKYNDATAFFASMSAQENFPRAPLPQPALNPFYLPGGVPLSPAAGIAPYSFPSTLSQLFERIASTQYHQRKIENVIDPKLSSPLAANPEDMIEEITEEDDKRSEGSAELVMDIEDEESVAIKRENESAENEYRPRSRDSICDSKNILDNSEHDLTTSPRIRKTENIFTERMKSGSPADGTFHEPPLSPGPTVKHEIVDDFVCYKCSLSFKDKNDLVEHERLVCGNLFRKHEGLAAQVAETVALNRLEAELQASTRGAGASDDDDTTTTREDRDDKMSIHDTDRKIRVRTALSEEQQQVLKEYYAVNSRPNREEFKKIAQQIGLDNRVVQVWFQNNRARVRRMTQPVAHSDQPLDLSTKKSSPSLASSPSPSSPGSAPATPGTPGTPGTCALSDCEEAVNLSQKSSRSTTPLRVQPGLVAPAPAPGYPHSNCSSSSFSDFMVSPSPTEIVLGHKRIYPKKMSVNPIIPMGTLLQYNDMVRVPAPSPGYERPERADRPAWDEAPLSADFDDDAALLKKKMKTELKEGEGQFVCNQCDKTFVKQSSLARHKYEHSGQRPYKCEECPKAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01140831;
90% Identity: iTF_01149489;
80% Identity: iTF_01144454;