Basic Information

Gene Symbol
Sall3
Assembly
GCA_963678705.1
Location
OY783218.1:12197887-12202146[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.012 0.76 11.4 8.2 1 23 169 191 169 191 0.99
2 18 3.5e-05 0.0023 19.3 0.6 2 23 198 219 198 219 0.97
3 18 0.011 0.72 11.5 2.2 5 23 228 246 226 246 0.97
4 18 1.6e-05 0.0011 20.4 0.3 1 23 254 276 254 276 0.98
5 18 4.1e-07 2.6e-05 25.4 0.4 1 23 282 304 282 304 0.99
6 18 0.00019 0.012 17.0 0.1 1 23 310 333 310 333 0.95
7 18 0.00016 0.01 17.3 6.4 1 23 339 361 339 361 0.97
8 18 4.5e-05 0.0029 19.0 0.3 2 23 366 387 365 387 0.98
9 18 1.6e-06 0.0001 23.6 0.2 1 21 393 413 393 414 0.96
10 18 0.049 3.2 9.4 3.1 1 23 509 531 509 531 0.94
11 18 0.0043 0.28 12.7 0.3 2 23 538 559 538 559 0.96
12 18 0.027 1.7 10.2 4.7 1 23 565 587 565 587 0.98
13 18 2.4e-06 0.00016 23.0 0.3 1 23 595 617 595 617 0.96
14 18 3.9e-05 0.0025 19.2 4.4 1 23 623 645 623 645 0.99
15 18 0.00077 0.05 15.1 0.1 1 23 651 673 651 673 0.97
16 18 1.9e-05 0.0013 20.1 0.8 1 23 679 701 679 701 0.95
17 18 0.0013 0.081 14.4 2.6 1 23 707 729 707 729 0.98
18 18 4.9e-08 3.2e-06 28.3 0.4 1 23 735 757 735 757 0.98

