Basic Information

Gene Symbol
-
Assembly
GCA_951805005.1
Location
OX638138.1:90752513-90757477[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.0096 1.6 11.2 0.1 5 21 1 17 1 18 0.93
2 24 1.5e-05 0.0024 20.0 1.4 3 23 27 47 27 47 0.99
3 24 0.00041 0.067 15.5 0.0 1 23 53 76 53 76 0.97
4 24 0.16 26 7.3 0.6 1 23 87 110 87 110 0.97
5 24 0.00033 0.053 15.8 0.1 1 23 116 138 116 138 0.95
6 24 2.1e-05 0.0035 19.5 2.6 1 23 144 166 144 166 0.98
7 24 0.00038 0.061 15.6 1.7 1 23 172 194 172 194 0.97
8 24 0.034 5.5 9.5 0.3 2 23 315 336 314 336 0.92
9 24 0.15 24 7.4 5.2 1 23 342 364 342 364 0.98
10 24 0.00032 0.052 15.8 2.2 1 23 370 392 370 392 0.96
11 24 0.00018 0.029 16.6 3.3 1 23 398 421 398 421 0.98
12 24 0.0029 0.47 12.8 2.8 1 23 433 456 433 456 0.95
13 24 0.0056 0.92 11.9 1.3 3 23 467 487 466 487 0.98
14 24 0.00015 0.024 16.9 2.4 3 23 495 515 493 515 0.97
15 24 3.5e-06 0.00057 22.0 0.7 1 23 521 543 521 543 0.98
16 24 2.3e-05 0.0038 19.4 1.4 2 23 602 623 601 623 0.97
17 24 0.0005 0.081 15.2 0.7 1 23 627 649 627 649 0.97
18 24 0.003 0.5 12.7 0.5 1 23 685 707 685 707 0.95
19 24 3e-05 0.0049 19.0 1.4 1 23 713 736 713 736 0.97
20 24 0.0064 1 11.7 3.1 1 23 747 769 747 769 0.94
21 24 9e-05 0.015 17.5 0.3 3 23 776 796 774 796 0.97
22 24 3.5e-05 0.0057 18.8 0.6 1 23 802 824 802 824 0.98
23 24 4.4e-07 7.2e-05 24.8 2.1 1 23 830 852 830 852 0.98
24 24 0.0015 0.24 13.7 0.2 1 22 858 879 858 879 0.96

