Basic Information

Gene Symbol
rst2
Assembly
None
Location
scaffold:75678-82936[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.0017 0.1 12.9 0.1 3 23 138 158 136 158 0.97
2 15 0.0019 0.12 12.7 2.9 1 23 266 288 266 288 0.98
3 15 6.8e-05 0.0042 17.3 1.2 1 23 294 317 294 317 0.96
4 15 0.029 1.8 9.0 5.7 1 23 322 345 322 345 0.90
5 15 1.9e-06 0.00012 22.1 0.4 2 23 503 524 502 524 0.98
6 15 0.00014 0.0087 16.3 2.4 1 23 530 552 530 552 0.98
7 15 0.077 4.7 7.7 6.4 1 23 606 628 606 628 0.96
8 15 0.84 51 4.4 1.0 2 23 636 657 635 657 0.95
9 15 0.0095 0.58 10.5 4.3 1 23 663 685 663 685 0.95
10 15 7.9e-07 4.8e-05 23.4 0.6 1 23 691 713 691 713 0.99
11 15 0.0016 0.1 12.9 2.7 1 23 722 744 722 744 0.98
12 15 0.00034 0.021 15.1 2.1 2 23 789 810 788 810 0.97
13 15 0.056 3.4 8.1 6.2 1 23 827 849 827 849 0.95
14 15 1.4e-06 8.5e-05 22.6 0.6 1 23 855 877 855 877 0.98
15 15 4e-07 2.4e-05 24.3 3.1 1 23 883 906 883 906 0.98

