Basic Information

Gene Symbol
-
Assembly
GCA_956483635.1
Location
OY101451.1:98746734-98753914[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.052 5.9 9.0 1.8 1 23 367 390 367 390 0.93
2 11 9.4 1.1e+03 1.9 0.2 2 11 397 406 396 410 0.84
3 11 3.4e-06 0.00039 22.2 2.0 1 23 453 475 453 475 0.99
4 11 0.0025 0.28 13.2 1.2 1 23 483 506 483 506 0.92
5 11 0.00024 0.027 16.4 0.7 2 23 514 536 513 536 0.94
6 11 0.013 1.4 10.9 0.6 1 20 567 586 567 588 0.93
7 11 0.0039 0.44 12.6 5.4 1 23 615 637 615 637 0.98
8 11 0.023 2.6 10.1 1.7 1 23 644 667 644 667 0.97
9 11 1.7e-05 0.002 20.0 2.9 1 23 673 695 673 695 0.97
10 11 1 1.2e+02 4.9 3.9 3 23 702 725 701 725 0.92
11 11 0.015 1.7 10.7 2.5 2 23 729 750 728 750 0.95

Sequence Information

Coding Sequence
ATGGATCAACTGGAAGCATGTCGCATATGTGTAAACTGCTTTTCCTTAAAAGATATggattttatcaatattttccAGCCAAATCAAGAATTTCAACAAGAACTTGATTTTATACAGGGCGAGATACGCCAGTGGCAGTTAAAGATAGAACCAGATGACGGGCTGCCACAAAGAATTTGTGCAAATTGTTTTGCCAAATTCTGCAGTATAGAGGCGTTTCGTAAGGAATGCGAATTGgcacaaaaaaagttaattgaaaCGTTAATGCAACAAAATGCAACCAATGTGCCAGATGTACAGCATGTAATCAAGAACACTGAGGCGCCCTTGCCCTTAGTAGGTAATTATGGGAGCGGTAATATATCATTAGATTCGGGCAATAGTATGTTGGTTTCTTCAGTAAATTTAACTCAAACAGATGTCTCCTTAAGTGATTTCCCAGTATTTGATCAGCAATTTTCACATTACGACAATCCCGCTTTAATCGATGCATCTTCCACTTTATTGGATAATAATTTGATAGCCCCCGAGTCTACACAAGAGTTGGGGTTTTTACCGTCACAAAACTTATATACATTTGAGACTGCTGAACCTCCCTCAACGGGAACACCGCCAATAGATGAGACTGAAACAACGTCCATTATAAATGATATGCTTGTAGAGAAGCGTGGTTATGATGCAATTATAAAACATGATGATCTCGAAGATATGTTACAGCACAGTATTATACCGACTGCAACTAAATTAATACAACAAAGACCGCGACTTACCGTTGGCCAACAGCCGAATGCTGCAAATACTTTAACCATGAAACTGGATCAGAATTTAGGAAAGGAGAAGAGAAATCAGCATAATATTGATTATGCTCTTAAAGTTAAGAGTGAATATCTAAATACAACAACATCGTTTTTAAATCGAGAAGACACCAACTCCGATGTCGAGTGTGATGAGACCGATATGAATGCTCGTTTAAAGCGCTTATCTTATGCTTGCCATTATTGTTTTTGTCCTGAAAGCGGACCCATCGAACATCTTGTCTTCCCCAATGAAGATGCTTTGTCGCAGCATTTTTTCGATGTACATGATCCAAATCGCCCATACACTTGCCCTAAGTGCCCTCAGTCCTGCAAAACTAAATTATTACGAGACAATCATGTCAGACTCATACATAAAATAGTCGAATTTCAAACGTGCAATTATTGTCAGAAACGTTTAAAAGGATCAATAGATGTTCATCAATATAATTGTCAATATGTTGGAGATTGGCAGTGTGAACATTGTAAAGAGAAATTTCTCAATACCGCACTCTATCGTTTTCGCTTACATCAGCGTCAACATGAACGTACTATTAAACAATTCAAATGCCGTACGTGTGACCGTTCTTTTGTAAAGAAAGCCAATTTTGAGGCTCATCAAAGGATGCACAAGGCAGAAGAAAAATCCACTTACACATGCAACATATGCAAGGCCAattttgtcGATGACTATGAACTTAAGCGTCATAAATATCAGCAACACAATATTGATGAAGCTcctataaaatgtaaattttgcaataaagGTTTTGCTTCGAATGTGTTTCTACAGCGGCATATAAGTCAAATTCATCCAGACAATGCAAAAGACAACAATAGCAATAATGCCCAATTATCGGCCACATCATCGTCAACTTCATCTCCCTCGTCGTCATCAGAGCAACATGTTTGTTTGAATtgcaatatgagttttaaaaaactacaaatGTTACAACAGCATTTGCTGTTGGGTCGTGATAAAAATGGTAACTGCTTGTCTACAAGCTGTAACAAACAAGAACGTCGTAGACTTCAGCTTCAGGGCGTATTTCCTTGTTTTCATTGTCCCAGACGTTTTCATTTGAGATCACAACTCGATAAACATTTAAATACACATGATGCTCGCTTACGACCATTTCAATGTGAACAGTGCGTAACACGTTGTCGTTCAACATTCGAATTGCAACAGCATGTGAATGTGGCACATTTAAATATCAAGGCTTTTTCATGCGATGAATGTGGTAAATGTTTTGGTTATAAAAAGGATCTAAGAGATCATATGCTTTTCCATGCAGaaatcaatGTACATTGCACTGAAGAAGGTTGtgaatatatttgtaaaaatgaaAAGGCTTTAAATGATCACATACGCCACAAACACCGTCTACTATCATGTGAATATTGCAAAGAACAATTTACTCGACAAAAATTAACAACTCATTTACGTAAAACTCATCGTAACGAAATCGATAAAGACATAGCTGGCGAATCTGATAACTATTATAAATCTCAATTACTTAATAATAACAATGATATTACACAAATCTCGTTTAATTTACTTAATACTCAACAAACAGATCAGCAATTAGAAAAAACGTCACCACAATTGCCACTCACATCCGTGTCATCTCAAACTTTAGCTGCTGCCATAGAAAATGTTCAACtgcaaacaaaaacattaataacaTCAACATCATTAACAGCTCCTTTAACGCCTTCATCGACTTCATTATTAACAACGTCACCTAACACTTCAATAGttacatcatcatcatcatcattgtcATCATTATCATCTTGTTTAATAAGCAACACAAAaggtaataataataatataagttCTAATTCTATTTCCCCACACAATATGATTGATGATGTTGGTCATCATCATGGACAATTGTGTGAAATGTTTGCCAGTGATTGCCATGATTCAAATGGTACAACGTTAACTTTAAATGGTTTGGTCTCAAATGAACATGATTTGGATTTAGTGGCAAATGATACAAATAATATATTCTTAGTGCCCACAACGTCATCCTCCACAAATGATAACCACTTGGATCAGTATTTTATGGCCTCTTTAATTGATACTGAACAAGAAATAATTGTTACATAg
Protein Sequence
MDQLEACRICVNCFSLKDMDFINIFQPNQEFQQELDFIQGEIRQWQLKIEPDDGLPQRICANCFAKFCSIEAFRKECELAQKKLIETLMQQNATNVPDVQHVIKNTEAPLPLVGNYGSGNISLDSGNSMLVSSVNLTQTDVSLSDFPVFDQQFSHYDNPALIDASSTLLDNNLIAPESTQELGFLPSQNLYTFETAEPPSTGTPPIDETETTSIINDMLVEKRGYDAIIKHDDLEDMLQHSIIPTATKLIQQRPRLTVGQQPNAANTLTMKLDQNLGKEKRNQHNIDYALKVKSEYLNTTTSFLNREDTNSDVECDETDMNARLKRLSYACHYCFCPESGPIEHLVFPNEDALSQHFFDVHDPNRPYTCPKCPQSCKTKLLRDNHVRLIHKIVEFQTCNYCQKRLKGSIDVHQYNCQYVGDWQCEHCKEKFLNTALYRFRLHQRQHERTIKQFKCRTCDRSFVKKANFEAHQRMHKAEEKSTYTCNICKANFVDDYELKRHKYQQHNIDEAPIKCKFCNKGFASNVFLQRHISQIHPDNAKDNNSNNAQLSATSSSTSSPSSSSEQHVCLNCNMSFKKLQMLQQHLLLGRDKNGNCLSTSCNKQERRRLQLQGVFPCFHCPRRFHLRSQLDKHLNTHDARLRPFQCEQCVTRCRSTFELQQHVNVAHLNIKAFSCDECGKCFGYKKDLRDHMLFHAEINVHCTEEGCEYICKNEKALNDHIRHKHRLLSCEYCKEQFTRQKLTTHLRKTHRNEIDKDIAGESDNYYKSQLLNNNNDITQISFNLLNTQQTDQQLEKTSPQLPLTSVSSQTLAAAIENVQLQTKTLITSTSLTAPLTPSSTSLLTTSPNTSIVTSSSSSLSSLSSCLISNTKGNNNNISSNSISPHNMIDDVGHHHGQLCEMFASDCHDSNGTTLTLNGLVSNEHDLDLVANDTNNIFLVPTTSSSTNDNHLDQYFMASLIDTEQEIIVT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-