Opun016790.1
Basic Information
- Insect
- Othius punctulatus
- Gene Symbol
- topi
- Assembly
- GCA_951805005.1
- Location
- OX638139.1:103660760-103663476[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00084 0.14 14.5 2.4 2 21 130 149 129 150 0.94 2 13 3.4e-05 0.0055 18.9 0.6 1 23 175 197 175 197 0.97 3 13 0.0097 1.6 11.2 1.9 3 23 205 225 204 225 0.95 4 13 1.3e-06 0.00022 23.3 2.0 2 23 329 350 328 350 0.97 5 13 0.48 78 5.8 0.0 1 21 356 376 356 377 0.88 6 13 0.092 15 8.1 3.6 2 22 393 413 392 416 0.87 7 13 0.15 24 7.4 0.3 1 23 550 573 550 573 0.96 8 13 0.068 11 8.5 0.3 1 23 577 599 577 599 0.97 9 13 1.7e-05 0.0027 19.9 5.4 1 23 605 627 605 627 0.98 10 13 0.034 5.4 9.5 0.2 1 23 633 658 633 658 0.96 11 13 0.17 27 7.3 2.9 1 23 664 686 664 686 0.86 12 13 2.1e-06 0.00034 22.7 0.5 1 23 692 714 692 714 0.98 13 13 1.5e-05 0.0024 20.0 1.9 1 23 720 743 720 743 0.98
Sequence Information
- Coding Sequence
- ATGAATAGAAATGAACATTTAACCTACCTAAAGCTACACAGGATCTTCACTGATGGTACGGTGCAGTCGCTGCAGCTGAAAATCGAGAGCGCTTCCCAAAAAATAATAGGCAAGCTACCGATCGCCCTAGAGCTACCCCCGATGTACACAGATATGAACCTGCCGAACAGCCCCGAGGAGGAGTTCAAGTTCAACTACTCGATGAACTTCAGTGACTCCTCTATTAGGGTCATCAAGCTGGGCGGAGTGGAGGACCTTAATCCTCTGAACTACGCGACCGAGATCTCCACTGTTTTGAGCGATCCCGGTGAATCAAAGGCGGCCAGGAACGTCTCGGCTGTCACACCGAAGCGGGAGTCGAAGGTGCCCAACATACCCACCATGATTCGGTGCCAGAACTGCGACACAAACTTCCCGACCAAGTATCAGTTCCAGAGGCACCAGTGCGAATTCAACGCAGAGAAAGTTGTTTTAAAACCCAATGTCGACGTGAAGGACGTGGAAAAAGGTGTCCGCATGAAATTCGACTGCCCAACGTGCGCCAAGCAGTTTGTAAGTAAGAATAATCTCGAACGGCATCTCACAAGCCACGACGAGGATAATGTTAATATATGCGAGTAttgcaataaacattttgtgagCGAGAACCGGTTGAGGATACATAAAGAGAACCACTGTAAAAAGGCAggtgatatttcaaaattttatcgcAGCGATGTTACCGTGTGGAAGTGCATTAAATgctaccaagtgttttcttccGATTCATATGCTAATGTGCACGCTGATATATGCTGCGAGATTTTGGATACTCATGAATTTAGGGAACTTAAAGCGTCCGAACCTGATGAAGACTCTTGCACGCTAAAGAAGGAAATTAAAACATTGTTAAACGAAGCTCCAGAGTTGGCGGAAGCCGAGGTTACTACAATTAATCTTAACACTAGTAAGTACGTGGAAAAGGTTATAACTGAACTTCTGTTGCAATGTGAGTATTGCAACAAAACTTATTCCGATAAAAAATCTCTTTTAATGCACCAAAGAACGCACACCACAGGAGTTAATTATAATTGCGTTATCTGCACTGAAACATTCGAGTCTTACGTGCTGGCAGCTAAGCATTGGCTTACAAAATGCTCCAATGAAGCAAACCTGTTCTACCTACCTAAGCTAACGTATTGCAGATACTGTGATCGCACATTTAAATCACACGAAGTTCTCTACTCCCATAAAATTAAGAAGAAGCATTACAGTcctaaaaaatgtattataagcAACTGCTATGATATGACAGAAGGGGAATgtgaaattatatcaaatgaCAATGGGGAAAACAAAgacacaattattaaattaatcgaGCGTGTAATGTGCTCGATCAAATCGAACGTCGACAGCCAAGAGTGCATTGAGGATGACGAGGACAGGGACGAAACCATTATAGACGATATAGGTGCCAACGAGATTTCTATAAAAACGGAAGTACCAAGCGAAACTAGTAGCCTCATAATATCAGAGGACGCACAAGACAGCGATATCCATGCTTCCGGGTGGAATTGGAAAAAGAAACGTGGTAGGAAAAGAAAGCATATGTCGCAGACGAATAAGGCTAAGCGTTTAGCTGCCAACGTTGACCCTGGGTATAAGTATCAGTGCGAACGCTGTATTAAAGTATTCGATAGTATACTAGATTTAGAAACGCATAGGGATAAAGACCATCCAGCTAATTATAAATGTGAAGAATGTGCTCAGGTGGTGCACAGTTCGAAAGCATTGCTGATCCACAGCAGGGCACATCAAAGTTTAAAACCGTACGTTTGCGAGATTTGTAAGCGGTGCTACTCGCAAACGTCTCATTTATGGCAGCACATGAGGTTCCATCAAGGGATAAAACCATTTGCCTGCCCCCATGAGGGCTGCGAGGCGAGGTACACAATAAGGCCGGATTTGAAAGATCACATTCGGAAAGTGCACACCAGGGAACGCCCGTTCAAATGTTCCGTCTGCGACAAGTGTTTTTTAACCGGATCCGTGTACTACCAGCACCGACTGATTCACACAAATGATCGAAGATATGCATGTGATatttGTAATAAGAGGTTTTTCCGGGCAGATGCTTTGAATAATCACAGGAGGATTCACACGGACGAGCGGCCTTATCCATGTGATGTATGCGGTAGGCATTTTAGACAGAAAGGTGATCGCAACAAGCATGTACGCACACAGCATCCGAACTATCATATTTAA
- Protein Sequence
- MNRNEHLTYLKLHRIFTDGTVQSLQLKIESASQKIIGKLPIALELPPMYTDMNLPNSPEEEFKFNYSMNFSDSSIRVIKLGGVEDLNPLNYATEISTVLSDPGESKAARNVSAVTPKRESKVPNIPTMIRCQNCDTNFPTKYQFQRHQCEFNAEKVVLKPNVDVKDVEKGVRMKFDCPTCAKQFVSKNNLERHLTSHDEDNVNICEYCNKHFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCIKCYQVFSSDSYANVHADICCEILDTHEFRELKASEPDEDSCTLKKEIKTLLNEAPELAEAEVTTINLNTSKYVEKVITELLLQCEYCNKTYSDKKSLLMHQRTHTTGVNYNCVICTETFESYVLAAKHWLTKCSNEANLFYLPKLTYCRYCDRTFKSHEVLYSHKIKKKHYSPKKCIISNCYDMTEGECEIISNDNGENKDTIIKLIERVMCSIKSNVDSQECIEDDEDRDETIIDDIGANEISIKTEVPSETSSLIISEDAQDSDIHASGWNWKKKRGRKRKHMSQTNKAKRLAANVDPGYKYQCERCIKVFDSILDLETHRDKDHPANYKCEECAQVVHSSKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYACDICNKRFFRADALNNHRRIHTDERPYPCDVCGRHFRQKGDRNKHVRTQHPNYHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -