Basic Information

Gene Symbol
-
Assembly
GCA_958295655.1
Location
OY282451.1:10661788-10665142[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 7 3.5e+02 1.9 0.5 2 11 37 46 36 49 0.91
2 13 0.011 0.57 10.7 1.1 1 23 347 369 347 370 0.95
3 13 0.0049 0.25 11.9 7.6 1 23 386 408 386 408 0.98
4 13 1.8e-05 0.00091 19.5 2.5 1 23 415 437 415 437 0.98
5 13 0.0002 0.0099 16.3 0.6 1 23 443 465 443 465 0.97
6 13 0.00013 0.0064 16.9 1.2 1 23 472 494 472 494 0.98
7 13 0.00022 0.011 16.1 0.6 1 23 500 522 500 522 0.97
8 13 3.2e-05 0.0016 18.8 0.3 1 23 528 550 528 550 0.98
9 13 1.4e-05 0.00068 19.9 0.7 1 23 556 579 556 579 0.96
10 13 5.9e-05 0.0029 17.9 2.0 1 23 585 608 585 608 0.95
11 13 1.5e-05 0.00074 19.8 0.5 1 23 614 636 614 636 0.98
12 13 0.0015 0.073 13.5 1.1 1 23 642 664 642 664 0.96
13 13 0.00032 0.016 15.6 0.5 1 22 670 691 670 694 0.92