Sequence Information

Coding Sequence
ATGTTCACCGCTAACACTTGTAGAGCATGTTTATCAGGCCAATATGAAACTGAGTTCCTATTTTCAAACAACTTTGATGTTATGTTTAAAAGTTGTACCAGTTTAGAGGTTCAAGAGACTGATGGCCTACCCACCAGATTGTGTCATTCGTGTGCAAACCGGATTGAagcgttttatttatttaagaatgaatgtatacTTAATGATGAGTTTTTACGAAAACAGTCTTTAGAGTTAAAAAAGGAAGATGAAGTTTTACCTATGCAGAAAAATGAGGATGTTATTTTGATTGAACggaaaaatagtaatgatgttgATGATAATGaatattgttttgataaaaatgACAACTCCTCTAACGATGATTCTTTTGACGATGAAGATGATGTAcctttaaaaataagaaataatataacaaagattGCTACATGTATAAAAGCAATAGGGCGTTCTGGAAGACCCTTAAAACGAAATGAAAAGAGAGACGTGTcacataaacataaatttaaatgtgaacACTGTACAAGGCGTTTTAAAACTGAGGAACGATGTGAAAGACATATGAGAACACATTTTGGAAAAGAGaGCGCTGAATGCGAACTCTGTCATAAAAGCTTTAGTAGTATTTATGCTCTAGAAGTACATATGAATTTGCATATGGGTAAAAAGGATTTTGTTTGTCATTGTGGGAAGGAGTTCTTTACGAAATATACCTATGGGATACATATGAAAACTCATGAAGGTAATGAAGGCCGAACATTCGTCTGTGAAAAATGCGGAAAAGGATTTTATTCAAAAGCCAATTTAATGGGTCATAAAATGGTTCATATGGAAGAAACTCCATATCAATGCAATCAATGTCcaaaagcatttaaaaataatggttCACTCCAAGCACATTTATTACGGCACTCAAATGTTAGAAATCACATATGTGCTGAATGCGGAAAGGCGTCTGTAACATTAGCTGAATTAAGAATACATATGCGTAACATTCATTCGGATTTAAGACCTTTTTGCTGTGATGTGTGTGGAAAACGTTGTAAATTAAGGTCTCATCTTACAGCGCATATGCAAATTCATACTGAGAGAAATAAATGCCAAACATGTGGGAAAATATTTGCTACTGGTGGTACATTAAAAATTCATCAAAGAGTACATACTGGAGAGAAACCTTTTAGCTGTAACATATGTGATAGACCGTTTTCACAAAGATCTGCTTTGAAAACACATATGAAAGCAGAAGAAGGTGATGATTTTCCTAGCGCAATATGTATTTCTTGTGCAGAAAAAATTAAAGGATTTAATGCATTTAAGGAAATGTGCGTGGAAAGTTATTCGATTTTGAAGGAGCAGTATTTAGATGTTACTGATGAAAGTTCTAATGATGAAAATTCGTCCTCTGAGTTCGAAAATGATGAGTCTGATGATACAGAAATTGATGTAGATCAGAAGCGAGACAAATTATTTGGAAAAACCAAAACTAAAAACAAGGATTCGCGAACAATCGTCGGGCGGTATATTTATCAATGTTCAAAATGCCCCCGTAAATTCAAAACTGAAGAACGTTGTGAAAGTCATATTGGAACACATTTTGGCAAACCAgaAGCCGAATGTAAAATATGcggtaaaatatttcaaaaatggtTTATATTAGAACAACACATGGTGCGTCATTCTGGAAAACGGGATTATATATGTGAACATTGtggaaaagaattttattttattcatccATATAAAATGCATCTGAAAAAGCATGATAATGATGAAGGAAGAATATTTATATGTGATGAATGTGGAAAAGGTTTTCGTTCTAGTTCCGAGCTTAGAattcatAAATCAATTCATTTAGAAGATACACCATTTCAATGTTCAAAATGTACAaaagcttttaaaaataaaggctGCTTGTCTGCACATTTAAAACGTCATGAAAATGTAAGGAATCATGTTTGCGCAGAATGTGGAAAAGCAACTCTTACAGCAGCTGAGTTAAGAATACATATGCGTTCCCATTCTGATGATAAACCATTTCTTTGCGTTATTTGTGGAAAATCATTTAAAGGCACGTCACAACTAAAGGAACACAGTAGAACTCATAGTGGAGTTAAAAGTCATAAATgtgatatttgttttaaattgtttgCTACGGGCACAACGTTAAAAACCCATCAGAGAGTTCACACAGGTGTAAAACCATATGTGTGCGATATATGTGATCGACCATTTTCACAAAACTCGTCGTTGAAAACGCACATGAAAATCCatgctaaaatataa
Protein Sequence
MFTANTCRACLSGQYETEFLFSNNFDVMFKSCTSLEVQETDGLPTRLCHSCANRIEAFYLFKNECILNDEFLRKQSLELKKEDEVLPMQKNEDVILIERKNSNDVDDNEYCFDKNDNSSNDDSFDDEDDVPLKIRNNITKIATCIKAIGRSGRPLKRNEKRDVSHKHKFKCEHCTRRFKTEERCERHMRTHFGKESAECELCHKSFSSIYALEVHMNLHMGKKDFVCHCGKEFFTKYTYGIHMKTHEGNEGRTFVCEKCGKGFYSKANLMGHKMVHMEETPYQCNQCPKAFKNNGSLQAHLLRHSNVRNHICAECGKASVTLAELRIHMRNIHSDLRPFCCDVCGKRCKLRSHLTAHMQIHTERNKCQTCGKIFATGGTLKIHQRVHTGEKPFSCNICDRPFSQRSALKTHMKAEEGDDFPSAICISCAEKIKGFNAFKEMCVESYSILKEQYLDVTDESSNDENSSSEFENDESDDTEIDVDQKRDKLFGKTKTKNKDSRTIVGRYIYQCSKCPRKFKTEERCESHIGTHFGKPEAECKICGKIFQKWFILEQHMVRHSGKRDYICEHCGKEFYFIHPYKMHLKKHDNDEGRIFICDECGKGFRSSSELRIHKSIHLEDTPFQCSKCTKAFKNKGCLSAHLKRHENVRNHVCAECGKATLTAAELRIHMRSHSDDKPFLCVICGKSFKGTSQLKEHSRTHSGVKSHKCDICFKLFATGTTLKTHQRVHTGVKPYVCDICDRPFSQNSSLKTHMKIHAKI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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