Basic Information

Insect: Pammene aurita
Gene Symbol: Bcl11a
Assembly: GCA_947086415.1
Location: OX352313.1:13264369-13273471[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0001 0.012 17.5 3.6 1 23 174 196 174 196 0.98

2 7 1.3e-06 0.00015 23.5 1.6 1 23 202 224 202 224 0.97

3 7 1.9e-05 0.0022 19.8 2.9 1 23 234 256 234 256 0.97

4 7 2e-05 0.0022 19.8 2.2 1 23 262 284 262 284 0.97

5 7 1.9e-06 0.00021 23.0 2.0 1 23 290 313 290 313 0.97

6 7 7.2e-06 0.0008 21.1 0.5 1 23 319 341 319 341 0.98

7 7 0.019 2.1 10.4 7.2 1 23 347 370 347 371 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0001	0.012	17.5	3.6	1	23	174	196	174	196	0.98
2	7	1.3e-06	0.00015	23.5	1.6	1	23	202	224	202	224	0.97
3	7	1.9e-05	0.0022	19.8	2.9	1	23	234	256	234	256	0.97
4	7	2e-05	0.0022	19.8	2.2	1	23	262	284	262	284	0.97
5	7	1.9e-06	0.00021	23.0	2.0	1	23	290	313	290	313	0.97
6	7	7.2e-06	0.0008	21.1	0.5	1	23	319	341	319	341	0.98
7	7	0.019	2.1	10.4	7.2	1	23	347	370	347	371	0.95

Sequence Information

Coding Sequence: ATGGAGTTACATTCGTGTAGCTGCTGCCTGCTGCGGCCCCCGGACAAGGGGCTCGCTACTCTGTACAACCATTACGGCAAAACGGAGGTATACTCCGACATGCTAAGAGATTGTTTTGATATAAATCTTATCTTAGGAAATGATGAGTATGGAATCTGTGAGGTATGTGTGGGCCGCCTGCGAGATGCGAGTGAATTTAAACTGCAAGTGAAGTGCAGCCAGGCAAGGATACATGCACAGATGCAAACAGCAGTATCTGATACTAATAAGATGGAGGATGTTTCCCCAAACAATAAGCTTCAAACAGATGATAATGCTTCCAAGCACCTCAATATAAAATTGGAACAAGCTTCTGGAGATGAGTCTGTCATACGTGAAATCAAATTGGAAAAGTCAGATGATGACAAGCCTGATGGAGAGATCGAATCAGTGGCATTATATAGTGAGGAACCCACACCGGCGGCTGCCGCTACATGCGACTCGCCGGAACCAGCTCCGGCCTCGTCCGCGGACGCGGCACACACATGCGACATTTGCCTCAAGGCTTTCGACCACCAATCGCGGCTCAAAGTCCACCGCCGCATACACACCGGAGAGAAACCCTACTCGTGCAGTATTTGTAACAAGAAATTCGCACAAAAGGGGAATTTAAACGCTCACTTCAAATACCATATGGACACACACATGGGTAAGAAACCACATATGTGCGAAATATGTAGCAAACGTTTCACATTAAAAAGTACCTTAAGAGCTCACCGAGAAACGCACAGCGAAGAAAGGCCATTTGCCTGCCAAATATGTAATAAGGCTTTCAGGCTAAGCAAATGTTTACAGGACCATATGAAGGTACACGAGGACTTTAAGCAACATTCATGTGAAGTATGTGGTCAGCAGTTTAGGCATAAATCTGCTTTAATAGTTCACATTCGAAGACTCCATCTGAGAGAGAGGCCCCATACTTGCGATGTCTGCGGTAAGAATTTTCCAGTTCTTGCTGAATTGAAAACGCATTATCGTGTGCATACTGGTGAGAGGCCGTACGCGTGTTCTGTTTGCCATAAGAAATTTCATCGACACGACGGCATCAGGAGACATCTCATACGAGTCCACCATGAGAAACCCACGAAATATATTAAAGTAAAAGAATTTTCTGACAATTGCTAA
Protein Sequence: MELHSCSCCLLRPPDKGLATLYNHYGKTEVYSDMLRDCFDINLILGNDEYGICEVCVGRLRDASEFKLQVKCSQARIHAQMQTAVSDTNKMEDVSPNNKLQTDDNASKHLNIKLEQASGDESVIREIKLEKSDDDKPDGEIESVALYSEEPTPAAAATCDSPEPAPASSADAAHTCDICLKAFDHQSRLKVHRRIHTGEKPYSCSICNKKFAQKGNLNAHFKYHMDTHMGKKPHMCEICSKRFTLKSTLRAHRETHSEERPFACQICNKAFRLSKCLQDHMKVHEDFKQHSCEVCGQQFRHKSALIVHIRRLHLRERPHTCDVCGKNFPVLAELKTHYRVHTGERPYACSVCHKKFHRHDGIRRHLIRVHHEKPTKYIKVKEFSDNC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -