Basic Information

Insect: Oxycera nigricornis
Gene Symbol: ZEB2
Assembly: GCA_963942545.1
Location: OZ012662.1:25789145-25796640[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.11 21 7.4 2.2 1 23 328 350 328 350 0.96

2 8 0.019 3.7 9.7 0.6 3 20 360 377 358 380 0.92

3 8 0.00023 0.045 15.8 0.5 1 23 389 412 389 412 0.95

4 8 0.00039 0.076 15.1 4.8 1 23 417 439 417 439 0.98

5 8 0.025 4.8 9.4 4.4 2 23 446 467 445 467 0.97

6 8 0.032 6.3 9.0 5.1 1 23 472 495 472 495 0.97

7 8 8.7e-05 0.017 17.1 2.6 1 23 501 523 501 523 0.95

8 8 0.0042 0.82 11.8 2.7 1 23 529 552 529 552 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.11	21	7.4	2.2	1	23	328	350	328	350	0.96
2	8	0.019	3.7	9.7	0.6	3	20	360	377	358	380	0.92
3	8	0.00023	0.045	15.8	0.5	1	23	389	412	389	412	0.95
4	8	0.00039	0.076	15.1	4.8	1	23	417	439	417	439	0.98
5	8	0.025	4.8	9.4	4.4	2	23	446	467	445	467	0.97
6	8	0.032	6.3	9.0	5.1	1	23	472	495	472	495	0.97
7	8	8.7e-05	0.017	17.1	2.6	1	23	501	523	501	523	0.95
8	8	0.0042	0.82	11.8	2.7	1	23	529	552	529	552	0.98

Sequence Information

Coding Sequence: ATGGATTCGGAAAATTATTGCCGATTATGCCTGCACCGAGATCACGTCGTGCTTAATGTATTCAGCGAAGCGATGATGGAGAGTGAAATGCTAGCAAAAATAGAGAAATACTTGTATTTAGAGATAAAAGAGACTGATCTAGCCAAAACGATATGTGTTAATTGTGTTCGAAAAATTGAGGAAACGCATAATTTCTGTGTTGAGGTAATTGTCGGGCTgccgaaaaatgattttttaaacacTTACCGCGAAGCTAGCTCATTGAGTCTTTGTGGGATAGTAGTTGGCATATTGTACTATGTACAAACATGTGTAGCAGTTAATGTGCACCAAAATCAAGAAAAACTGCTCGCGCggcaaaacaaacaacaatttcaaattcTATTCGATAAAAACCAAAGCGCGGATAATGTGTCCGAAGAAGTTAATCACGACGAGCCATACGATATGAACGAAGAATTATATTGTGAGCCAATTATAAACGATTTACATTTTGCCGATGTTACAGCTATACAAAGTCCTGATCGGTCGCCGGAATATCAAATAATGCTAACTGAATCACCCGAAACTAGAATAGTTCATTCGCCGCGACCACCCACGGAAGGCAACGTGAATGAAGTGGATTGTTTCGACACCTTCTCGATAGCTGCTAGTTCAAATGAATACGACGACCGGACCGAGAATGATTTTGATAGCGACAATGAATggaacaaaaatattgaagactTTCCAAAAGTGCTAATCAAAGATGCAAAACTTGCGCTACGTGGACAAGAGCTGTTCAATTTAATGTCTAAGTTTTATAAGCTACAATGTGAAATTTGTCAAGAAAAGGATAGTGTGTTTATCAAGATCGCAAGCCTCTTGGAGCACTATGAAGATATTCACTCGACAGCGGGCTATGTTAAATGTTGTGGTGTGAAACTGATCACAACGCGAAGAATGGCGATGCACATGGCAAAACACGTTCAACCCGATGCATTCACGTGCTCGGAGTGTGGCAAATTAATGAACTGCCCGAAAAATCTACAATACCACATGCTGAACCATTTACCAGAAGAAAAAAGACCTTGGGCGTGTCCAAAATGTCCAAGACGATTTGGTTACAGCGGCGGATTGGCAACTCACAAATTATGTCATCTTCCCGAGGATCAACGGGGGTCTCATAGATGTACTGTGTGCGGCAAAGGgtTCGTGTCCGCTAATCGACTAGCAACGCACGTTAGTATGACACACTCAGTTCCGCGCTATGTGTGTCACGAATGTGGCAAGCAATTTAGCTGTAAAGGTAATCTTTCGTACCACCTTACAACGCACGAAGAGATACATCAAGTCCAATGCACAGAATGTAAAAACTGgtttaaaaataaattttgcctTCGCAAACACATGGCTAAACATTCCGAAGTACGTCACAAGTGTCCTTCTTGTGATTATTCTTCAACGAACCTGCAATGCTATCGAAATCACTTGAAGGTGCAACATTCCAACGATAAACCGCACGTGTGTAAGGAATGCGGACGCAGTTTCAAGCTGAAAAATACACTCCTAAATCATATTTTCCAGCATACTGGCGAACGTAAATATACTTGTGAATTTTGTATGAAACGATTCGCTTCAAGTGGTAACTACTATTCACATCGTAAACGTATGCATCCGAATGAATTGGCCGAGCACAATGAAAAACGCGCCCAAGCGAAGGAGAAAGCTAGGGAGCTAGCGCTTAAGCAAAGGGAAAAAGACGGTACCTGA
Protein Sequence: MDSENYCRLCLHRDHVVLNVFSEAMMESEMLAKIEKYLYLEIKETDLAKTICVNCVRKIEETHNFCVEVIVGLPKNDFLNTYREASSLSLCGIVVGILYYVQTCVAVNVHQNQEKLLARQNKQQFQILFDKNQSADNVSEEVNHDEPYDMNEELYCEPIINDLHFADVTAIQSPDRSPEYQIMLTESPETRIVHSPRPPTEGNVNEVDCFDTFSIAASSNEYDDRTENDFDSDNEWNKNIEDFPKVLIKDAKLALRGQELFNLMSKFYKLQCEICQEKDSVFIKIASLLEHYEDIHSTAGYVKCCGVKLITTRRMAMHMAKHVQPDAFTCSECGKLMNCPKNLQYHMLNHLPEEKRPWACPKCPRRFGYSGGLATHKLCHLPEDQRGSHRCTVCGKGFVSANRLATHVSMTHSVPRYVCHECGKQFSCKGNLSYHLTTHEEIHQVQCTECKNWFKNKFCLRKHMAKHSEVRHKCPSCDYSSTNLQCYRNHLKVQHSNDKPHVCKECGRSFKLKNTLLNHIFQHTGERKYTCEFCMKRFASSGNYYSHRKRMHPNELAEHNEKRAQAKEKARELALKQREKDGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -