Basic Information

Gene Symbol
-
Assembly
GCA_963942545.1
Location
OZ012660.1:102885398-102891446[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.0041 0.8 11.8 2.5 1 19 188 206 188 208 0.91
2 8 0.061 12 8.2 9.0 1 23 217 239 217 240 0.95
3 8 1.5e-05 0.003 19.5 5.8 1 23 245 267 245 267 0.99
4 8 9.1e-06 0.0018 20.2 0.7 1 23 273 295 273 295 0.99
5 8 4.6e-08 9e-06 27.4 2.3 1 23 301 323 301 323 0.98
6 8 4.9e-05 0.0096 17.9 1.5 1 23 330 352 330 352 0.99
7 8 1.5e-05 0.0029 19.5 1.9 1 23 358 380 358 380 0.99
8 8 5.3e-05 0.01 17.8 1.4 1 23 385 408 385 408 0.97

Sequence Information

Coding Sequence
ATGGAGACATCATTTTGTCCGCGATGCAATCGGATGCCAGTGTCCCCGACCAACCGGCTGATAACTGAGCGGTGTGGGCACGTGAAATGTCGCGAATGTTTTATCAATGATTTGGATGGTTGTTACGAATGTCTTCAAGGAAGCACACAATCGATCCCAGATGCTGCGTCCACAATTGAGCGTCGCATCCACCAGCAAGTGGACTGCTTCGAAAACCCGCTGAATATCGAGGGCGACTCGCTTGCTTTGTACAACACAGTAGTTGAAGATTCGGCCACCTTCGAAGGACCTGCGACTACGAAGACCTCAGAACCTACATCGGCTGCAGCCGTTGAACCCGCAAACAGTATCAATGTAATCCACAACTACAGCACCAATGATAGTCAACAGCAGGCAAGCGATTCCACcgaaagtttcaaaattctcGAAGAATACATAATCCCAccgaaaacaaaaattgaaaaattcttcagGGAAAGAAAAAGCTTGTCTGGACTGTACGAACGAAAGAAAGGAGTTCCTGACTATGTCGAGAAATCTGTCGAGGGTGGCGAGACGTTTTACAAGTGTAATGCTTGCGGGAAAAAATTCACAAGTCGCAGTCATCAATACTATCATGCAAACTGCGGGAACGGTGGAAGCAAAcgtcacaaatgcaaattttgctCAAAGGAATTTCTTTCCTCGTCACACTTAAATTATCATGTGAAAAGTCATCATGAAATCAACAAGTATTCATGTAATTTATGCACGAAAACCTTTAGGCACATCATGAACTTGCGACGCCACAAACGCACGCACGATGgaatatataaatacaaatgcaagGAGTGTGGACTTGGTTTCCGAGAAACTAAAACATTAACCGCGCATATTAATAAGCATCGTAACATTTTCCCGTTTGTATGTAAAGTTTGCGGCAAAAAgttttcattcaaatcgaaTTTAACGCAACATCAAAAAATACATACAGGACTAGGCAAAAATTATCGTTGCGAAGATTGTGGTCGTGAATTCTTGCGGAAGAACTCGTATACGGAACATATGAATCGGCATGCAAAAGTGAAGAACTTTCAATGCAAATTGTGTCAAACATTGTTTATTGATAGAAAAACATTGGAACGACATATGAATACACATGGTTCCAAATACTACAACTGTCCACGTTGTGATGTAAAATGCGGCCGAAAAGACAACTTAGTTCGTCACATTCGAAATATGCATCCCAACGAGGATAtaaatgatattttgaaaaatatcaaaagtattGTCATTACAAATAAAGTCACAACGAAATCAAATCGCAATAAAGCGCATAAATCAAAATCCTCAACACAAGCAACAAATAGCAAAGATGATTTGGAATTGCCGAAAAGCGATAAATCATCAAAACCAATATTAGCCAGTACGTCTGTAATACGCTCAGTAGGCAATGTGAAACCTGTACAAATTCCCACAGTACATTGTGATTTAGATGGTAGTTCCACGCAACTGGGGTCAATTGCGCCGGCTACGCTGGCCGAAAAAGCTAATGATTGTGTtgtaaacaataataatgaatgCAGCCGTCAACAACCAACTATTAATCCACCGGCAGAGGCaaagaaaccaaagaaaaaatATGATCCGTGTGAGATATATCGAAAAATACTGTTCGCCAATGATACAGACGATTCAGTTTTGGAAACCGATGAATTTTATTCGCATTCGAAAGACGATCATGTGGGATGTTGTAACGATGAAAATCATGCGCTTGCTAAATCCTCAATGATGGTTGCTAGTTCTAATGAAAATTACACCAACACAAAGAGAATTACGGATAGTATGGAGCCATTAAATTTTGGTGAAATTCATTGGCGCAAGAGGACATcacagaattttcatacatcGCTTtaa
Protein Sequence
METSFCPRCNRMPVSPTNRLITERCGHVKCRECFINDLDGCYECLQGSTQSIPDAASTIERRIHQQVDCFENPLNIEGDSLALYNTVVEDSATFEGPATTKTSEPTSAAAVEPANSINVIHNYSTNDSQQQASDSTESFKILEEYIIPPKTKIEKFFRERKSLSGLYERKKGVPDYVEKSVEGGETFYKCNACGKKFTSRSHQYYHANCGNGGSKRHKCKFCSKEFLSSSHLNYHVKSHHEINKYSCNLCTKTFRHIMNLRRHKRTHDGIYKYKCKECGLGFRETKTLTAHINKHRNIFPFVCKVCGKKFSFKSNLTQHQKIHTGLGKNYRCEDCGREFLRKNSYTEHMNRHAKVKNFQCKLCQTLFIDRKTLERHMNTHGSKYYNCPRCDVKCGRKDNLVRHIRNMHPNEDINDILKNIKSIVITNKVTTKSNRNKAHKSKSSTQATNSKDDLELPKSDKSSKPILASTSVIRSVGNVKPVQIPTVHCDLDGSSTQLGSIAPATLAEKANDCVVNNNNECSRQQPTINPPAEAKKPKKKYDPCEIYRKILFANDTDDSVLETDEFYSHSKDDHVGCCNDENHALAKSSMMVASSNENYTNTKRITDSMEPLNFGEIHWRKRTSQNFHTSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-