Basic Information

Gene Symbol
-
Assembly
GCA_956483635.1
Location
OY101451.1:89120779-89129634[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.27 31 6.8 1.8 1 23 395 417 395 417 0.95
2 7 0.001 0.12 14.4 2.0 1 23 423 445 423 445 0.97
3 7 0.00029 0.033 16.1 0.2 1 23 451 473 451 473 0.98
4 7 0.00012 0.014 17.3 1.0 1 23 479 501 479 501 0.98
5 7 0.004 0.45 12.5 2.1 1 23 507 529 507 529 0.97
6 7 0.00014 0.016 17.1 1.0 1 23 535 557 535 557 0.96
7 7 7.8e-05 0.0088 17.9 1.0 1 23 563 585 563 585 0.96

Sequence Information

Coding Sequence
atggcaaCAAAAATGCTACAAGTTCAAGATTATACTGGATATATTAAATGCGGGGAAATCCTTAAATCTCCCTTACCATATAATCAGTATCCTTTCATTCTAAAATGTGTTCAATGCgatgaaataaatttcattttggaatcattTGTAATACACATTCGGGAGCACTACAAAGACGTTGCAGAAGAAAAAGGAAATTGTGATATTAAGAATGCAGATGATTATCCATCGCAAGATGAATGCATtgaaaaatctttaattaaagTGGAAACAATAATAATGGAAGTGGATGATCCCTTAGTTGTTATAAAAAACGAGAAAATTGAAGAATATACGCATGACGATGCTGATGCTGATTATAATACCATAGAAGATAATGAGGACTTCGAAGATAATTCGTGTGATTCTGATGAAGACTTTAATACTGATGATGCCGAAACGGATGACGATGACataAATTACGATTTAAgtaacaagaaaagaaaaaagtctTTTAAAAATACGTTGCCATCAAACATTGAGAACTTCATAAAGTGTAAAGAAAATATGTGCACATTAATAgaactttataaaaatcaaccaaatttatggaaaaaagatTTACCTTTTTATGGTCTCAAAGATAAGCGACAGTCATTTTTAGAAGAAACTACTAAAGAATTGAATGATAAActtaatttggaaataaaatggAAGGAAGTATCAGAtataatttcttatatttaCCGTAAGCAGCGCATAGATTTTAGAAAACTTCGACGTTACGAGGAAGAAAACCAGAACGCAAAAGCGAAGACATATAAGACCTGTTGGTTTTTTGATGATGTAGATTTCCTGCGACCTAAACCAGTAGTGcaactaaagaaattaaattcaaatttgcCGGACTTAACTAAAGAACAAGTTATTAAAATCATAGAAATTTATAGAGAATTTCCACATCTTTGGAATTCAAATTTGATTGAATTTATTTGTGCAAACAAACGACATGCAGCTCATAATGAAATGTTACAGAGTTTAGAAACAAAATTGGATATAAAAATAAGCGTTGCGTCCTTGGAAGAATATTTACGTACTTTACATTATTATTTCTCAAGAGAAAAATCGAGGAAACGAACGAGAAAACGAACAGCAAAAGATTATTATGAGCATTTGTTGTATTTGTATGATCATGAGGGACCTTTCGACTGCTGCGAATGTAACCGAGTTTTGAGAAAgccattattatttaaaattcataaagcCAGTCATGATGATTCAGTACCATTTATATGTTTACAATGCAATAAAGAGTTTACAACTACCAAGTCGTATACGGTGCATGCTAAACGTCACTTTGAAGATCTCGAATATGCGTGCAATATGTGCGATAAGAAATTCATAGCTTATAATGCTCTAAAATTGCACTTAATAACACACACAAGTGATAGGccatatttttgtgaaatatgtgGAGCTTCATATCGCCAAACGCAAGGCTTAAGTAGACATAAGAGACGACATGAAAAACGATATTCGCACGTATGCCAAATATGCTCTAAAGGGTTTTATTCCAAACAAACCTACGATGGTCACATGAATTCGCATATGAATATACGATCACATGTTTGCGAGTTGTGTGGCAAAGGATTCTTTACCAGAAAAGCATTGAAGACACATGCTGTCACCCATGAAGATGTCAGAAATCATGCCTGCGAGTTGTGTGGAAAAACTTTTAAGCTTAAAATTGGTGTATTACAGCATATGCGAACGCATggcaaaaaatttgaaattgacGATGAAAATTGA
Protein Sequence
MATKMLQVQDYTGYIKCGEILKSPLPYNQYPFILKCVQCDEINFILESFVIHIREHYKDVAEEKGNCDIKNADDYPSQDECIEKSLIKVETIIMEVDDPLVVIKNEKIEEYTHDDADADYNTIEDNEDFEDNSCDSDEDFNTDDAETDDDDINYDLSNKKRKKSFKNTLPSNIENFIKCKENMCTLIELYKNQPNLWKKDLPFYGLKDKRQSFLEETTKELNDKLNLEIKWKEVSDIISYIYRKQRIDFRKLRRYEEENQNAKAKTYKTCWFFDDVDFLRPKPVVQLKKLNSNLPDLTKEQVIKIIEIYREFPHLWNSNLIEFICANKRHAAHNEMLQSLETKLDIKISVASLEEYLRTLHYYFSREKSRKRTRKRTAKDYYEHLLYLYDHEGPFDCCECNRVLRKPLLFKIHKASHDDSVPFICLQCNKEFTTTKSYTVHAKRHFEDLEYACNMCDKKFIAYNALKLHLITHTSDRPYFCEICGASYRQTQGLSRHKRRHEKRYSHVCQICSKGFYSKQTYDGHMNSHMNIRSHVCELCGKGFFTRKALKTHAVTHEDVRNHACELCGKTFKLKIGVLQHMRTHGKKFEIDDEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-