Basic Information

Gene Symbol
MAZ
Assembly
GCA_958009045.1
Location
OY253744.1:24168345-24171147[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 2.9e-05 0.0026 18.3 2.5 1 23 112 134 112 134 0.96
2 17 1.7e-05 0.0015 19.1 4.6 1 23 140 163 140 163 0.96
3 17 0.00043 0.039 14.6 1.9 1 23 176 198 176 198 0.98
4 17 0.38 34 5.4 0.4 2 23 204 226 203 226 0.89
5 17 1.4e-06 0.00012 22.5 2.7 1 23 233 255 233 255 0.99
6 17 1.8e-05 0.0016 19.0 1.9 1 23 259 281 259 281 0.97
7 17 0.045 4.1 8.3 0.9 3 23 289 309 287 309 0.93
8 17 9.1e-05 0.0082 16.8 3.0 1 23 315 338 315 338 0.97
9 17 0.0041 0.37 11.6 1.5 1 23 496 518 496 518 0.98
10 17 2.3e-07 2e-05 25.0 1.4 1 23 524 547 524 547 0.97
11 17 0.023 2.1 9.2 1.9 1 23 554 577 554 577 0.94
12 17 7.9e-06 0.00071 20.1 2.2 1 23 583 605 583 605 0.98
13 17 0.017 1.6 9.6 0.1 3 23 612 633 610 633 0.92
14 17 9.1e-05 0.0082 16.8 3.0 1 23 640 662 640 662 0.98
15 17 1.9e-05 0.0017 18.9 0.2 1 23 666 688 666 688 0.98
16 17 0.00037 0.033 14.8 0.2 1 23 693 715 693 715 0.95
17 17 2.1e-05 0.0019 18.8 0.8 1 23 721 744 721 744 0.98

