Basic Information

Insect: Osmia lignaria
Gene Symbol: zfh1
Assembly: GCA_012274295.1
Location: NW:6715038-6731860[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.4 28 4.6 2.4 2 23 91 113 91 113 0.90

2 7 1.5e-05 0.001 18.6 0.6 2 23 132 153 131 153 0.97

3 7 3.5e-06 0.00025 20.5 7.8 1 23 162 184 162 184 0.99

4 7 5.9e-05 0.0041 16.7 2.3 1 20 190 209 190 211 0.94

5 7 0.00014 0.0097 15.5 4.5 1 23 657 679 657 679 0.94

6 7 0.00035 0.024 14.2 8.9 1 23 685 707 685 707 0.98

7 7 0.00094 0.066 12.9 4.3 1 21 713 733 713 734 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.4	28	4.6	2.4	2	23	91	113	91	113	0.90
2	7	1.5e-05	0.001	18.6	0.6	2	23	132	153	131	153	0.97
3	7	3.5e-06	0.00025	20.5	7.8	1	23	162	184	162	184	0.99
4	7	5.9e-05	0.0041	16.7	2.3	1	20	190	209	190	211	0.94
5	7	0.00014	0.0097	15.5	4.5	1	23	657	679	657	679	0.94
6	7	0.00035	0.024	14.2	8.9	1	23	685	707	685	707	0.98
7	7	0.00094	0.066	12.9	4.3	1	21	713	733	713	734	0.96

Sequence Information

Coding Sequence: ATGAGCATGACTCTCGTCCGAAATACGTTCAAAGGTTGCAGCGAGGACGAGGCAGCAGGTGTCGTGAACGCGGAGGTGGGCGGAGGTTGCGCAGCCGGGGCGCCAACCACAGGAAGTAACGGTGGAGGTGGTAGCGGGACAGGTAGCGAGGTTGGTGGTGGCGGAGGAGGCGTTGGTGGTGGTGCAGGAACAGGAACaggaggtggtggtggtggtggtggtggccgTGGTAGCGGCGGTGAGGGCGGATCAACGAAGCAGGGTGGCGAGAGGTGTCCCCATTGTGGTATCCTCTGTCGGGACGTCCACGTGCTTCAGCTCCATCTCGAGGACACGCACAAGACCCCGTACGCCATCGACAAGAACGATCTCAACGCTCAATTCCCCCAAGTGTCCTGCAAGGTGTGCAGCAAGACTTTTGCTAACGTCTACCGACTCCAGAGGCACATGATCAGCCATGATGAAAGTGCCGTGCTTCGTAAGTTTAAGTGTCCCCATTGCGAGAAAGCCTTCAAGTTTAAGCATCACCTCAAGGAGCACCTTCGCATTCACAGCGGTGAAAAGCCATTCCAATGCAACAATTGCGGGAAACGTTTCTCTCATTCGGGCTCGTATTCGAGTCACACGACGTCGAAGAAGTGTCTGATAGTGAACTTAAAGAAATCAAGGCACACGAACGTGAGCAATGTAGATCGTGGCTCGAAAAAAGTGCAACAACCCCTGCCGCCGGGACGTCGCGAGGTCGATCTGCTCGCGGCGAATAATAACACTTTCCTCCCTATTCTGCCGAAGCTTTCACCCTCGGATTACCAGGAAATACAACGAGAAGGAGCGGgTATTTACGATATGCCGACCCTCTTGCCTCAAATGATGGGTTTCGGTAGTTACTTCCTACGGATGTCCTTGGGCAAGATCTTAACTCAGCTACATTCCAAGAGATTGGACGAGGTAGCCGAGCAATTCGAGTCTCATCGAGAGCTTATGAGTCCATCCACCGCGGATTCGGAGGGCACCGAGGGCACCGAGGGCAAAGAATCACCGGCGCCCGCAGATCCTCAGGGTCTCGACGCTGTTCGAAGAATTTTGGAAACCGTCAACACCTCTGTCACGAAACAATTACTGGAAGCGAACGTACGAAAGTTGTCTACCTCACCAGCGACGATGAAACGGGAGTTCGAGGAGGATTATCAAGATCAAGATAGCGAAATGTCGAGCGAGATGGCACACTATCCGGACTGGTCAACGACGGATCAATATGATTCGCAGAGCGAGGGTTTAGCGGCGAAGCTCGAGGACGTAAATCAACCGAGCGCGAAATCAGGCTACAAAAGAAAAGCGGAGGACAGCTCGGAAGCTGACTCGGACGACGATGAAGATGGAACCCAAACGCACAACGATAATGGAAGGAGAGTTAGAGCAAGGTCGTTGATAGACGACGAGCAATTGGCTGTTCTCAAAGGTTACTATGCCATTAATCCTCGGCccaaaaaggaagaaatcaTCATGATAGCGAATTATATCAATTTCCCCACCCGTGTCGTACAGGTTTGGTTCCAAAATTCCCGAGCGAGAGATCGACGAGAATCGAAGATACCACCTCTTGTGCCACTTGCTAATTCGATCAGTCAGACTACCATCGAACAACCCCTCGATCtgtcgaagaaagaaggacTCACGCAGTCAACGTGTAAAGAGAACGATGTTGTCTCGGTCAAACAAGCGCCCTCGCCTCCTGTCGAACTGAAGAATGATCATCCACCGACGCATAACCCAGACACGGATGATTTGGAGGATTCACCGCTCGTTATAGACGAAGAGACTACCGATTCCGTGGAAACGAAACGTTTAGTCCCTACCACAGGGGGAGAAATTGGTCCAAAGAGTCAACCTCAAACGAATACGAAGAGTGAAAGTGAAAACGTTAGTAAACCAGAGGCCCCGCCAGCGGCGGAAATCGAGCAGGGCGTTTACTTCTGTGATCGGTGTGACAAAACATTCTCCAAGCACAGTTCCCTAGCAAGACACAAATATGAACATTCCGGGCAAAGGCCGTACAAATGCATGGAGTGCACAAGGGCGTTCAAGCACAAGCACCATCTGACCGAACACAAGCGGCTGCACAGCGGGGAAAAGCCCTTCCAATGCTCCAAGTGCCTGAAGCGTTTCTCTCACTCGGGCTCGTACAGCCAGCACATGAATCATCGTTACTCTTACTGCAAGCCGTACAGAGAATAG
Protein Sequence: MSMTLVRNTFKGCSEDEAAGVVNAEVGGGCAAGAPTTGSNGGGGSGTGSEVGGGGGGVGGGAGTGTGGGGGGGGGRGSGGEGGSTKQGGERCPHCGILCRDVHVLQLHLEDTHKTPYAIDKNDLNAQFPQVSCKVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHTTSKKCLIVNLKKSRHTNVSNVDRGSKKVQQPLPPGRREVDLLAANNNTFLPILPKLSPSDYQEIQREGAGIYDMPTLLPQMMGFGSYFLRMSLGKILTQLHSKRLDEVAEQFESHRELMSPSTADSEGTEGTEGKESPAPADPQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKREFEEDYQDQDSEMSSEMAHYPDWSTTDQYDSQSEGLAAKLEDVNQPSAKSGYKRKAEDSSEADSDDDEDGTQTHNDNGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIMIANYINFPTRVVQVWFQNSRARDRRESKIPPLVPLANSISQTTIEQPLDLSKKEGLTQSTCKENDVVSVKQAPSPPVELKNDHPPTHNPDTDDLEDSPLVIDEETTDSVETKRLVPTTGGEIGPKSQPQTNTKSESENVSKPEAPPAAEIEQGVYFCDRCDKTFSKHSSLARHKYEHSGQRPYKCMECTRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086058;
90% Identity: iTF_00964367;
80% Identity: iTF_01122974;