Basic Information

Insect: Pachypsylla venusta
Gene Symbol: ZEB2
Assembly: GCA_012654025.1
Location: CM022878.1:2228411-2233037[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.0029 0.27 12.0 2.9 2 23 4 26 3 26 0.95

2 21 7.5 7e+02 1.2 0.5 2 11 69 78 68 91 0.80

3 21 0.046 4.3 8.2 2.8 6 23 109 127 103 127 0.90

4 21 4.5 4.2e+02 1.9 0.8 11 23 244 257 230 257 0.82

5 21 0.79 74 4.3 0.1 1 23 284 306 284 306 0.96

6 21 0.00013 0.012 16.3 6.3 1 21 312 332 312 335 0.94

7 21 1.7e-05 0.0016 19.0 6.8 1 23 341 363 341 363 0.97

8 21 0.1 9.7 7.1 0.2 1 13 369 381 369 386 0.89

9 21 3.5 3.2e+02 2.3 6.4 3 23 387 407 385 407 0.94

10 21 0.0034 0.31 11.8 0.1 1 23 452 475 452 475 0.94

11 21 0.88 83 4.1 0.7 6 23 494 512 488 512 0.85

12 21 0.00083 0.077 13.7 0.9 1 23 577 600 577 600 0.95

13 21 6 5.6e+02 1.5 3.2 1 23 613 637 613 637 0.88

14 21 1.8 1.7e+02 3.2 0.1 10 23 747 761 736 761 0.80

15 21 0.0014 0.13 13.0 0.0 1 23 790 812 790 812 0.99

16 21 1.7e-05 0.0016 19.0 2.2 1 23 818 841 818 841 0.97

17 21 4.7e-09 4.4e-07 30.2 1.2 1 23 847 869 847 869 0.98

18 21 0.00053 0.049 14.3 0.2 1 23 875 897 875 897 0.97

19 21 1.3e-08 1.2e-06 28.8 1.7 1 23 902 924 902 924 0.99

20 21 1.3e-05 0.0012 19.3 0.4 1 23 930 952 930 952 0.97

21 21 0.00019 0.018 15.7 2.4 1 23 958 980 958 980 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.0029	0.27	12.0	2.9	2	23	4	26	3	26	0.95
2	21	7.5	7e+02	1.2	0.5	2	11	69	78	68	91	0.80
3	21	0.046	4.3	8.2	2.8	6	23	109	127	103	127	0.90
4	21	4.5	4.2e+02	1.9	0.8	11	23	244	257	230	257	0.82
5	21	0.79	74	4.3	0.1	1	23	284	306	284	306	0.96
6	21	0.00013	0.012	16.3	6.3	1	21	312	332	312	335	0.94
7	21	1.7e-05	0.0016	19.0	6.8	1	23	341	363	341	363	0.97
8	21	0.1	9.7	7.1	0.2	1	13	369	381	369	386	0.89
9	21	3.5	3.2e+02	2.3	6.4	3	23	387	407	385	407	0.94
10	21	0.0034	0.31	11.8	0.1	1	23	452	475	452	475	0.94
11	21	0.88	83	4.1	0.7	6	23	494	512	488	512	0.85
12	21	0.00083	0.077	13.7	0.9	1	23	577	600	577	600	0.95
13	21	6	5.6e+02	1.5	3.2	1	23	613	637	613	637	0.88
14	21	1.8	1.7e+02	3.2	0.1	10	23	747	761	736	761	0.80
15	21	0.0014	0.13	13.0	0.0	1	23	790	812	790	812	0.99
16	21	1.7e-05	0.0016	19.0	2.2	1	23	818	841	818	841	0.97
17	21	4.7e-09	4.4e-07	30.2	1.2	1	23	847	869	847	869	0.98
18	21	0.00053	0.049	14.3	0.2	1	23	875	897	875	897	0.97
19	21	1.3e-08	1.2e-06	28.8	1.7	1	23	902	924	902	924	0.99
20	21	1.3e-05	0.0012	19.3	0.4	1	23	930	952	930	952	0.97
21	21	0.00019	0.018	15.7	2.4	1	23	958	980	958	980	0.98