Sequence Information

Coding Sequence
ATGTCCTTCAGCTTATCGGCGTCATCGGTGAATATTGATTCTATGGTATTGGAAGTGGGCAATGATTATAGAAGCAATGCAAGCGAACTAAGTCCTGACTATATTGTTAAATGTTTCCTATGTGATCACACCTTTACGGAAGGTGAAAATTCTTGGTTGGTATTCGAGAAACGGATACAAGACGATGGGCAAATGGACAGTTCATTAGCTGCTATATTGTCGTCGGCACTGGGGCTAGATTTAAAGGAAGTGTCAGCGCATTCTAAActacTTTGCAGTGATTGCAACAATGTTGTATTAGAATTTGAAAGACTAGAGCGGAATTTCTGTGATATTCGGTATCGAATTCTCAGCACTTACAACCGCACAGCACGTCGTAACGATCTTGATCCAATTACAGTTGAAATTAATGGTGTACTCCAGGATACAGAAGTCTATGATACTGATCTAAATAAGAAATGTCGTAAGGAGGTGAATGACTTCCATGATATAATCCCACAAAAACCGAATGCAATCGAATTAATACAGGAAAATGCATTCTATTCCAATTCTGACCTTGAAAATGATCTTGTAGAAGAGGTTAATGACGATTATGAAAGCGAGACCTACTTGCAGGATAATCCTAGTGATTACGCATTTGCAGTGATTCCAAAAAGCAAACCATCTGTTGTGTCAGAGTTCACTTTGGACGAGAGTGAATTAGATGTTGAAGAATTACCAATTAATGAGCAAGATATTATCATCTATGATGAAACCACGGAACAGAGTTCTCAATCATGTTATAAAGAGGAAGATAATAGTTCTATTAGGCAATTGGCTCAAGAGGAATGCAGCAGTATTCATGGAGACACTTTTAATACTCAAGATGTCAGTGAGCAAGAAACTTGTTTTGTACGCACGCCTCGCACGATACGTGGCGCCAAGCAGCTctatgaacaacatggaaacatGACTATTTGCCTTATTTGTGATGATCGCCCAGAGATGGAGGCCAAATTATTTGCCGATCATTTTCGCAACTTTCACAATACAAGATTTTACACATGTGAACTGTGCGACAGTGGATTTTTACGTCGTCAAAATCTTAACGATCACATGGATGAACACCATAATACTAAGTGTGATGGTGAATATAATAGCGGCAGTGCCGCTGAATTCGAATGCGAAACGTGTCATCGACACTTTACAAACTATAGGCTATTTCGCATTCATAAACGTATGCATTACAGTAATGCAAAGCATTATGATTGTAACGAATGCCACAAAAagtataattcaaaaaatttattagaagaACATATGAATATGCATACTGGAGAAAGACCTTTTAAATGCATCAAATGTCCAAAAGATTTTGCATCTAAATATACACTACAAGCACATGTTAAGATACACTCCGAACGTCAGCGGCCATTCCGGTGTAATCAATGCGGCAAAGCGTTTCTCAATCAACAAAATCTAGCACAGCATAAAAAGTTGCACGTTGGTGTCAAGTCATTCATGTGTGATGTCTGCTCGAAAGCTTTTGGAACACAACATAATTTGGATGTACACAAGATTGTGCACACTGGCCAACGACCATTCGTTTGCCGAACATGTGGAAAATCGTTTGCCCGTCGTGCTGAAATTAAGGATCATGAACGTATACATACTGGCGAGAAGCCATTTGCATGTGACATATGTTCGTTATCATTTGCTCAACGTTCTAATCTCATGTCCCACAGAAAATCAACTCACCTCAATGAAAAACTGCATAGATGCGACCAGTGTGACCGCTCCTTTAAGCGACGTCGTTTACTTTTGTATCATATTAATGCAGCGCACACCGGCGAACGTCCTTTCAAATGTAATGTGTGCGGCGCCGCATTTGTGTACCCTGATCATCAGAAGAAGCACATGCTTATACATGCTGGAAAGAAACCATATGCATGCGAAGTTTGTGGCAAAGGATTTTATAATTGCGTTAATAGAAATGCTCATCGTTTTGTGCATAGTGATAAAAAACCTTACGAGTGTGTTGAATGTGGTGTTAGTTTTATGCGGAAACCAATGCTACTGAATCATATGAAGCACGCGAAGCACATTAATGACACAATTATTATAAATCAACCACAAATTAAGGAACTTCAAGACGACATGCTAGAAATGTCTAGATATGAAATCAAATTTGTTGACGCACCTAGCAATGCGAATGAAGATGAACTGGTTGTCGGTGATAAATCATTCGAAAATATAATGCAAAGTACCAAGAGTATATTAACGAATACAGAAAATGAAGGCTGTGAGGATAACGATGATGCTATCAATAGTGTGAGTGGACAATTGATTAAAGACCAAATTGGCGacgtaaaatatttacaattcgaGGATCTCGATAAAGATGGCCATCAAACGCTGACTTGGGTTGATATAGGTGGTAATGAAAAGGACGTCATCTTATAA
Protein Sequence
MSFSLSASSVNIDSMVLEVGNDYRSNASELSPDYIVKCFLCDHTFTEGENSWLVFEKRIQDDGQMDSSLAAILSSALGLDLKEVSAHSKLLCSDCNNVVLEFERLERNFCDIRYRILSTYNRTARRNDLDPITVEINGVLQDTEVYDTDLNKKCRKEVNDFHDIIPQKPNAIELIQENAFYSNSDLENDLVEEVNDDYESETYLQDNPSDYAFAVIPKSKPSVVSEFTLDESELDVEELPINEQDIIIYDETTEQSSQSCYKEEDNSSIRQLAQEECSSIHGDTFNTQDVSEQETCFVRTPRTIRGAKQLYEQHGNMTICLICDDRPEMEAKLFADHFRNFHNTRFYTCELCDSGFLRRQNLNDHMDEHHNTKCDGEYNSGSAAEFECETCHRHFTNYRLFRIHKRMHYSNAKHYDCNECHKKYNSKNLLEEHMNMHTGERPFKCIKCPKDFASKYTLQAHVKIHSERQRPFRCNQCGKAFLNQQNLAQHKKLHVGVKSFMCDVCSKAFGTQHNLDVHKIVHTGQRPFVCRTCGKSFARRAEIKDHERIHTGEKPFACDICSLSFAQRSNLMSHRKSTHLNEKLHRCDQCDRSFKRRRLLLYHINAAHTGERPFKCNVCGAAFVYPDHQKKHMLIHAGKKPYACEVCGKGFYNCVNRNAHRFVHSDKKPYECVECGVSFMRKPMLLNHMKHAKHINDTIIINQPQIKELQDDMLEMSRYEIKFVDAPSNANEDELVVGDKSFENIMQSTKSILTNTENEGCEDNDDAINSVSGQLIKDQIGDVKYLQFEDLDKDGHQTLTWVDIGGNEKDVIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-