Sequence Information

Coding Sequence
ATGAGTATTtcaccgaagaaaaaaatgtcgataaaaGCGATTGAATCCGTGTCAGAAAAGTTGCAAAATATCGCTGATTCCGGTACCGAGAACGTcgatgaaattgacgaaataatCAATCAAGTGGCGATTGGTTTTTTGCCGGAGACAAAAGTAATGACAGAAGCGACAGAAACGATAGCGCCAAATTTGCGAAATATCGTCGATCGTGGTATCGTTAATGTCGAAAAGATCGAACAACACGACAGATTGTCGATTGATTCTTCGTTGATTACTAAACCGAATGAAAACTCGAAACGTCAAAGAGCGTCGAGGATTAAATCGAAAAAGAGTCATATATGTCAGATTTGTAATAAATCGTTCGCCAAACTCACTAATTTCAACAAGCATCTGATATCACACAGTATCGTGAGACCATTCGAGTGtttgatatgtaaaaaaaaattcaaacacaatTCTACCCTCAAGAGACACACGAGTGTGCAGCACAGCGATGAGGTTGCCGATTACGACAACGAGTACAAGCACAAGTGTACGGAATGTGGTAAATATTTTGATAACGGATTGGATTACACGATGCACATGAAGATACACGAGGCCGGACCGCAAACCTGCAATATATGCGCAGAATCGTATCCGAATATGAGATCACTTTATTATCACAAATATCAGATGCACACGTTGAATAATCAGCGCTATAAGTGTAAAATATGCGACAAGCGTTTCGAGAGCAAGGAACATTTGGATATTCACGTTAAAACGCACAAGCAACGTTACGCGTGTCGCGATTGCGGCGTTACATTTGCCAAAAAGCAGAGCCTAACGAGACATCATAAAATTCACACGGGCGGACAATATCTCGCTTGTAGCGTGTGCGACAAGAGATTCGCTTGTCTCGCATCGTTGAGAGTACATTTTTTGTATCACACCGGCGTCAAACCGCACGAGTGCGATCAGTGCGATCGTGTGTTTAGCCAGAAGTTATCGTTATTGACACACCGAAAGAAACAACATCCCGACACGACGAAAAGAGCGCGATTGCTCGGCGCGATGAGCAACGTCGTGACCTTGGAGTCCAGTTCCGAGCGCACTACCGACGAAAAGAAGAGCGGTCGACGTAAGAAGAGCGTACCAGCGAGAAAATTGAGGAAATCGGAAGAGACGAGCAAGGCGGGATCGACTGGTTCGAAGCAACATAACGAAAGTACAACGTCGACCGAACAACCGCTGAATCTTAAATCCGTACGTTCGAAGCGTACAGCCGGTACGGCAAACGTCGACGCTGAAAAATCCGATTCCGAGAAGAAAATACCagcgaaaaagagaaaaataacgcGTAAGAATTTGCCGATTAAAAAGACAAAGATAACACGCGAGACGAGCAGCGAGTCGGAGGACAGCGAGAGCTCGCACGAGGAGTGGCAGGATCCTTATGAAAAACCGTCGAAGCCGGTGaaaccgccgccgccgccaaaACCCGATTTTTACGAGTGTTCAACGTGCGAAATGACGTTCGTCGAGCGTCGTCGTTATCGTCGTCATCTAGCTAAGCACAATAACACAAAGAGCTACGAGTGCGAGACTTGCGGACAAAAATTCAAGTACAATTCAAATCTGAAAAGTCACATAAGATACGTTCACGACGAGTGTCCGCCGGTTTACAATTGTACAATGTGCGATTTCACGACAAAAGGACCGTACTATCTGCAGGAACATTTTACGCGCAAGCACACCGAGGAGTACAAGTACGAGTGCAACATATGCGGCAAGCATTACAAGAGCGAGCGTGATTACAAGGCGCACATGAGTAATCACGAGGACGGACCGCAAATTTGCGACATATGCGGTATATCGTATCCGGGCAAGGTGTCACTGTACTCGCACAGATATTACAAGCACACGGAGAAGATGAAACCGTTCGAGTGTACGATATGTAAGAAACGCCTGTGCACGGAGAAGAATCTCGAGTCGCACATGTTGCAGCACAATCAGTCGTACGTGTGCGAGCTTTGCGGTATGAAATTTGGCAGACAGGCCGGCCTCTCGAAGCATCGTAAAATACACGCGGAGAAAACTTTTCTCTGTACCGTTTGCGGACGTGCTTTCGCGAATATGACGACCCAGAGGGTACATATGATAACGCACTCGGGCGTTAGACCGTACTCGTGCGACGTTTGCGGCTCGAGTTACACACAGAGATCGTCGTTGATGCTTCATTGGAGAAAGAAACATCCCGAGGCAACTGAACCACCGCCACCCGTGACACTCACGAATATatccgattttttgaaaccGAATGCAGACTGA
Protein Sequence
MSISPKKKMSIKAIESVSEKLQNIADSGTENVDEIDEIINQVAIGFLPETKVMTEATETIAPNLRNIVDRGIVNVEKIEQHDRLSIDSSLITKPNENSKRQRASRIKSKKSHICQICNKSFAKLTNFNKHLISHSIVRPFECLICKKKFKHNSTLKRHTSVQHSDEVADYDNEYKHKCTECGKYFDNGLDYTMHMKIHEAGPQTCNICAESYPNMRSLYYHKYQMHTLNNQRYKCKICDKRFESKEHLDIHVKTHKQRYACRDCGVTFAKKQSLTRHHKIHTGGQYLACSVCDKRFACLASLRVHFLYHTGVKPHECDQCDRVFSQKLSLLTHRKKQHPDTTKRARLLGAMSNVVTLESSSERTTDEKKSGRRKKSVPARKLRKSEETSKAGSTGSKQHNESTTSTEQPLNLKSVRSKRTAGTANVDAEKSDSEKKIPAKKRKITRKNLPIKKTKITRETSSESEDSESSHEEWQDPYEKPSKPVKPPPPPKPDFYECSTCEMTFVERRRYRRHLAKHNNTKSYECETCGQKFKYNSNLKSHIRYVHDECPPVYNCTMCDFTTKGPYYLQEHFTRKHTEEYKYECNICGKHYKSERDYKAHMSNHEDGPQICDICGISYPGKVSLYSHRYYKHTEKMKPFECTICKKRLCTEKNLESHMLQHNQSYVCELCGMKFGRQAGLSKHRKIHAEKTFLCTVCGRAFANMTTQRVHMITHSGVRPYSCDVCGSSYTQRSSLMLHWRKKHPEATEPPPPVTLTNISDFLKPNAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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