Sequence Information

Coding Sequence: ATGGTGTGGTCGTGTTGTAAATGTAACGCCAAGTTCAATTCCTCTTCACATCTTGATTCTCATATATTAATTCTTCATTCCGGTGGTGGTGATTTAGACACAAAAACTTCTCTTGGCGAGGAATCTAGTACTTGTGTATTGTGTTACTCGTCACTTGATTCGCATTCCTCGCGACAAACAAAACTCTCGTCCAAATCATTTTCCAGCTGTTTCCACTGTAATCAAATATTTACCGctacaaaaatattagaatttcatattaaaattgaacattCCCAATCTATGTTTAGAGATCCTGTCGTTTGGTATGCATGTCGAATGTGCTGCGATAAATTGTATAGGAGAACATCGGATTTTCGTAAACACATGCAAAATATTCATAACATGTTTCATATTAATGTCGATGAGTATTGTGTGAAACATTCGGGCGAGGTACTTTTTCCTTGTCACACATGTGGTCAGTTGAGCGCATTATCAAAAACATGTGAAAAACACAGTGTGATTCCTGTTTCCTTGAAATCATCGGCAAACTCGAATCGAACCTTCGCTGATGATACAAATTCCTGTACGATTCTAAAACATTTGGCCAATCAACATGTGTGCGTCAAATGTGGCGGTGTTCCGTTCGATAATTGTGATCAACTTTGGTGTCATTTGTTTGACAAACATCGTGATACAGATTTTGGATGTAATCTATGTCCAGTTTCGCCTCATACGAAAGTTGTTCTCAAATATGAACATCTCCTTGTTCGTCATATGAAGAAATATCATTCTTTACAATTGAAAATTccttctaattttgataaattaagaTCTCAAACCCGATGTACTATCAATGGTGTCGAACATTATAAATGTTTAGATTGTTCAACGATTCTACAAACGTTTCGTGGTCTTATCGGACATTTAGAAATACACAGCGGAGAAAGATCTTTTGTTTGTAACATTTGTGACAAACAATTTCGACGTAATTCAGATCTGTGTCATCACGTCAAATGTGTTCATGACAATGTTCGCGAACATCAATGTACATTTTGTGGGAAAACGTTTGCTACGAAATCTCATTTGAAATTACATGTTCATATTCATACGAATGAACGAAAATATGTTTGCGAACAATGTGGTGCGTCGTTTGTTCAATGGTGTGCTGTGTGGGCGTGTTGTTCTTGTACCGCTAAATTCACCTCTTGCACACATCTTAGTCTTCATCTTCTCTTACACACTAGCACCTCTTCCTCGTCCAACACAGTCTCAACCAATGGTCGTCATTATCAAGACATCTGTTTTCTATGTAACTATTCAATGGAAACACATCAAATTGAGGAAgaatcaaaacttaaaaaagatgatatttttctttgttcttaTTGTGCTGGCAATTTTTCTGATAAAACCATGTTAGAAGTCCACATTAAAATCGAACATGGCCGAATTGTTTACGATAATGATCAGTTGTGCTGGTACGCATGTCAGATATGTTGTGGAAAGCTTTACATGAGAAGTCAGGATATAGTTAAGCATATGAAGCTCATCCATCAGGAAGAATATTGTCGGTCTGAGAATTACATTGTGTCTTCTATTGAGGATGTTGTGTATCCGTGTGAGCAATGTGGGGAACCAAGTGTCATGTCGAAACGGTGTTCAAAAcataaaaagaacaaatttttaaataggaaaatctcgaagaaaaaacaacaacgttgTCGAAACATATCGGAATTGGTTGAACATATGTGTTGGTATTGTGAGCAAAGTTTTCAGCTGAAAGATTCTCTTGAAGCACATATTAAATTAACACATGGCCATATTGTCTATGGCAATCCAGATCTTGTCTGGTATTGCTGTAATGTATGTTGCGATCGATTGTACATGCGCAGTCAGGATATAGTTAAACATATGCGAAATGTTCACGGCAAACTTCGGATTCAAACGAATGATTTCATTGTTCGTTCACAGTTAGATGTTACATGGACATGTATTCAATGTGATAAGATGTGTATTTTATCGAAAACTTGTGAAGATCATaaggagaaaataaaagaagaacgTTTGACGGAAAGTTACGAAGAATGTTCGTCCGTACCGAGTGAATGCGAAGAGcatgaatatttaaaatgtcATTCGTGTCAGTGTTGTGATTGTTTATTCGACGAATGTAATCATTTGTGGTCTCATATGTTTTCTGAACATCGAACAAAACGAAAAATATGTAATCTCTGTACGGATATAAATGTGATAGTGAAAAGTGCAACGTTTCTAACGAGACATATGAATAAAGTTCAtagaaaaagtttaaaacttCAAATTACTCCTCGAAATgatgatttaaaagaaaaatctcgaCTTGTTGTCGATGGTACGGAAATGTACAAGTGTCCAGAGTGTGGAGCActtcttaaaaatatttggagtttACGAGAACATATTATGATACACACGGGAGAAAAACCGCATGTGTGTGATGTTTGCAGTAAATCATTTCGAAATCGAGGAAAACTAAATGTTCATTATAAGCGAGTACATGAACAAGTCCGTGAACATCAGTGCGGCTATTGTGGCCGAGCGTTTTCAgataaatctaatttaaatgtacACATTCGCACACACACAGACGAGAAGAAGTATATGTGCGAACTATGTGGCGCTGATTTTGCACAATGGGCGACACTCTACAATCATAAATTTACGCATAATAATGTTAAATTCAAATGTACTTACTGTGAAAAAGTTTATAATAATCCGAGCAATTTACAAAGACATATTAAAACCCATACGGACAATTCGTTGTATATCTGTGAAGTTTGTGGCAAAGATTTCGGTACGGCTCGATATTTGAAGCGACATAAAGATACGCATAATTCGGTGAATGCGTTTGTTTGTGAGGTGTGCAATGCgggatttaaaataaaaaaacatttgactcAACATTATAAGACGCATTCGATATTCGTTCCTCCGGAGCAATATTCGTTGATGAATCCAAATAATGCAAACAACTGTGAACGAACGCTGTACAAACTGTAG
Protein Sequence: MVWSCCKCNAKFNSSSHLDSHILILHSGGGDLDTKTSLGEESSTCVLCYSSLDSHSSRQTKLSSKSFSSCFHCNQIFTATKILEFHIKIEHSQSMFRDPVVWYACRMCCDKLYRRTSDFRKHMQNIHNMFHINVDEYCVKHSGEVLFPCHTCGQLSALSKTCEKHSVIPVSLKSSANSNRTFADDTNSCTILKHLANQHVCVKCGGVPFDNCDQLWCHLFDKHRDTDFGCNLCPVSPHTKVVLKYEHLLVRHMKKYHSLQLKIPSNFDKLRSQTRCTINGVEHYKCLDCSTILQTFRGLIGHLEIHSGERSFVCNICDKQFRRNSDLCHHVKCVHDNVREHQCTFCGKTFATKSHLKLHVHIHTNERKYVCEQCGASFVQWCAVWACCSCTAKFTSCTHLSLHLLLHTSTSSSSNTVSTNGRHYQDICFLCNYSMETHQIEEESKLKKDDIFLCSYCAGNFSDKTMLEVHIKIEHGRIVYDNDQLCWYACQICCGKLYMRSQDIVKHMKLIHQEEYCRSENYIVSSIEDVVYPCEQCGEPSVMSKRCSKHKKNKFLNRKISKKKQQRCRNISELVEHMCWYCEQSFQLKDSLEAHIKLTHGHIVYGNPDLVWYCCNVCCDRLYMRSQDIVKHMRNVHGKLRIQTNDFIVRSQLDVTWTCIQCDKMCILSKTCEDHKEKIKEERLTESYEECSSVPSECEEHEYLKCHSCQCCDCLFDECNHLWSHMFSEHRTKRKICNLCTDINVIVKSATFLTRHMNKVHRKSLKLQITPRNDDLKEKSRLVVDGTEMYKCPECGALLKNIWSLREHIMIHTGEKPHVCDVCSKSFRNRGKLNVHYKRVHEQVREHQCGYCGRAFSDKSNLNVHIRTHTDEKKYMCELCGADFAQWATLYNHKFTHNNVKFKCTYCEKVYNNPSNLQRHIKTHTDNSLYICEVCGKDFGTARYLKRHKDTHNSVNAFVCEVCNAGFKIKKHLTQHYKTHSIFVPPEQYSLMNPNNANNCERTLYKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -