Basic Information

Gene Symbol
-
Assembly
GCA_036926295.1
Location
JAVFKF010000007.1:11843710-11845857[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.046 19 8.2 3.6 1 23 7 29 7 29 0.95
2 12 4.5e-06 0.0018 20.8 1.6 2 23 121 142 120 142 0.97
3 12 3.8e-05 0.016 17.9 2.0 1 20 148 167 148 169 0.93
4 12 0.00064 0.26 14.0 1.3 3 23 176 196 174 196 0.97
5 12 0.00095 0.38 13.5 0.4 1 23 202 224 202 224 0.97
6 12 0.00015 0.059 16.1 0.4 2 23 230 251 229 251 0.96
7 12 0.0054 2.2 11.1 0.0 2 23 254 275 253 275 0.95
8 12 2.6e-05 0.01 18.4 0.7 1 23 296 318 296 318 0.99
9 12 3e-05 0.012 18.2 0.8 1 23 324 346 324 346 0.98
10 12 8.2e-05 0.033 16.8 0.6 1 23 380 402 380 402 0.97
11 12 1e-07 4.1e-05 26.0 1.4 1 23 412 434 412 434 0.98
12 12 0.052 21 8.0 4.4 1 20 440 459 440 461 0.93

Sequence Information

Coding Sequence
ATGCATCCTGATTTGGTGTTTCGTTGCTGCTTCTGCTTGAAGGTTTTTTATGACAAAGAGGAATTTTACACCCATGAGTTGGCTCATCGGAAGCAACTACTGCCTGGATTGAAGGGAAAGTTAGGCTTACGAAAGCTTTCGAAGGGGAATTCTGCCAGAAGCACTTCTAAAGCATTGGATGatgtatctttttcaaaatcaatggGTCAAAAGAGAGATAATAAGTTAAAGGAAGACTCTACCAATAAACTTGACTGTTTAGATGATTTAATTACAAGTCAAGGTATTAATGATGAGGAACATGGTAGTGAAATTGATCTTTTGAAGGAACATAAACTCTCTCATGAAGGGGAAGATCTCAAGTGTGAGGTTTGCAACAAATCGTTCACAGGGTATAGGAAGCTCAAGAATCACATCCAGACTCATTCAGTTGGAAGGAATTATTTGTGTGAGAAATGCGGCAAAGATTTCAAATCTAACTCTAGCCTACATAAACACCGCTATCTCTGCCAAGTTGCCATTGCGTGCACTGTTTGTGGCAAGGAATTTGATTGTAACACACGTCTGAAAGTGCACATGCGAATGCACACTGGAGAAAAACCTTTTGTTTGTTCAGTTTGTGGAAAAGGTTTTCATGCTTCTTGGTCACTAAGTCAGCATTCTGCAACTCATAACACTGTGAAGATACCTTGCCCTCTTTGTGGCGCTCTATTCAATCGGAAGTCAAACATGCTGACTCATAAGAAAAGACATCGTGTTCCATGTGGGGTTTGTGGTAAAGTGTTTGCAAGCATTCCAATTCTGCTGGCTCATCAAAAGTCACATGATGCAAATGGTGATAAAGAGGGTGAAAGTGAAGCTTCTAAAGATGATTCTTCAGTTGCTTTCAGGTGTGAGCAGTGTGGGAAACTTTTTATGACAACTCTAGACTTGAAGGCTCACATGTCAACTCATTCCAATGAGCGCCCTTACAAATGTGATATCTGTGGAAAGAGTTGGAGGCTTCAAAAGACACTCAAAAAGCATATGGTGATGCACAGTGGGCGAAAACCCTATCAGTGTCGCTATTGCACTTGTACATTTTTGCTGCACCAAAGATTAGTGAAGCATGAGAATGGGCACACTGCTGGCAAGCCCTTTTCCTGTCAGGATTGTGGCCAGTCCTTCTGGACTCAATTGAATCTTGAAAAGCATACCATTAGACATTGTGCTATGAAGATTGTAGATCAAAAATATGCATGCAAGGTTTGTGATAAAACTTTTgagacaaaatcttctttaatatccCATAAACGTACACATTCCCATCAACCCCTTTATTGCTGTGCATATTGTCCAAGAAAGTTCTCTCAACTGCGTTATGCCCAAAGGCATAAGTGTGCACTAGATCCAGACAATCAGGTAAAGGATTCCTCAGCTGgagaagtaatatttaaatcCATGCCATCTTTGGCTGAAGATGAATCCTGCAGTCCAGATGAAAATACTTGCCCTGGTGTCCTCAATGAAGAAGTTGTTTATGATATGGACTCTGTTTCTCCATCTTATGCAGAAATTATTGTGATCTCTCAAGGTATGGATGATATTATGGTGGAAAATAGTAATGAATTAGACAACTCTACATAA
Protein Sequence
MHPDLVFRCCFCLKVFYDKEEFYTHELAHRKQLLPGLKGKLGLRKLSKGNSARSTSKALDDVSFSKSMGQKRDNKLKEDSTNKLDCLDDLITSQGINDEEHGSEIDLLKEHKLSHEGEDLKCEVCNKSFTGYRKLKNHIQTHSVGRNYLCEKCGKDFKSNSSLHKHRYLCQVAIACTVCGKEFDCNTRLKVHMRMHTGEKPFVCSVCGKGFHASWSLSQHSATHNTVKIPCPLCGALFNRKSNMLTHKKRHRVPCGVCGKVFASIPILLAHQKSHDANGDKEGESEASKDDSSVAFRCEQCGKLFMTTLDLKAHMSTHSNERPYKCDICGKSWRLQKTLKKHMVMHSGRKPYQCRYCTCTFLLHQRLVKHENGHTAGKPFSCQDCGQSFWTQLNLEKHTIRHCAMKIVDQKYACKVCDKTFETKSSLISHKRTHSHQPLYCCAYCPRKFSQLRYAQRHKCALDPDNQVKDSSAGEVIFKSMPSLAEDESCSPDENTCPGVLNEEVVYDMDSVSPSYAEIIVISQGMDDIMVENSNELDNST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-