Sequence Information

Coding Sequence
ATGAGTATTCAAAGTGGGGCAGAAATAGATCCTCTAGGGACATACGATTTCCCGCCATTTCCAACGTACGCACCAACGCAGCTGTATGCCGGAGTACCGTATCAAAATACCTCATACCACAACTATGACGTTAAAAATGAACCACACCAATACGCCATGGGTTGTATAAATAATTTTAACAGAGAATCAAGTAGTAATACCGAAACAAAACCTGAAACAACCGAAGGAACAAGTAATGTAAACAATATCATTGAAAATCCTAGTAATGCTAAAGAAAATTTTGTAGAGAACCAAAATAGAGAGCAAACAGTACCAAAAAGAAGAATAAAAAAAGAAAGTAATAATGGAACGGAAAAGAAGAACAATTATCTGTCAGAGAAGATAGCTGATAGCAATTTCCCATTCTACGGTTGTGCAGTTTGCAATATTAGTTTCAAATTATTATCCGAATTGGATAAGCACATAGCCACACACAAAGACAGAGTAACGAGCTACGGATTGAGGTTAAAGAATCAAATGAAAAGAAAGAAGCTACGTAAAGAACAGAAGAAGTTGAAGAAATTAAAGAAGACAATAAAAAAGGAGAAGGAGTTTGACATTGAGATTGAAATTAAGCCTGAAGATGGATACATTGGCAATACGAAAGTAGAAGATTATAAACCTGGTCCAGATTTGTTGAATCCTCAAGGCAATGGTGTAGATAATCCGAAATTAGACTCATCGGAGAGTAAAGAAAATTGTAGAAGTAAATCAAAAGATGAAAAGCCTCAAACGGATTACAACTTGGAGAAGATGTTTAAGTGTTTTGCATGTCAGAAGCAATTCACATTGAGCTACTACCTTAAGTTACATGTTAGATCACATACAGATGAGAAGCCCTACACATGTGCGGAGTGCGGGCAGTGTTTCATAACGGCAAGCAAGCTCGGCAGACACAATAAGAGAATACACCTAGCCATAAGGCATCAGTGCAGGATCTGCTATAAATACTTCTCAAGATTTGAATATTTAACAAAGCACTTTGATAACAAACATCCGGAAGACAAGTTGGAAGGCGAGCCTTATGACTATAACGCAATACTTCCCTATTTAAAGGAACTGGAAGATCAGTTACAATTAAAAAAAACTGAACCAGAAAAGAAATCGAACCCAGAAAATCTTTGGGACGATTGGCCTTCAGAAGAGCCTAAAGTATCTAGTAACACGAACTTGACACAAGTAGCTGAAGAGACACTTATAGATGCAAAGGTTGATGGTGAATTGGACGGTGCTGGTATCATAGAAGTGGTGGTTGGAATGCCTGACGAATATCTTGATGCAGAAATTAAGGAAGAAGCTGTCTCCGATGGATCTCTGTCGGATAACATGGATTGTAAAGTTGATAGCATTCAAGAAGATAGCTGTTCTGACAGTGACTACTTCCCATCCAACACCTGGGCGTCATCGCCGAAAATGGATGCTACACCACCGCACAAACCCAAACGTCAGAAAGTTGACCAGCCGATCAAGTGTGAGGTCTGTGAGAAGACGATCAGCTCACAGTCTTACCTCCAGATCCACATGCGAACACATACGGGGGAGAAACCGTTCAAGTGCTACATATGTAATCGTGGGTTCATCACTGCCAGCAAGATGCATCGACATGTGCTGACACATTCGGAGAGTTTAGACGAGCCCGCTATCAAATTGGAGGATAATTCAGATCTGGGATCCGACACTGCCAAGAAGAAAAAGAAACGGAGCAAAGAATGTACAAAGAAAACGAAAATATCGAAACCTAAGAGGATAGAAAAACTTCACAAACAGAAGCGACCCCACGCTTGCGAGTATTGCCATAAACGATTCCTACATCTGGCAACTCTCCAAGTGCATAAAAAGTCTCATGACGGTGAAGAACTGGTCCTGAAGTGTCACTACTGCTTGATGAAGATGGACGATGAGAAGGAATTGAAAGAACATGAAGCTACCCACGAAGGACCGAAGGCTTATCTATGTACATTGTGCGGGAAGACGTACAAAAAACGAGAAACTATGATTTACCACCGGAAGCACCACACAGCAGAGAAGGAGTACACCTGCGACATCTGCTCGAAGAGTTTCCCATCGTCACGCAAACTGGAGAAGCACATCGCGACGCACAGGACGGACCAGTTCGTGGTGCGGTACGAGTGTCCGGTGTGCGCGCACATGTTCAACACCAAGTACCACATCAAGATGCATCTCGTCACACACCAGAAAGAAGGCCTCATAGTGGAAGAGAACAGAAGTGAGATTTTAGCAATGGTGCTTCAGAACGCACGACGGATACCGAAGTACCCTGACGCGCCCGGCATCCACAAACCTTTACCGGACGAGCAGAGTACAAAGTGCAACATCTGTGGCCAAGTGTTCCAGCACTTCTTTTACCTGGAAGAACATTTAAAGAGTCACGGCTCCAAGATAGCTCTGGAAGATGATGAAAAGACAGAAGAGAAGAAGCATATATGTCAAGTTTGCAGCAAAAGTTTCAAACTCCACTATTATTTGAAACTTCACAGTTTCACACATACAAAGGAAAAGCCGTACATCTGCCAGCAATGTGGTAAAGGCTTCATCACCAGAGGGAAACTCAAACGCCATCTGGAGACACATACGGGACTGAAAAAGTACCAATGTCATATTTGTTATAAGTTCTTCACGAGACCAAGTTATTTAAGAATACACGTGAGAACTATACACGGAACTCAAGATAACTTCACGCTTGATAAACGGTTTGGTGTGGGCAGTCTGACGGGATTGGGGCAGGCTGTTTAG
Protein Sequence
MSIQSGAEIDPLGTYDFPPFPTYAPTQLYAGVPYQNTSYHNYDVKNEPHQYAMGCINNFNRESSSNTETKPETTEGTSNVNNIIENPSNAKENFVENQNREQTVPKRRIKKESNNGTEKKNNYLSEKIADSNFPFYGCAVCNISFKLLSELDKHIATHKDRVTSYGLRLKNQMKRKKLRKEQKKLKKLKKTIKKEKEFDIEIEIKPEDGYIGNTKVEDYKPGPDLLNPQGNGVDNPKLDSSESKENCRSKSKDEKPQTDYNLEKMFKCFACQKQFTLSYYLKLHVRSHTDEKPYTCAECGQCFITASKLGRHNKRIHLAIRHQCRICYKYFSRFEYLTKHFDNKHPEDKLEGEPYDYNAILPYLKELEDQLQLKKTEPEKKSNPENLWDDWPSEEPKVSSNTNLTQVAEETLIDAKVDGELDGAGIIEVVVGMPDEYLDAEIKEEAVSDGSLSDNMDCKVDSIQEDSCSDSDYFPSNTWASSPKMDATPPHKPKRQKVDQPIKCEVCEKTISSQSYLQIHMRTHTGEKPFKCYICNRGFITASKMHRHVLTHSESLDEPAIKLEDNSDLGSDTAKKKKKRSKECTKKTKISKPKRIEKLHKQKRPHACEYCHKRFLHLATLQVHKKSHDGEELVLKCHYCLMKMDDEKELKEHEATHEGPKAYLCTLCGKTYKKRETMIYHRKHHTAEKEYTCDICSKSFPSSRKLEKHIATHRTDQFVVRYECPVCAHMFNTKYHIKMHLVTHQKEGLIVEENRSEILAMVLQNARRIPKYPDAPGIHKPLPDEQSTKCNICGQVFQHFFYLEEHLKSHGSKIALEDDEKTEEKKHICQVCSKSFKLHYYLKLHSFTHTKEKPYICQQCGKGFITRGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDNFTLDKRFGVGSLTGLGQAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-