Sequence Information

Coding Sequence
ATGTGCGGCAAAAACTTCACGACCTTCGAACTGCTCAATCTGCACATGAAGAGCCCGTGCAGGACCGTGCTCTGCGGCTGCTCGACCTGCGGGAAGATCTTCAAGAACAAGTCCCGCCTGAACGCCCACCTGCTGACGCACGCGGAGAAGCCGAAGTATCCGTGCGTCAAGTGCGGCAAGGAGCTGTCCAACACGATCGCCCTCCAGGCGCACATGGACACGATGCACACGGAGCACTTCGACGCGACCGCCGACGCCTTCAGGTGCAAGGTGTGCGAGATGCAGACGGCCACCAAGCTCCAGATCCTGAACCACATTAATTCAAAGCACCTGCACGTCAGCACGTTCTTGTGCGACGTGTGCGGCAAGAGCTTCCTGCAGGAGGGCGGCCTGAGGGCGCACATATCGACACACAGCAAGGAGAAGCCCTTCGTGTGCCATGTCTGCTCGAAGTCATTCAAGATGCAGAATACGCTTCGGGTTCATCTGGAGACGCACAGTGGCGAGAAACGGTTTATATGCGATGAGTGCGGCAAACCGCTGAAAAAGAAATCCACGCTCATTGAGCATAAGAAGCATCACGCCGGGGATTTCGCATTTCAGTGTAACATTTGCCTGAGGAAGTGCCAGATGGAACAGCATGCTCTTTTGAAGAACTTATTGTATGGCCCATCTATGTTGATTACAGTTCAACCGAAATTATCACCGGAGAGTGAAATATGCCCCGATTTAAAAGAGAGTAATTCAGAAGACGAGCTACCTTTGCATATCAGAAAGACCCagcaaaaaatcaaaatgaaaatgaaactaAACCAAAACTGCAACGCCAAAGTGGTGATTTCTAACTTGGCCAAGCGAAAAACCAAAATTAAGAAACCTCATCGCACCGATGACATCGACGGGGACGAGAACAGGGTTTTAGAGGACAAAGACGAGCCCATTCATTGTGATATATGTGACTTGGTTTTCAAGAACAACGTCGCCTTCGGTTTGCACTCAATCAAGCACAACAAAGACAGTCGGTACTCCTGCCACATGTGCAACTATACGTCGCTGTCGAAGTACCATTTTGAAATGCACATCCGTGCGCACGAGGGCACAACGGGGTACAAATGTGAGATCTGCAACAAGGCTTTCACCACGAGCACCCACGCTGCCGAGCACAAAAACTTCCACTCCGGTGAGAAGCCGTACCAGTGCGAGATATGTGGCAAGCACTTCATGTTCTCATGGTTCCTGACCTCGCACCGTCGCTCGCAGCACTGGGAGATTATGACGGGGATGCCGTTGGTAAAGTACGACTGCGTGACATGCAACAAGCACTACACGTCCGCCACCGGACTGCGCAGGCATAAGCTGAGCAAGCACAACGAGGAAGGCATCGATGCCAGCGTTTTGTGCGATATCTGCGGCAAGCGCCTTTCCAGCAAGGAGAAGCTGAAATTTCACAGGAGGATACACACCGGATACAAGCCGTACGGCTGTCAGACGTGCGCCAAGTGCTTCAGCCGCAAGGAGCAGCTGAAGGAGCACGAGCGCGTCCACACCGGCGAAAAGCCGTTCATATGCAACTTCTGCGGGAAGGGCTTCACGCAGCGGAGCCCCCTGAGGATCCACGAGAGGACTCATACAGGCGATCGGCCGTGCCTTCCGGATTATTTTCTGCCAGTTATAACGACGCTCGACGAAGAGTGCCCTCGAAAGCCACGACAAAGAAACATACGAAAGAAAGGATTCAAAACTAAAACTAATAAATGTGCAGTTAAGAAGGCGAAGGTTAAAACGTTCAAACTTGAAAGCCTGACGTGCGAGGTTTGctccaaaacttttaaaaccGTTAAAACACTAAGGGGCCACATGCGAAGTCATAACAAGCTATTCGACTGCTCGGAGTGCGACAAGAGTTTCGATAAAATCCTGAATTACATATTGCATCTTAAAACGCACGCCAGCGAAAACGACCAAATGAGCTGCATTTATTGCGAGTTTCAAACGGAAGACGTGGGCAAAATTACGCACCATCTTAACGAGATGCACGAGACTGTGCCGAAGTACTCGTGCCCAATTTGCAAGAAGGGGTTCAACGTGCTCACGTGGTTCACAGAACACGAGAACTTCCACACGGGCAATCGGCCGTTTACATGTGAATTCTGCGGTAAGGCGTTCATATATTCCAGGTACCTTACGGCTCACAAAAAGAGCATGCACAGCGAAGCGATAACCGGGATTTCCACTCTGCATGAGTGCATCATATGCAAGAAGGCTTACCAGCACAAGAACAGCCTGAAGGTTCACATGAACATACACACAGGAAACGTTTCGATATGTGATATATGCGGCAAGCAGTTGTCCAGCTCGGAAAAGTTAAAGTTGCATTTACGCATACATTCGGGTTACAAGCCGTTCAAATGCACGTACTGCGGGAAAGCTTTCACCAAGAAGCCGATCCTGACGGAGCACGTACGGATACACACGGGAGTCAAACCGTACAACTGCACCTATTGCAATAAGAATTTTTCGCAACGGTCCAGTCTCGTCATTCATATGAGGAACCACACGGGGGAAAGGCCGTACGTTTGCCACTTATGCGAGAAAGGGTTTGTCGCTAAGGCAATGCTTAATTTGCATCTGAGAAAATGCAACGGGTTTCTTATCgaataa
Protein Sequence
MCGKNFTTFELLNLHMKSPCRTVLCGCSTCGKIFKNKSRLNAHLLTHAEKPKYPCVKCGKELSNTIALQAHMDTMHTEHFDATADAFRCKVCEMQTATKLQILNHINSKHLHVSTFLCDVCGKSFLQEGGLRAHISTHSKEKPFVCHVCSKSFKMQNTLRVHLETHSGEKRFICDECGKPLKKKSTLIEHKKHHAGDFAFQCNICLRKCQMEQHALLKNLLYGPSMLITVQPKLSPESEICPDLKESNSEDELPLHIRKTQQKIKMKMKLNQNCNAKVVISNLAKRKTKIKKPHRTDDIDGDENRVLEDKDEPIHCDICDLVFKNNVAFGLHSIKHNKDSRYSCHMCNYTSLSKYHFEMHIRAHEGTTGYKCEICNKAFTTSTHAAEHKNFHSGEKPYQCEICGKHFMFSWFLTSHRRSQHWEIMTGMPLVKYDCVTCNKHYTSATGLRRHKLSKHNEEGIDASVLCDICGKRLSSKEKLKFHRRIHTGYKPYGCQTCAKCFSRKEQLKEHERVHTGEKPFICNFCGKGFTQRSPLRIHERTHTGDRPCLPDYFLPVITTLDEECPRKPRQRNIRKKGFKTKTNKCAVKKAKVKTFKLESLTCEVCSKTFKTVKTLRGHMRSHNKLFDCSECDKSFDKILNYILHLKTHASENDQMSCIYCEFQTEDVGKITHHLNEMHETVPKYSCPICKKGFNVLTWFTEHENFHTGNRPFTCEFCGKAFIYSRYLTAHKKSMHSEAITGISTLHECIICKKAYQHKNSLKVHMNIHTGNVSICDICGKQLSSSEKLKLHLRIHSGYKPFKCTYCGKAFTKKPILTEHVRIHTGVKPYNCTYCNKNFSQRSSLVIHMRNHTGERPYVCHLCEKGFVAKAMLNLHLRKCNGFLIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-